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Bioconjugation Scientist Jobs (NOW HIRING)

Nurix

Senior Scientist, Antibody Conjugation

Brisbane, CA · On-site

$110K - $150K/yr

Develop and optimize antibody bioconjugation methods for attaching degrader payloads and linkers to antibodies. * Design conjugation chemistry with an eye toward automation: define protocols, reagent ...

Nurix

Senior Scientist, Antibody Conjugation

Brisbane, CA · On-site

$110K - $150K/yr

Develop and optimize antibody bioconjugation methods for attaching degrader payloads and linkers to antibodies. * Design conjugation chemistry with an eye toward automation: define protocols, reagent ...

Cellanome

Staff Scientist, Chemistry

Foster City, CA · On-site

$140K - $200K/yr

You will be responsible for developing novel chemistries, bioconjugation methods, materials ... related scientific discipline, with a minimum of 5 years of relevant experience. * Extensive ...

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How much do bioconjugation scientist jobs pay per year?

As of Aug 21, 2026, the average yearly pay for bioconjugation scientist in the United States is $112,400.00, according to ZipRecruiter salary data. Most workers in this role earn between $105,000.00 and $120,500.00 per year, depending on experience, location, and employer.

What is a bioconjugation scientist?

A Bioconjugation Scientist specializes in developing and optimizing techniques to attach biomolecules, such as proteins, peptides, or antibodies, to other molecules like drugs, fluorophores, or nanoparticles. This work is critical in biopharmaceuticals, diagnostics, and drug delivery systems. They design and perform chemical or enzymatic conjugation reactions, analyze conjugates for stability and functionality, and troubleshoot process challenges. Additionally, they collaborate with cross-functional teams to improve bioconjugation strategies for therapeutic and diagnostic applications.

What are the typical daily responsibilities of a bioconjugation scientist?

A Bioconjugation Scientist typically spends their day designing and performing experiments to create and characterize conjugates of biomolecules, such as antibodies, proteins, or nucleic acids, with various chemical tags or drugs. Routine responsibilities include preparing reagents, optimizing reaction conditions, running purification and analytical assays, and documenting results in laboratory notebooks or electronic systems. Collaboration with cross-functional teams—such as analytical chemistry, biology, or process development—is frequent to ensure projects move efficiently from research to development stages. This role often requires meticulous attention to experimental detail, the ability to manage multiple projects simultaneously, and strong data interpretation skills. Regular team meetings and presentations are also common aspects of the work environment.

What are the key skills and qualifications needed to thrive as a bioconjugation scientist?

To thrive as a Bioconjugation Scientist, you need a strong background in chemistry, biochemistry, or related life sciences, with hands-on experience in protein modification, organic synthesis, and analytical techniques. Familiarity with tools such as HPLC, mass spectrometry, and relevant software for data analysis is common, along with knowledge of GLP/GMP practices. Strong problem-solving skills, attention to detail, and clear communication are vital soft skills for collaborating on interdisciplinary research projects. These capabilities enable precise and efficient development of bioconjugated molecules for applications in diagnostics, therapeutics, and biotechnology.

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Bioconjugation Scientist jobs near you
Infographic showing various Bioconjugation Scientist job openings in the United States as of August 2026, with employment types broken down into 1% Internship, 1% As Needed, 82% Full Time, 12% Part Time, and 4% Contract. Highlights an 82% Physical, 3% Hybrid, and 15% Remote job distribution, with an average salary of $112,400 per year, or $54 per hour.

Senior Scientist, Protein and Antibody Bioconjugation

Neurocrine Biosciences, Inc.

San Diego, CA • On-site

$97K - $132K/yr

Full-time

Medical, Dental, Vision, Retirement, PTO

Re-posted 18 days ago

Job description

Who We Are:
Neurocrine Biosciences is a leading biopharmaceutical company with a simple purpose: to relieve suffering for people with great needs. We are dedicated to discovering, developing and commercializing life-changing treatments for patients with under-addressed neurological, psychiatric, endocrine and immunological disorders. The company's diverse portfolio includes FDA-approved treatments for tardive dyskinesia, chorea associated with Huntington's disease, classic congenital adrenal hyperplasia, hyperphagia in patients with Prader-Willi syndrome, endometriosis* and uterine fibroids*, as well as a robust pipeline including multiple compounds in mid- to late-phase clinical development across our core therapeutic areas. For more than three decades, we have applied our unique insight into neuroscience and the interconnections between brain and body systems to treat complex conditions. We relentlessly pursue medicines to ease the burden of debilitating diseases and disorders, because you deserve brave science. For more information, visit neurocrine.com, and follow the company on LinkedIn, X, Facebook and YouTube. (*in collaboration with AbbVie)
About the Role:
We seek a Bioconjugation Sr. Scientist to join our Bioconjugates Research Group. The successful candidate will contribute to the design, generation, and characterization of novel bioconjugate modalities, including antibody-peptide conjugates (APC), antibody-oligonucleotides conjugates (AOC), and antibody-drug conjugates (ADC). Your expertise in protein and antibody conjugation will enable you to have a significant impact on Neurocrine's pipeline of innovative therapeutics.
Your Contributions (include, but are not limited to):
  • Carry out laboratory functions, plan and design experiments, and apply technical knowledge and skills to achieve project goals in a precise and timely manner
  • Design, synthesize, and characterize antibody conjugates using state-of-the-art bioconjugation methods, purification processes, and biophysical techniques
  • Optimized conjugation protocols using novel chemistries and techniques for a variety of bioconjugates modalities such as peptide-antibody (APC), oligonucleotides-antibody (AOC) and small molecule antibody (ADC) conjugates. Experience with different conjugation strategies, such as stochastic vs site-specific conjugation, is desirable
  • Identify and troubleshoot critical issues within conjugation processes, resolving them promptly to ensure consistent progress and quality
  • Collaborate cross-functionally with chemists and other teams to design and establish linker-payload biologic SAR (structure-activity relationships), supporting scientific discovery and project progression
  • Tracks progress against the timelines of ongoing projects, ensuring timely delivery of results and providing regular updates to project teams and stakeholders
  • Effective communication of scientific rationale, results, and interpretation at project, team and departmental meetings, contributing to strategic discussions
  • Establish and maintain excellent working relationships with critical collaborators throughout the company
  • Maintains accurate and well-organized lab notebooks and batch records to document all experimental procedures and findings, ensuring compliance with regulatory requirements and internal standards
  • Represents our function in cross-functional meetings and contributes to decision-making at the program level, driving strategy, execution, and delivery of critical milestones. Communicate scientific rationale, data, and interpretations effectively in project, team, and departmental meetings
  • Contribute to project and platform strategy, including proposing new technologies, approaches, or areas of exploration

Requirements:
  • BS/BA degree in biology and 4+ years of relevant industry experience OR
  • MS/MA degree in biology and 3+ years of relevant industry experience OR
  • PhD or equivalent and some relevant experience
  • In-depth knowledge of modern protein bioconjugation (peptide, protein, and antibody) purification, and analytical characterization
  • Hands-on experience with antibody conjugates with various payload classes, including peptides, oligonucleotides, and small molecules. Experience with different conjugation strategies, such as stochastic vs site-specific conjugation, is an advantage
  • Strong background in analytical characterization of bioconjugates, specifically RP-HPLC, LC-MS
  • Proficiency in purification techniques for antibodies and antibody conjugates such as RP-HPLC, FPLC-AKTA, size-exclusion (SEC), ion exchange (IEX), tangential flow filtration (TFF)
  • Independently design and implement conjugation and purification strategies applying stay-of-the-art knowledge in the field
  • Strong publication record of accomplishment
  • Understanding of peptide, siRNA, and protein structure and associated biophysical techniques to assess structure, stability, and behavior in solution is desirable
  • Experience in formulation strategies for conjugate molecules is a plus
  • Excellent interpersonal skills with strong oral and written communication abilities
  • Assimilates data and research findings outside of Neurocrine and applies them to new scientific projects
  • Prioritizes teamwork above all else
  • Must be able to work independently with supervision as needed
  • Understands the team's role within the larger organization and can discuss changes, progress, and issues in relation to other areas
  • Excellent written and verbal communication skills, with the ability to present complex scientific data clearly to diverse audiences
  • Demonstrates strong problem-solving and analytical thinking skills, showing a proactive attitude towards exploring new approaches
  • Maintains a comprehensive knowledge of principles and theories, providing solutions to a wide range of complex problems
  • Able to meet multiple deadlines across various projects/programs with a high degree of accuracy and efficiency
  • High attention to detail and commitment to data integrity, reproducibility, and quality documentation

#LI-LS1
Neurocrine Biosciences is an EEO/Disability/Vets employer.
We are committed to building a workplace of belonging, respect, and empowerment, and we recognize there are a variety of ways to meet our requirements. We are looking for the best candidate for the job and encourage you to apply even if your experience or qualifications don't line up to exactly what we have outlined in the job description.
The annual base salary we reasonably expect to pay is $110,800.00-$151,000.00. Individual pay decisions depend on various factors, such as primary work location, complexity and responsibility of role, job duties/requirements, and relevant experience and skills. In addition, this position offers an annual bonus with a target of 20% of the earned base salary and eligibility to participate in our equity based long term incentive program. Benefits offered include a retirement savings plan (with company match), paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage in accordance with the terms and conditions of the applicable plans.

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