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Wet Lab Jobs in Minnesota (NOW HIRING)

Celcuity

Bioinformatics Scientist

Minneapolis, MN · On-site

$110K - $120K/yr

Successfully execute bioinformatics studies in collaboration with other R&D wet-lab scientists, clinical teams and bioinformaticians on multiple defined priority areas. * Effectively communicate ...

Celcuity

Bioinformatics Scientist

Minneapolis, MN · On-site

Successfully execute bioinformatics studies in collaboration with other R&D wet-lab scientists, clinical teams and bioinformaticians on multiple defined priority areas. * Effectively communicate ...

Actalent

Lab Technician

Saint Paul, MN · On-site

$18.50 - $24.75/hr

Lab Technician This Lab Technician role focuses on conducting chemical and physical laboratory ... Collaborate with cross-functional teams to support quality assurance, analytical chemistry, and wet ...

Actalent

Chemistry Lab Technician

Saint Paul, MN · On-site

$19.25 - $25.50/hr

Foundational knowledge of chemistry, including wet chemistry concepts. * Experience working in a ... The lab runs an average of about 200 samples per shift, with roughly 50 samples handled per person ...

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$12

$22

$33

How much do wet lab jobs pay per hour?

As of Aug 4, 2026, the average hourly pay for wet lab in Minnesota is $22.07, according to ZipRecruiter salary data. Most workers in this role earn between $17.88 and $23.80 per hour, depending on experience, location, and employer.

What is a wet lab?

A Wet Lab job involves conducting experiments that require handling liquids, chemicals, biological samples, or other wet materials in a controlled lab environment. Wet lab scientists and technicians perform tasks such as sample preparation, chemical mixing, and data analysis to support research in fields like biology, chemistry, and medicine. These roles typically require knowledge of lab safety protocols, proper equipment usage, and scientific techniques.

What are the typical daily responsibilities in a wet lab position?

In a Wet Lab position, your daily tasks may include preparing and running experiments, analyzing samples using specialized equipment, maintaining and calibrating instruments, and accurately recording data in lab notebooks or digital systems. You will also be responsible for keeping the lab clean and organized, adhering to safety protocols, and properly storing chemicals and biological materials. Collaboration is common, as you may work with other lab technicians, scientists, or research teams to support ongoing projects. This hands-on role is ideal for those who enjoy problem-solving and actively contributing to exciting scientific advancements.

What are the key skills and qualifications needed to thrive in a wet lab position?

To thrive in a Wet Lab role, you need a solid understanding of laboratory techniques, safety protocols, and scientific methodology, often supported by a degree in biology, chemistry, or a related field. Familiarity with instruments like pipettes, centrifuges, spectrophotometers, and lab management software is typically required, along with knowledge of compliance standards such as GLP or OSHA. Strong attention to detail, problem-solving ability, and effective communication are valuable soft skills for managing experiments and collaborating with teammates. These qualities are essential to ensure accurate results, maintain a safe and organized lab environment, and contribute effectively to research objectives.

What are the wet lab tasks?

Wet lab tasks involve hands-on experimental work in a laboratory setting, including preparing solutions, handling biological samples, performing assays, and operating laboratory equipment such as pipettes, centrifuges, and microscopes. These tasks require attention to detail, proper safety procedures, and often involve data recording and analysis. Wet lab technicians may also assist with maintaining lab cleanliness and ensuring compliance with safety standards.
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What cities in Minnesota are hiring for Wet Lab jobs? Cities in Minnesota with the most Wet Lab job openings:
Wet Lab jobs near you
Infographic showing various Wet Lab job openings in Minnesota as of July 2026, with employment types broken down into 3% As Needed, 74% Full Time, 13% Part Time, and 10% Contract. Highlights an 97% Physical, 1% Hybrid, and 2% Remote job distribution, with an average salary of $45,899 per year, or $22.1 per hour.

Research Fellow - Neurology - Cousin lab

Mayo Clinic

Rochester, MN • On-site

Full-time

Medical, Dental, Vision, Retirement

Posted 16 days ago

Mayo Clinic rating

7.8

Company rating: 7.8 out of 10

Based on 693 frontline employees who took The Breakroom Quiz

132nd of 887 rated healthcare providers

Job description


The Cousin Lab at Mayo Clinic is seeking a postdoctoral fellow will contribute to a growing rare disease therapeutics program with an initial emphasis on POLR2A-related disorders. This work will also support broader efforts in the lab, including genetic forms of ALS and other monogenic neurologic conditions. Projects may include iPSC-derived neural models, variant-mechanism studies, RNA-targeted therapies, genome editing, sequencing-based biomarkers, and collaboration with Mayo Clinic precision medicine and N-of-1 therapeutic programs, core facilities, and external academic partners.
The Cousin Lab at Mayo Clinic develops mechanism-guided, gene-targeted therapeutic strategies for rare neurogenetic diseases. Our work integrates clinical genetics, patient-derived biospecimens, functional genomics, iPSC-based disease modeling, preclinical therapeutic testing, and clinical translation.
Position Overview
The fellow will lead experimental and analytical components of translational rare disease projects. The role includes developing and characterizing patient-derived and engineered cell models; defining variant effects and disease mechanisms; designing and evaluating RNA-targeted and gene-editing therapeutic strategies; and integrating functional, genomic, and clinical data to prioritize treatment approaches. The position involves substantial wet-lab research, quantitative data analysis, manuscript and grant preparation, and cross-disciplinary collaboration.
The fellow will join a collaborative Mayo Clinic environment with access to clinical expertise, core facilities, genomic and sequencing resources, translational infrastructure, and multi-institutional rare disease networks. This position offers the opportunity to develop an independent research niche at the interface of rare disease biology, human neural modeling, and targeted therapeutic development; publish first-author manuscripts; present at national and international meetings; and pursue external fellowship or career-development funding.
Key Responsibilities
  • Disease Modeling & Assay Development: Develop and characterize patient-derived and engineered disease models, including fibroblasts, iPSCs, isogenic controls, iPSC-derived neural cell types, and organoid or multicellular systems.
  • Mechanistic & Functional Studies: Design and execute molecular, cellular, imaging, electrophysiologic, and functional genomics assays to define variant effects, disease mechanisms, cellular phenotypes, biomarkers, and therapeutic response.
  • Therapeutic Development: Develop and evaluate RNA-targeted and gene-editing strategies, including ASO/siRNA, allele-selective or splice-modifying approaches, CRISPR/base-editing platforms, delivery systems, and target-engagement or rescue assays.
  • Genomic Data Integration: Integrate variant interpretation, sequencing data, and functional readouts to prioritize therapeutic strategies and evaluate loss-of-function, dominant-negative, allele-specific, and related mechanisms.
  • Collaboration & Translation: Coordinate with the PI, clinicians, partners, core facilities, biobanks, and external collaborators to align patient samples, disease models, assays, and preclinical workflows.
  • Scientific Communication & Mentorship: Manage projects with rigor and reproducibility; prepare figures, reports, manuscripts, presentations, and grant/fellowship applications; and contribute to mentoring junior team members.

Qualifications
  • Education: Ph.D., M.D./Ph.D., or equivalent doctoral degree in neuroscience, genetics/genomics, molecular or cell biology, stem cell biology, biomedical engineering, pharmacology, RNA biology, bioengineering, or a related field.
  • Research Expertise: Demonstrated productivity in cell-based disease modeling, molecular biology, functional genomics, therapeutic development, neurogenetics, or rare disease biology.
  • Technical Skills: Strong wet-lab skills in aseptic cell culture, molecular biology, assay development, sequencing workflows, microscopy/imaging, and experimental documentation.
  • Quantitative & Analytical Skills: Ability to analyze, interpret, and communicate complex data; familiarity with Prism, R, Python, or related statistical and visualization tools is helpful.
  • Professional Skills: Excellent organization, independence, attention to detail, and communication skills, with the ability to thrive in a collaborative translational research environment.

Experience in one or more of the following areas is preferred:
  • iPSC & Neural Models: Experience with human iPSC culture, genome-edited/isogenic lines, neural differentiation, neurons, glia, organoids, or related iPSC-derived neural models.
  • Therapeutic Platforms: Experience with RNA-targeted therapeutic development, genome engineering, or delivery platforms, including ASOs, siRNA, CRISPR/Cas, base or prime editing, AAV, or LNPs.
  • Rare Disease Translation: Experience with rare genetic, neurodevelopmental, or neuromuscular disease models; patient-derived biospecimens; variant interpretation; genotype-phenotype analysis; or individualized/N-of-1 therapeutic approaches.
  • Genomics & Biomarkers: Experience with RNA-seq, long-read sequencing, phasing/haplotype analysis, single-cell or multi-omic workflows, biomarker discovery, bioinformatics, or high-content/high-throughput screening.
  • Scientific Leadership: Experience in translational or preclinical research, collaborative project management, manuscript preparation, grant writing, and mentoring.

Candidates should submit a CV, a brief cover letter describing research interests and relevant experience and contact information for 2-3 references.
About Us
Why Mayo Clinic
Mayo Clinic is top-ranked in more specialties than any other care provider according to U.S. News & World Report. As we work together to put the needs of the patient first, we are also dedicated to our employees, investing in competitive compensation and comprehensive benefit plans - to take care of you and your family, now and in the future. And with continuing education and advancement opportunities at every turn, you can build a long, successful career with Mayo Clinic.
Benefits Highlights
  • Medical: Multiple plan options.
  • Dental: Delta Dental or reimbursement account for flexible coverage.
  • Vision: Affordable plan with national network.
  • Pre-Tax Savings: HSA and FSAs for eligible expenses.
  • Retirement: Competitive retirement package to secure your future.

About the Team
Just as our reputation has spread beyond our Minnesota roots, so have our locations. Today, our employees are located at our three major campuses in Phoenix/Scottsdale, Arizona, Jacksonville, Florida, Rochester, Minnesota, and at Mayo Clinic Health System campuses throughout Midwestern communities, and at our international locations. Each Mayo Clinic location is a special place where our employees thrive in both their work and personal lives. Learn more about what each unique Mayo Clinic campus has to offer, and where your best fit is.
Equal Opportunity
All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, gender identity, sexual orientation, national origin, protected veteran status or disability status. Learn more about the "EOE is the Law". Mayo Clinic participates in E-Verify and may provide the Social Security Administration and, if necessary, the Department of Homeland Security with information from each new employee's Form I-9 to confirm work authorization.

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About Mayo Clinic

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Mayo Clinic is the largest integrated, not-for-profit medical group practice in the world. We're building the future, one where the best possible care is available to everyone — and more people can heal at home. Our relentless research turns into earlier diagnoses and new cures. That's how we inspire hope in those who need it most. At Mayo Clinic, experts work together to solve the most challenging unmet needs of patients. Our history of innovation dates back almost 150 years, when brothers Will and Charlie Mayo pioneered an integrated, team-based approach to medicine. Today, that trailblazing spirit drives innovations like Mayo Clinic Platform — which powers new technologies to change how care is delivered to all.

Industry

Hospitals

Company size

10,000+ Employees

Headquarters location

Rochester, MN, US

Year founded

1919

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