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Bioconjugation Jobs (NOW HIRING)

Thermo Fisher Scientific

R&D Scientist III

Fremont, CA · On-site

$100K - $133K/yr

Apply your hands-on expertise in organic synthesis, bioconjugation, and analytical chemistry to deliver consistent, high-performance materials that support diagnostic innovation. Location: Fremont ...

Waters Corporation

Sr Scientist

Milford, MA · On-site

$100K - $137K/yr

Experience with different solid surface bioconjugation approaches and the quantification of biomolecules immobilized to solid surface. * Knowledge of liquid chromatography principles and material ...

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Bioconjugation information

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$30

$61

$92

How much do bioconjugation jobs pay per hour?

As of Jun 29, 2026, the average hourly pay for bioconjugation in the United States is $61.42, according to ZipRecruiter salary data. Most workers in this role earn between $42.55 and $73.80 per hour, depending on experience, location, and employer.

What is the difference between Bioconjugation vs Protein Conjugation?

AspectBioconjugationProtein Conjugation
Required CredentialsBiochemistry, Molecular Biology certificationsBiochemistry, Molecular Biology certifications
Work EnvironmentLaboratories, biotech companiesLaboratories, biotech companies
Industry UsageDrug development, diagnostics, researchDrug development, diagnostics, research
Common Search IntentUnderstanding bioconjugation techniquesUnderstanding protein conjugation methods

Bioconjugation involves attaching biomolecules like drugs, antibodies, or peptides to other molecules for various applications. Protein conjugation specifically focuses on linking proteins to other molecules, often as part of bioconjugation processes. While both roles require similar skills and work environments, bioconjugation covers a broader range of biomolecules, whereas protein conjugation is specialized in working with proteins. Understanding these differences helps professionals and employers target the right expertise for biotech projects.

What is bioconjugation?

Bioconjugation is the process of chemically linking two molecules, at least one of which is a biological molecule such as a protein, peptide, or antibody. This technique is commonly used to attach drugs, fluorescent dyes, or other markers to biomolecules for research, diagnostic, or therapeutic purposes. Bioconjugation plays a crucial role in developing targeted drug delivery systems, biosensors, and imaging agents. The process requires careful selection of conjugation chemistries to preserve the function of the biomolecules involved.

What are the key skills and qualifications needed to thrive in a bioconjugation scientist role, and why are they important?

To thrive as a bioconjugation scientist, you need a solid background in chemistry or biochemistry, experience with protein modification techniques, and typically a relevant advanced degree. Familiarity with analytical tools like HPLC, mass spectrometry, and knowledge of Good Laboratory Practice (GLP) or GMP guidelines is common, along with experience using laboratory information management systems (LIMS). Strong problem-solving skills, attention to detail, and effective communication are crucial soft skills for collaborating across research teams and troubleshooting experimental challenges. These competencies ensure the efficient development of high-quality bioconjugates for applications in therapeutics, diagnostics, or research.

What are some common challenges faced by professionals working in bioconjugation, and how can they be addressed?

One common challenge in bioconjugation roles is ensuring the specificity and stability of the conjugates produced, as improper coupling can affect the efficacy and safety of the final product. Additionally, troubleshooting complex reactions and optimizing protocols for scale-up requires strong problem-solving skills and familiarity with analytical techniques. Effective collaboration with cross-functional teams such as analytical chemistry, process development, and quality assurance is vital to overcoming these obstacles and ensuring project success. Staying updated with the latest advances in conjugation chemistries and regulatory requirements also helps professionals adapt to the evolving landscape.
More about Bioconjugation jobs
What cities are hiring for Bioconjugation jobs? Cities with the most Bioconjugation job openings:
What states have the most Bioconjugation jobs? States with the most job openings for Bioconjugation jobs include:
What job categories do people searching Bioconjugation jobs look for? The top searched job categories for Bioconjugation jobs are:
Bioconjugation jobs near you

Director, Chemistry, Next Generation Genetic Medicine

Ignite Human Capital

San Diego, CA • On-site

$150K - $185K/yr

Full-time

Medical, Dental, Vision, Life, Retirement, PTO

Posted 23 days ago

Key responsibilities

  • Lead scientific strategy and execution for conjugation chemistry and targeted delivery approaches across oligonucleotide therapeutic programs.

  • Drive innovation in conjugation design, chemical optimization, and ligand-mediated delivery technologies.

  • Lead multidisciplinary teams advancing programs from discovery through IND-enabling studies.

Job description

Ignite Human Capital is proud to represent a confidential client — a cutting-edge, early-stage genetic medicine company pioneering RNA-targeted therapeutics. This organization is developing novel approaches to precisely correct disease-causing mutations at the RNA level, with the potential to address conditions long considered undruggable. Backed by strong science and a focused leadership team, the company is advancing its pipeline through IND-enabling studies and beyond.

The Director, Chemistry will serve as a key scientific and strategic leader, owning the design, optimization, and advancement of next-generation oligonucleotide therapeutics — with particular focus on conjugation chemistry and targeted delivery technologies.

What you'll do
  • Lead scientific strategy and execution for conjugation chemistry and targeted delivery approaches across oligonucleotide therapeutic programs.
  • Drive innovation in conjugation design, chemical optimization, and ligand-mediated delivery technologies.
  • Establish and advance platform capabilities in bioconjugation, receptor/ligand targeting, and extrahepatic delivery systems.
  • Lead multidisciplinary teams advancing programs from discovery through IND-enabling studies.
  • Design and optimize conjugation strategies to improve potency, stability, pharmacokinetics, tissue specificity, and therapeutic index.
  • Collaborate with biology, DMPK, toxicology, translational sciences, and clinical development teams to drive candidate selection and advancement.
  • Identify, assess, and integrate novel conjugation chemistries, targeting ligands, and delivery technologies, including antibody-oligonucleotide conjugates (AOCs).
  • Build, mentor, and inspire high-performing scientific teams; foster a collaborative and innovative culture.
  • Present scientific findings and strategic recommendations to executive leadership and external collaborators.
  • Support external partnerships, collaborations, and diligence activities related to delivery and conjugation technologies.
  • Stay current with scientific advancements and the competitive landscape in oligonucleotide therapeutics and conjugate technologies.
What you'll bring
  • Ph.D. in Chemistry, Medicinal Chemistry, Pharmaceutical Sciences, or a related scientific discipline.
  • 10+ years of industry experience in oligonucleotide therapeutics, conjugation chemistry, or targeted delivery platforms within biotech or pharma.
  • Demonstrated success advancing therapeutic programs from discovery through IND-enabling studies.
  • Strong experience with ligand-mediated delivery, receptor targeting, and extrahepatic delivery approaches.
  • Deep expertise in bioconjugation technologies and emerging delivery modalities.
  • Proven leadership managing cross-functional scientific teams and complex research programs.
  • Strong understanding of pharmacology, DMPK, biodistribution, and translational considerations for oligonucleotide therapeutics.
  • Excellent communication, collaboration, and strategic leadership skills.
Compensation & benefits

Our client offers a highly competitive compensation package including base salary, annual performance bonus, and equity awards. Benefits include medical, dental, and vision insurance, life insurance, 401(k) with matching, generous PTO, paid holidays, and an Employee Assistance Program.

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