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Bioconjugation Jobs (NOW HIRING)

MacroGenics

Scientist I/II - Bioconjugation

Rockville, MD · On-site

$86 - $146/hr

Develop and optimize bioconjugation processes for ADCs, DACs, and related targeted therapeutics. * Synthesize, and optimize novel linker-payload molecules, directly contributing to next-generation ...

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How much do bioconjugation jobs pay per hour?

As of Sep 7, 2026, the average hourly pay for bioconjugation in the United States is $61.42, according to ZipRecruiter salary data. Most workers in this role earn between $42.55 and $73.80 per hour, depending on experience, location, and employer.

What is bioconjugation?

Bioconjugation is the process of chemically linking two molecules, at least one of which is a biological molecule such as a protein, peptide, or antibody. This technique is commonly used to attach drugs, fluorescent dyes, or other markers to biomolecules for research, diagnostic, or therapeutic purposes. Bioconjugation plays a crucial role in developing targeted drug delivery systems, biosensors, and imaging agents. The process requires careful selection of conjugation chemistries to preserve the function of the biomolecules involved.

What are the key skills and qualifications needed to thrive in a bioconjugation scientist role, and why are they important?

To thrive as a bioconjugation scientist, you need a solid background in chemistry or biochemistry, experience with protein modification techniques, and typically a relevant advanced degree. Familiarity with analytical tools like HPLC, mass spectrometry, and knowledge of Good Laboratory Practice (GLP) or GMP guidelines is common, along with experience using laboratory information management systems (LIMS). Strong problem-solving skills, attention to detail, and effective communication are crucial soft skills for collaborating across research teams and troubleshooting experimental challenges. These competencies ensure the efficient development of high-quality bioconjugates for applications in therapeutics, diagnostics, or research.

What are some common challenges faced by professionals working in bioconjugation, and how can they be addressed?

One common challenge in bioconjugation roles is ensuring the specificity and stability of the conjugates produced, as improper coupling can affect the efficacy and safety of the final product. Additionally, troubleshooting complex reactions and optimizing protocols for scale-up requires strong problem-solving skills and familiarity with analytical techniques. Effective collaboration with cross-functional teams such as analytical chemistry, process development, and quality assurance is vital to overcoming these obstacles and ensuring project success. Staying updated with the latest advances in conjugation chemistries and regulatory requirements also helps professionals adapt to the evolving landscape.

What is the difference between Bioconjugation vs Protein Conjugation?

AspectBioconjugationProtein Conjugation
Required CredentialsBiochemistry, Molecular Biology certificationsBiochemistry, Molecular Biology certifications
Work EnvironmentLaboratories, biotech companiesLaboratories, biotech companies
Industry UsageDrug development, diagnostics, researchDrug development, diagnostics, research
Common Search IntentUnderstanding bioconjugation techniquesUnderstanding protein conjugation methods

Bioconjugation involves attaching biomolecules like drugs, antibodies, or peptides to other molecules for various applications. Protein conjugation specifically focuses on linking proteins to other molecules, often as part of bioconjugation processes. While both roles require similar skills and work environments, bioconjugation covers a broader range of biomolecules, whereas protein conjugation is specialized in working with proteins. Understanding these differences helps professionals and employers target the right expertise for biotech projects.

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What states have the most Bioconjugation jobs?

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What job categories do people searching Bioconjugation jobs look for?

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Bioconjugation jobs near you
Infographic showing various Bioconjugation job openings in the United States as of August 2026, with employment types broken down into 92% Full Time, 2% Temporary, and 6% Contract. Highlights an 97% Physical, 2% Hybrid, and 1% Remote job distribution, with an average salary of $127,745 per year, or $61.4 per hour.

Process Development Engineer II - Synthetic and Bioconjugation Scale-Up Technologies (SBST)

Regeneron Pharmaceuticals, Inc.

Tarrytown, NY • On-site

Full-time

Medical, Dental, Vision, Life, Retirement, PTO

Posted 7 days ago

Regeneron rating

8.5

Company rating: 8.5 out of 10

Based on 44 frontline employees who took The Breakroom Quiz

19th of 86 rated pharmaceutical

Job description

Build our future together:
At Regeneron, we use science and innovation to develop life-changing medicines for people with serious diseases. We are seeking a Process Development Engineer II to join our Preclinical Manufacturing & Process Development (PMPD) group, supporting the new Synthetic and Bioconjugation Scale-up Technologies (SBST) team. You'll develop conjugation and purification processes for bioconjugation of proteins to a diverse range of synthetic molecules, working closely with cross-functional teams to apply Quality by Design (QbD) principles that make processes suitable for GMP production. You'll also support process scale-up and technology transfer of manufacturing workflows to Contract Development and Manufacturing Organizations (CDMOs) or Regeneron-based manufacturing suites, helping ensure timely and reliable progress from clinic to commercialization.
This position offers the opportunity to contribute to a fast-growing, science-driven organization making a meaningful difference to patients worldwide.
When & where:
Location: Tarrytown, NY
Work model/flexibility: Onsite, full-time
Discover your role:
  • Works at the bench to design and develop scalable, robust and controlled GMP-ready bioconjugation and purification processes
  • Collaborates with analytical groups within or outside the organization to establish supportive analytical characterization techniques
  • Discusses plans and data in cross-functional teams to evaluate processes and determine developmental goals, ensuring integrated program success
  • Proactively complies with lab safety and environmental safety expectations of both Regeneron and regulatory bodies such as the FDA and Department of Transportation (DoT)
  • Uses statistical design of experiments (DOE) to optimize bioconjugation processes, including conjugation reactions, purification operations, and analytical characterization
  • Partners with the External Manufacturing group and other key partners at Regeneron's IOPS organization to provide technical assessment of CDMOs intended for GMP production, successfully transferring processes with immediate, first-time success
  • Researches, identifies, and develops new technologies to improve processes, generate predictive process models, and pioneer novel at-line/in-line process analytical technologies (PAT)
  • Authors robust technology transfer documentation and supports production with onsite presence during scale-up/GMP manufacturing activities
  • Analyzes and presents data in a clear and cohesive manner to a broad audience, facilitating data-driven decision making
  • Authors, reviews, or provides domain expertise for publications, reports, tech transfer documents, regulatory support documents, and patents
  • Acts as a responsible lab citizen by ensuring timely maintenance of lab equipment, keeping the lab tidy and organized, and proactively planning for lab resources
  • Coaches and mentors junior team members of the organization as needed

This role requires:
  • Bachelor's degree + 5-6 years relevant experience, or Master's degree + 3-4 years relevant experience, in chemical/biochemical engineering or a related field
  • Experience with antibodies in the bioconjugates space is highly preferable
  • Hands-on experience with bioconjugation processes (lysine-based, cysteine-based, site-specific, etc.) with practical knowledge of downstream purification techniques such as chromatography, ultrafiltration/diafiltration, and membrane technologies is preferred
  • Experience with a variety of analytical characterization tools such as electrophoresis, mass spectrometry, high-performance liquid chromatography (HPLC), and UV spectroscopy is preferred
  • Strong initiative with the drive to complete challenging tasks and learn new technologies
  • Strong fundamental understanding of protein purification and technology transfer principles
  • Capable of multi-tasking and working both independently and in a collaborative, cross-functional environment
  • Excellent interpersonal, verbal, and written communication skills
  • Strong critical thinking and problem-solving skills

#pmpd
Does this sound like you? Apply now to take your first step towards living the Regeneron Way! We are committed to building a workplace with an inclusive culture. Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion or belief (or lack thereof), sex, sexual orientation, gender identity or expression, gender reassignment, marital or civil partnership status, civil status, pregnancy or parental status, age, disability, nationality, citizenship status, ethnic or national origin, membership of the Traveler community, familial status, genetic information, military or veteran status, or any other characteristic protected under applicable law. Where required, we will provide reasonable accommodation to applicants with known disabilities or chronic illnesses during the recruitment process, unless such accommodation would impose undue hardship.
Where necessary, we disclose salary ranges for roles in all countries in which we operate. The final offer will be determined within the relevant range based on the country of employment, specific role level, and your skills and experience. In some countries, collective bargaining agreements (CBAs) may apply and influence certain elements of pay or benefits. Regeneron offers a competitive and comprehensive total rewards package which may include, depending on country and role: annual bonuses or other incentive plans, equity awards, pension or retirement benefits, 401(k) company match, health and wellness programs, fitness centers, insurance benefits (e.g. medical, dental, vision, life and disability), paid time off, and family support benefits. For additional information about Regeneron benefits in the U.S., please visit https://careers.regeneron.com/en/working-at-regeneron/total-rewards/. For other locations, additional information will be provided during the recruitment process. If you have any questions, please speak with your recruiter.
Please be advised that at Regeneron, we believe we do our best work when we are together. For that reason, many roles are required to be performed on-site. Please speak with your recruiter and hiring manager for more information about on-site expectations for your role and location.
As part of the recruitment process, certain background checks may be conducted in accordance with the laws of the country where the position is based. The purpose of such checks is to verify certain information prior to the commencement of employment such as identity, right to work and educational qualifications.
For jobs in Canada: this posting is for an existing position.
Salary Range (annually)
$93,900.00 - $153,300.00

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