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Antibody Engineering Postdoc Jobs (NOW HIRING)

Saint Louis University

Post Doctoral Fellow

Saint Louis, MO · On-site

$47K - $64K/yr

... antibody enhancement. Unwanted/unsafe epitopes will be removed via viral engineering. Research ... This is a full-time Postdoctoral Researcher role at Saint Louis University. What can the Tse lab ...

Saint Louis University

Post Doctoral Fellow

Saint Louis, MO

$47K - $64K/yr

... antibody enhancement. Unwanted/unsafe epitopes will be removed via viral engineering. Research ... This is a full-time Postdoctoral Researcher role at Saint Louis University. What can the Tse lab ...

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All JobsAntibody Engineering Postdoc Jobs

Antibody Engineering Postdoc information

See salary details

$34.5K

$111.2K

$183K

How much do antibody engineering postdoc jobs pay per year?

As of Jun 9, 2026, the average yearly pay for antibody engineering postdoc in the United States is $111,182.00, according to ZipRecruiter salary data. Most workers in this role earn between $77,000.00 and $144,000.00 per year, depending on experience, location, and employer.

What are some common challenges faced by Antibody Engineering Postdocs when optimizing antibody affinity and specificity?

Antibody Engineering Postdocs often encounter challenges balancing affinity improvement with maintaining specificity, as enhancing one property can inadvertently compromise the other. Additionally, experimental hurdles such as expression yield, stability, and solubility of engineered antibodies require careful troubleshooting. Collaboration with structural biologists, biochemists, and computational modelers is typically essential to interpret results and iterate designs effectively. Being adaptable and open to interdisciplinary feedback is key to overcoming these complex challenges.

What are Antibody Engineering Postdocs?

Antibody Engineering Postdocs are researchers who have completed their doctoral studies and are engaged in advanced research focused on designing, modifying, and optimizing antibodies for various applications. Their work often involves molecular biology, protein engineering, and immunology to develop antibodies with improved specificity, affinity, or therapeutic potential. These postdoctoral scientists typically work in academic, biotech, or pharmaceutical settings, contributing to projects such as drug discovery, diagnostics, or understanding immune responses. The position is highly collaborative and may include publishing research, mentoring students, and presenting findings at conferences.

What are the key skills and qualifications needed to thrive as an Antibody Engineering Postdoc, and why are they important?

To thrive as an Antibody Engineering Postdoc, you need a PhD in molecular biology, biochemistry, or a related field, with expertise in protein engineering and antibody design. Experience with techniques such as phage display, flow cytometry, and bioinformatics tools, as well as familiarity with relevant laboratory software, is crucial. Strong problem-solving abilities, attention to detail, and effective collaboration and communication skills help you excel in multidisciplinary research environments. These competencies are essential for advancing innovative antibody therapeutics and contributing meaningful scientific discoveries.

What is the difference between Antibody Engineering Postdoc vs Antibody Development Scientist?

AspectAntibody Engineering PostdocAntibody Development Scientist
Required CredentialsPhD in immunology, molecular biology, or related fieldBachelor's or Master's in related sciences, with experience in antibody development
Work EnvironmentAcademic or research institutions, laboratoriesBiotech or pharmaceutical industry, R&D labs
Employer & Industry UsagePrimarily academia, research institutesIndustry-focused, product development companies
Common Search & Comparison IntentUnderstanding research-focused roles in antibody engineeringRoles involved in antibody development and production

While both roles involve working with antibodies, the Antibody Engineering Postdoc is primarily research-oriented, focusing on developing new antibody technologies in academic or research settings. In contrast, the Antibody Development Scientist typically works in industry, focusing on the development, optimization, and production of antibody-based therapeutics or diagnostics.

Infographic showing various Antibody Engineering Postdoc job openings in the United States as of June 2026, with employment types broken down into 100% Full Time. Highlights an 100% In-person job distribution, with an average salary of $111,182 per year, or $53.5 per hour.
Postdoctoral Scholar, Immunogenicity

Postdoctoral Scholar, Immunogenicity

Johnson and Johnson

Reading, PA • On-site

$39K - $52K/yr

Full-time

This job post has expired 1 day ago. Applications are no longer accepted.

Job description

At Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity. Learn more at jnj.com.
As guided by Our Credo, Johnson & Johnson is responsible to our employees who work with us throughout the world. We provide an inclusive work environment where each person is considered as an individual. At Johnson & Johnson, we respect the diversity and dignity of our employees and recognize their merit.
Job Function:
Career Programs
Job Sub Function:
Post Doc - R&D Product Development
Job Category:
Career Program
All Job Posting Locations:
Spring House, Pennsylvania, United States of America
Job Description:
About Innovative Medicine
Our expertise in Innovative Medicine is informed and inspired by patients, whose insights fuel our science-based advancements. Visionaries like you work on teams that save lives by developing the medicines of tomorrow.
Join us in developing treatments, finding cures, and pioneering the path from lab to life while championing patients every step of the way.
Learn more at https://www.jnj.com/innovative-medicine
We are searching for the best talent for a Postdoctoral Scholar, Immunogenicity to be located in Spring House, PA.
Purpose: A current gap exists in the ability of preclinical models to accurately predict clinical immunogenicity and anti-drug antibody (ADA) rates and its impact (e.g., safety and efficacy) on therapeutic biologics. Bioanalytical Discovery & Development Sciences (BDDS) department within the Preclinical Sciences & Translational Safety (PSTS) organization at Johnson &Johnson is seeking a postdoctoral scholar to develop and scientifically validate in vitro and immune organoid models for preclinical immunogenicity assessment of therapeutic biologics. To pair with data generated by in vitro models, the postdoc will work with colleagues to develop a database to aid in immunogenicity assessment via reverse engineering through comprehensive drug-specific datasets. Successful development of these novel immunogenicity tools will aid in the identification and development of safer and more efficacious biologics.
In this position, the postdoctoral scholar will lead assay development and optimization of novel in vitro immunogenicity models, demonstrate proof of concept of in vitro immunogenicity models, and author SOPs. The postdoc will work cross-functionally with colleagues from PSTS, clinical pharmacology, discovery, translational safety, and other relevant organizations to enable broader adoption of in vitro tools (in vitro and bioinformatic) as part of the preclinical development strategy.
You will be responsible for:
  • Leading the design, development, and optimization of in vitro models enabling immunogenicity assessments of therapeutic biologics (e.g., MAPPs, immune organoids, organ-on-a-chip, etc).
  • Collaborating with cross-functional teams (PSTS, clinical pharmacology, discovery, data sciences, translational science, and external partners) to build a comprehensive drug-specific database.
  • Attending technical seminars, workshops, or conferences for improving practical or technical knowledge and enabling completion of project objectives.
  • Producing and maintaining clear technical documentation, including electronic notebooks and SOPs to support reproducibility and technology dissemination.
  • Communicating findings through written reports, presentations, and contributions to manuscripts.
Qualifications/Requirements
Education:
  • A PhD in Immunology, Bioengineering, Immuno-Oncology, or a related field is required.
Experience and Skills:
Required:
  • Hands-on experience developing and optimizing immunoassays (e.g., ELISA, ELISpot/FluoroSpot, Flow Cytometry, or related) measuring immune responses is required.
  • Primary immune cell culture experience: short- and long-term mammalian immune cell culture, primary immune cell isolation from tissue or primary fluids (e.g. whole blood, cerebrospinal fluid), and primary immune cell differentiation is required.
  • Demonstrated record of immunology-related publications is required.
  • Excellent written and verbal communication skills; ability to work in cross-functional teams and present technical results to diverse audiences is required.
  • Strong interpersonal & collaborative skills with an ability to operate as part of a team in a highly interdependent environment is required.
  • Must be adaptable, responsive, and committed to completing tasks in a timely fashion.
Preferred:
  • Experience with 3D cell culture systems such as but not limited to organoids and/or organ-on-a-chip is preferred.
  • Experience developing or conducting in vitro vaccination and/or in vitro PBMC expansion assays is preferred.
  • Familiarity with bioanalytical platforms for ultrasensitive detection and an understanding of their strengths/limitations such as LC/MS and Immunopeptidomics is preferred.

Other:
  • This role may require up to 10% travel a needed.

Johnson & Johnson is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, age, national origin, disability, protected veteran status or other characteristics protected by federal, state or local law. We actively seek qualified candidates who are protected veterans and individuals with disabilities as defined under VEVRAA and Section 503 of the Rehabilitation Act.
Johnson & Johnson is committed to providing an interview process that is inclusive of our applicants' needs. If you are an individual with a disability and would like to request an accommodation, external applicants please contact us via https://www.jnj.com/contact-us/careers, internal employees contact AskGS to be directed to your accommodation resource.
#LI-Onsite
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Preferred Skills:

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