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The Vice President, Genome Technologies is responsible for providing scientific, strategic and operational leadership for the New York Genome Center’s genome technology enterprise, encompassing high-throughput research sequencing, single-cell and spatial genomics, emerging multiomic technologies, laboratory automation, and technology innovation. This person will lead NYGC’s genome technology strategy and operations, integrating cutting‑edge innovation with large‑scale, high‑throughput execution to enable transformative, collaborative science.

The Vice President will develop and execute a long-term technology strategy that positions NYGC at the forefront of genome science while ensuring operational excellence in support of large-scale collaborative research, institutional initiatives, and externally funded programs. As a recognized scientific leader, the Vice President will contribute intellectually to the Center's research direction, foster strategic partnerships, and lead the development of innovative genomic technologies and research programs.

Working closely with the Scientific Director & CEO and other executive leaders, the Vice President will shape NYGC's scientific priorities, expand its national research portfolio, cultivate collaborations with academic, clinical, government, and industry partners, and help establish NYGC as a global leader in genome technologies and AI-enabled genomic research.

This position serves as a member of the Executive Management Team and oversees the Center's Genome Technologies organization, including research sequencing, technology development, project management, laboratory operations, and associated scientific support functions.

Responsibilities

• Provides scientific leadership and technical expertise to shape major institutional initiatives, partnerships, and collaborative research programs;
• Serves as a scientific thought partner in defining NYGC’s research direction, including emerging opportunities in genomics, sequencing technologies, and large‑scale data generation;
• Builds and sustains multi‑institutional collaborations with academia, healthcare systems, nonprofit organizations, and industry;
• Plays a central role in developing and leading NIH and other grant applications, serving as Principal Investigator (PI) or Co‑PI on major proposals;
• Represents the Center externally as a scientific leader to the genomics community, including NIH, other funding agencies, and key partners;
• Contributes to the development of consortia, partnerships, and collaborative research programs that expand NYGC’s scientific and funding footprint;
• Advances a strategy focused on collaborative science and funded research, complementing service‑based sequencing activities;
• Develops a multi‑year technology roadmap that anticipates emerging scientific opportunities and positions NYGC as a leader in genome technologies;
• Identifies, evaluates, and implements transformative technologies spanning sequencing, single‑cell, spatial, long‑read, genome engineering, multiomic, and future genomic platforms;
• Establishes strategic partnerships with biotechnology companies to provide NYGC investigators and collaborators with early access to emerging technologies;
• Partners closely with computational scientists and AI researchers to develop datasets and technology platforms that accelerate AI‑enabled genome interpretation and biological discovery;
• Partners closely with NYGC faculty to align technology development with investigator‑initiated science and institutional priorities, ensuring strong integration between platform capabilities and internal research programs;
• Promotes high‑impact collaborative publications that showcase NYGC's scientific and technological leadership.

Research Operations Strategy and Execution

• Provides scientific and operational leadership for NYGC's genome technology platforms, ensuring they remain at the forefront of scientific innovation and support the Center's evolving research priorities;
• Oversees technology evaluation, validation, implementation, and lifecycle management across all research platforms;
• Ensures technology platforms are scalable, reproducible, cost‑effective, and capable of supporting large collaborative projects;
• Works closely with NYGC faculty to translate emerging biological questions into innovative technology solutions;
• Leads development of programs involving our Institutional Founding Members (IFMs), hospitals, and research collaborators.

Operational Oversight

• Develops annual operating and capital budgets for Genome Technologies;
• Oversees strategic investments in instrumentation, automation, laboratory infrastructure, and technology platforms;
• Establishes operational metrics and quality indicators to ensure scientific excellence, efficiency, and customer satisfaction;
• Accountable for execution of sequencing operations in support of scientifically driven projects and grants;
• Oversees prioritization and delivery of research projects, ensuring alignment with grant commitments and scientific objectives;
• Drives improvements in efficiency, scalability, and quality of sequencing operations;
• Oversees adoption and implementation of new sequencing technologies and methodologies;
• Provides deep expertise in next‑generation sequencing (NGS) and related technologies;
• Optimizes laboratory capacity, resource allocation, and operational workflows to maximize efficiency, meet project timelines, and support institutional research priorities;
• Partners with Finance to develop and maintain sustainable pricing and cost‑recovery models for genomics services;
• Monitors external market trends, competitive genomics capabilities, and emerging technologies to inform strategic planning and maintain operational excellence;
• Negotiates strategic agreements with technology vendors, suppliers, and external partners to optimize cost, service quality, and access to innovative genomic technologies.

Grant Development and Research Funding

• Plays a leading role in expanding NYGC’s grant portfolio, particularly NIH and large‑scale collaborative funding;
• Contributes to and helps lead the Grant Development Group with scientific vision and strategic insight;
• Provides leadership across all phases of proposal development, especially for multi‑PI, center, and consortium grants;
• Works closely with Research Administration to ensure high‑quality, competitive submissions;
• Helps build sustainable funding streams through programmatic, consortium‑based, and investigator‑initiated grants;
• Represents NYGC in settings that advance funding, partnerships, and scientific visibility;
• Identifies new strategic funding opportunities involving technology development, large‑scale collaborative genomics, and national research infrastructure;
• Develops programmatic initiatives that generate sustainable external funding while advancing NYGC's long‑term scientific mission.

Team Leadership and Scientific Culture

The Vice President will recruit, develop, and inspire an exceptional multidisciplinary team of scientists, engineers, laboratory leaders, project managers, and operational professionals dedicated to advancing genome science.

• Building a culture of scientific rigor, innovation, collaboration, and continuous improvement;
• Recruiting outstanding scientific and operational talent;
• Developing future scientific leaders through mentoring, coaching, and succession planning;
• Promoting collaboration across research, informatics, AI, operations, and clinical genomics;
• Creating an inclusive, mission‑driven organization focused on scientific excellence.

Technology Innovation

• Develops and implements the Center's technology innovation strategy;
• Evaluates emerging technologies and establishes pilot programs;
• Partners with faculty to develop novel experimental platforms;
• Builds collaborations with technology companies to accelerate innovation;
• Positions NYGC as an early adopter and national demonstration site for next‑generation genomic technologies.

Requirements

• PhD or MD or MD/PhD required with strong scientific credentials;
• An internationally recognized scientific leader with an outstanding record of innovation in genomics, genome technologies, or related disciplines;
• Demonstrated ability to translate scientific vision into scalable, high‑throughput operations, including oversight of large‑scale sequencing production, cost optimization, and delivery against project timelines;
• Demonstrated success leading large multidisciplinary scientific organizations and complex collaborative research programs, including serving as PI or Co‑PI on externally funded research programs (e.g., NIH grants);
• Established record of high‑impact scientific publications;
• Demonstrated success developing strategic partnerships with academic institutions, government agencies, and industry;
• Experience managing multimillion‑dollar scientific programs and operating budgets;
• Demonstrated ability to translate emerging technologies into scalable research platforms;
• Deep knowledge of next‑generation sequencing technologies and genomic analysis;
• 10+ years of management experience with a strong commitment to developing teams;
• Exceptional ability to bridge scientific vision with operational execution;
• Strong communication, collaboration, and influencing skills across scientific and administrative stakeholders;
• Ability to thrive in a dynamic, evolving, and research‑driven environment.

Don’t meet every single requirement? At NYGC we are dedicated to building a diverse, inclusive, and authentic workplace, so if you’re excited about this role but your past experience doesn’t align perfectly with every qualification in the job description, we encourage you to apply anyway. You may be just the right candidate for this or other roles.

Competencies

• Strategic Leadership. Develops a compelling long‑term vision and translates scientific opportunities into organizational priorities. Makes sound decisions in rapidly evolving scientific environments. Balances innovation with operational excellence and financial stewardship.
• Technical and Professional Skills: Consistently demonstrates skills and knowledge relevant for current role; strives to expand the depth and breadth of technical and professional skills; works with a high level of integrity; exhibits focus and discipline; appropriately prioritizes, manages expectations and delivers on commitments.
• Collaborative & Communicative: Models collaboration and teamwork; brings out the best in others; effectively works with all levels, internally and externally; respects and embraces diversity of perspective; communicates clearly and listens carefully; uses good judgment as to what to communicate and when to do so.
• Adaptable & Innovative: Adaptable and embraces change; develops new insights and pursues improvements and efficiency; fosters exchange of new ideas and willingness to challenge the status quo; takes initiative and is solution‑oriented; engages in work with passion and curiosity.
• Leader and Manager: Attracts, develops and retains diverse talent to achieve outstanding results; encourages professional development, coaches and regularly communicates expectations and feedback; aligns and inspires efforts toward our mission; translates organizational vision into action; responsibly utilizes NYGC’s human and financial resources to ensure organizational and financial health; uses good judgment when making decisions; pushes boundaries and generates new ideas.

Work Location & Leadership Presence

NYGC recognizes the value of workplace flexibility while fostering a highly collaborative, team‑oriented scientific environment. As a member of the Executive Management Team, the Vice President, Genome Technologies is expected to maintain a regular on‑site presence to provide visible leadership, strengthen collaboration, and support organizational culture.

The successful candidate is expected to work on‑site at least four (4) days per week, with limited remote work flexibility subject to approval by the Scientific Director & CEO. Regular interaction with faculty, staff, institutional partners, and executive leadership is essential to the success of this role. Occasional evening and weekend work, as well as domestic and international travel, may be required.

Salary & Benefits

The pay range for this position is $270,000-350,000 per year; the base pay offered may vary depending on job‑related knowledge, skills, and experience.

In addition, NYGC offers a full range of medical, financial, and other benefits as well as generous time off. This includes Medical/Dental/Vision for employees & dependent(s); Vacation, Holidays, Sick, and Other Leave, including a paid winter break; a 401(k) match; Life Insurance; Flexible Spending Accounts; employee Tuition Reimbursement; flexible schedules and telework options for some positions; an Employee Assistance Program; and much more.

About the New York Genome Center

The New York Genome Center (NYGC) is an independent, nonprofit, academic research organization dedicated to advancing genomic research. NYGC scientists and staff are furthering new approaches to diagnosing and treating neurological diseases and cancer through their unique capabilities in whole genome sequencing, RNA sequencing, state‑of‑the‑art analytics, and the development of genomic tools. NYGC concentrates specifically on disease‑based research in the following areas: neuropsychiatric disease (autism, schizophrenia, bipolar); neurodegenerative disease (ALS, Alzheimer’s, Parkinson’s, Huntington’s), and cancer.

Located in Lower Manhattan, the New York Genome Center was founded by and remains closely affiliated with the leading academic medical centers and research universities in the New York region, engaging in research projects with and for these institutions. Essential to our collaborative work is an outstanding faculty, whose members typically hold a joint appointment at NYGC and a partner university. They support our scientific mission by conducting independent research in areas of mutual interest to us and the wider scientific community.