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Protein Research Jobs (NOW HIRING)

Jj

Director, Protein Sciences

Spring House, PA

Biotherapeutics R&D Job Category: People Leader All Job Posting Locations: Cambridge, Massachusetts ... The Director, Protein Sciences will integrate target biology insight, computational protein design ...

Jj

Director, Protein Sciences

Cambridge, MA · On-site

Biotherapeutics R&D Job Category: People Leader All Job Posting Locations: Cambridge, Massachusetts ... The Director, Protein Sciences will integrate target biology insight, computational protein design ...

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How much do protein research jobs pay per hour?

As of Aug 19, 2026, the average hourly pay for protein research in the United States is $22.22, according to ZipRecruiter salary data. Most workers in this role earn between $17.31 and $23.80 per hour, depending on experience, location, and employer.

What does a protein research professional do?

Professionals in protein research study the structure, function, and interactions of proteins, which are essential molecules in all living organisms. Their work involves using various laboratory techniques to analyze how proteins work, how they contribute to health and disease, and how they can be engineered or targeted for therapeutic purposes. Protein researchers often collaborate with biologists, chemists, and medical scientists to make discoveries that advance biotechnology, medicine, and drug development.

What are the key skills and qualifications needed to thrive as a protein research scientist?

To thrive as a Protein Research Scientist, you need a solid background in molecular biology, biochemistry, and protein chemistry, typically supported by an advanced degree such as a PhD in a life sciences field. Familiarity with laboratory techniques like mass spectrometry, chromatography, protein purification, and bioinformatics tools is essential, as are certifications in laboratory safety and compliance. Critical thinking, attention to detail, and collaborative communication are important soft skills that help drive innovative research and effective teamwork. These skills and qualifications are crucial for designing experiments, analyzing complex data, and contributing to scientific advancements in protein science.

What are some common challenges faced by professionals working in protein research, and how are they typically addressed?

Professionals in protein research often encounter challenges such as protein instability, difficulties in protein expression and purification, and the complexity of analyzing protein structures and functions. These issues are typically addressed by optimizing expression systems, employing advanced purification techniques, and collaborating with colleagues in bioinformatics, structural biology, and analytical chemistry. Close teamwork and ongoing learning are essential, as researchers may need to adapt protocols or use new technologies to overcome technical obstacles and advance their projects.

What is the difference between Protein Research vs Biochemist?

AspectProtein ResearchBiochemist
Required CredentialsBachelor's or Master's in Biochemistry, Molecular Biology, or related fieldsBachelor's, Master's, or Ph.D. in Biochemistry or related disciplines
Work EnvironmentLaboratories, research institutions, biotech companiesLaboratories, pharmaceutical companies, academic settings
Industry UsageFocused on studying proteins, their functions, and interactionsBroader focus on chemical processes in living organisms, including proteins
Common Search/ComparisonOften compared for research roles in molecular biologyMore general, but overlaps in research areas

Protein Research specifically concentrates on studying proteins, their structures, functions, and interactions, often within specialized research settings. Biochemists have a broader scope, exploring various chemical processes in living organisms, including but not limited to proteins. Both roles require similar educational backgrounds and work environments, but Protein Research is more specialized in protein-focused studies.

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protein research jobs near you
Infographic showing various Protein Research job openings in the United States as of August 2026, with employment types broken down into 1% Internship, 1% As Needed, 85% Full Time, 11% Part Time, and 2% Contract. Highlights an 84% Physical, 4% Hybrid, and 12% Remote job distribution, with an average salary of $46,222 per year, or $22.2 per hour.

Research Scientist I - Protein Sciences and Structural Biology

Broad Institute

Cambridge, MA • On-site

$88K - $124K/yr

Full-time

Medical, Dental, Vision, Life, Retirement, PTO

Re-posted 4 days ago

Job description

General information
Location
Cambridge, MA
Ref #
44535
Job Family
Research
Date published
08/12/2026
Time Type
Full time
Pay Range
$88,000.00/yr - $124,000.00/yr
Description & Requirements
Embedded within the Broad Institute, the Center for the Development of Therapeutics (CDoT) is a highly collaborative organization of professional drug discovery scientists. Our mission is to translate cutting edge biological insights originating from the Broad community into impactful drug discovery projects. We partner with faculty from MIT, Harvard, and the Harvard teaching hospitals together with industry partners in pharmaceutical, biotechnology and venture capital firms to validate druggable targets and identify leads. We combine our deep expertise in drug discovery with the knowledge and unique capabilities of the Broad Institute to explore drug discovery projects in a wide range of disease areas (including oncology, cardiovascular, psychiatry, infectious and rare diseases). We use systematic approaches in genomics, biology, high content imaging, chemistry, and machine learning coupled with the Broad's culture of creativity, risk taking, and open sharing, to successfully advance science and develop new treatments for patients.
We are seeking a passionate and highly motivated Research Scientist I to join CDoT's Protein Technologies team. The successful candidate will have a solid understanding of protein construct design, expression, purification, and quality assessment. Experience in structural biology is advantageous.
Principle Duties and Responsibilities:
  • Developing and executing strategies to clone and express recombinant proteins in a variety of expression systems
  • Purifying tagged or native proteins using standard purification (FPLC systems and column chromatography) and analytical techniques (SDS-PAGE, Western blot, light scattering, and protein LC/MS)
  • With training, produce high quality protein crystal structures and co-crystal structures, carrying out the process from crystallization screening through to structure refinement
  • Initiating and completing routine protein construct design and production in an independent and efficient manner
  • Demonstrating the ability to interpret experimental outcomes and proposing follow-up studies
  • Troubleshooting and solving scientific problems related to protein production independently
  • Operating and maintaining lab equipment independently, including protein purification systems like an AKTA pure
  • Investigating new technologies related to protein expression and purification
  • Documenting work and effectively presenting results in cross-functional project teams

Requirements:
  • Ph.D in Biophysics, Biochemistry, Molecular Biology, Structural Biology or related life science field with 0-2+ years of research experience in an industrial or academic setting
  • Expertise in recombinant protein purification using chromatography (affinity, ion exchange, and size exclusion)
  • Significant experience with cloning and expressing proteins using different vectors, tags, and various cell culture systems (mammalian, insect, bacterial, yeast)
  • Significant experience with protein characterization (analytical size exclusion chromatography, mass spectrometry, light scattering, western blot and biophysical binding studies)
  • Experience in protein crystallography and crystallographic data processing, model refinement, and structural analysis is a plus
  • Experience with biophysical characterization of proteins (ITC, DSC, SPR, NMR etc.) is a plus
  • A proven record of successful interaction with project team members, external customers or vendors

The successful candidate will be a results-focused, team-oriented, creative bench scientist able to excel in a fast-track environment. She or he must be self-motivated, detail-oriented and exhibit strong problem solving skills. In addition, the successful candidate should be a clear and effective communicator, demonstrating strong interpersonal skills to enable collaboration with project teams, peers, and management in identifying and achieving research goals.
The expected base pay range for this position as listed above is based on a 40 hour per week schedule. Broad provides pay ranges representing its reasonable and good faith estimate of what the organization reasonably expects to pay for a position at the time of posting. Actual compensation will vary based on factors including but not limited to, relevant skills, experience, education, qualifications, and other factors permissible by law.
At Broad, your base pay is just one part of a comprehensive total rewards package. From day one, this role offers a competitive benefits package including medical, dental, vision, life, and disability insurance; a 401(k) retirement plan; flexible spending and health savings accounts; at least 13 paid holidays; winter closure; paid time off; parental and family care leave; and an employee assistance program, among other Broad benefits.
The Broad Institute is an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, national origin, religion, age, color, sex, disability, protected veteran status, or any other characteristic protected by local, state, or federal laws, rules, or regulations.
Should you need a reasonable accommodation to complete the application or interview process, please contact recruiting@broadinstitute.org for assistance.

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