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Trainee Biomarker Jobs (NOW HIRING)

Saint Louis University

Post Doctoral Fellow

Saint Louis, MO

$47K - $64K/yr

The position is ideal for a candidate interested in mechanistic discovery, biomarker development ... Mentor graduate or undergraduate trainees in computational methods (optional, depending on interest ...

Saint Louis University

Post Doctoral Fellow

Saint Louis, MO · On-site

$47K - $64K/yr

The position is ideal for a candidate interested in mechanistic discovery, biomarker development ... Mentor graduate or undergraduate trainees in computational methods (optional, depending on interest ...

Washington University of St. Louis

The development of biomarker tests and disease-modifying treatments for early symptomatic Alzheimer ... Collegial conduct towards co-trainees, staff members and members of the research group. * Adherence ...

NorthEastern

Postdoctoral Research Fellow

Portland, ME · On-site

$60K - $85K/yr

Under this program, the postdoctoral trainee will be co-mentored by NU and JAX researchers working ... The team is performing complementary human and mouse studies to evaluate plasma biomarkers in ...

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Postdoctoral Fellow - Bioinformatics, Cancer Biology and Predictive Biomarkers (Hybrid)

Postdoctoral Fellow - Bioinformatics, Cancer Biology and Predictive Biomarkers (Hybrid)

City of Hope

Duarte, CA • On-site

$51K - $69K/yr

Other

Posted 3 days ago

City Of Hope rating

8.4

Company rating: 8.4 out of 10

Based on 87 frontline employees who took The Breakroom Quiz

18th of 871 rated healthcare providers

Job description

Join the forefront of groundbreaking research at City of Hope where we're changing lives and making a real difference in the fight against cancer, diabetes, and other life-threatening illnesses. Our dedicated and compassionate faculty and staff are driven by a common mission: Contribute to innovative approaches in predicting, preventing, and curing diseases, shaping the future of medicine through cutting-edge research.

The Bild Laboratory at City of Hope uses systems biology to understand how tumors evolve under therapy, uncover resistance mechanisms, and identify actionable vulnerabilities. We integrate longitudinal patient cohorts with single-cell and bulk multi-omics, liquid biopsy, and patient-derived models, partnering closely with clinicians at an NCI-designated Comprehensive Cancer Center.

We seek a Postdoctoral Research Fellow (bioinformatics) to lead analysis of large, longitudinal multi-omic datasets from cancer patients on therapy. You will build scalable pipelines across data types and translate results into biomarker discovery, downstream modeling, and clinical interpretation.

This role fits a scientist who enjoys hands-on cohort processing and harmonization and wants analyses to directly inform how tumors evade treatment. You will collaborate with computational scientists developing predictive models, contributing genomic analysis, workflow engineering, biological interpretation, and (when appropriate) machine-learning methods.

Learn more about Dr. Bild's lab here.

As a successful candidate you will:

  • Build reproducible pipelines for serial tumor and liquid-biopsy data across large cohorts.

  • Analyze somatic variation (SNV/indel, CNV/SV), methylation, and deconvolution in longitudinal ctDNA and tissue.

  • Integrate bulk and single-cell RNA-seq with genomic/epigenomic data to define tumor states, microenvironment, and resistance programs.

  • Co-develop and validate drug-response biomarkers with computational, experimental, and clinical teams.

  • Publish and present results, mentor trainees, and grow an independent research direction.

Your qualifications should include:

  • PhD (or equivalent) in bioinformatics, computational biology, genomics, systems biology, biomedical engineering, statistics, computer science, or a related quantitative field (completed within five years or expected within six months).

Demonstrated expertise across most of the following areas:

Cancer biology and genomics domain knowledge

  • Working understanding of cancer biology and signaling, and how DNA mutation/methylation affects RNA and protein.

  • Familiarity with standard cancer-genomics analyses (somatic calling, CNV/SV, mutational signatures, purity/ploidy, clonal structure).

  • Liquid biopsy experience (ctDNA/cfDNA methylation/CTCs) and knowledge of biomarker validation frameworks preferred.

Bioinformatics and computational skills

  • Proven ability to process large-scale sequencing data end-to-end and build reproducible workflows on HPC and/or cloud (AWS/GCP/Azure).

  • Proficiency with R/Bioconductor and Python, git, containers (Docker/Singularity), and core genomics formats (BAM/CRAM, VCF, MAF).

  • Familiarity with common aligners/callers and single-cell toolchains (e.g., BWA/STAR, Mutect2, Seurat/Scanpy) is expected.

Statistics and data analysis

  • Strong applied statistics for genomic data (multiple testing, multivariate methods, dimensionality reduction, differential expression/methylation, survival analysis). 

  • Experience with longitudinal designs, batch correction, and multimodal integration is valued; ML for classification/response prediction is a plus.

Scholarly record and collaboration

  • First-author publications (or preprints) and clear communication skills to work with wet-lab biologists, clinicians, and computational scientists.

 

City of Hope employees pay is based on the following criteria: work experience, qualifications, and work location.

 

City of Hope is an equal opportunity employer.

 

To learn more about our Comprehensive Benefits, please CLICK HERE.

 

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About City of Hope

Sourced by ZipRecruiter

City of Hope is an independent biomedical research and treatment organization for cancer, diabetes and other life-threatening diseases. Founded in 1913, City of Hope is a leader in bone marrow transplantation and immunotherapy such as CAR T cell therapy. City of Hopes translational research and personalized treatment protocols advance care throughout the world. Human synthetic insulin, monoclonal antibodies and numerous breakthrough cancer drugs are based on technology developed at the institution. AccessHope, a subsidiary launched in 2019 serves employers and their health care partners by providing access to City of Hopes specialized cancer expertise. City of Hope is ranked among the nations Best Hospitals in cancer by U.S. News & World Report and received Magnet Recognition from the American Nurses Credentialing Center. Its main campus is located near Los Angeles, with additional locations throughout Southern California and in Arizona.

Industry

Hospitals

Company size

1,001 - 5,000 Employees

Headquarters location

Duarte, CA, US

Year founded

1913

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