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Antibody Engineering Jobs (NOW HIRING)

Washington University of St. Louis

Our laboratory develops next-generation antibody-drug conjugates (ADCs), molecular imaging agents, and targeted therapeutics to improve cancer diagnosis and treatment. We combine protein engineering ...

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How much do antibody engineering jobs pay per hour?

As of Aug 22, 2026, the average hourly pay for antibody engineering in the United States is $33.06, according to ZipRecruiter salary data. Most workers in this role earn between $26.44 and $38.22 per hour, depending on experience, location, and employer.

What is an antibody engineering job?

An Antibody Engineering job involves designing, modifying, and optimizing antibodies for therapeutic, diagnostic, or research applications. Professionals in this field use techniques such as protein engineering, phage display, and computational modeling to enhance antibody specificity, stability, and efficacy. They work in biotechnology, pharmaceutical, or academic settings to develop novel treatments for diseases like cancer, autoimmune disorders, and infectious diseases. This role requires expertise in molecular biology, immunology, and bioinformatics.

What does a typical day look like for someone working in antibody engineering?

A typical day in Antibody Engineering involves designing and generating antibody variants in the lab, analyzing experimental data, and collaborating with multidisciplinary teams such as bioinformatics, cell biology, and process development. You may participate in regular meetings to discuss project progress, troubleshoot experiments, and optimize methodologies. Much of the work is hands-on and fast-paced, with deadlines tied to ongoing research projects or product development timelines. This role offers a dynamic environment where continuous learning and innovation are highly encouraged.

What are the key skills and qualifications needed to thrive in antibody engineering, and why are they important?

To thrive in Antibody Engineering, you need a strong background in molecular biology, biochemistry, and protein engineering, typically supported by an advanced degree in a related field. Experience with molecular cloning techniques, high-throughput screening platforms, and data analysis software such as Python or R is highly valuable. Strong problem-solving abilities, attention to detail, and effective teamwork skills set top candidates apart. These competencies enable successful design and optimization of antibodies, critical for therapeutic and diagnostic applications.

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Antibody Engineering jobs near you
Infographic showing various Antibody Engineering job openings in the United States as of August 2026, with employment types broken down into 92% Full Time, 4% Part Time, 3% Contract, and 1% Nights. Highlights an 85% Physical, 5% Hybrid, and 10% Remote job distribution, with an average salary of $68,760 per year, or $33.1 per hour.

Senior Scientist, Antibody Engineering & Discovery (BMD)

Pfizer

San Diego, CA • On-site

$93K - $156K/yr

Full-time

Medical, Dental, Vision, Retirement, PTO

This job post has expired 1 day ago. Applications are no longer accepted.

Pfizer rating

8.2

Company rating: 8.2 out of 10

Based on 125 frontline employees who took The Breakroom Quiz

32nd of 86 rated pharmaceutical

Job description

Role Overview

The BioMedicine Design (BMD) group at Pfizer Torrey Heights site is seeking a highly motivated Senior Scientist (R4) to contribute to the discovery and engineering of next-generation biologics, with an emphasis on multispecific antibodies like immune cell engagers (TCEs).

This role will leverage yeast and phage display platforms to drive antibody discovery and optimization and will contribute to format engineering across immuno-oncology portfolios. A successful candidate will bring strong scientific rigor, execution excellence, and a collaborative mindset to advance programs from early discovery through candidate selection, delivering high-quality molecules for challenging targets. The candidate will have access to state-of-the-art protein and antibody engineering technologies and will be expected to continue our tradition of developing world-class methods and technologies that enhance our therapeutic discovery efforts.

Key Responsibilities

  • Design and execute antibody discovery/engineering campaigns using yeast/phage display technologies, including library construction, screening, and hit identification
  • Implement innovative strategies for the design and development of next-generation multispecific biologics
  • Leverage cross-functional data to define and drive molecular design and optimization strategies, collaborate across internal teams and external partners to drive efficient decision-making and program advancement
  • Contribute to platform development and continuous improvement of display technologies and screening strategies
  • Clearly communicate results and scientific insights to project teams and leadership
  • Stay informed with literature and scientific advancement in the biologics discovery and engineering field
  • Maintain rigorous documentation and uphold high standards of scientific quality and data integrity

Basic Qualifications

  • Ph.D. in Immunology, Molecular Biology, Protein Engineering, Chemical and Biomolecular Engineering or a related field, with postdoctoral training
  • Demonstrated strong hands-on expertise in yeast display for antibody discovery and/or engineering, with creative problem-solving and solid analytical skills.
  • Extensive technical skills in protein expression, purification and molecular biology.
  • Strong publication record in peer-reviewed journals, reflecting scientific innovation and impact
  • Proven ability to independently design experiments, analyze complex datasets, and drive scientific decisions
  • Excellent work ethic, with strong ownership, attention to detail, and a commitment to high-quality execution

Preferred Qualifications

  • Demonstrated experience in project leadership within cross-functional teams
  • Proven expertise in multispecific antibody design and production, including format engineering and expression strategies
  • Working knowledge of computational tools supporting antibody discovery and engineering workflows
  • Prior experience in a matrixed drug discovery environment, ideally in biologics or antibody therapeutics

Key Attributes

  • Strong scientific curiosity and problem-solving mindset
  • Ability to operate effectively in a fast-paced, collaborative environment
  • Clear and concise communication skills, with the ability to influence cross-functional decisions
  • Commitment to BMD culture: collaboration, scientific excellence, and delivery for portfolio impact ("we better")


Work location assignment: On Premise.

The annual base salary for this position ranges from $93,600.00 to $156,000.00. In addition, this position is eligible for participation in Pfizer's Global Performance Plan with a bonus target of 12.5% of the base salary and eligibility to participate in our share based long term incentive program. We offer comprehensive and generous benefits and programs to help our colleagues lead healthy lives and to support each of life's moments. Benefits offered include a 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution, paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage. Learn more at Pfizer Candidate Site - U.S. Benefits | (uscandidates.mypfizerbenefits.com). Pfizer compensation structures and benefit packages are aligned based on the location of hire. The United States salary range provided does not apply to Tampa, FL or any location outside of the United States.

Relocation assistance may be available based on business needs and/or eligibility.

Candidates must be authorized to be employed in the U.S. by any employer.

U.S. work visa sponsorship (such as TN, O-1, H-1B, etc.) is not available for this role now or in the future.

Sunshine Act

Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care provider's name, address and the type of payments or other value received, generally for public disclosure. Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government. If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative.

EEO & Employment Eligibility

Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer. This position requires permanent work authorization in the United States.

Pfizer endeavors to makewww.pfizer.com/careersaccessible to all users. If you would like to contact us regarding the accessibility of our website or need assistance completing the application process and/or interviewing, please emaildisabilityrecruitment@pfizer.com. This is to be used solely for accommodation requests with respect to the accessibility of our website, online application process and/or interviewing. Requests for any other reason will not be returned.

To learn more about acceptable and prohibited uses of AI during the recruitment process, please review our candidate AI-use guidelines available onPfizer Careers.

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About Pfizer

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All over the world, Pfizer colleagues work together to positively impact health for everyone, everywhere. Our colleagues have the opportunity to grow and develop a career that offers both individual and company success; be part of an ownership culture that values diversity and where all colleagues are energized and engaged; and the ability to impact the health and lives of millions of people. Pfizer, a global leader in the biopharmaceutical industry, is continuously seeking top talent who are inspired by our purpose to innovate to bring therapies to patients that significantly improve their lives. Our Health and Science System Specialists Team provides leadership across patient care settings in the complex Hospital, Health System, and Key Medical Group environment to bring value to our customers and patients in this dynamic ecosystem.

Industry

Pharmaceutical and medicine manufacturing

Company size

10,000+ Employees

Headquarters location

New York, NY, US

Year founded

1849

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