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Protein Purification Postdoc Jobs (NOW HIRING)

Ohio State University

Postdoc Scholar

Columbus, OH · On-site

Postdoc Scholar A laboratory offering state-of-the-art equipment and core facilities within the ... purification for studying protein-protein interactions, cell culture, and use of advanced ...

Ohio State University

Postdoc Scholar

Columbus, OH · On-site

Postdoc Scholar A laboratory offering state-of-the-art equipment and core facilities within the ... purification for studying protein-protein interactions, cell culture, and use of advanced ...

Ohio State University

Postdoc Scholar

Columbus, OH · On-site

## Postdoc ScholarApplylocations: Columbus Campustime type: Full timeposted on: Posted Todayjob ... purification for studying protein-protein interactions, cell culture, and use of advanced ...

Tamus

Postdoctoral Research Associate

Bryan, TX · On-site

Job Title Postdoctoral Research Associate Agency Texas A&M University Health Science Center ... Experience in protein expression and purification and in biochemical characterization of proteins ...

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Protein Purification Postdoc information

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How much do protein purification postdoc jobs pay per hour?

As of Sep 12, 2026, the average hourly pay for protein purification postdoc in the United States is $29.64, according to ZipRecruiter salary data. Most workers in this role earn between $26.68 and $32.69 per hour, depending on experience, location, and employer.

What is a protein purification postdoc?

Protein Purification Postdocs are researchers who have completed their doctoral studies and are engaged in advanced training and research focused on isolating and purifying proteins from various sources. Their work typically involves designing and optimizing purification protocols, analyzing protein structure and function, and supporting broader biochemical or biomedical research projects. They often use techniques such as chromatography, electrophoresis, and affinity tagging. These postdoctoral researchers play a key role in advancing scientific understanding of proteins and developing applications in fields like medicine, biotechnology, and pharmaceuticals.

What are some common challenges faced by protein purification postdocs when scaling up protocols from research to production levels?

Protein Purification Postdocs often encounter challenges when translating small-scale laboratory protocols to larger-scale production, including maintaining protein stability, optimizing yield, and ensuring reproducibility. Differences in buffer composition, equipment limitations, and increased risk of protein degradation can complicate the process. Collaborating closely with upstream (expression) and downstream (analytical) teams is crucial for troubleshooting and achieving consistent results. Gaining experience with a variety of purification systems and techniques can help overcome these challenges and broaden career opportunities in both academia and industry.

What are the key skills and qualifications needed to thrive as a protein purification postdoc, and why are they important?

To thrive as a Protein Purification Postdoc, you need advanced knowledge in biochemistry, molecular biology, and protein chemistry, typically supported by a PhD in a related field. Experience with protein purification systems (such as FPLC and HPLC), analytical techniques (SDS-PAGE, Western blot), and relevant software is essential. Strong problem-solving abilities, meticulous attention to detail, and effective communication skills set outstanding candidates apart. These competencies ensure the efficient isolation and characterization of proteins, which is crucial for high-quality research outcomes.

What are popular job titles related to Protein Purification Postdoc jobs?

For Protein Purification Postdoc jobs, the most frequently searched job titles are:

Infographic showing various Protein Purification Postdoc job openings in the United States as of September 2026, with employment types broken down into 82% Full Time, 14% Part Time, 3% Contract, and 1% Nights. Highlights an 89% Physical, 1% Hybrid, and 10% Remote job distribution, with an average salary of $61,648 per year, or $29.6 per hour.

Scientist/Sr Scientist - Protein Production and Purification

Palo Alto, CA • On-site

Kodiak Sciences Inc
Biotechnology Research and Development • 11 - 50 employees
Learn more about Kodiak Sciences Incexternal

Full-time

This job post has expired today. Applications are no longer accepted.

Job description

Description
Kodiak Sciences Inc. is a fast-growing, clinical-stage biopharmaceutical company focused on transforming ophthalmology through innovative therapeutics. Our Antibody Biopolymer Conjugate Drug (ABCD) platform combines protein engineering, polymer chemistry, small molecule drug discovery, bioconjugation, and drug delivery to address high-prevalence ophthalmic diseases.
We are seeking a motivated and independent Protein Production Scientist/Sr. Scientist to join our Discovery Medicine group as part of the Protein Engineering team. The successful candidate will be an outstanding scientist with demonstrated expertise in recombinant protein expression and purification and will play a central role in advancing our discovery and research programs. This individual will excel at developing and executing robust protein production strategies, delivering high-quality recombinant proteins that enable antibody engineering, biochemical characterization, and functional evaluation. This is an exciting opportunity to contribute to the development of innovative therapeutics within a collaborative, fast-paced, and interdisciplinary research environment.
Responsibilities
  • Design, execute, and optimize recombinant protein expression workflows for a broad range of recombinant protein targets, including antibodies, therapeutic proteins, enzymes, and research reagents, using transient mammalian expression systems (e.g., HEK293, CHO) and bacterial expression platforms.
  • Develop, optimize, and execute purification processes for diverse recombinant proteins using affinity, ion exchange, size exclusion, and other chromatographic techniques.
  • Purify protein conjugates, including protein-polymer and protein-drug conjugates, by applying established methodologies and developing innovative purification strategies to address complex molecular formats.
  • Perform biochemical and biophysical characterization of recombinant proteins using SDS-PAGE, SEC, DLS, mass photometry, isoelectric focusing (IEF), and complementary analytical techniques to evaluate protein quality, purity, identity, aggregation, stability, and other critical quality attributes.
  • Maintain, optimize, and troubleshoot mammalian cell culture and recombinant protein production processes to ensure robust, reproducible expression and high-quality protein yields.
  • Plan, prioritize, and coordinate protein production activities across multiple research programs to meet project objectives and timelines.
  • Analyze and interpret experimental data, prepare technical reports, and present scientific findings and recommendations to cross-functional project teams.
  • Maintain comprehensive laboratory notebooks, experimental records, and protein inventory databases to ensure data integrity, traceability, regulatory compliance, and efficient sample management.
  • Independently manage laboratory operations, maintain equipment and reagent inventories, and drive continuous improvement initiatives to enhance protein production, purification, and analytical workflows.

Education & Qualifications
  • Ph.D. in Biochemistry, Cell Biology, Molecular Biology, Protein Science, or a related discipline with 0-5 years of relevant postdoctoral and/or industry experience; or M.S. or B.S. in related discipline with 5+ years of relevant industry experience.
  • Demonstrated expertise in recombinant protein expression using transient mammalian expression systems (e.g., HEK293, CHO); experience with bacterial expression systems is preferred.
  • Extensive hands-on experience in the purification of antibodies and diverse recombinant proteins using affinity, ion exchange, size exclusion, and other chromatographic techniques in both column- and batch-based formats.
  • Proficiency in operating, optimizing and troubleshooting protein purification platforms, including ÄKTA FPLC systems; experience with KingFisher or other automated purification platforms is highly desirable.
  • Strong foundation in protein biochemistry and hands-on experience with biochemical and biophysical characterization techniques, including SDS-PAGE, SEC, DLS, UV-Vis spectroscopy, mass photometry, isoelectric focusing (IEF), and related analytical methods.
  • Demonstrated ability to independently design, execute, optimize, troubleshoot, and interpret recombinant protein expression, purification, and characterization experiments.
  • Proven ability to optimize protein production workflows and implement innovative approaches to improve productivity, protein quality, and throughput.
  • Excellent organization skills, meticulous attention to detail, and commitment to maintaining accurate experimental records and documentation.
  • Strong written and verbal communication skills, with the ability to effectively collaborate and communicate scientific findings across multidisciplinary research teams.

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