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Upstream Process Development Jobs in Pennsylvania

Merck & Co.

Provide expert consultation on upstream, downstream, analytical, and manufacturing strategies ... process development.Deep expertise spanning the full product lifecycle, from early development ...

Valspec

Process Validation Engineer

Philadelphia, PA

$70 - $80/hr

Process Engineer -- Upstream / Downstream / Clean Utilities (Consultant) -- Contract Engagement ... Join a team where your contributions matter, your development is prioritized, and your success is ...

New

Upstream Rehabilitation

Physical Therapist

Dillsburg, PA · On-site

$1.5K - $1.9K/wk

Continue learning and growing through Upstream's education and development programs Qualifications ... Specific details will be provided during the hiring process. Follow @Lifeatupstream on Instagram ...

Upstream Rehabilitation

Physical Therapist

Red Lion, PA · On-site

$1.6K - $2.0K/wk

Continue learning and growing through Upstream's education and development programs Qualifications ... Specific details will be provided during the hiring process. Follow @Lifeatupstream on Instagram ...

Upstream Rehabilitation

Physical Therapist

Lancaster, PA · On-site

$1.6K - $2.0K/wk

Continue learning and growing through Upstream's education and development programs Qualifications ... Specific details will be provided during the hiring process. Follow @Lifeatupstream on Instagram ...

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All JobsUpstream Process Development JobsUpstream Process Development Jobs in Pennsylvania

Upstream Process Development information

What jobs pay 500,000 a year in the US?

In the field of Upstream Process Development, senior roles such as Director or Vice President can reach or exceed $500,000 annually, especially with bonuses and stock options. These positions typically require extensive experience, advanced degrees, and leadership skills in biopharmaceutical or biotech industries. High compensation is often associated with managerial responsibilities, strategic decision-making, and overseeing large teams or projects.

What are the key skills and qualifications needed to thrive in Upstream Process Development, and why are they important?

Success in Upstream Process Development requires a strong background in biology, biochemistry, or chemical engineering, often with an advanced degree and experience in cell culture or fermentation techniques. Familiarity with bioreactors, process control systems, and analytical instrumentation, as well as knowledge of cGMP regulations, is essential. Critical thinking, problem-solving, and effective communication are important soft skills for optimizing processes and collaborating across multidisciplinary teams. These competencies ensure efficient development of scalable production processes, maintaining product quality and regulatory compliance.

What are common upstream jobs?

Common upstream process development jobs include roles such as upstream process scientist, bioprocess engineer, and fermentation scientist. These positions focus on developing and optimizing the early stages of biopharmaceutical production, often requiring knowledge of cell culture, bioreactor operation, and process scale-up. Skills in laboratory techniques, process analytical technology, and regulatory compliance are also important in these roles.

What biology jobs pay over $100k?

In upstream process development, senior roles such as Process Development Managers, Principal Scientists, and Regulatory Affairs Directors often have salaries exceeding $100,000. These positions typically require advanced degrees, extensive industry experience, and expertise in bioprocessing, quality control, or regulatory compliance.

What is the difference between Upstream Process Development vs Downstream Process Development?

AspectUpstream Process DevelopmentDownstream Process Development
FocusDevelopment of cell culture, fermentation, and bioreactor processesPurification, filtration, and formulation of bioproducts
Skills & CredentialsBioprocess engineering, molecular biology, biochemistryBioprocessing, chromatography, analytical chemistry
Work EnvironmentLaboratories, bioreactors, pilot plantsPurification facilities, labs, quality control
Industry UsageBiotech, pharmaceutical manufacturingBiotech, pharmaceutical manufacturing

Upstream Process Development focuses on creating and optimizing cell culture and fermentation processes to produce bioproducts. In contrast, Downstream Process Development involves purifying and finishing these products. Both roles are essential in biopharmaceutical manufacturing and require similar scientific backgrounds, but they specialize in different stages of bioprocessing.

What is upstream process development?

Upstream process development involves designing and optimizing the initial stages of biopharmaceutical production, such as cell culture and fermentation, to produce target biological products. It requires knowledge of bioprocessing, cell biology, and often involves working with bioreactors and process control systems to ensure consistent, high-quality output.

What are some common challenges faced in upstream process development and how do teams typically address them?

One of the main challenges in upstream process development is optimizing cell culture conditions to consistently achieve high yields and product quality. Teams often encounter variability in biological systems and must troubleshoot issues such as contamination, scale-up inconsistencies, or nutrient limitations. Collaboration with analytical, downstream, and quality teams is essential to identify root causes and implement solutions. Regular data review meetings, cross-functional problem-solving, and continuous process improvement are standard practices to ensure robust upstream processes.
What are popular job titles related to Upstream Process Development jobs in Pennsylvania? For Upstream Process Development jobs in Pennsylvania, the most frequently searched job titles are:
What job categories do people searching Upstream Process Development jobs in Pennsylvania look for? The top searched job categories for Upstream Process Development jobs in Pennsylvania are:
What cities in Pennsylvania are hiring for Upstream Process Development jobs? Cities in Pennsylvania with the most Upstream Process Development job openings:
Upstream Process Development jobs near you
Infographic showing various Upstream Process Development job openings in Pennsylvania as of July 2026, with employment types broken down into 1% As Needed, 80% Full Time, 17% Part Time, and 2% Contract. Highlights an 92% Physical, 2% Hybrid, and 6% Remote job distribution.
Process Scientist (Philadelphia, PA)

Process Scientist (Philadelphia, PA)

Cedent

Philadelphia, PA • On-site

Full-time

Posted 6 days ago

Job description

Title : Process Scientist
Report: CTO
Location: Philadelphia, PA
Position Type : Full Time, Exempt
Travel: Occasional (0-10%)
Position Summary
This position is part of the Technology team responsible for Client technology development, process development, and assisting in transferring developed process to GMP manufacturing. A Scientist is a mid-level individual with understanding of cell/molecular biology and previous experience in either upstream or downstream biopharmaceutical processing that utilizes bioreactors. A Scientist is responsible for hands-on execution of experiments and technology transfer, as well as authoring experimental protocols, SOPs, and batch documents. A Scientist is expected to independently complete objectives given by supervisor, serve as a role model to junior scientists, collaborate cross-functionally, and provide support with any other technology, process development, and manufacturing needs.
Key Responsibilities
  • Independently contribute to technology/process development for specific bioprocessing steps, ensuring delivery in alignment with Client strategy
  • Support Senior/Principal Scientist with experimental design, execution and data analysis, effectively communicating technical results to management
  • Author protocols, SOPs, and batch documents to ensure the successful transfer of technology/process development to GMP manufacturing
  • Perform as a Subject Matter Expert on a cross-functional team to implement novel process.
  • Work closely with suppliers and other partners to drive forward technology development initiatives
  • Serve as a good financial steward to the Technology team at Client and help to implement budgetary adherence and financial governance
  • Coach and train junior scientists/employees on activities and documentation related to technology development, process development.
  • Other related duties as assigned.
Education and Experience
  • Minimum Bachelor's degree in Biological Engineering, Biotechnology, Biology, Biochemistry, or other related field. Master's preferred.
  • 2-3 years of industry or academic experience in combination with Bachelor's or Master's degree.
Knowledge, Skills and Abilities
  • Experience with methodologies used for upstream or downstream viral vector production in either industry or academia
  • Experience in experimental design, execution, and data analysis
  • Excellent communication, collaboration, and technical writing skills
  • Innovative and creative mindset, with problem solving capabilities
  • Proficient in Microsoft Office products.
Physical Requirements
  • Ability to lift and carry up to 30lbs
  • Ability to sit and stand for extended periods
  • Excellent manual dexterity and ability to perform repetitive movements with fingers/hands
Other Physical Requirements: PPE and gown training will be required as this individual will be required to enter into Laboratory and Cleanroom areas.
Work Environment: Work is performed primarily onsite in Philadelphia. 50% or more of the time, this role is in the laboratory.
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About Cedent

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CEDENT strives to attract and retain the best people and provide an environment where they can all develop professionally and build a rewarding career. As a result, we create an inclusive environment that is rich in diversity, acknowledges each individual's uniqueness and promotes respect, personal achievement and stewardship. Our clients are global and so is CEDENT. We build and maintain a global workforce that includes people from different backgrounds, with a vast range of skills and experience all united by a common culture and commitment to help our clients achieve high performance. Cultivating a diverse workforce and inclusive work environment makes business sense. Our peoples varied skills are the talent engine that powers CEDENT, enabling it in turn to deliver the innovative solutions that help our clients outperform competitors.

Industry

It services

Company size

11 - 50 Employees

Headquarters location

Plano, TX, US

Year founded

2008

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