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Vc Operating Partner Jobs in Massachusetts (NOW HIRING)

... the operating system for scientific intelligence. We are fundamentally reimagining and ... Underscore_VC, global juggernaut Insight Partners, and Impetus Ventures (the CEO's fund). In ...

... for operators to manage and optimize it, all from one central location. HqO has been trusted to ... Partner with Sales to own the end-to-end customer lifecycle, including onboarding, adoption ...

... for operators to manage and optimize it, all from one central location. HqO has been trusted to ... Partner with Sales to own the end-to-end customer lifecycle, including onboarding, adoption ...

... VC professionals. We believe our best work happens when we're together. AV operates as a 5-day-a ... The Director partners with managers to translate feedback into practical Individual Development ...

... VC professionals. We believe our best work happens when we're together. AV operates as a 5-day-a ... The Director partners with managers to translate feedback into practical Individual Development ...

Showing results 21-40

Vc Operating Partner information

See Massachusetts salary details

$33.3K

$128.3K

How much do vc operating partner jobs pay per year?

As of Aug 18, 2026, the average yearly pay for vc operating partner in Massachusetts is $123,524.00, according to ZipRecruiter salary data. Most workers in this role earn between $127,200.00 and $127,200.00 per year, depending on experience, location, and employer.

What is a VC Operating Partner?

VC Operating Partners are experienced executives who work within venture capital (VC) firms to support portfolio companies with operational expertise. Unlike traditional investors, they focus on helping startups scale by offering guidance on strategy, operations, recruiting, and growth. Their hands-on approach helps companies address challenges and seize opportunities more effectively, adding value beyond just financial investment. Operating Partners often have backgrounds in management, entrepreneurship, or specific industries relevant to the VC firm's focus.

How does a VC Operating Partner typically collaborate with portfolio companies to drive growth?

A VC Operating Partner works closely with portfolio company leadership teams, offering strategic guidance and hands-on operational support tailored to each company's needs. This often involves helping to refine business models, optimize go-to-market strategies, recruit key executives, and implement best practices in areas such as sales, marketing, and product development. The role requires balancing advisory input with actionable execution, while building strong relationships to earn the trust of founders and management teams. Collaboration is frequent and may include structured check-ins, on-site visits, and ongoing communication to ensure alignment and measurable progress.

What are the key skills and qualifications needed to thrive as a VC Operating Partner, and why are they important?

To thrive as a VC Operating Partner, you need extensive experience in business operations, strategic management, and scaled execution, often demonstrated by a track record in C-suite roles or successful entrepreneurship. Familiarity with financial modeling, portfolio management systems, and due diligence processes, along with an understanding of industry-specific metrics, is typically required. Exceptional leadership, communication, and mentoring skills distinguish top performers by enabling strong relationships with founders and portfolio companies. These abilities are crucial for driving growth, supporting investment success, and maximizing value creation within the venture capital ecosystem.

What is the difference between Vc Operating Partner vs Vc Associate?

AspectVc Operating PartnerVc Associate
Required CredentialsExperience in operations, industry expertise, often MBA or similarUndergraduate degree, some finance or business background
Work EnvironmentHands-on operational involvement, strategic guidanceResearch, due diligence, financial analysis
Employer & Industry UsagePrivate equity firms, venture capital firmsVenture capital firms, investment teams

The Vc Operating Partner typically has extensive operational experience and works closely with portfolio companies to improve performance. In contrast, a Vc Associate focuses on deal sourcing, due diligence, and supporting investment processes. While both roles are integral to venture capital firms, the Operating Partner is more involved in post-investment operational management, whereas the Associate is more involved in the early investment stages.

What are popular job titles related to Vc Operating Partner jobs in Massachusetts?

For Vc Operating Partner jobs in Massachusetts, the most frequently searched job titles are:

What job categories do people searching Vc Operating Partner jobs in Massachusetts look for?

The top searched job categories for Vc Operating Partner jobs in Massachusetts are:

What cities in Massachusetts are hiring for Vc Operating Partner jobs?

Cities in Massachusetts with the most Vc Operating Partner job openings:

Chief of Staff to the CEO

TetraScience

Boston, MA • On-site

Full-time

Life, Retirement, PTO

Re-posted 11 days ago


Job description

About TetraScience

TetraScience is the Scientific Data and AI Company and developer of the Tetra OS, the operating system for scientific intelligence. We are fundamentally reimagining and  replatforming science for the AI era. 

TetraScience's customers include many of the world's top biopharmaceutical firms; its growing ecosystem of strategic partners includes NVIDIA, Databricks, Thermo Fisher Scientific, Snowflake, Google, and Microsoft; and its venture capital backers include Boston-based Underscore_VC, global juggernaut Insight Partners, and Impetus Ventures (the CEO's fund). 

In connection with your candidacy, you will be asked to carefully review and internalize  "The Tetra Way" and "Unvarnished," each authored by our CEO, Patrick Grady. 

It is impossible to overstate the importance of these essays, and you should take  them literally as you decide whether our mission, culture, and expectations are right for you.

Everything you will need to understand about working at TetraScience, and for Patrick, can be found in these writings.

The Opportunity

The Chief of Staff to the CEO is a high-trust, internal and external role for a scientist-business athlete who wants to operate at the center of TetraScience's relationships with global customers, market-leading partners, and government agencies. 

The role requires a fluid schedule, rapid responsiveness, and the ability to travel as needed to support CEO priorities. The role necessitates high clock speed, high bandwidth, insatiable curiosity, authentic humility, and continuous collaboration. 

You will help Patrick focus on the few conversations that truly matter, then turn those conversations into structured follow-through that moves alliances, programs, and contracts from idea to impact.

This is an ideal role for someone who enjoys working behind the scenes but at the center of what's next in scientific data, AI, and policy-equally comfortable in a pharma boardroom, with a hyperscaler account team, or across the table from senior public-sector leaders.

What You Will Do

Amplify the CEO in the market

  • Coordinate and support Patrick's engagement with executives at biopharma companies, major technology partners, and key government agencies and consortia.
  • Prepare briefing materials, talking points, and post-meeting summaries that capture objectives, decisions, and next steps for every high-stakes interaction.

Own follow-through on critical relationships

  • Turn meeting notes, emails, and Zoom discussions into clear action plans with owners, deadlines, and measures of success-and ensure they are executed.
  • Track progress on strategic accounts, alliances, and public-sector initiatives, surfacing risks and opportunities early so Patrick can intervene where he adds the most leverage.

Connect science, business, and policy narratives

  • Help craft compelling, concise narratives and materials for senior audiences on themes such as Scientific AI, the value of industrialized scientific data, and sovereign scientific AI.
  • Synthesize input from scientists, commercial leaders, policymakers, and investors into options and recommendations that support CEO-level decision-making.

Support a disciplined operating rhythm around the CEO

  • Collaborate with Patrick and his executive team to maintain a simple, effective operating cadence that aligns Patrick's time with TetraScience's most important priorities.
  • Protect his schedule and attention, streamline information flow, and ensure he always walks into critical conversations fully prepared.

Requirements

Who You Are

Scientifically fluent, commercially committed, and outcomes oriented.  

  • Advanced training in a life sciences discipline (MS or PhD required), plus meaningful exposure to business, strategy, or policy (e.g., consulting, banking, corporate development, VC, or senior operating roles in science-driven organizations).
  • Comfortable engaging credibly with R&D leaders, business executives, and public-sector stakeholders on topics that span science, economics, and regulation.

High-judgment operator with range

  • Proven ability to manage complex, multi-stakeholder workstreams with a mix of structure, urgency, and calm under pressure, thriving in a fast-paced, often ambiguous environment.
  • Willing and able to maintain a flexible schedule, respond quickly to emerging priorities, and travel in support of CEO and company needs.
  • Exceptional written and verbal communication skills; you can move seamlessly from a quick email recap to a polished deck or memo for a Csuite or agency audience.

Low-ego, high-standards teammate

  • Drawn to doing the unglamorous but essential work-note-taking, follow-ups, logistics, synthesis-that makes high-profile outcomes possible.
  • Known for humility, discretion, and trustworthiness; you handle sensitive information and relationships with care.

Aligned with The Tetra Way

  • Motivated by a mission with real stakes for patients and society, and energized by working in an elite, high-feedback, high-accountability environment.
  • Willing to read, internalize, and live The Tetra Way-rigorous first principles thinking, radical transparency, and extreme ownership as non-negotiables.

Benefits

  • Competitive compensation
  • Stock options in a VC-backed Series C company
  • 100% employer-paid benefits for all eligible employees and immediate family members
  • 401(k)
  • Unlimited paid time off (PTO)
  • Flexible working arrangements
  • Company-paid Life Insurance, LTD/STD

The salary range for this position is $185,000-$250,000. The salary range posted reflects our target baseline for this role. Final compensation is determined by a thorough evaluation of factors including the candidate's specific experience, localized market data, and internal team equity.