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Weekend Only Rn Jobs in Missouri (NOW HIRING)

We are hiring a registered nurse (RN) to join our Pulmonary PCU unit at Saint Luke's at the Plaza ... Our employees are proud to work for the only faith-based, nonprofit, locally owned health system in ...

We are hiring a registered nurse (RN) to join our Pulmonary PCU unit at Saint Luke's at the Plaza ... Our employees are proud to work for the only faith-based, nonprofit, locally owned health system in ...

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Weekend Only Rn information

See Missouri salary details

$9

$30

$64

How much do weekend only rn jobs pay per hour?

As of Aug 19, 2026, the average hourly pay for weekend only rn in Missouri is $30.80, according to ZipRecruiter salary data. Most workers in this role earn between $18.84 and $39.36 per hour, depending on experience, location, and employer.

What is a Weekend Only RN?

A Weekend Only RN is a registered nurse who works exclusively on weekends, typically covering shifts on Saturdays and Sundays. These positions are designed to ensure continuous patient care during weekends when staffing needs may be higher or regular staff are off-duty. Weekend Only RNs may work longer shifts or have different compensation structures, such as premium pay, to account for their unique schedules. This role is common in hospitals, long-term care facilities, and other healthcare settings that require 24/7 nursing coverage.

What are the key skills and qualifications needed to thrive as a Weekend Only RN, and why are they important?

To thrive as a Weekend Only RN, you need an active RN license, strong clinical assessment skills, and an ability to provide comprehensive patient care, often with significant autonomy. Familiarity with electronic health records (EHRs), medication administration systems, and hospital protocols is necessary. Excellent time management, adaptability, and communication skills are crucial to handle higher patient loads and collaborate with weekend staff. These skills ensure safe, efficient, and high-quality care during weekend shifts when resources and support may be more limited.

What are some common challenges faced by Weekend Only RNs and how can they be managed?

Weekend Only Registered Nurses often encounter challenges such as higher patient volumes, limited access to certain support staff, and the need for efficient communication with weekday teams. Managing these challenges requires strong organizational skills, adaptability, and the ability to prioritize tasks effectively. Building rapport with colleagues and staying updated through thorough handoffs can help ensure seamless patient care and a smoother workflow during weekends.

What is the difference between Weekend Only Rn vs Weekend Only Lpn?

AspectWeekend Only RnWeekend Only Lpn
CertificationsRegistered Nurse (RN) licenseLicensed Practical Nurse (LPN) license
Work EnvironmentHospitals, clinics, long-term care facilitiesAssisted living, nursing homes, outpatient clinics
Job ResponsibilitiesAdvanced patient assessments, medication administration, care planningBasic patient care, vital signs, assisting with daily activities

Weekend Only Rns typically hold a registered nurse license and perform more complex medical tasks, working in hospitals or clinics. Weekend Only Lpns have a practical nursing license, focusing on basic patient care in assisted living or nursing homes. Both roles are popular for weekend work, but Rns generally handle more advanced responsibilities.

What cities in Missouri are hiring for Weekend Only Rn jobs?

Cities in Missouri with the most Weekend Only Rn job openings:

Infographic showing various Weekend Only Rn job openings in Missouri as of August 2026, with employment types broken down into 1% As Needed, 68% Full Time, 25% Part Time, 5% Contract, and 1% Nights. Highlights an 93% Physical, 1% Hybrid, and 6% Remote job distribution, with an average salary of $64,061 per year, or $30.8 per hour.

Clinical Pharmacist- Hospital - Weekend Only Option - $10K Sign-on bonus

Mercy

Springfield, MO

$107K - $128K/yr

Full-time

Medical, Dental, Vision, Retirement, PTO

Re-posted 8 days ago


Mercy rating

6.5

Company rating: 6.5 out of 10

Based on 209 frontline employees who took The Breakroom Quiz

604th of 888 rated healthcare providers


Job description

Find your calling at Mercy! Works with members of the health care team to provide safe and effective drug therapy. Serves as a drug information resource to pharmacy, nursing, and medical staffs as well as to patients. Performs duties and responsibilities in a manner consistent with our mission, values, and Mercy Service Standards. Position Details:
Clinical Pharmacist – Hospital (Weekend Only)

$10,000 Sign-On Bonus (Paid at 6, 12, 18, and 24 months)

Position Summary

The Clinical Pharmacist collaborates with members of the healthcare team to deliver safe, effective, and evidence-based medication therapy. This role serves as a key drug information resource for pharmacy, nursing, and medical staff, as well as patients. The Clinical Pharmacist practices in alignment with organizational mission, values, and service standards, while ensuring high-quality patient care and regulatory compliance.

Schedule
  • Weekend Only Option
  • Three 12-hour shifts: Friday–Sunday
Key ResponsibilitiesClinical Practice
  • Evaluate medication orders and patient records to ensure appropriateness of therapy.
  • Assess patient conditions and develop individualized medication care plans that minimize adverse effects.
  • Monitor drug therapies through chart review and interdisciplinary collaboration; intervene when necessary.
  • Consult with physicians, nurses, and patients regarding medication selection, dosing, administration, interactions, and side effects.
  • Document medication plans, interventions, and patient outcomes accurately.
  • Provide recommendations on drug therapy, including dose, route, schedule, contraindications, and potential interactions.
  • Serve as a clinical resource with developing or maintaining subspecialty expertise.
Collaboration & Patient Care
  • Partner with healthcare teams to ensure optimal patient outcomes.
  • Maintain positive working relationships with medical and nursing staff.
  • Provide education and guidance to patients and caregivers on medication use.
Quality, Safety & Compliance
  • Adhere to all confidentiality, safety, and risk management policies.
  • Participate in quality improvement initiatives, including medication use evaluations and adverse drug reaction reporting.
  • Ensure compliance with regulatory, licensing, and accreditation standards.
  • Complete required inspections (e.g., expiration dating, floor stock checks) and safety training.
Education & Professional Development
  • Participate in precepting pharmacy students and residents.
  • Support continuing education through presentations, in-services, and staff training.
  • Contribute to competency development for pharmacy team members.
  • Attend conferences, workshops, and maintain licensure requirements.
Operations & Coordination
  • Coordinate activities with department staff to ensure efficient workflow.
  • Exercise sound judgment in prioritizing tasks and managing resources.
  • Participate in departmental initiatives, committees, and policy reviews.
Technology & Systems
  • Utilize pharmacy information systems for order verification and clinical documentation (e.g., Epic).
  • Access and apply drug information resources (e.g., Micromedex).
  • Operate pharmacy automation systems (e.g., Omnicell, McKesson, ScriptPro) as needed.
Professionalism
  • Demonstrate exceptional communication and customer service aligned with service standards.
  • Maintain professionalism, teamwork, and respect in all interactions.
  • Adhere to dress code, hygiene standards, and PPE requirements.
  • Effectively manage workload and meet deadlines in a fast-paced environment.
Minimum QualificationsEducation
  • Bachelor of Science in Pharmacy (BS) or Doctor of Pharmacy (PharmD) from an accredited school of pharmacy
Licensure
  • Current pharmacist license in the state of practice
Why Join Us?
  • Competitive Weekend-Only Schedule
  • $10,000 Sign-On Bonus with structured payout
  • Collaborative, patient-centered work environment
  • Opportunities for professional growth, teaching, and clinical specialization
Why Mercy?

From day one, Mercy offers outstanding benefits - including medical, dental, and vision coverage, paid time off, tuition support, and matched retirement plans for team members working 32+ hours per pay period.

Join a caring, collaborative team where your voice matters. At Mercy, you'll help shape the future of healthcare through innovation, technology, and compassion. As we grow, you'll grow with us.


keyword(s): Pharm, Pharmacist, Clinical Pharmacist, Critical Care Pharmacist

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About Mercy

Sourced by ZipRecruiter

Our mission is clear. We bring to life a healing ministry through our compassionate care and exceptional service. At Mercy, we believe in careers that match the unique gifts of unique individuals - careers that not only make the most of your skills and talents, but also your heart.

Industry

Health care and social assistance

Company size

10,000+ Employees

Headquarters location

Chesterfield, MO, US

Year founded

1827