... DMPK, biodistribution, and delivery platform evaluation). * Contribute to evaluation of new delivery approaches, Lipid and RNA components, and emerging targets to support pipeline expansion. * Assist ...
... DMPK, biodistribution, and delivery platform evaluation). * Contribute to evaluation of new delivery approaches, Lipid and RNA components, and emerging targets to support pipeline expansion. * Assist ...
... DMPK, and toxicology. Key Responsibilities Discovery Strategy & Scientific Leadership * Define and lead the end-to-end discovery strategy for antiviral programs * Drive target identification and ...
... DMPK, and toxicology. Key Responsibilities Discovery Strategy & Scientific Leadership * Define and lead the end-to-end discovery strategy for antiviral programs * Drive target identification and ...
Director Business Development- Discovery Services
Exton, PA ยท On-site
$120K - $170K/yr
... DMPK,), safety and toxicology, CMC and API manufacture, laboratory testing services and early ... * Assist with preparing proposals, quotes, and customer contracts. * Develop a comprehensive ...
Quick apply
Director Business Development- Discovery Services
Exton, PA ยท On-site
$120K - $170K/yr
... DMPK,), safety and toxicology, CMC and API manufacture, laboratory testing services and early ... * Assist with preparing proposals, quotes, and customer contracts. * Develop a comprehensive ...
Research Assistant/Research Associate
Hayward, CA ยท On-site
$65K - $85K/yr
Medical
Dental
Life
Retirement
Research Assistant/Research Associate Department: ADME Department Location: Hayward, CA (on-site ... Work experience in cell-culture or in an in vitro ADME/DMPK lab preferred but not required. * A ...
Quick apply
Research Assistant/Research Associate
Hayward, CA ยท On-site
$65K - $85K/yr
Medical
Dental
Life
Retirement
Research Assistant/Research Associate Department: ADME Department Location: Hayward, CA (on-site ... Work experience in cell-culture or in an in vitro ADME/DMPK lab preferred but not required. * A ...
Director Business Development-West Coast
Hayward, CA ยท On-site
$120K - $160K/yr
Medical
Dental
Vision
Life
Retirement
PTO
The Director of Business Development supports PK/DMPK and Safety & Toxicology Services business ... Assist with preparing proposals, quotes, and customer contracts. o Develop a comprehensive ...
Quick apply
Director Business Development-West Coast
Hayward, CA ยท On-site
$120K - $160K/yr
Medical
Dental
Vision
Life
Retirement
PTO
The Director of Business Development supports PK/DMPK and Safety & Toxicology Services business ... Assist with preparing proposals, quotes, and customer contracts. o Develop a comprehensive ...
Receptionist / Administrative Assistant
Newark, DE ยท On-site
$19 - $20/hr
Life
Retirement
... DMPK, Toxicology, Bioanalysis, Translational Medicine, Early Phase Clinical and Phase II - IV ... The Job * Greet and assist visitors, employees, vendors, and callers in a professional and ...
New
Quick apply
Receptionist / Administrative Assistant
Newark, DE ยท On-site
$19 - $20/hr
Life
Retirement
... DMPK, Toxicology, Bioanalysis, Translational Medicine, Early Phase Clinical and Phase II - IV ... The Job * Greet and assist visitors, employees, vendors, and callers in a professional and ...
New
Senior Scientist, Safety Assessment
Cambridge, MA ยท On-site
Medical
Dental
Vision
Life
Retirement
PTO
... DMPK, biodistribution, and delivery platform evaluation). * Contribute to evaluation of new delivery approaches, Lipid and RNA components, and emerging targets to support pipeline expansion. * Assist ...
Senior Scientist, Safety Assessment
Cambridge, MA ยท On-site
Medical
Dental
Vision
Life
Retirement
PTO
... DMPK, biodistribution, and delivery platform evaluation). * Contribute to evaluation of new delivery approaches, Lipid and RNA components, and emerging targets to support pipeline expansion. * Assist ...
Receptionist / Administrative Assistant
Newark, DE ยท On-site
$19 - $20/hr
Life
Retirement
... DMPK, Toxicology, Bioanalysis, Translational Medicine, Early Phase Clinical and Phase II - IV ... The Job * Greet and assist visitors, employees, vendors, and callers in a professional and ...
New
Quick apply
Receptionist / Administrative Assistant
Newark, DE ยท On-site
$19 - $20/hr
Life
Retirement
... DMPK, Toxicology, Bioanalysis, Translational Medicine, Early Phase Clinical and Phase II - IV ... The Job * Greet and assist visitors, employees, vendors, and callers in a professional and ...
New
Product Scientist
New York, NY ยท On-site
$180K - $220K/yr
Medical
Dental
Vision
... assistant. Through a partnership with Enamine, we also offer library synthesis and direct-to-dose ... and DMPK expertise to real molecular optimization problems with a focus on dose-centric ...
Product Scientist
New York, NY ยท On-site
$180K - $220K/yr
Medical
Dental
Vision
... assistant. Through a partnership with Enamine, we also offer library synthesis and direct-to-dose ... and DMPK expertise to real molecular optimization problems with a focus on dose-centric ...
Scientific Business Analyst
South San Francisco, CA ยท On-site
$75/hr
... applications. * Assist with post-implementation activities, including validation efforts, issue ... Familiarity with medicinal chemistry, analytical chemistry, DMPK, and/or biochemical and cellular ...
Scientific Business Analyst
South San Francisco, CA ยท On-site
$75/hr
... applications. * Assist with post-implementation activities, including validation efforts, issue ... Familiarity with medicinal chemistry, analytical chemistry, DMPK, and/or biochemical and cellular ...
Research Assistant II - ADME In Vitro Screening
Madison, WI ยท On-site
Medical
Dental
Vision
Life
Retirement
PTO
Labcorp is seeking a Research Assistant II - ADME In Vitro Screening to join our team in Madison ... work, or DMPK assays. Additional Job Standards: * Consistently and continuously responds ...
Research Assistant II - ADME In Vitro Screening
Madison, WI ยท On-site
Medical
Dental
Vision
Life
Retirement
PTO
Labcorp is seeking a Research Assistant II - ADME In Vitro Screening to join our team in Madison ... work, or DMPK assays. Additional Job Standards: * Consistently and continuously responds ...
Research Assistant II - ADME In Vitro Screening
Madison, WI ยท On-site
Medical
Dental
Vision
Life
Retirement
PTO
Labcorp is seeking a Research Assistant II - ADME In Vitro Screening to join our team in Madison ... work, or DMPK assays. Additional Job Standards: * Consistently and continuously responds ...
Research Assistant II - ADME In Vitro Screening
Madison, WI ยท On-site
Medical
Dental
Vision
Life
Retirement
PTO
Labcorp is seeking a Research Assistant II - ADME In Vitro Screening to join our team in Madison ... work, or DMPK assays. Additional Job Standards: * Consistently and continuously responds ...
Research Assistant II - ADME In Vitro Screening
Medical
Dental
Vision
Life
Retirement
PTO
Labcorp is seeking a Research Assistant II - ADME In Vitro Screening to join our team in Madison ... work, or DMPK assays. Additional Job Standards: * Consistently and continuously responds ...
Research Assistant II - ADME In Vitro Screening
Medical
Dental
Vision
Life
Retirement
PTO
Labcorp is seeking a Research Assistant II - ADME In Vitro Screening to join our team in Madison ... work, or DMPK assays. Additional Job Standards: * Consistently and continuously responds ...
Research Assistant II - ADME In Vitro Screening
Medical
Dental
Vision
Life
Retirement
PTO
Labcorp is seeking a Research Assistant II - ADME In Vitro Screening to join our team in Madison ... work, or DMPK assays. Additional Job Standards: * Consistently and continuously responds ...
Research Assistant II - ADME In Vitro Screening
Medical
Dental
Vision
Life
Retirement
PTO
Labcorp is seeking a Research Assistant II - ADME In Vitro Screening to join our team in Madison ... work, or DMPK assays. Additional Job Standards: * Consistently and continuously responds ...
Specialist, QuickBase Administration
Newark, DE ยท On-site
Life
Retirement
... DMPK, Toxicology, Bioanalysis, Translational Medicine, Early Phase Clinical and Phase II - IV ... Manage and implement database security and user accounts. * Assist with the design and development ...
Quick apply
Specialist, QuickBase Administration
Newark, DE ยท On-site
Life
Retirement
... DMPK, Toxicology, Bioanalysis, Translational Medicine, Early Phase Clinical and Phase II - IV ... Manage and implement database security and user accounts. * Assist with the design and development ...
PRN Logistics Technician
Springfield, MO ยท On-site
$18 - $22.50/hr
... DMPK, Toxicology, Bioanalysis, Translational Medicine, Early Stage Clinical and Phase I IV Clinical ... Monitor inventory levels and assist with ordering laboratory and operational supplies * Assemble ...
New
Quick apply
PRN Logistics Technician
Springfield, MO ยท On-site
$18 - $22.50/hr
... DMPK, Toxicology, Bioanalysis, Translational Medicine, Early Stage Clinical and Phase I IV Clinical ... Monitor inventory levels and assist with ordering laboratory and operational supplies * Assemble ...
New
Lab Technician
Exton, PA ยท On-site
$18.25 - $24.25/hr
Medical
Dental
Life
Retirement
... DMPK), pharmacodynamics (PD), bioanalytical services, safety and toxicology, Chemistry ... * Assist with sample receipt, logging, labeling, storage, retrieval, and chain-of-custody ...
Quick apply
Lab Technician
Exton, PA ยท On-site
$18.25 - $24.25/hr
Medical
Dental
Life
Retirement
... DMPK), pharmacodynamics (PD), bioanalytical services, safety and toxicology, Chemistry ... * Assist with sample receipt, logging, labeling, storage, retrieval, and chain-of-custody ...
... contracting. Assist with RFx creation, analysis, and vendor presentations (Bid defenses ... such as Chemistry, DMPK, PK/PD, RNA/DNA Sequencing, Bioinformatics, In-Vivo Toxicology ...
Quick apply
... contracting. Assist with RFx creation, analysis, and vendor presentations (Bid defenses ... such as Chemistry, DMPK, PK/PD, RNA/DNA Sequencing, Bioinformatics, In-Vivo Toxicology ...
VP, Toxicology
San Francisco, CA ยท Remote
Define target safety profiles and guide compound progression decisions in partnership with Discovery, DMPK, Clinical Pharmacology, and Clinical Development teams. Study Design & Execution * Design ...
Quick apply
VP, Toxicology
San Francisco, CA ยท Remote
Define target safety profiles and guide compound progression decisions in partnership with Discovery, DMPK, Clinical Pharmacology, and Clinical Development teams. Study Design & Execution * Design ...
VP, Toxicology
San Francisco, CA ยท On-site
$310K - $340K/yr
Define target safety profiles and guide compound progression decisions in partnership with Discovery, DMPK, Clinical Pharmacology, and Clinical Development teams. Study Design & Execution * Design ...
VP, Toxicology
San Francisco, CA ยท On-site
$310K - $340K/yr
Define target safety profiles and guide compound progression decisions in partnership with Discovery, DMPK, Clinical Pharmacology, and Clinical Development teams. Study Design & Execution * Design ...
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Job description
Position Overview
We are seeking an enthusiastic, self-motivated Senior Scientist to join the Nonclinical Development group, supporting the nonclinical safety assessment function for IND-enabling programs across Prime Medicine's pipeline. Reporting to the Associate Director, Safety Assessment, the successful candidate will support the design, execution, and interpretation of nonclinical safety studies conducted both in-house and at CROs, with an initial focus on liver-targeted therapeutics. This role requires hands-on involvement in assay execution and troubleshooting, as well as active participation in study oversight of work being done at CRO and data analysis.
This role requires collaboration within cross-functional teams. The ideal candidate will hold a Ph.D. in toxicology or a related field with 6+ years of pharma/biotech experience in nonclinical safety assessment, or an M.S. in toxicology or a related field with 10+ years of experience in nonclinical safety assessment, the ability to work independently, provide domain expertise and leadership, as well as cross-functionally in a fast-paced, matrixed environment with a positive, flexible attitude. ย ย
Primary Responsibilities
- Contribute to nonclinical safety activities as part of cross-functional Discovery and Development project teams, supporting program progression through IND-enabling stages.
- Design, execute, and troubleshoot nonclinical safety studies, including hands-on laboratory work (~30%) to support assay development, data generation, and issue resolution.
- Support the execution and oversight of nonclinical safety studies (GLP and non-GLP) at CROs, including active involvement in troubleshooting assay and study-related challenges.
- Analyze and interpret study data with guidance and contribute to the preparation of study reports and supporting documents for regulatory submissions.
- Collaborate with Pharmacology, DMPK, and other functions to support exploratory studies (e.g., exploratory toxicology, DMPK, biodistribution, and delivery platform evaluation).
- Contribute to evaluation of new delivery approaches, Lipid and RNA components, and emerging targets to support pipeline expansion.
- Assist in identifying potential safety findings and contribute to discussions on data interpretation and next steps.
- Ensure studies and internal activities are conducted in compliance with regulatory guidelines and internal standards.
Preferred Qualifications
- Ph.D. in toxicology or a related discipline with 6+ years of biopharmaceutical industry experience, or M.S. in toxicology or a related field with 10+ years of relevant biopharmaceutical industry experience supporting drug development in nonclinical safety/toxicology.
- Experience in large molecule therapeutic development, along with a background in immunology, is desirable.
- Understanding of toxicology principles, nonclinical safety evaluation, and the drug development process, with some experience interpreting toxicology data and contributing to technical and scientific reports.
- Demonstrates strong scientific judgment and leadership with the ability to evaluate information, identify potential issues, and propose practical solutions with guidance as needed.
- Highly organized and detail-oriented with strong attention to accuracy and quality.
- Strong communication and collaboration skills, with the ability to work effectively across multidisciplinary teams and with external partners.
- Experience supporting nonclinical studies at CROs is preferred but not required.
About Prime Medicine
Sourced by ZipRecruiter
Industry
Biotechnology research and development
Company size
51 - 200 Employees
Headquarters location
Cambridge, MA, US
Year founded
2019