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Antibody Engineering Postdoc Jobs (NOW HIRING)

MSD

Scientist

Gaithersburg, MD · On-site

$101K - $154K/yr

D. in Life Sciences, Engineering or related field preferred. o Additional postdoctoral or ... or antibody engineering), and molecular biology OR structural biology and membrane protein ...

Meso Scale Discovery

Scientist

Gaithersburg, MD · On-site

$101K - $154K/yr

D. in Life Sciences, Engineering or related field preferred. o Additional postdoctoral or ... or antibody engineering), and molecular biology OR structural biology and membrane protein ...

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Antibody Engineering Postdoc information

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$34.5K

$111.2K

$183K

How much do antibody engineering postdoc jobs pay per year?

As of Jun 9, 2026, the average yearly pay for antibody engineering postdoc in the United States is $111,182.00, according to ZipRecruiter salary data. Most workers in this role earn between $77,000.00 and $144,000.00 per year, depending on experience, location, and employer.

What are some common challenges faced by Antibody Engineering Postdocs when optimizing antibody affinity and specificity?

Antibody Engineering Postdocs often encounter challenges balancing affinity improvement with maintaining specificity, as enhancing one property can inadvertently compromise the other. Additionally, experimental hurdles such as expression yield, stability, and solubility of engineered antibodies require careful troubleshooting. Collaboration with structural biologists, biochemists, and computational modelers is typically essential to interpret results and iterate designs effectively. Being adaptable and open to interdisciplinary feedback is key to overcoming these complex challenges.

What are Antibody Engineering Postdocs?

Antibody Engineering Postdocs are researchers who have completed their doctoral studies and are engaged in advanced research focused on designing, modifying, and optimizing antibodies for various applications. Their work often involves molecular biology, protein engineering, and immunology to develop antibodies with improved specificity, affinity, or therapeutic potential. These postdoctoral scientists typically work in academic, biotech, or pharmaceutical settings, contributing to projects such as drug discovery, diagnostics, or understanding immune responses. The position is highly collaborative and may include publishing research, mentoring students, and presenting findings at conferences.

What are the key skills and qualifications needed to thrive as an Antibody Engineering Postdoc, and why are they important?

To thrive as an Antibody Engineering Postdoc, you need a PhD in molecular biology, biochemistry, or a related field, with expertise in protein engineering and antibody design. Experience with techniques such as phage display, flow cytometry, and bioinformatics tools, as well as familiarity with relevant laboratory software, is crucial. Strong problem-solving abilities, attention to detail, and effective collaboration and communication skills help you excel in multidisciplinary research environments. These competencies are essential for advancing innovative antibody therapeutics and contributing meaningful scientific discoveries.

What is the difference between Antibody Engineering Postdoc vs Antibody Development Scientist?

AspectAntibody Engineering PostdocAntibody Development Scientist
Required CredentialsPhD in immunology, molecular biology, or related fieldBachelor's or Master's in related sciences, with experience in antibody development
Work EnvironmentAcademic or research institutions, laboratoriesBiotech or pharmaceutical industry, R&D labs
Employer & Industry UsagePrimarily academia, research institutesIndustry-focused, product development companies
Common Search & Comparison IntentUnderstanding research-focused roles in antibody engineeringRoles involved in antibody development and production

While both roles involve working with antibodies, the Antibody Engineering Postdoc is primarily research-oriented, focusing on developing new antibody technologies in academic or research settings. In contrast, the Antibody Development Scientist typically works in industry, focusing on the development, optimization, and production of antibody-based therapeutics or diagnostics.

Infographic showing various Antibody Engineering Postdoc job openings in the United States as of May 2026, with employment types broken down into 100% Full Time. Highlights an 100% In-person job distribution, with an average salary of $111,182 per year, or $53.5 per hour.
Scientist/Senior Scientist, Antibody Engineering

Scientist/Senior Scientist, Antibody Engineering

Arrowhead Pharmaceuticals

San Diego, CA • On-site

$120K - $150K/yr

Full-time

Posted 14 days ago

Job description

Arrowhead Pharmaceuticals, Inc. (Nasdaq ARWR) is a commercial stage biopharmaceutical company that develops medicines that treat intractable diseases by silencing the genes that cause them. Using a broad portfolio of RNA chemistries and efficient modes of delivery, Arrowhead therapies trigger the RNA interference mechanism to induce rapid, deep, and durable knockdown of target genes. RNA interference, or RNAi, is a mechanism present in living cells that inhibits the expression of a specific gene, thereby affecting the production of a specific protein. Arrowhead's RNAi-based therapeutics leverage this natural pathway of gene silencing.
Arrowhead is focused on developing innovative drugs for diseases with a genetic basis, typically characterized by the overproduction of one or more proteins that are involved with disease. The depth and versatility of our RNAi technologies enables us to potentially address conditions in virtually any therapeutic area and pursue disease targets that are not otherwise addressable by small molecules and biologics. Arrowhead is leading the field in bringing the promise of RNAi to address diseases outside of the liver, and our clinical pipeline includes disease targets in the liver and lung with a promising pipeline of preclinical candidates.
Arrowhead's corporate headquarters is in Pasadena, CA with research and development teams in Madison, WI & San Diego, CA, and a state of the art manufacturing facility in Verona, WI. Our employees are nimble, science-driven innovators who are collaborating to bring new therapies to patients in need.
The Position
We are seeking a highly motivated and skilled Molecular Biologist to join our dynamic research team in Discovery Chemistry,. The successful candidate will play a key role in antibody engineering to support platform development and drug delivery initiatives. This position requires extensive hands-on experience in phage display, antibody engineering, and antibody characterization, supported by a strong foundation in molecular biology.
Responsibilities
  • Design and construct mutant phage libraries for antibody affinity maturation or humanization.
  • Perform molecular cloning, mutagenesis, antibody gene assembly, and expression vector design.
  • Express and purify recombinant antibodies using bacterial and mammalian expression systems.
  • Perform binding, specific and in vitro functional assays.
  • Collaborate with cross-functional project teams to advance lead antibodies through drug development stages.
  • Maintain accurate documentation and present findings at internal meetings.

Requirements
  • Ph.D. in Biology, Biochemistry, Molecular Biology, or a related field.
  • Hands-on experience with phage display technology for antibody engineering.
  • Proficiency in molecular cloning, PCR, and mutagenesis.
  • Experience with antibody expression and purification using E. coli, HEK293, and CHO systems.
  • Strong analytical and problem-solving skills, with the ability to troubleshoot experiments independently.
  • Excellent record-keeping, communication, and collaboration skills.
  • Proven ability to adapt to fast pace and evolving research priorities
  • Track record of scientific productivity, including peer-reviewed publications, conference presentations, or patents
  • Additional experience in molecular biology and/or antibody discovery is highly desirable

Preferred
  • Industry or postdoc experience

California pay range
$120,000-$150,000 USD
Arrowhead provides competitive salaries and an excellent benefit package.
Candidates must have current, valid authorization to work in the country where this role is located.
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