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Weekend Clinical Trial Rn Jobs (NOW HIRING)

Clinical Trial Manager

$130K - $150K/yr

Bachelor's degree in life sciences, nursing, or a related field * 2+ years of experience in on-site clinical monitoring and 2+ years of Clinical Trial Manager experience within the pharmaceutical or ...

Clinical Research experience required * RN license preferred * CCRC preferred * Minimum 2 years of Clinical Trial Educator experience and/or healthcare education preferred * Community engagement ...

We are looking for a Clinical Trial Leader (CTL) to join our A-team (office-based*/remote). As a ... A degree in life sciences or nursing qualification preferred, but notrequired. * A minimum ...

We are looking for a Clinical Trial Leader (CTL) to join our A-team (office-based*/remote). As a ... A degree in life sciences or nursing qualification preferred, but not required. * A minimum ...

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How much do weekend clinical trial rn jobs pay per hour?

As of May 31, 2026, the average hourly pay for weekend clinical trial rn in the United States is $62.52, according to ZipRecruiter salary data. Most workers in this role earn between $50.72 and $70.43 per hour, depending on experience, location, and employer.

What are the key skills and qualifications needed to thrive as a Weekend Clinical Trial RN, and why are they important?

To thrive as a Weekend Clinical Trial RN, you need a current RN license, clinical nursing experience, and a solid understanding of Good Clinical Practice (GCP) guidelines. Familiarity with clinical trial management systems, electronic data capture (EDC) tools, and protocol documentation is typically required. Strong attention to detail, organizational skills, and effective communication are vital soft skills for coordinating with research teams and ensuring regulatory compliance. These skills and qualities are crucial for maintaining patient safety, data integrity, and adherence to study protocols during weekend trial operations.

What are some unique challenges of working as a Weekend Clinical Trial RN, and how can I prepare for them?

As a Weekend Clinical Trial RN, you may encounter challenges such as limited onsite support, managing urgent protocol issues, and balancing patient care with strict research timelines. Since weekends often have fewer staff members present, strong communication and problem-solving skills are essential. To prepare, familiarize yourself with study protocols in advance, establish clear lines of communication with the principal investigator and other team members, and ensure you are comfortable with electronic data capture systems. Being proactive and organized will help you provide excellent patient care while maintaining compliance with research requirements.

What are Weekend Clinical Trial RNs?

Weekend Clinical Trial RNs are registered nurses who work primarily on weekends to support clinical research studies. Their responsibilities include administering investigational treatments, monitoring patient safety, collecting data, and ensuring protocol compliance. They collaborate with research teams, patients, and other healthcare providers to facilitate trials and maintain high standards of care. This role is crucial for studies that require continuous patient oversight and data collection outside of standard weekday hours.

What is the difference between Weekend Clinical Trial Rn vs Weekend Research Nurse?

AspectWeekend Clinical Trial RnWeekend Research Nurse
CredentialsRegistered Nurse (RN) license, clinical trial trainingRegistered Nurse (RN) license, research-specific training
Work EnvironmentClinical trial sites, hospitals, research facilitiesResearch centers, hospitals, clinical research units
Employer & IndustryPharmaceutical companies, research organizationsAcademic institutions, research organizations
Work ScheduleWeekend shifts, flexible hoursWeekend shifts, flexible hours

Both roles involve RN credentials and work in research settings, often during weekends. The main difference lies in the focus: Weekend Clinical Trial Rns primarily support clinical trial protocols, while Weekend Research Nurses may be involved in broader research activities. Both roles are essential in advancing clinical research and typically require similar certifications and work environments.

More about Weekend Clinical Trial Rn jobs
What cities are hiring for Weekend Clinical Trial Rn jobs? Cities with the most Weekend Clinical Trial Rn job openings:
What are the most commonly searched types of Clinical Trial Rn jobs? The most popular types of Clinical Trial Rn jobs are:
What states have the most Weekend Clinical Trial Rn jobs? States with the most job openings for Weekend Clinical Trial Rn jobs include:
Infographic showing various Weekend Clinical Trial Rn job openings in the United States as of May 2026, with employment types broken down into 1% Locum Tenens, 4% As Needed, 93% Full Time, 1% Part Time, and 1% Temporary. Highlights an 96% Physical, and 4% Remote job distribution, with an average salary of $130,034 per year, or $62.5 per hour.

$130K - $150K/yr

Full-time

Medical, Dental, Vision, Life, Retirement

Posted 18 days ago


Job description

Join Immatics and shape the future of cancer immunotherapy; one patient at a time!
Immatics is committed to making a meaningful impact on the lives of patients with cancer. We are the global leader in precision targeting of PRAME, a target expressed in more than 50 cancers. Our cutting-edge science and robust clinical pipeline form the broadest PRAME franchise with the most PRAME indications and modalities, spanning TCR T-cell therapies and TCR bispecifics.
Why Join Us?
  • Innovative Environment: Help to pioneer advancements in cancer immunotherapy.

  • Collaborative Culture: Be part of a diverse team dedicated to your professional growth.

  • Global Impact: Contribute to therapies that make a lasting impact on patients globally.

Role Overview:
We are seeking a Clinical Trial Manager (CTM) to support our U.S. Clinical Operations team. The CTM will oversee site management, monitoring oversight, and clinical trial operations activities to ensure compliance with GCP, regulatory requirements, and company SOPs. In this role, you will work closely with cross-functional teams and clinical sites to drive study execution, site engagement, and operational excellence across clinical trials.
Reports to: Associate Director, Team Lead Site Operations
Location: Fully Remote
Salary Range: $130,000 - $150,000
Basic Qualifications:
  • Bachelor's degree in life sciences, nursing, or a related field

  • 2+ years of experience in on-site clinical monitoring and 2+ years of Clinical Trial Manager experience within the pharmaceutical or biotechnology industry

  • Strong knowledge of ICH-GCP, FDA, EMA, and applicable clinical trial regulations

  • Demonstrated experience managing clinical trial sites, monitoring activities, and regulatory documentation

  • Proficiency with clinical trial systems and tools (e.g., CTMS, eTMF, Microsoft Office)

Preferred Qualifications:
  • Experience in oncology clinical trials or related therapeutic areas

  • Advanced ability to manage complex clinical operations processes and drive operational improvements

  • Experience leading training initiatives for CRAs and clinical trial sites

  • Demonstrated ability to drive quality, efficiency, and milestone achievement in fast-paced clinical environments

  • Experience contributing to process harmonization, innovation, and continuous improvement initiatives

  • Strong presentation, organizational, and cross-functional stakeholder management skills

In this role you will:
  • Partner with Clinical Operations leadership to support clinical trial execution and monitoring activities in alignment with project goals

  • Lead site feasibility, selection, initiation, and greenlight activities for clinical trial sites

  • Develop and maintain study-specific operational plans, training materials, and monitoring documentation

  • Oversee site management activities, including site engagement, regulatory submissions, and monitoring oversight

  • Review trial progress, patient recruitment, and data quality metrics, and implement actions to support study objectives

  • Provide guidance and oversight to CRAs, including trip report review and training support

  • Manage protocol and GCP deviations and contribute to continuous improvement of clinical operations processes and procedures

Travel required: up to 50% travel required, domestically and internationally.
Qualified candidates will participate in a structured interview process, which includes:
  • An initial recruiter phone screen (conducted via video)

  • A recruiter-facilitated introduction and interview with the hiring leader and key stakeholders (via video)

  • A final-stage interview, which may include an in-person meeting at our U.S. Headquarters in Houston, TX

What do we offer?
At Immatics, we believe in investing in our team's health, safety and well-being. Here's what you can expect if you join Immatics
Comprehensive Benefits:
  • Competitive rates for Health, Dental, and Vision Insurance

  • 4 weeks of vacation, granted up front each year and prorated for first and last year of employment.

  • 12 company paid holidays

  • 7 days of sick time

  • 100% employer-paid life insurance up to at 1x annual salary, up to one hundred thousand dollars

  • 100% employer-paid short- and long-Term disability coverage

  • 401(k) with immediate eligibility and company match...

  • The company will match 100% of your contributions up to 3% of your base salary for the first two years of employment, 4% for years 2-3 of employment, and up to 5% of your salary from the fourth year onward of continued employment.

  • Partially paid parental leave for eligible employees.

  • Additional voluntary employee-paid benefits and services, including accident, hospital indemnity, and critical illness insurance, as well as identity theft protection and pet insurance.

Equal Employment Opportunity
We are an equal opportunity employer and are committed to building a diverse and inclusive workplace. We consider all qualified applicants for employment without regard to race, color, religion, sex (including pregnancy, childbirth, or related medical conditions), sexual orientation, gender identity or expression, national origin, ancestry, age, marital status, disability, genetic information, veteran status, or any other status protected by applicable law.
Reasonable Accommodations
We are committed to providing reasonable accommodations to individuals with disabilities and to applicants with sincerely held religious beliefs, practices, or observances. If you require assistance or accommodation during the application or interview process, please contact us at RecruitingUS@immatics.com.