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Assay Development Scientist Jobs (NOW HIRING)

GENERAL FLUIDICS CORPORATION

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Director of Assay Development

Watertown, MA · On-site

Experience supporting product development within clinical diagnostics, including assay development ... Strong experimental design, laboratory troubleshooting, and scientific data analysis skills.

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How much do assay development scientist jobs pay per hour?

As of Jul 7, 2026, the average hourly pay for assay development scientist in the United States is $38.66, according to ZipRecruiter salary data. Most workers in this role earn between $28.37 and $46.15 per hour, depending on experience, location, and employer.

What is an Assay Development Scientist job?

An Assay Development Scientist designs, optimizes, and validates biochemical and cell-based assays for drug discovery, diagnostics, or research applications. They work with a variety of techniques such as ELISA, PCR, and high-throughput screening to measure biological or chemical responses. Their role involves troubleshooting, data analysis, and collaboration with cross-functional teams to ensure assay accuracy and reproducibility.

What are the key skills and qualifications needed to thrive in the Assay Development Scientist position, and why are they important?

To thrive as an Assay Development Scientist, you need a strong background in biochemistry, molecular biology, or a related field, along with experience in assay design, optimization, and validation. Proficiency with laboratory instrumentation such as plate readers, liquid handlers, and data analysis software (e.g., GraphPad Prism or SoftMax Pro), as well as familiarity with regulatory guidelines, is often required. Effective problem-solving, meticulous attention to detail, and strong communication skills set exceptional candidates apart. These abilities ensure the successful development of reliable assays, facilitate collaboration with interdisciplinary teams, and support impactful scientific advancements.

What does a typical day look like for an Assay Development Scientist?

A typical day for an Assay Development Scientist involves designing experiments, running and optimizing biochemical or cell-based assays, analyzing data, and documenting results. You will often collaborate closely with cross-functional teams, including research scientists, project managers, and quality assurance specialists, to ensure assays meet project requirements. Regular meetings to discuss progress, troubleshoot technical challenges, and plan next steps are common. The role also involves staying up-to-date with new technologies and industry standards to continuously improve assay performance.

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Assay Development Scientist jobs near you
Senior Research Associate- Diagnostic Assay Development

Senior Research Associate- Diagnostic Assay Development

10x Genomics

Pleasanton, CA • On-site

Other

Posted 19 days ago

Job description

About the Role:

10x Genomics is establishing a diagnostics effort, translating our leading single cell and spatial assay technologies into impactful clinical applications. We are seeking a highly skilled and motivated Senior Research Associate to join the Diagnostic Assay Development team. The SRA will be a key contributor, executing the technical development, optimization, and rigorous testing of novel Laboratory Developed Tests (LDTs) in a dynamic, high-growth environment. This role, reporting to the Sr. Manager, Diagnostic Assay Development, requires extensive hands-on experience in advanced molecular biology techniques and a dedication to high-quality data generation in support of ambitious product development goals.

What you will be doing:

Assay Execution and Optimization
  • Hands-on execution of complex single-cell and spatial genomics assays (e.g., sample processing, library preparation, sequencing).
  • Systematically troubleshoot, optimize, and refine specific steps within the assay workflow to improve performance, robustness, and efficiency.
  • Perform feasibility studies on new reagents, instrumentation, and process improvements for clinical readiness.
  • Prepare and process samples in support of large-scale clinical research studies
Documentation and Analytical Studies
  • Generate and maintain meticulous laboratory records, protocols (SOPs), and batch records following Good Documentation Practices (GDP).
  • Execute formal experiments for analytical validation studies, including assessment of accuracy, precision, limit of detection, and reproducibility.
  • Ensure all work is conducted under appropriate quality controls
  • Present experimental data clearly and concisely in team meetings and written reports.
Cross-Functional Collaboration
  • Support the transfer of robust assay workflows to the CLIA operations team.
  • Collaborate closely with R&D Scientists, Automation Engineers, and Bioinformatics teams to meet project milestones.
  • Work closely with the internal lab operations team to support the maintenance of a high-quality, organized laboratory environment, including inventory management and forecasting, equipment calibration, and ensuring compliance with safety standards.
Minimum Requirements:
  • B.S. or M.S. in Molecular Biology, Genetics, Biochemistry, or a related scientific field.
  • B.S. with 5+ years or M.S. with 3+ years of hands-on experience in molecular diagnostics or genomics assay development in an industry setting.
  • Direct, demonstrable experience with advanced molecular technologies, particularly Next-Generation Sequencing (NGS) workflows
  • Exceptional proficiency in molecular biology techniques, including nucleic acid extraction, PCR/qPCR, and NGS library preparation
  • A proven track-record of using and optimizing and troubleshooting molecular biology protocols.
  • Experience working with challenging clinical sample types (e.g., FFPE tissue, primary tumor cells, low-input samples).
  • Experience working within a quality system or environment governed by CLIA, CAP, or ISO 13485 standards strongly preferred.
  • Prior hands-on experience with 10x Genomics single-cell or spatial technologies (e.g., Chromium or Xenium platforms) is a strong advantage.
  • Experience with automated liquid handling for high-throughput assay execution is a strong advantage; experience with microscopy techniques a plus
Preferred Skills & Experience:
  • Ability to organize, analyze, and interpret complex data sets (e.g., assay metrics, quality control data) and effectively troubleshoot issues based on results.
  • Commitment to rigorous execution, meticulous record-keeping, and high standards of scientific quality.
  • Possess excellent communication skills, and can effectively collaborate with interdisciplinary teams, integrating their feedback into your experimental design.
  • Thrive in fast-paced environments, and excel at managing multiple priorities, adapting to change, and consistently delivering results.

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