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Weekend Clinical Research Nurse Jobs (NOW HIRING)

Clinical Research Nurse

Champaign, IL · On-site

$66K - $92K/yr

JOB SUMMARY A Clinical Research Nurse is a member of the research team who serves participants in ... Occasional evening and weekend work may be required as job duties demand. The above statements are ...

Responsibilities Under the guidance and supervision of the Principal Investigator, the Research Nurse Specialist II (RNS II) is responsible for assuring that the integrity and quality of the clinical ...

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Weekend Clinical Research Nurse information

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$44

$62

How much do weekend clinical research nurse jobs pay per hour?

As of Sep 3, 2026, the average hourly pay for weekend clinical research nurse in the United States is $44.13, according to ZipRecruiter salary data. Most workers in this role earn between $36.30 and $52.40 per hour, depending on experience, location, and employer.

What is a weekend clinical research nurse?

Weekend Clinical Research Nurses are registered nurses who specialize in supporting clinical research studies during weekend hours. They are responsible for tasks such as administering investigational drugs, monitoring patients, collecting data, and ensuring protocol compliance. These nurses work closely with research teams to maintain the integrity of clinical trials and ensure participant safety outside of typical weekday schedules.

What are the key skills and qualifications needed to thrive as a weekend clinical research nurse, and why are they important?

To thrive as a Weekend Clinical Research Nurse, you need a registered nursing license, strong clinical skills, and experience in clinical research protocols. Familiarity with electronic data capture systems, Good Clinical Practice (GCP) certification, and knowledge of regulatory compliance is typically required. Excellent organizational skills, attention to detail, and effective communication are crucial soft skills for managing study participants and collaborating with research teams. These competencies ensure the integrity of research data, patient safety, and smooth study operations during weekend hours.

What are some common challenges faced by weekend clinical research nurses, and how can they be managed?

Weekend Clinical Research Nurses often navigate unique challenges such as coordinating with limited on-site staff, ensuring protocol adherence during off-hours, and maintaining effective communication with the broader research team. Managing these challenges typically involves thorough preparation, clear documentation of patient interactions, and proactive communication with investigators and coordinators. Utilizing detailed handover notes and embracing technology for real-time updates can also help ensure continuity of care and study compliance. Building strong relationships with both clinical and research staff is key to effectively addressing any issues that arise during weekend shifts.

What is the difference between Weekend Clinical Research Nurse vs Weekend Medical Assistant?

AspectWeekend Clinical Research NurseWeekend Medical Assistant
CredentialsRegistered Nurse (RN) license, clinical research trainingCertified Medical Assistant (CMA) or similar certification
Work EnvironmentResearch facilities, hospitals, clinics involved in clinical trialsDoctor's offices, outpatient clinics, hospitals
Employer & IndustryPharmaceutical companies, research institutions, hospitalsMedical practices, outpatient clinics, hospitals
Job FocusMonitoring clinical trial participants, data collection, patient care in research settingsAssisting with patient exams, taking vital signs, administrative tasks

The Weekend Clinical Research Nurse primarily focuses on supporting clinical trials, requiring RN licensure and research training, working mainly in research settings. In contrast, the Weekend Medical Assistant provides general patient support in clinical environments, with certification as a CMA or similar. Both roles are essential in healthcare but serve different functions and work environments.

More about Weekend Clinical Research Nurse jobs

What cities are hiring for Weekend Clinical Research Nurse jobs?

Cities with the most Weekend Clinical Research Nurse job openings:

What are the most commonly searched types of Clinical Research Nurse jobs?

The most popular types of Clinical Research Nurse jobs are:

What states have the most Weekend Clinical Research Nurse jobs?

States with the most job openings for Weekend Clinical Research Nurse jobs include:

Infographic showing various Weekend Clinical Research Nurse job openings in the United States as of August 2026, with employment types broken down into 3% As Needed, 71% Full Time, 18% Part Time, and 8% Contract. Highlights an 95% Physical, 1% Hybrid, and 4% Remote job distribution, with an average salary of $91,797 per year, or $44.1 per hour.

Full-time

Medical, Dental, Vision, Retirement, PTO

Re-posted 18 days ago


TriHealth rating

7.5

Company rating: 7.5 out of 10

Based on 176 frontline employees who took The Breakroom Quiz

232nd of 898 rated healthcare providers


Job description

***Clinical Research Nurse - Hatton Research - TriHealth Hatton Research Institute Make a difference every day as a Registered Nurse at TriHealth Hatton Research Institute. Join a compassionate, servant-led team committed to excellence in patient care while working in a supportive, high-energy environment. We offer career growth opportunities, and a comprehensive benefits package.

Apply today and grow your career with a team that truly values you. Location: Good Samaritan Hospital at 375 Dixmyth Avenue Work Schedule: Full-Time (80 hours bi-weekly) Day shift No weekends or holidays Incentives & Benefits: Comprehensive benefits package, including medical, dental, vision, paid time off, retirement plans, and tuition reimbursement. Please view our benefits page https://careers.trihealth.com/what-we-offer/benefits Job Requirements: Bachelor's Degree - Nursing (Required) 2 - 3 years' experience in Clinical Nursing Critical Thinking (Required) Proficient in Microsoft Office programs Knowledge of clinical research Registered Nurse Upon Hire Required Basic Life Support (BLS) Upon Hire Required Job Overview: Acts as the clinical research nurse for research studies in which TriHealth participates

Acts as a liaison between Study Sponsors, Study Monitors, Principal Investigators, other physicians, hospital staff, and the Institutional Review Board (IRB) to coordinate the efforts necessary to efficiently and effectively conduct a clinical research study. Actively participate in the selection of studies TriHealth conducts, developing a process for implementation of the protocol, participating in the identification of potential subjects, participating in the informed consent process, enrolling subjects and accurately and thoroughly collecting and reporting data. Educates and coordinates the care of patients who are on research studies.

Staff in this position can work at all sites where research is conducted within TriHealth. Travel between sites may be required. Staff in this position may be required to work in other research specialties other than the one for which they are hired.

Staff in this position must be available to cover the needs of the department, which may be 7am-7pm. Staffing needs and hours are determined by amount and kind of studies the department has at any given time. Job Responsibilities: Demonstrates the ability to develop processes to facilitate implementation of the research protocol to provide effective and safe medical research to all subjects.

Demonstrates the ability to identify potential and/or actual issues, which may prohibit the accurate implementation of the research protocol and initiate interventions to avoid protocol violations and/or unsafe practice. Demonstrates the ability to coordinate necessary activities between the Study Coordinators and the Principal Investigator. Performs initial and ongoing assessments of research subjects and implements care directed towards optimal outcomes.

Plans care for research subjects/families based on assessment, standards of care, optimal outcomes and protocol requirements. Implements and evaluates plan of care. Performs technical skills according to policy and procedure and accepts TriHealth Standards.

Documents in medical records appropriately. Comply with all IRB/FDA requirements in study submissions. Assures compliance with IRB/FDA standards and deadlines in notification of subject randomization and enrollment.

Assures compliance with IRB/FDA standards and deadlines in completing Progress Reports. Assures compliance with IRB/FDA standards and deadlines in reporting all deaths and adverse events within study subjects. Assures compliance with IRB/FDA standards and deadlines in facilitating communication between study sponsor and designated IRB.

Appropriately and accurately assesses potential subjects for inclusion and exclusion criteria. Keeps Case Report Forms complete and thorough using the IRB and FDA standards. Supports hospital staff in complying with research protocols and works to minimize the impact on their workload.

Keeps queries and protocol violations that can be controlled to a minimum. Responds appropriately and accurately to all queries in a timely fashion. Demonstrates knowledge of available studies, screening potential patients for eligibility, guiding physicians and staff in needed timetables for appropriate randomization.

Participates in the identification and selection of good clinical protocols based on subject selection, safe medical practice and resource availability. Attends training required by sponsoring organizations for specific protocols and/or attends meetings related to the initiation or on-going progress of a sponsored clinical trial. Acts as the point person for audit staff coming into institution for a review prepares a written response with a plan of action to any major/minor deficiencies.

Working Conditions: Bending - Rarely Climbing - Rarely Concentrating - Frequently Continuous Learning - Frequently Hearing: Conversation - Consistently Hearing: Other Sounds - Frequently Interpersonal Communication - Consistently Kneeling - Occasionally Lifting <10 Lbs. - Occasionally Lifting 50+ Lbs. - Rarely Lifting <50 Lbs.

- Rarely Pulling - Occasionally Pushing - Occasionally Reaching - Frequently Reading - Frequently Sitting - Frequently Standing - Frequently Stooping - Consistently Talking - Frequently Thinking/Reasoning - Consistently Use of Hands - Frequently Color Vision - Occasionally Visual Acuity: Far - Consistently Visual Acuity: Near - Consistently Walking - Frequently TriHealth SERVE Standards and ALWAYS Behaviors: At TriHealth, we believe there is no responsibility more important than to SERVE our patients, our communities, and our fellow team members. To achieve our vision and mission, ALL TriHealth team members are expected to demonstrate and live the following: Serve: ALWAYS... Welcome everyone by making eye contact, greeting with a smile, and saying "hello" Acknowledge when patients/guests are lost and escort them to their destination or find someone who can assist Refrain from using cell phones for personal reasons in public spaces or patient care areas Excel: ALWAYS..

Recognize and take personal responsibility to address and recover from service breakdowns when a customer's expectations have not been met Offer patients and guests priority when waiting (lines, elevators) Work on improving quality, safety, and service Respect: ALWAYS... Respect cultural and spiritual differences and honor individual preferences. Respect everyone's opinion and contribution, regardless of title/role

Speak positively about my team members and other departments in front of patients and guests. Value: ALWAYS... Value the time of others by striving to be on time, prepared and actively participating

Pick up trash, ensuring the physical environment is clean and safe. Be a good steward of our resources, using supplies and equipment efficiently and effectively, and will look for ways to avoid waste. Engage: ALWAYS..

Acknowledge wins and frequently thank team members and others for contributions. Show courtesy and compassion with customers, team members and the community Job Keywords: Clinical Research, Research, Registered Nurse, Nurse Apply Apply (Existing Employee)


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About TriHealth

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TriHealth provides unique opportunities from across disciplines in many different aspects including patient care, care coordination, education and management. We are unique because we know that team members who focus on our mission and values provide excellent patient care.

Industry

Health care and social assistance

Company size

10,000+ Employees

Headquarters location

Cincinnati, OH, US

Year founded

1995