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Upstream Manufacturing Associate Jobs in Virginia

Upstream Manufacturing Associate information

See Virginia salary details

$12

$20

$33

How much do upstream manufacturing associate jobs pay per hour?

As of Aug 22, 2026, the average hourly pay for upstream manufacturing associate in Virginia is $20.66, according to ZipRecruiter salary data. Most workers in this role earn between $16.20 and $23.12 per hour, depending on experience, location, and employer.

What is an upstream manufacturing associate?

Upstream Manufacturing Associates are professionals who work in the early stages of biopharmaceutical production, primarily focusing on cell culture and fermentation processes. They are responsible for preparing and maintaining bioreactors, monitoring cell growth, and ensuring optimal conditions for producing biological products such as proteins or vaccines. Their role is crucial in setting the foundation for downstream purification and final product manufacturing. Upstream Manufacturing Associates often work in cleanroom environments and follow strict safety and quality protocols.

What skills and qualifications are needed to be an upstream manufacturing associate?

To thrive as an Upstream Manufacturing Associate, you need a solid background in biology or biochemistry, familiarity with Good Manufacturing Practices (GMP), and typically a bachelor's degree in a scientific field. Experience with bioreactor operation, aseptic techniques, and process control systems such as DeltaV is often required. Strong attention to detail, teamwork, and effective communication are crucial soft skills in this role. These competencies ensure the consistent production of high-quality biological products and compliance with industry regulations in a fast-paced environment.

What challenges do upstream manufacturing associates face and how can they be managed?

Upstream Manufacturing Associates often encounter challenges such as maintaining sterility in bioprocessing environments, troubleshooting equipment malfunctions, and adapting to rapidly changing production schedules. Successfully managing these challenges requires strict adherence to standard operating procedures (SOPs), strong attention to detail, and effective communication with cross-functional teams like quality assurance and process engineering. Proactively seeking feedback, participating in ongoing training, and staying organized can help associates stay ahead of potential issues and contribute positively to team goals.

What is the difference between Upstream Manufacturing Associate vs Downstream Manufacturing Associate?

AspectUpstream Manufacturing AssociateDownstream Manufacturing Associate
Primary ResponsibilitiesBioreactor operation, cell culture, media preparationPurification, filtration, packaging of products
Work EnvironmentCleanroom, laboratory, manufacturing floorCleanroom, laboratory, manufacturing floor
Required SkillsBioprocessing, sterile techniques, equipment handlingFiltration, chromatography, aseptic processing
CertificationsGMP training, sterile technique certificationGMP training, sterile technique certification

Both roles are essential in biopharmaceutical manufacturing, with upstream associates focusing on the early stages of production like cell culture, and downstream associates handling product purification and finishing. They often work in similar environments and require comparable certifications, but their specific tasks differ within the manufacturing process.

What cities in Virginia are hiring for Upstream Manufacturing Associate jobs?

Cities in Virginia with the most Upstream Manufacturing Associate job openings:

Research Associate in Chemical Engineering

University of Virginia

Charlottesville, VA • On-site

$57K - $60K/yr

Full-time

Posted 24 days ago


University Of Virginia rating

7.9

Company rating: 7.9 out of 10

Based on 35 frontline employees who took The Breakroom Quiz

209th of 621 rated colleges and universities


Job description

University of Virginia | Department of Chemical Engineering | Vecchiarello Lab
Job Description: We are seeking to fill a postdoctoral associate position for a highly motivated and driven candidate in the Vecchiarello Lab as a part of an industrial collaboration project focused on protein chromatography. This is an excellent opportunity for an interested candidate to learn and practice a variety of industrially-transferrable skills including operation of chromatographic equipment (FPLC/Akta Pure, automated liquid handling systems, and HPLC/UHPLC). Further, the selected candidate will have the opportunity to grow a strong industrial and academic network by attending and presenting at conferences, and by providing regularly updates to our industrial sponsor.
Primary Responsibilities: The chosen candidate will work on an industrial collaboration with a large pharmaceutical manufacturing company, focused on improving fundamental understanding of transport and adsorptive phenomena in protein chromatography. The candidate will implement a combination of high-throughput experimentation and modeling to achieve project milestones. Additionally, the candidate will provide regular project progress updates to the company sponsor. Within this role, the selected candidate will learn to measure protein adsorption isotherms, protein transport parameters in chromatographic resin, design preparative and analytical chromatographic purification processes for new protein biologics, and predict chromatographic performance by leveraging existing and new mechanistic column models in Matlab®, Python®, or GoSilico® software package suites.
Qualifications:
Minimum Education Requirements:
  • A Ph.D. in Chemical Engineering, Engineering, Chemistry, Physics, or a closely-related field by the start date.

Preferred Experience and Skills:
  • Technical background in large biomolecules upstream (e.g. microbial fermentation, mammalian cell & virus culture) and/or downstream (e.g. harvest, filtration, chromatography, conjugation) unit operations.
  • Experience with scripting/programing, and/or developing and implementing microscale models process unit operations.
  • Demonstrated scientific ability through publications and presentation in scientific conferences.
  • Ability to effectively and clearly communicate researching findings, results, and analysis
  • Ability to work in a team environment.
  • Motivated to learn new skills, willingness to take on new challenges, and scientific curiosity.

APPLICATION PROCEDURE: Apply at https://uva.wd1.myworkdayjobs.com/UVAJobs and search for R0085874. Attach a cover letter indicating research interests, a detailed curriculum vitae, and contact information for three references. Please note that multiple documents can be uploaded in the CV box. Make sure to upload all the documents to complete your application.
APPLICATION DEADLINE: Review of applications will begin on August 22, 2026 and the posting will remain open until filled. The University will perform background checks on all new hires prior to employment.
Estimated Salary range is $57,000 - $60,000, commensurate with experience.
This is a one-year appointment that may be renewed for up to two additional one-year terms, contingent upon available funding and satisfactory performance.
For questions regarding this position, please contact Professor Nick Vecchiarello at qzv7pp@virginia.edu.
For questions about the application process, please contact Rich Haverstrom, Academic Recruiter, at rkh6j@virginia.edu .
For more information on the benefits available to postdoctoral associates at UVA, visit postdoc.virginia.edu and hr.virginia.edu/benefits.
The University of Virginia is an equal opportunity employer. All interested persons are encouraged to apply, including veterans and individuals with disabilities. Learn more about UVA's commitment to non-discrimination and equal opportunity employment .

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About University of Virginia

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The University of Virginia is distinctive among institutions of higher education. Founded by Thomas Jefferson in 1819, the University sustains the ideal of developing, through education, leaders who are well-prepared to shape the future of the nation.

Industry

Colleges, universities, and professional schools

Company size

10,000+ Employees

Headquarters location

Charlottesville, VA, US

Year founded

1819