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Upstream Process Development Jobs in Pennsylvania

Upstream Rehabilitation

Physical Therapist

Silver Spring, PA · On-site

$1.7K - $2.2K/wk

Continue learning and growing through Upstream's education and development programs Qualifications ... Specific details will be provided during the hiring process. Follow @Lifeatupstream on Instagram ...

Upstream Rehabilitation

Physical Therapist

Lancaster, PA · On-site

$1.6K - $2.0K/wk

Continue learning and growing through Upstream's education and development programs Qualifications ... Specific details will be provided during the hiring process. Follow @Lifeatupstream on Instagram ...

Upstream Rehabilitation

Physical Therapist

Bellefonte, PA · On-site

$1.5K - $2.0K/wk

Continue learning and growing through Upstream's education and development programs Qualifications ... Specific details will be provided during the hiring process. Follow @Lifeatupstream on Instagram ...

Upstream Rehabilitation

Physical Therapist

Enola, PA · On-site

$1.5K - $1.9K/wk

Continue learning and growing through Upstream's education and development programs Qualifications ... Specific details will be provided during the hiring process. Upstream Rehabilitation is an Equal ...

Upstream Rehabilitation

Physical Therapist

Clearfield, PA · On-site

$1.4K - $1.8K/wk

Continue learning and growing through Upstream's education and development programs Qualifications ... Specific details will be provided during the hiring process. Upstream Rehabilitation is an Equal ...

Upstream Rehabilitation

Physical Therapist

Ephrata, PA · On-site

$1.6K - $2.1K/wk

Continue learning and growing through Upstream's education and development programs Qualifications ... Specific details will be provided during the hiring process. Upstream Rehabilitation is an Equal ...

Upstream Rehabilitation

Physical Therapist

Linglestown, PA · On-site

$1.6K - $2.1K/wk

Continue learning and growing through Upstream's education and development programs Qualifications ... Specific details will be provided during the hiring process. Upstream Rehabilitation is an Equal ...

Upstream Rehabilitation

Physical Therapist

Clearfield, PA · On-site

$1.4K - $1.8K/wk

Continue learning and growing through Upstream's education and development programs Qualifications ... Specific details will be provided during the hiring process. Follow @Lifeatupstream on Instagram ...

Upstream Rehabilitation

Physical Therapist

Shippensburg, PA · On-site

$1.6K - $2.0K/wk

Continue learning and growing through Upstream's education and development programs Qualifications ... Specific details will be provided during the hiring process. Follow @Lifeatupstream on Instagram ...

Upstream Rehabilitation

Physical Therapist

Carlisle, PA · On-site

$1.6K - $2.0K/wk

Continue learning and growing through Upstream's education and development programs Qualifications ... Specific details will be provided during the hiring process. Follow @Lifeatupstream on Instagram ...

Upstream Rehabilitation

Physical Therapist

Middletown, PA · On-site

$1.6K - $2.0K/wk

Continue learning and growing through Upstream's education and development programs Qualifications ... Specific details will be provided during the hiring process. Follow @Lifeatupstream on Instagram ...

Upstream Rehabilitation

Physical Therapist

Fredericksburg, PA · On-site

$1.5K - $1.9K/wk

Continue learning and growing through Upstream's education and development programs Qualifications ... Specific details will be provided during the hiring process. Upstream Rehabilitation is an Equal ...

Upstream Rehabilitation

Physical Therapist

Petersburg, PA · On-site

$1.4K - $1.8K/wk

Continue learning and growing through Upstream's education and development programs Qualifications ... Specific details will be provided during the hiring process. Follow @Lifeatupstream on Instagram ...

Upstream Rehabilitation

Physical Therapist

Du Bois, PA · On-site

$1.4K - $1.8K/wk

Continue learning and growing through Upstream's education and development programs Qualifications ... Specific details will be provided during the hiring process. Follow @Lifeatupstream on Instagram ...

Upstream Rehabilitation

Physical Therapist Assistant

York, PA · On-site

$27.50 - $36.50/hr

... Upstream - with annual allowance! * Pathways for professional development and long-term career ... Specific details will be provided during the hiring process. Upstream Rehabilitation is an Equal ...

Upstream Rehabilitation

Physical Therapist

Duncansville, PA · On-site

$1.4K - $1.8K/wk

Continue learning and growing through Upstream's education and development programs Qualifications ... Specific details will be provided during the hiring process. Upstream Rehabilitation is an Equal ...

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All JobsUpstream Process Development JobsUpstream Process Development Jobs in Pennsylvania

Upstream Process Development information

What are the key skills and qualifications needed to thrive in upstream process development?

Success in Upstream Process Development requires a strong background in biology, biochemistry, or chemical engineering, often with an advanced degree and experience in cell culture or fermentation techniques. Familiarity with bioreactors, process control systems, and analytical instrumentation, as well as knowledge of cGMP regulations, is essential. Critical thinking, problem-solving, and effective communication are important soft skills for optimizing processes and collaborating across multidisciplinary teams. These competencies ensure efficient development of scalable production processes, maintaining product quality and regulatory compliance.

What is the difference between Upstream Process Development vs Downstream Process Development?

AspectUpstream Process DevelopmentDownstream Process Development
FocusDevelopment of cell culture, fermentation, and bioreactor processesPurification, filtration, and formulation of bioproducts
Skills & CredentialsBioprocess engineering, molecular biology, biochemistryBioprocessing, chromatography, analytical chemistry
Work EnvironmentLaboratories, bioreactors, pilot plantsPurification facilities, labs, quality control
Industry UsageBiotech, pharmaceutical manufacturingBiotech, pharmaceutical manufacturing

Upstream Process Development focuses on creating and optimizing cell culture and fermentation processes to produce bioproducts. In contrast, Downstream Process Development involves purifying and finishing these products. Both roles are essential in biopharmaceutical manufacturing and require similar scientific backgrounds, but they specialize in different stages of bioprocessing.

What are some common challenges faced in upstream process development and how do teams typically address them?

One of the main challenges in upstream process development is optimizing cell culture conditions to consistently achieve high yields and product quality. Teams often encounter variability in biological systems and must troubleshoot issues such as contamination, scale-up inconsistencies, or nutrient limitations. Collaboration with analytical, downstream, and quality teams is essential to identify root causes and implement solutions. Regular data review meetings, cross-functional problem-solving, and continuous process improvement are standard practices to ensure robust upstream processes.

What are popular job titles related to Upstream Process Development jobs in Pennsylvania?

For Upstream Process Development jobs in Pennsylvania, the most frequently searched job titles are:

What job categories do people searching Upstream Process Development jobs in Pennsylvania look for?

The top searched job categories for Upstream Process Development jobs in Pennsylvania are:

What cities in Pennsylvania are hiring for Upstream Process Development jobs?

Cities in Pennsylvania with the most Upstream Process Development job openings:

Upstream Process Development jobs near you
Infographic showing various Upstream Process Development job openings in Pennsylvania as of August 2026, with employment types broken down into 85% Full Time, and 15% Contract. Highlights an 96% In-person, and 4% Remote job distribution.

Physical Therapist

Upstream Rehabilitation

Silver Spring, PA • On-site

$1.7K - $2.2K/wk

Full-time, Part-time, Per diem

Medical, Dental, Vision, Retirement, PTO

Re-posted 29 days ago

Upstream Rehabilitation rating

6.3

Company rating: 6.3 out of 10

Based on 69 frontline employees who took The Breakroom Quiz

671st of 887 rated healthcare providers

Job description

Physical Therapist - Outpatient Ortho
Silver Spring PA
Build Your Outpatient Physical Therapy Career with us!
At Drayer Physical Therapy Institute, part of the Upstream Rehabilitation network, you can focus on patient care while advancing your career in outpatient orthopedic physical therapy.
We're hiring full-time, part-time, and PRN Physical Therapists - including new grads - who want competitive pay, strong mentorship, and a clear path to professional growth that flexes with every stage of your career.
Why Clinicians Choose Drayer Physical Therapy
  • Competitive Physical Therapist salary $78,000 to $95,000
  • Achievable monthly clinical bonus program, over 90% of clinicians qualify
  • Student loan repayment assistance - directly to the principle of your loan!
  • 100% employer paid medical health insurance premium option available
  • Dental and Vision insurance
  • 401(k) with company match
  • Generous PTO and paid holidays
  • Structured onboarding for new-grad Physical Therapists and ongoing mentorship
  • In-house Residency/Fellowship programs and robust CEU opportunities - with annual allowance!
  • Path to clinic ownership / partnership for long-term growth
  • Modern clinical technology that reduces documentation time so you can focus on patients
  • Supportive team and leadership invested in your success

What You'll Do as a Physical Therapist
  • Develop individualized, evidence-based care plans for your patients
  • Deliver high-quality, outcomes-driven therapy
  • Collaborate with peers in a fun, values-driven team environment
  • Build lasting connections with patients and local providers
  • Continue learning and growing through Upstream's education and development programs

Qualifications
  • Graduate of an accredited Physical Therapy program (DPT or equivalent)
  • Active Pennsylvania Physical Therapist license (or eligible)

A Better Place to Build Your PT Career
When you join Upstream Rehabilitation, you get the strength of a national network with the feel of a local clinic.
Our central support teams handle the administrative work, so you can focus on what matters most - the patient in front of you. With a network of over 1,200 clinics coast-to-coast across 26 brand partners, we lead the industry in quality outcomes, leveraging data, technology, and innovation to reduce paperwork and give you more time for care.
You'll be part of a fantastic group of clinicians who shape our culture, create a positive work environment, and know how to have fun along the way. It's easy to see why so many Physical Therapists choose to grow their careers with Upstream.
Estimated pay ranges listed above are based on several factors including but not limited to your pay class, experience, background and geographic location of the clinic
Benefits and eligibility are dependent on employment status and pay class (full-time, part-time, or PRN). Specific details will be provided during the hiring process.
Follow @Lifeatupstream on Instagram, and check out our LinkedIn company page to learn more about what it's like to be part of the #upstreamfamily.
CLICK HERE TO LEARN EVEN MORE ABOUT UPSTREAM
Upstream Rehabilitation is an Equal Opportunity Employer that strives to provide an inclusive work environment where our differences are celebrated for the value they bring to our communities, our patients and our teammates. Upstream Rehabilitation does not discriminate on the basis of race, color, national origin, religion, gender (including pregnancy), sexual orientation, age, disability, veteran status, or other status protected under applicable law.

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