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Staff Scientist - Hematologic Malignancies

Staff Scientist - Hematologic Malignancies

City of Hope

Duarte, CA

Full-time

Posted 26 days ago

City Of Hope rating

8.4

Company rating: 8.4 out of 10

Based on 87 frontline employees who took The Breakroom Quiz

18th of 870 rated healthcare providers

Job description

Join the forefront of groundbreaking research at City of Hope, where we're changing lives and making a real difference in the fight against cancer, diabetes, and other life-threatening illnesses. Our dedicated and compassionate faculty and staff are driven by a common mission: Contribute to innovative approaches in predicting, preventing, and curing diseases, shaping the future of medicine through cutting-edge research. 

A Staff Scientist position is available in the research laboratory of the Division of Hematopathology, Department of Pathology at City of Hope. A Staff Scientist focuses on translational research in hematologic malignancies using genetically engineered mouse models, patient-derived samples, and molecular profiling techniques. The Staff Scientist will lead and support experiments involving in vivo modeling, flow cytometry, genomic and transcriptomic analysis, and tissue-based assays to investigate disease mechanisms, identify biomarkers, and refine diagnostics. Responsibilities include experimental design, data interpretation, manuscript preparation, and supervision of lab operations, with collaboration across clinical and research teams to advance studies with direct diagnostic and therapeutic impact.

For more information about Dr. You’s lab, please visit here.

As a successful candidate, you will:

  • Design and execute experiments involving genetically engineered mouse models, patient-derived samples, and molecular assays, including DNA/RNA sequencing, immunohistochemistry, and flow cytometry.

  • Develop and optimize laboratory protocols for studying disease mechanisms, biomarker discovery, and diagnostic refinement in hematologic malignancies.

  • Analyze and interpret experimental data using appropriate computational tools and collaborate with bioinformatics staff when necessary.

  • Troubleshoot laboratory equipment (e.g., flow cytometers, sequencers) and coordinate routine maintenance and quality control.

  • Work collaboratively with team members to design experiments, interpret findings, and contribute to manuscript and grant preparation.

  • Communicate experimental results clearly to faculty, trainees, and clinical collaborators; contribute to team meetings and project planning.

  • Provide mentorship and training to junior lab members on experimental design, execution, and data analysis.

  • Maintain meticulous and organized records of all experiments and ensure proper documentation for data reproducibility.

  • Adhere to institutional and laboratory safety regulations and compliance standards for working with human samples and animal models.

Your qualifications should include:

  • PhD, MD, or MD/PhD degree in a relevant biomedical field (or commensurate experience) with a minimum of 3 years of hands-on experience in a clinical or research laboratory focused on hematologic malignancies, molecular pathology, or flow cytometry.

  • Demonstrated expertise in data analysis and immunophenotyping; experience with cell sorting is highly desirable.

  • Proven ability to design and execute experiments using mouse models, primary human samples, and genomic profiling tools (e.g., NGS, RNA-seq).

  • Demonstrated leadership in mentoring junior staff and managing laboratory operations.

City of Hope employees pay is based on the following criteria: work experience, qualifications, and work location.

City of Hope is an equal opportunity employer.

To learn more about our Comprehensive Benefits, please CLICK HERE.

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About City of Hope

Sourced by ZipRecruiter

City of Hope is an independent biomedical research and treatment organization for cancer, diabetes and other life-threatening diseases. Founded in 1913, City of Hope is a leader in bone marrow transplantation and immunotherapy such as CAR T cell therapy. City of Hopes translational research and personalized treatment protocols advance care throughout the world. Human synthetic insulin, monoclonal antibodies and numerous breakthrough cancer drugs are based on technology developed at the institution. AccessHope, a subsidiary launched in 2019 serves employers and their health care partners by providing access to City of Hopes specialized cancer expertise. City of Hope is ranked among the nations Best Hospitals in cancer by U.S. News & World Report and received Magnet Recognition from the American Nurses Credentialing Center. Its main campus is located near Los Angeles, with additional locations throughout Southern California and in Arizona.

Industry

Hospitals

Company size

1,001 - 5,000 Employees

Headquarters location

Duarte, CA, US

Year founded

1913

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