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Upstream Process Development Jobs in Houston, TX

Clean Harbors

Water Process Engineer

Deer Park, TX · On-site

$95K - $130K/yr

  • Medical

  • Retirement

  • PTO

Opportunities for growth and development for all the stages of your career * 5+ years' experience ... upstream, downstream, and utility sectors. HPC Industrial offers an exceptional three-pronged ...

CleanHarbors

Water Process Engineer

Deer Park, TX · On-site

$95K - $130K/yr

  • Medical

  • Retirement

  • PTO

Opportunities for growth and development for all the stages of your career * 5+ years' experience ... upstream, downstream, and utility sectors. HPC Industrial offers an exceptional three-pronged ...

Stantec

Junior Process Engineer, Houston

Houston, TX · On-site

Supports project team in development of design documentation, plans and reports for relevant ... Oil & Gas Upstream involving production surface facilities & treatment. * Excellent communication ...

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Upstream Process Development information

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$35

How much do upstream process development jobs pay per hour?

As of Aug 14, 2026, the average hourly pay for upstream process development in Houston, TX is $25.32, according to ZipRecruiter salary data. Most workers in this role earn between $22.50 and $26.63 per hour, depending on experience, location, and employer.

What are the key skills and qualifications needed to thrive in upstream process development?

Success in Upstream Process Development requires a strong background in biology, biochemistry, or chemical engineering, often with an advanced degree and experience in cell culture or fermentation techniques. Familiarity with bioreactors, process control systems, and analytical instrumentation, as well as knowledge of cGMP regulations, is essential. Critical thinking, problem-solving, and effective communication are important soft skills for optimizing processes and collaborating across multidisciplinary teams. These competencies ensure efficient development of scalable production processes, maintaining product quality and regulatory compliance.

What is the difference between Upstream Process Development vs Downstream Process Development?

AspectUpstream Process DevelopmentDownstream Process Development
FocusDevelopment of cell culture, fermentation, and bioreactor processesPurification, filtration, and formulation of bioproducts
Skills & CredentialsBioprocess engineering, molecular biology, biochemistryBioprocessing, chromatography, analytical chemistry
Work EnvironmentLaboratories, bioreactors, pilot plantsPurification facilities, labs, quality control
Industry UsageBiotech, pharmaceutical manufacturingBiotech, pharmaceutical manufacturing

Upstream Process Development focuses on creating and optimizing cell culture and fermentation processes to produce bioproducts. In contrast, Downstream Process Development involves purifying and finishing these products. Both roles are essential in biopharmaceutical manufacturing and require similar scientific backgrounds, but they specialize in different stages of bioprocessing.

What are some common challenges faced in upstream process development and how do teams typically address them?

One of the main challenges in upstream process development is optimizing cell culture conditions to consistently achieve high yields and product quality. Teams often encounter variability in biological systems and must troubleshoot issues such as contamination, scale-up inconsistencies, or nutrient limitations. Collaboration with analytical, downstream, and quality teams is essential to identify root causes and implement solutions. Regular data review meetings, cross-functional problem-solving, and continuous process improvement are standard practices to ensure robust upstream processes.

What are popular job titles related to Upstream Process Development jobs in Houston, TX?

For Upstream Process Development jobs in Houston, TX, the most frequently searched job titles are:

What job categories do people searching Upstream Process Development jobs in Houston, TX look for?

The top searched job categories for Upstream Process Development jobs in Houston, TX are:

What cities near Houston, TX are hiring for Upstream Process Development jobs?

Cities near Houston, TX with the most Upstream Process Development job openings:

Upstream Process Development jobs near you
Infographic showing various Upstream Process Development job openings in Houston, TX as of August 2026, with employment types broken down into 1% As Needed, 86% Full Time, 11% Part Time, and 2% Contract. Highlights an 91% Physical, 3% Hybrid, and 6% Remote job distribution, with an average salary of $52,667 per year, or $25.3 per hour.

IT - Technology Lead | Energy Oil & Gas - Upstream | Production Operations

Spruce Infotech

Spring, TX • On-site

Full-time

Re-posted 26 days ago

Job description

Job Title* Technology Lead | Energy Oil & Gas - Upstream | Production Operations
Work Location : Spring, Texas77389
Vendor Rate* XXX/hr
Contract duration (in months)* 6
Job Details:
Must Have Skills (Top 3 technical skills only) * 1. Oil and Gas 2. Data Governance 3. Supply chain
Nice to have skills (Top 2 only)
1. SQL
2. Profiling
Detailed Job Description:
Key Responsibilities Align governance strategy with Supply Chain business goals, priorities, and
value outcomes. Lead the rollout, execution, and ongoing enhancement of the Data Governance
Program across Supply Chain data domainsChair and facilitate the Supply Chain Data Governance
Council, including agenda development, meeting facilitation, and documentation of decisions and
actionsOversee data steward activities to ensure consistent application of enterprise data governance
standards, policies
Minimum years of experience*: 8-10 years
Certifications Needed: No
Top 3 responsibilities you would expect the Subcon to shoulder and execute*:
1. Governance
2. Domain discussions
3. Stakeholder management
Interview Process (Is face to face required?)
No

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