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Weekend Laboratory Jobs in Rochester, MN (NOW HIRING)

Must be available to work weekends, overnight, and holiday shifts. Visa sponsorship is not available for this role. Qualifications Bachelor's degree in Medical Technology (MT), Medical Laboratory ...

... Weekend Schedule Varies International Assignment No Recruiter Jenny StephensQualifications: A Bachelor's degree in Biology, Chemistry, Histotechnology, Medical Laboratory Science, or related and HTL ...

Must be available to work weekends, overnight, and holiday shifts. Visa sponsorship is not available for this role. Qualifications Bachelor's degree in Medical Technology (MT), Medical Laboratory ...

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Weekend Laboratory information

See Rochester, MN salary details

$9

$25

$45

How much do weekend laboratory jobs pay per hour?

As of Jun 30, 2026, the average hourly pay for weekend laboratory in Rochester, MN is $25.66, according to ZipRecruiter salary data. Most workers in this role earn between $19.57 and $28.37 per hour, depending on experience, location, and employer.

What should I expect in terms of workload and collaboration when working as a Weekend Laboratory Technician?

As a Weekend Laboratory Technician, you can expect a steady workload focused on running routine tests, processing samples, and maintaining lab equipment. While weekend shifts may have fewer staff on-site, you will likely collaborate closely with other technicians, nurses, or on-call supervisors to ensure timely and accurate results. Communication is key, as you may need to update weekday teams on outstanding tasks or findings. This role is ideal for those who are comfortable working independently while still engaging with a supportive team environment.

What are the key skills and qualifications needed to thrive as a Weekend Laboratory Technician, and why are they important?

To thrive as a Weekend Laboratory Technician, you need a solid background in laboratory sciences, attention to detail, and typically an associate’s or bachelor’s degree in a related field. Familiarity with laboratory instruments, data entry systems, and adherence to safety protocols are crucial, and certifications like ASCP can be advantageous. Strong organizational skills, problem-solving abilities, and effective communication help you manage workload and collaborate during limited weekend staffing. These skills ensure accurate test results, maintain lab safety, and support efficient operations during off-peak hours.

What are weekend laboratory jobs?

Weekend laboratory jobs are positions within laboratory settings that require employees to work primarily during weekends. These roles can include lab technicians, researchers, or assistants who perform tasks such as preparing samples, conducting experiments, analyzing results, and maintaining lab equipment. Weekend shifts are often essential for laboratories that operate around the clock or need staff coverage outside of regular weekday hours. These jobs suit individuals seeking flexible schedules or additional income. They may also provide valuable hands-on experience for students or professionals entering scientific fields.
What are the most commonly searched types of Laboratory jobs in Rochester, MN? The most popular types of Laboratory jobs in Rochester, MN are:
What are popular job titles related to Weekend Laboratory jobs in Rochester, MN? For Weekend Laboratory jobs in Rochester, MN, the most frequently searched job titles are:
What job categories do people searching Weekend Laboratory jobs in Rochester, MN look for? The top searched job categories for Weekend Laboratory jobs in Rochester, MN are:
What cities near Rochester, MN are hiring for Weekend Laboratory jobs? Cities near Rochester, MN with the most Weekend Laboratory job openings:
Infographic showing various Weekend Laboratory job openings in Rochester, MN as of June 2026, with employment types broken down into 62% Full Time, 34% Part Time, and 4% Contract. Highlights an 93% Physical, 1% Hybrid, and 6% Remote job distribution, with an average salary of $53,383 per year, or $25.7 per hour.
Clinical Laboratory Technologist/Scientist - CLT/CLS/MLS

Clinical Laboratory Technologist/Scientist - CLT/CLS/MLS

Mayo Clinic

Rochester, MN • On-site

Full-time

Posted 11 days ago


Key responsibilities

  • Performs analyses on blood, tissue, and body fluids to aid health care providers in the diagnosis, prognosis, and treatment of patients.

  • Operates and maintains laboratory instruments, troubleshoots assays, evaluates tests for accuracy, and assists with interpreting results.

  • Works with multiple computer systems to retrieve information and report results.


Mayo Clinic rating

7.9

Company rating: 7.9 out of 10

Based on 686 frontline employees who took The Breakroom Quiz

104th of 877 rated healthcare providers


Job description

Are you looking to further develop your career within Clinical Labs? We invite you to explore our Clinical Lab Technologist - Clinical Lab Science opportunities, where you will perform tests on specimens from Mayo Clinic, its affiliated laboratory services, and from clinics and hospitals around the world! 

Mayo Clinic is top-ranked in more specialties than any other hospital according to U.S. News & World Report 2023-2024. We are excited to invite you to be a part of our team within the Department of Laboratory Medicine & Pathology (DLMP) where you'll discover a culture of teamwork, professionalism, mutual respect, and most importantly, a life-changing career! 

Visit the Clinical Labs career site to watch a brief video of Dalena describing a role as a Clinical Laboratory Technologist at Mayo Clinic. 

It is Mayo Clinic's mission to provide excellent, culturally relevant care to all patients in a welcoming environment that champions a culture of belonging for all. In DLMP, we aim to build a workforce that reflects the communities we serve by creating a safe work environment where differences are valued, allowing individuals to achieve and contribute to their fullest potential. By leveraging the strengths that everyone brings to the table, we gain the strategic advantages of accelerated innovation, better problem solving, enhanced productivity and job satisfaction, improved quality, and, most importantly, we find better ways to meet the needs of our patients.

Position Responsibilities:

  • Performs analyses on blood, tissue, and body fluids to aid health care providers in the diagnosis, prognosis, and treatment of patients.
  • Testing is performed in specialized laboratories and may include highly skilled manual techniques or automated testing using sophisticated instrumentation.
  • Responsibilities may include but are not limited to instrument operation and maintenance, troubleshooting assays, evaluating tests for accuracy, assisting with interpreting results, and operational support activities to optimize testing.
  • Works with multiple computer systems to retrieve information and report results.
  • May work with minimal supervision and may assist with specimen collection.
  • Must strictly adhere to safety protocols to work with infectious specimens, chemicals and other hazards.
  • Must be capable of producing accurate results under time constraints, multi-tasking, and performing in a fast-paced and changing environment.
  • Experience with operation and troubleshooting of laboratory instrumentation and assay systems is desirable.
  • Must possess good communication skills and be able to work closely with others.
  • Must be able to accommodate scheduling adjustments, off-shifts, holiday, on-call, and weekend work assignments.
  • Actively partners with team members by fostering an inclusive work environment and respecting others with different backgrounds, experiences, and perspectives. 

*Individuals hired to this position are asked to complete 2 years in the role before being eligible to transfer to other positions within Mayo Clinic*

**This position is not eligible for visa sponsorship. Also, Mayo Clinic DOES NOT participate in the F-1 STEM OPT extension program**

Why Mayo Clinic

Mayo Clinic is top-ranked in more specialties than any other care provider according to U.S. News & World Report. As we work together to put the needs of the patient first, we are also dedicated to our employees, investing in competitive compensation and comprehensive benefit plans - to take care of you and your family, now and in the future. And with continuing education and advancement opportunities at every turn, you can build a long, successful career with Mayo Clinic.
Just as our reputation has spread beyond our Minnesota roots, so have our locations. Today, our employees are located at our three major campuses in Phoenix/Scottsdale, Arizona, Jacksonville, Florida, Rochester, Minnesota, and at Mayo Clinic Health System campuses throughout Midwestern communities, and at our international locations. Each Mayo Clinic location is a special place where our employees thrive in both their work and personal lives. Learn more about what each unique Mayo Clinic campus has to offer, and where your best fit is. 

Equal Opportunity

All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, gender identity, sexual orientation, national origin, protected veteran status or disability status. Learn more about the "EOE is the Law".  Mayo Clinic participates in E-Verify and may provide the Social Security Administration and, if necessary, the Department of Homeland Security with information from each new employee's Form I-9 to confirm work authorization.

Graduate or student graduating within three months with a bachelor's degree in:

Clinical Laboratory Technologist-CLT

Bachelor's degree in chemistry or a biological science (such as, but may not be limited to Biology, Biochemistry, Microbiology, Genetics, etc.) is required.

Clinical Laboratory Technologist-CLS

Graduate with a Bachelor's degree in:

  • Medical Laboratory Science (MLS)
  • Clinical Laboratory Science (CLS)
  • Medical Technology (MT)

Or Bachelor's degree plus Certificate in Medical Laboratory Science (MLS), Clinical Laboratory Science (CLS), Medical Technology (MT), as recognized by the National Accrediting Agency for Clinical Laboratory Sciences (NAACLS) is required. A HEW certificate may be substituted for the specified degree. 

Candidate must satisfy one more of the following qualifications to be considered:

  • Hold an MLS/CLS degree
  • Are a current contracted (contingent) employee within the Department of Laboratory Medicine & Pathology (DLMP) seeking permanent placement in another DLMP Laboratory
  • Are a current Mayo Clinic employee, not currently in a CLT/CLS role
  • Former employee of Mayo Clinic
  • Former Summer Laboratory Science Program participant
  • Are graduates of the Mayo Clinic School of Health Sciences Medical Laboratory Science Program

Additional Qualifications

  • Resume 
  • Cover Letter 
  • Transcripts (unofficial copy accepted) or NACES detailed international equivalency for foreign degrees.  
  • Internal candidates must provide their past three performance appraisals. 

To be considered, ALL MUST be included in the cover letter drop box of the Supporting Documents/URLs section in your application:

  • Resume 
  • Cover Letter 
  • Transcripts (unofficial copy accepted) or NACES detailed international equivalency for foreign degrees.  
  • Internal candidates must provide their past three performance appraisals. 

* For international/foreign trained applicants, it is the responsibility of the international/foreign to provide to Mayo Clinic the following information. The applicant is responsible for the cost associated with obtaining the equivalency evaluation. 

International Transcript:

  • MUST have a DETAILED equivalency evaluation.
  • MUST show US equivalent degree.
  • Evaluation MUST be completed from an organization listed as a member of the National Association of Credential Evaluation Services (NACES) www.naces.org OR the Association of International Credential Evaluators, Inc. (AICE) www.aice-eval.org.

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About Mayo Clinic

Sourced by ZipRecruiter

Mayo Clinic is the largest integrated, not-for-profit medical group practice in the world. We're building the future, one where the best possible care is available to everyone — and more people can heal at home. Our relentless research turns into earlier diagnoses and new cures. That's how we inspire hope in those who need it most. At Mayo Clinic, experts work together to solve the most challenging unmet needs of patients. Our history of innovation dates back almost 150 years, when brothers Will and Charlie Mayo pioneered an integrated, team-based approach to medicine. Today, that trailblazing spirit drives innovations like Mayo Clinic Platform — which powers new technologies to change how care is delivered to all.

Industry

Hospitals

Company size

10,000+ Employees

Headquarters location

Rochester, MN, US

Year founded

1919