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Upstream Process Development Jobs in Houston, TX

Sino Biological US Inc.

R&D Senior Scientist

Houston, TX · On-site

$90K - $115K/yr

... processes for the efficient production of antigens and antibodies. With its main manufacturing ... Advise and review upstream expression workflows in mammalian and insect systems (HEK293, CHO, Sf9 ...

Whitley Penn

Accounting Manager, Oil & Gas

Houston, TX · On-site +1

Advanced technical skills and well-developed management and supervisory skills are required. The ... Develop tools, systems, and processes related to O&G Upstream accounting. * Develop comprehensive ...

New

Whitley Penn

Accounting Manager, Oil & Gas

Houston, TX · On-site

Advanced technical skills and well-developed management and supervisory skills are required. The ... Develop tools, systems, and processes related to O&G Upstream accounting. * Develop comprehensive ...

bp

Imaging Geophysicist

Houston, TX · On-site

The Seismic Technology team is part of bp's Upstream R&D responsible for driving innovations in ... Build proficiency with bp's seismic imaging technologies, proprietary processing toolkits ...

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Upstream Process Development information

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$18

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How much do upstream process development jobs pay per hour?

As of Jul 24, 2026, the average hourly pay for upstream process development in Houston, TX is $25.32, according to ZipRecruiter salary data. Most workers in this role earn between $22.50 and $26.63 per hour, depending on experience, location, and employer.

What jobs pay 500,000 a year in the US?

In the field of Upstream Process Development, senior roles such as Director or Vice President can reach or exceed $500,000 annually, especially with bonuses and stock options. These positions typically require extensive experience, advanced degrees, and leadership skills in biopharmaceutical or biotech industries. High compensation is often associated with managerial responsibilities, strategic decision-making, and overseeing large teams or projects.

What are the key skills and qualifications needed to thrive in Upstream Process Development, and why are they important?

Success in Upstream Process Development requires a strong background in biology, biochemistry, or chemical engineering, often with an advanced degree and experience in cell culture or fermentation techniques. Familiarity with bioreactors, process control systems, and analytical instrumentation, as well as knowledge of cGMP regulations, is essential. Critical thinking, problem-solving, and effective communication are important soft skills for optimizing processes and collaborating across multidisciplinary teams. These competencies ensure efficient development of scalable production processes, maintaining product quality and regulatory compliance.

What are common upstream jobs?

Common upstream process development jobs include roles such as upstream process scientist, bioprocess engineer, and fermentation scientist. These positions focus on developing and optimizing the early stages of biopharmaceutical production, often requiring knowledge of cell culture, bioreactor operation, and process scale-up. Skills in laboratory techniques, process analytical technology, and regulatory compliance are also important in these roles.

What biology jobs pay over $100k?

In upstream process development, senior roles such as Process Development Managers, Principal Scientists, and Regulatory Affairs Directors often have salaries exceeding $100,000. These positions typically require advanced degrees, extensive industry experience, and expertise in bioprocessing, quality control, or regulatory compliance.

What is the difference between Upstream Process Development vs Downstream Process Development?

AspectUpstream Process DevelopmentDownstream Process Development
FocusDevelopment of cell culture, fermentation, and bioreactor processesPurification, filtration, and formulation of bioproducts
Skills & CredentialsBioprocess engineering, molecular biology, biochemistryBioprocessing, chromatography, analytical chemistry
Work EnvironmentLaboratories, bioreactors, pilot plantsPurification facilities, labs, quality control
Industry UsageBiotech, pharmaceutical manufacturingBiotech, pharmaceutical manufacturing

Upstream Process Development focuses on creating and optimizing cell culture and fermentation processes to produce bioproducts. In contrast, Downstream Process Development involves purifying and finishing these products. Both roles are essential in biopharmaceutical manufacturing and require similar scientific backgrounds, but they specialize in different stages of bioprocessing.

What is upstream process development?

Upstream process development involves designing and optimizing the initial stages of biopharmaceutical production, such as cell culture and fermentation, to produce target biological products. It requires knowledge of bioprocessing, cell biology, and often involves working with bioreactors and process control systems to ensure consistent, high-quality output.

What are some common challenges faced in upstream process development and how do teams typically address them?

One of the main challenges in upstream process development is optimizing cell culture conditions to consistently achieve high yields and product quality. Teams often encounter variability in biological systems and must troubleshoot issues such as contamination, scale-up inconsistencies, or nutrient limitations. Collaboration with analytical, downstream, and quality teams is essential to identify root causes and implement solutions. Regular data review meetings, cross-functional problem-solving, and continuous process improvement are standard practices to ensure robust upstream processes.
What are popular job titles related to Upstream Process Development jobs in Houston, TX? For Upstream Process Development jobs in Houston, TX, the most frequently searched job titles are:
What job categories do people searching Upstream Process Development jobs in Houston, TX look for? The top searched job categories for Upstream Process Development jobs in Houston, TX are:
What cities near Houston, TX are hiring for Upstream Process Development jobs? Cities near Houston, TX with the most Upstream Process Development job openings:
Upstream Process Development jobs near you
Infographic showing various Upstream Process Development job openings in Houston, TX as of July 2026, with employment types broken down into 75% Full Time, and 25% Contract. Highlights an 100% In-person job distribution, with an average salary of $52,667 per year, or $25.3 per hour.
Process Improvement Specialist

Process Improvement Specialist

Comfort Systems USA

Houston, TX • On-site

Full-time

Posted 29 days ago

Comfort Systems USA rating

7.3

Company rating: 7.3 out of 10

Based on 74 frontline employees who took The Breakroom Quiz

120th of 242 rated repair and maintenance companies

Job description

POSITION OVERVIEW:
The Process Improvement Specialist plays a vital role in enhancing efficiency, quality, and productivity within our business processes.
KEY JOB RESPONSIBILITIES:
  • Process Analysis:
    • Collaborate with cross-functional teams to understand current processes.
    • Assemble, create and maintain detailed process maps.
    • Conduct a gap analysis to identify areas for improvement and recommend changes.
    • Use data analysis to identify trends and patterns.
    • Build cross-functional teams to address end-to-end comprehensive analyses to ensure any potential upstream/downstream impacts are accounted for.
    • Develop TAS process-map standard.
  • Process Improvement:
    • Working with department stakeholders, develop and implement process improvements to increase efficiency.
    • Create work instructions and standard operating procedures (SOPs).
    • Optimize workflows, reduce waste, and enhance productivity.
    • Ensure compliance with company policies and regulations.
    • Assist in the implementation of an employee driven, enterprise-wide Process Improvement program.
  • Training:
    • Develop training modules and materials tailored to specific processes.
    • Conduct interactive training sessions and workshops.
    • Identify and train SMEs in each functional unit to assist in implementation of change and ensure steady flow of incoming improvement suggestions.
    • Assess employee performance and provide feedback to management based on observations. Develop recommended training curriculums as needed for each department.
    • Update training materials based on process changes or improvements.
    • Maintain records of training activities and employee progress

Monitoring and Metrics:
  • Monitor the impact of process changes.
  • Facilitate process improvement workshops.
  • Assist in developing metrics and dashboards.
  • Any other duties assigned by TAS

JOB SKILLS:
  • Effective communication and interpersonal abilities to work collaboratively across departments.
  • Strong analytical skills with the ability to collect, interpret, and present data.
  • Excellent project management and organizational skills.
  • Change management expertise with the ability to lead and influence others.
  • Must be self-motivated and have ability to handle multiple and shifting priorities
  • Ability to work independently
  • Proficient in MS Office, MS Project, and database usage.

EDUCATION & TRAINING:
  • Bachelor's degree in Business Administration, Operations Management, Engineering, or a related field (Master's degree preferred).

MINIMUM REQUIREMENTS:
  • Proven experience in process improvement, business process reengineering, or related roles.
  • Proficiency in process improvement methodologies such as Lean, Six Sigma, or TQM.

PREFERRED REQUIREMENTS:
  • Extensive experience with ERP/MRP systems
  • Familiarity with process automation and technology solutions is a plus

PHYSICAL REQUIREMENTS/WORK ENVIRONMENT:
Position is at least 80% to 95% at a desk working with computer. Ability to exert up to 10 pounds of force occasionally and/or a negligible amount of force frequently or constantly to lift, carry, push, pull or otherwise move objects, including the human body. Performs other physical activities including use of fingers, sitting, stooping, bending, crouching, talking, hearing, and performing repetitive motions. Visual acuity requirements include color, depth perception and field of vision necessary to prepare and analyze data and figures, operate a computer terminal, and conduct extensive reading. The incumbent will be subject to inside environmental conditions.
COMPANY OVERVIEW:
Join a team driven to excel in all that we do! When you join TAS, you join a Houston-headquartered company that is part of a large Houston-headquartered publicly traded company, Comfort Systems USA, with a solid reputation built on outstanding value, integrity, and customer focus. We offer our customers and employees the best of both worlds: a small company feel with the resources, talent, process, and international reach of a large company.
TAS delivers innovative packaged modular systems that are engineered and manufactured in one of our Houston, TX facilities and utilized in data centers, power, and commercial/industrial utility system applications. TAS has successfully delivered and commissioned over 520 packages to over 33 countries. The company is headquartered in Houston, TX and has five ISO 9001 certified manufacturing facilities in Houston, encompassing 1.2m sq. feet with proximity to major shipping ports and interstate highways. TAS manages all logistics and transportation facilitating accelerated construction at customer's facilities.
TAS' fastest growing business is the data center market. By applying deep expertise in cooling, thermodynamics, and power, TAS has developed an entire product line that revolutionizes data center delivery.
With our tremendous market potential, advanced technological systems, entrepreneurial culture as well as a talented and productive workforce, we continue to set and exceed aggressive market penetration and financial goals. More information is available on the company website at: www.tas.com.
IMPORTANT NOTICE: TAS has a tobacco-free workplace policy, under which individuals are not allowed to smoke or use tobacco or nicotine products on the TAS premises, while conducting TAS business off premises or take "smoking" breaks during working hours. "smoking" and "tobacco or nicotine products" includes, but is not limited to, product such as cigarettes, e-cigarettes, cigars, pipes, vaping, all forms of smokeless tobacco (chewing tobacco, snuff, dip) and clove cigarettes
The above declarations are not intended to be an all-inclusive list of the duties and responsibilities of the job described, nor are they intended to be such a listing of the skills and abilities required to do the job. Rather, they are intended only to describe the general nature of the job.
Applications and resumes will be kept on file for a limited time and the Company is under no duty or obligation to contact applicants if they are not selected for the job applied for or if other jobs become available in the future. Applicants that desire to apply for a job that becomes available at the Company in the future, should submit a new employment application or resume.
TAS Energy Inc. guarantees equal employment opportunities to all qualified applicants. All qualified applicants will receive consideration for employment, without regard to age, race, color, religion, sex, sexual orientation, gender identity, or national origin.

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