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Upstream Process Scientist Jobs in Texas (NOW HIRING)

... processes for high-efficiency production of antigens and antibodies. We are headquartered in ... You'll work closely with project scientists, contributing to aseptic cell culture, transfection ...

... upstream and midstream oil and gas industry * Understanding of EPA and state air quality ... Knowledge of industrial process systems and environmental controls

We are a growing team of experienced scientists, engineers and entrepreneurs from the DTU, Stanford ... Optimize and debottleneck production processes, particularly gas fermentation and related upstream ...

Many of the world's top engineers and scientists come together in our Water business because they ... Advanced Manufacturing, Datacenters, Upstream and Downstream Oil and Gas, Chemical Processing ...

Many of the world's top engineers and scientists come together in our Water business because they ... Advanced Manufacturing, Datacenters, Upstream and Downstream Oil and Gas, Chemical Processing ...

Many of the world's top engineers and scientists come together in our Water business because they ... Advanced Manufacturing, Datacenters, Upstream and Downstream Oil and Gas, Chemical Processing ...

Many of the world's top engineers and scientists come together in our Water business because they ... Advanced Manufacturing, Datacenters, Upstream and Downstream Oil and Gas, Chemical Processing ...

... upstream process improvements. What you will likely bring: * 4-6 years' experience in billing ... Bachelor of Science degree, Bachelor of Business Administration degree, or equivalent experience.

Sr. Production Process Engineer

Texas City, TX · On-site

$89K - $115K/yr

We are a growing team of experienced scientists, engineers and entrepreneurs from the DTU, Stanford ... Optimize and debottleneck production processes, particularly gas fermentation and related upstream ...

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Upstream Process Scientist information

What is an upstream process scientist?

An Upstream Process Scientist is responsible for developing and optimizing the early stages of biopharmaceutical production, including cell culture, media preparation, and bioreactor operations. They work to improve cell growth, productivity, and scalability of biologics such as monoclonal antibodies or vaccines. Their role involves designing experiments, analyzing data, and troubleshooting issues to ensure efficient and reproducible upstream processes.

What does an upstream process scientist do?

As an Upstream Process Scientist, your daily responsibilities often include designing and executing experiments to optimize cell culture conditions, operating and monitoring bioreactors, and analyzing process data to improve yields or purity. You will collaborate closely with downstream process scientists, quality assurance teams, and manufacturing staff to ensure smooth technology transfer and troubleshoot production issues. Additionally, documenting findings, preparing technical reports, and participating in project meetings are key aspects of the role. This position is dynamic and may also involve scaling up processes from laboratory to pilot or manufacturing scale, providing excellent opportunities to develop both technical expertise and project management skills.

What skills and qualifications are needed to be an upstream process scientist?

To thrive as an Upstream Process Scientist, you need a strong background in bioprocess engineering, cell culture, fermentation, and a relevant scientific degree such as biotechnology, biology, or chemical engineering. Familiarity with bioreactors, process analytical technologies (PAT), statistical analysis software, and GMP/GLP standards is highly valued, and some positions may require certifications like Six Sigma or specific training in biomanufacturing. Excellent problem-solving, communication, and teamwork skills distinguish top performers in this role, as does the ability to adapt quickly to evolving project needs. These skills are essential for developing and optimizing scalable, high-yield biological production processes while ensuring regulatory compliance and effective collaboration across multidisciplinary teams.

What are the most commonly searched types of Upstream Process Scientist jobs in Texas?

The most popular types of Upstream Process Scientist jobs in Texas are:

What job categories do people searching Upstream Process Scientist jobs in Texas look for?

The top searched job categories for Upstream Process Scientist jobs in Texas are:

What cities in Texas are hiring for Upstream Process Scientist jobs?

Cities in Texas with the most Upstream Process Scientist job openings:

Infographic showing various Upstream Process Scientist job openings in Texas as of August 2026, with employment types broken down into 1% As Needed, 82% Full Time, 14% Part Time, 2% Contract, and 1% Nights. Highlights an 91% Physical, 3% Hybrid, and 6% Remote job distribution.

Upstream Associate

SIGNOBIO INC

Houston, TX • On-site

Full-time

Posted 20 days ago


Job description

About Us

Sino Biological is a world-renowned reagent supplier and contract research organization, listed on ChiNext of the Shenzhen Stock Exchange (301047 Sino Biological Inc.). Our core technology platform is an in-house-developed mammalian cell-based recombinant expression system that leverages proprietary reagents and processes for high-efficiency production of antigens and antibodies. We are headquartered in Beijing, China, with a U.S. base in the Greater Philadelphia area, an office and bioprocessing center in Houston, Texas, and subsidiaries in Frankfurt, Germany, and Kawasaki, Japan. Sino Biological is committed to providing high-quality recombinant protein and antibody reagents and to being a one-stop technical services shop for life science researchers worldwide. All of our products are independently developed and produced. In addition, we offer pharmaceutical companies and biotechnology firms pre-clinical production technology services for hundreds of monoclonal antibody drug candidates.


Job Description

This entry-level, hands-on role offers experience in both upstream bioprocessing and protein quality control (QC) for individuals looking to launch their industrial biotechnology career. As an Associate, Upstream, you’ll assist in recombinant protein and antibody expression using mammalian cell cultures, while also supporting QC testing to evaluate product quality. You’ll work closely with project scientists, contributing to aseptic cell culture, transfection, harvest, and analytical testing, all with an emphasis on accuracy, documentation, and collaboration across teams. Flexibility is key, including potential weekend work, early/late weekday shifts, and participation in essential lab maintenance or cross-functional support tasks as needed.


Responsibilities
  • Perform recombinant protein expression using mammalian systems such as HEK293 and CHO.

  • Execute upstream workflows including cell thawing, expansion, transfection, and harvesting.

  • Maintain lab cleanliness, including biosafety cabinets, incubators, and shared spaces.

  • Handle and maintain cell cultures using proper aseptic techniques.

  • Conduct protein quality control assays, including SDS-PAGE, HPLC-SEC, endotoxin testing, and UV-Vis measurements.

  • Record data and observations in electronic lab notebooks accurately and promptly.

  • Assist with media/reagent preparation, equipment setup, and maintenance tasks.

  • Support instrument calibration, troubleshooting, and lab upkeep.

  • Collaborate with downstream and cross-functional teams to ensure smooth project execution.

  • Conduct product aliquoting to meet delivery timelines.

  • Adhere to all safety and PPE protocols under federal, state, and local regulations.


Requirements
  • Bachelor’s degree (BA or BS) in Biology, Cell Biology, Biochemistry, Biotechnology, or a related field.

  • 0–3 years of lab experience with mammalian cell culture; HEK293 and CHO preferred.

  • Familiarity with suspension culture and aseptic techniques.

  • Basic experience with analytical assays such as SDS-PAGE, HPLC-SEC, UV-Vis, or endotoxin testing is a plus.

  • Strong attention to detail, documentation, and troubleshooting skills.

  • Flexible and adaptable to varying schedules or project demands.

  • Effective communication skills and the ability to work collaboratively in a team-oriented environment.

  • Must be able to lift and move 25–50 lbs as needed.


Why Join Us at C4B?

Working at Sino Biological’s C4B facility isn’t just another lab job, it’s a chance to be part of something bigger. Here are just a few of the unique benefits of our Houston site:

  • World-class location: Be part of the Texas Medical Center, the largest medical complex in the world, where biotech innovation thrives.

  • Beautiful work environment: Enjoy a brand-new, state-of-the-art facility designed for collaboration and scientific excellence.

  • Free onsite parking: Skip the hassle and expense of parking in the Medical Center, we’ve got you covered.

  • Free onsite gym: Stay active and energized with convenient access to fitness facilities right at work.

  • Career growth opportunities: Learn directly from industry professionals while growing your career at a global biotech company.

  • Supportive team culture: A welcoming, team-first workplace that values diversity, collaboration, and professional development.


Join Us in Advancing Scientific Innovation!

Be a part of Sino Biological and contribute to groundbreaking scientific advancements worldwide. Apply today to join our dynamic team!

Sino Biological is an equal opportunity employer. We celebrate diversity and are committed to creating an inclusive environment for all employees.


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