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Protein Purification Postdoc Jobs (NOW HIRING)

NJ · On-site

Semenova, the postdoctoral fellow will participate in grant-funded research aimed at characterizing ... RNA purification and analysis, and protein-nucleic acid interactions is required. The candidate ...

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Protein Purification Postdoc information

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How much do protein purification postdoc jobs pay per hour?

As of Sep 13, 2026, the average hourly pay for protein purification postdoc in the United States is $29.64, according to ZipRecruiter salary data. Most workers in this role earn between $26.68 and $32.69 per hour, depending on experience, location, and employer.

What is a protein purification postdoc?

Protein Purification Postdocs are researchers who have completed their doctoral studies and are engaged in advanced training and research focused on isolating and purifying proteins from various sources. Their work typically involves designing and optimizing purification protocols, analyzing protein structure and function, and supporting broader biochemical or biomedical research projects. They often use techniques such as chromatography, electrophoresis, and affinity tagging. These postdoctoral researchers play a key role in advancing scientific understanding of proteins and developing applications in fields like medicine, biotechnology, and pharmaceuticals.

What are some common challenges faced by protein purification postdocs when scaling up protocols from research to production levels?

Protein Purification Postdocs often encounter challenges when translating small-scale laboratory protocols to larger-scale production, including maintaining protein stability, optimizing yield, and ensuring reproducibility. Differences in buffer composition, equipment limitations, and increased risk of protein degradation can complicate the process. Collaborating closely with upstream (expression) and downstream (analytical) teams is crucial for troubleshooting and achieving consistent results. Gaining experience with a variety of purification systems and techniques can help overcome these challenges and broaden career opportunities in both academia and industry.

What are the key skills and qualifications needed to thrive as a protein purification postdoc, and why are they important?

To thrive as a Protein Purification Postdoc, you need advanced knowledge in biochemistry, molecular biology, and protein chemistry, typically supported by a PhD in a related field. Experience with protein purification systems (such as FPLC and HPLC), analytical techniques (SDS-PAGE, Western blot), and relevant software is essential. Strong problem-solving abilities, meticulous attention to detail, and effective communication skills set outstanding candidates apart. These competencies ensure the efficient isolation and characterization of proteins, which is crucial for high-quality research outcomes.

What are popular job titles related to Protein Purification Postdoc jobs?

For Protein Purification Postdoc jobs, the most frequently searched job titles are:

Infographic showing various Protein Purification Postdoc job openings in the United States as of September 2026, with employment types broken down into 82% Full Time, 14% Part Time, 3% Contract, and 1% Nights. Highlights an 89% Physical, 1% Hybrid, and 10% Remote job distribution, with an average salary of $61,648 per year, or $29.6 per hour.

Postdoctoral Associate in Structural Biology and Biophysics

Piscataway, NJ • On-site

Rutgers University
Education Programs Administration • 1 - 10 employees

Full-time

Medical, Dental, Life, Retirement, PTO

Re-posted 6 days ago


Rutgers University rating

7.7

Company rating: 7.7 out of 10

Based on 68 frontline employees who took The Breakroom Quiz


Job description

Position Details
Position Information
Recruitment/Posting Title
Postdoctoral Associate in Structural Biology and Biophysics
Department
Quantitative Biomedicine Inst
Salary Details
63968
Offer Information
The final salary offer may be determined by several factors, including, but not limited to, the candidate's qualifications, experience, and expertise, and availability of department or grant funds to support the position. We also take into consideration market benchmarks, if and when appropriate, and internal equity to ensure fair compensation relative to the university's broader compensation structure. We are committed to offering competitive and flexible compensation packages to attract and retain top talent.
Benefits
Rutgers provides a comprehensive benefits package to eligible employees. The specific benefits vary based on the position and may include:
  • Medical, prescription drug, and dental coverage
  • Paid vacation, holidays, and various leave programs
  • Competitive retirement benefits, including defined contribution plans and voluntary tax-deferred savings options
  • Employee and dependent educational benefits (when applicable)
  • Life insurance coverage
  • Employee discount programs

Posting Summary
The Deaconescu Lab at Rutgers University has one opening for a postdoctoral researcher. The laboratory's interests lie primarily in microbial stress responses, with particular emphasis on responses to DNA damage, the mechanochemistry of DNA-based motors. We utilize a combination of biochemical, biophysical and structural techniques. (e.g. X-ray crystallography, small-angle X-ray scattering, transmission electron microscopy). For examples of work, please see Brugger et al. JBC (2023, 2024), Brugger et al. Nature Communications (2020), Dorich et al, Genes Development (2019), Vemu et al. Science (2018), Le TT et al. Cell (2018) etc. More information about the lab can be obtained at https://deaconesculab.com
Position Status
Full Time
Posting Number
25FA0742
Posting Open Date
Posting Close Date
Qualifications
Minimum Education and Experience
A successful postdoctoral candidate should hold a PhD in structural biology, biochemistry, biophysics or related field and have an established track-record of publications in peer-reviewed journals, solid experience with protein biochemistry. Prior knowledge of crystallography and/or single-particle electron microscopy is highly desirable. Must be highly motivated and work independently as well as in a team. Excellent spoken and written English are required. New Ph.D. graduates are particularly encouraged to apply.
Certifications/Licenses
Required Knowledge, Skills, and Abilities
Proficiency in molecular biology, protein expression and protein purification, characterization of protein and protein-nucleic acids complexes using various biophysical methods (for example: EMSA, ITC, AUC, FLUORESCENCE ANISOTROPY, BLI, MST, CD etc.). Experience with assay development and molecular microbiology a plus. Research experience in crystallography and cryo-electron microscopy (cryo-EM) is desirable, however not required. The selected candidate will obtain appropriate training in crystallization and crystallographic computing, microscope alignments, data acquisition, image processing and structure calculation using a variety of cryo-EM software. The candidate should be comfortable using Linux. Strong written and oral communication skills in English, as well as the ability to prepare scientific manuscriptsand grant proposals, work independently and collaborate with other scientists are required.
Preferred Qualifications
Equipment Utilized
Standard laboratory equipment including Biorad NGC pure purification systems, Mosquito crystallization robot, centrifuges, PCR cyclers, GelDoc and cell culture incubators. Kulczyk group has several Mac workstations suitable for scientific computing and general manuscript preparation. The Institute for Quantitative Biomedicine houses the state-of-the-art cryo-EM facility: Thermo Fisher Scientific Talos Arctica cryo-EM equipped with a Summit K2 direct electron detector, BioQuantumenergy filter and a Volta phase plate; Aquilos 2 cryo-FIB/SEM; Leica DM6 FS/EM cryo-CLEM system; NMR facility (Bruker 800 MHz and 700 MHz with cryoprobes and two 600 MHz spectrometers); mass spectrometry and super-resolution imaging facilities, and is the world headquarters of the Research Collaboratory for Structural Bioinformatics (RCSB) consortium and the Protein Data Bank (PDB).
Physical Demands and Work Environment
Overview
The Deaconescu Lab at Rutgers University has one opening for a postdoctoral researcher. The laboratory's interests lie primarily in microbial stress responses, with particular emphasis on responses to DNA damage, the mechanochemistry of DNA-based motors. We utilize a combination of biochemical, biophysical and structural techniques. (e.g. X-ray crystallography, small-angle X-ray scattering, transmission electron microscopy). For examples of work, please see Brugger et al. JBC (2023, 2024), Brugger et al. Nature Communications (2020), Dorich et al, Genes Development (2019), Vemu et al. Science (2018), Le TT et al. Cell (2018) etc. More information about the lab can be obtained at https://deaconesculab.com
Statement
Posting Details
Special Instructions to Applicants
Quick Link to Posting
https://jobs.rutgers.edu/postings/257275
Campus
Rutgers University-New Brunswick
Home Location Campus
Busch (RU-New Brunswick)
City
Piscataway
State
NJ
Location Details
Pre-employment Screenings
All offers of employment are contingent upon successful completion of all pre-employment screenings.
Immunization Requirements
Under Policy 100.3.1 Immunization Policy for Covered Individuals, if employment will commence during Flu Season, Rutgers University may require certain prospective employees to provide proof that they are vaccinated against Seasonal Influenza for the current Flu Season, unless the University has granted the individual a medical or religious exemption. Additional infection control and safety policies may apply. Prospective employees should speak with their hiring manager to determine which policies apply to the role or position for which they are applying. Failure to provide proof of vaccination for any required vaccines or obtain a medical or religious exemption from the University will result in rescission of a candidate's offer of employment or disciplinary action up to and including termination.
Equal Employment Opportunity Statement
It is university policy to provide equal employment opportunity to all its employees and applicants for employment regardless of their race, creed, color, national origin, age, ancestry, nationality, marital or domestic partnership or civil union status, sex, pregnancy, gender identity or expression, disability status, liability for military service, protected veteran status, affectional or sexual orientation, atypical cellular or blood trait, genetic information (including the refusal to submit to genetic testing), or any other category protected by law. As an institution, we encourage all qualified applicants to apply. For additional information please see the Non-Discrimination Statement at the following web address: http://uhr.rutgers.edu/non-discrimination-statement

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