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System Integration Engineer Jobs in California (NOW HIRING)

Lead system-level debugging when issues cross subsystem boundaries or no single team can isolate ... Engineering, or related technical field. * 5+ years of experience in hardware/software integration ...

Hardware Engineering is an innovative and collaborative group of electrical, mechanical ... This role follows a hybrid work schedule and reports to Systems Integration Manager. You will:

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System Integration Engineer information

See California salary details

$64.1K

$155K

$165.3K

How much do system integration engineer jobs pay per year?

As of Aug 11, 2026, the average yearly pay for system integration engineer in California is $154,986.00, according to ZipRecruiter salary data. Most workers in this role earn between $164,800.00 and $164,800.00 per year, depending on experience, location, and employer.

What does a system integration engineer do?

A System Integration Engineer is responsible for designing, implementing, and maintaining the seamless integration of various software, hardware, and network systems. They collaborate with cross-functional teams to ensure different components work together effectively, troubleshoot technical issues, and optimize system performance. Their role often includes developing integration solutions, testing system compatibility, and maintaining documentation for future scalability.

What are the key skills and qualifications needed to thrive as a system integration engineer?

To thrive as a System Integration Engineer, you need a strong background in systems engineering, software integration, and troubleshooting, typically supported by a degree in engineering or computer science. Experience with integration platforms, scripting languages, hardware interfaces, and certifications such as INCOSE or related vendor certifications is highly valuable. Excellent problem-solving skills, attention to detail, and the ability to communicate clearly with cross-functional teams are key soft skills in this position. These skills ensure complex systems function cohesively, deliver reliable results, and enable effective collaboration in multidisciplinary projects.

What are some common challenges faced by system integration engineers in their day-to-day work?

System Integration Engineers often encounter the challenge of ensuring compatibility and seamless communication between diverse hardware and software components sourced from different vendors. Troubleshooting integration issues under tight project deadlines can require quick thinking and creative solutions. Additionally, these engineers must coordinate with various teams—from software developers to network specialists—to resolve dependencies and meet project requirements. This role offers valuable exposure to complex, cutting-edge systems and provides excellent opportunities for professional growth in technical leadership and project management.

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What cities in California are hiring for System Integration Engineer jobs? Cities in California with the most System Integration Engineer job openings:
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Infographic showing various System Integration Engineer job openings in California as of August 2026, with employment types broken down into 1% As Needed, 82% Full Time, 13% Part Time, 2% Temporary, and 2% Contract. Highlights an 92% Physical, 2% Hybrid, and 6% Remote job distribution, with an average salary of $154,986 per year, or $74.5 per hour.

Systems Integration Engineer

Ansa Biotechnologies

Emeryville, CA • On-site

$170K - $190K/yr

Full-time

Medical, Dental, Vision

Posted 13 days ago


Job description

Our mission at Ansa Biotechnologies is to revolutionize the way we make DNA. Compared to reading or editing life's code, writing new code from scratch has remained one of the field's most elusive challenges. At Ansa, we are putting nature to work, creating novel enzymatic solutions that will redefine how we build DNA. We believe that the biggest challenges our world faces will be solved using biotechnology and that DNA synthesis is the fuel for that transformation. Our enzyme-based approach (published in Nature Biotechnology) promises to dramatically accelerate innovation in biological research and biotechnology, including therapeutics, diagnostics, biomanufacturing, and synthetic biology. We look forward to our DNA products making an impact.
Job Summary
Ansa is seeking an experienced systems integration engineer with deep expertise in Salesforce, NetSuite, and MuleSoft to join our engineering team. We are building sophisticated integrations that connect our core CRM platform, financial systems, and custom manufacturing execution system to enable seamless data flow across Ansa's manufacturing operations. By joining this team of talented engineers, you will be responsible for designing, building, and maintaining robust integration solutions that automate critical business processes, enhance operational efficiency, and bring joy to our customers. Success means reliable, scalable systems that serve both our commercial and manufacturing operations with minimal downtime and maximum visibility. This is an opportunity to work at an exciting biotech startup, building the systems that power Ansa's growth.
Responsibilities
  • Design and build production-quality integrations between Salesforce, NetSuite, and Ansa's custom manufacturing execution system, emphasizing data integrity and reliability
  • Develop robust Flows and Apex solutions to extend core platform functionality and automate business processes across CRM and financial systems
  • Design and develop new features for Ansa's customer-facing web API
  • Architect and implement MuleSoft integrations that reliably connect disparate systems and handle complex data transformation requirements
  • Own the application of system engineering best practices in Salesforce, including distributed version control, peer code review, automated testing, and CI/CD pipelines
  • Collaborate with cross-functional teams-product, finance, manufacturing, and IT-to understand requirements, validate design approaches, and deliver solutions that meet business needs
  • Diagnose and resolve production integration issues rapidly, perform root cause analysis, and implement preventative measures
  • Share the team's commitment to curiosity, collaboration, and continuous improvement in a fast-moving startup environment

Required Experience
  • 5+ years of professional software development experience, with significant depth in building enterprise integrations or platform extensions, including event-driven or asynchronous architecture patterns
  • Demonstrated mastery of software engineering best practices: distributed version control, peer code review, automated testing (unit and integration tests), infrastructure-as-code, and CI/CD pipelines
  • Strong hands-on experience with Salesforce development, particularly Apex and the Salesforce platform ecosystem
  • Solid experience architecting and implementing integrations with MuleSoft
  • REST API design and implementation
  • Proficiency with Python for integration scripting, data processing, or utility development
  • Hands-on experience building and deploying solutions on a cloud platform such as AWS
  • Excellent problem-solving, communication, and collaboration skills
  • Manufacturing, customer service, or supply chain domain knowledge

What We Offer
  • Competitive salary and equity.
  • Generous benefits package including health, dental, and vision.
  • Ongoing professional development and training opportunities.
  • A collaborative and innovative work environment.
  • The opportunity to be part of a company at the forefront of synthetic biology and innovation.

San Francisco Bay Area Pay Range
$170,000 - $190,000
Ansa Biotechnologies is an Equal Opportunity EmployerAll qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation,
gender identity or expression, national origin, age, disability, veteran status, or any other
characteristic protected by applicable law.
At Ansa, we are building a high-performing team focused on changing how scientists access
DNA. We look for people who are curious, rigorous, accountable, and excited to work on hard
problems. Our hiring decisions are based on merit, qualifications, experience, and the needs of
the business.