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Statistical Programming Jobs in California (NOW HIRING)

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Statistical Programming information

See California salary details

$83.4K

$145.4K

$245.7K

How much do statistical programming jobs pay per year?

As of Jul 15, 2026, the average yearly pay for statistical programming in California is $145,363.00, according to ZipRecruiter salary data. Most workers in this role earn between $123,400.00 and $157,900.00 per year, depending on experience, location, and employer.

What are some common challenges faced by statistical programmers when collaborating with cross-functional teams in clinical research?

Statistical programmers in clinical research often work closely with biostatisticians, data managers, and clinical teams. A common challenge is ensuring clear communication regarding data requirements, analysis specifications, and timelines, as different teams may have varying priorities and technical backgrounds. Navigating frequent changes in study protocols or data standards can also require adaptability and strong project management skills. Building collaborative relationships and maintaining thorough documentation are key to overcoming these challenges and ensuring high-quality, reproducible results.

What is statistical programming?

Statistical programming involves using software tools and programming languages, such as R, SAS, or Python, to manage, analyze, and interpret large sets of data. Professionals in this field write code to perform statistical analyses, create data visualizations, and automate data processing tasks. Statistical programming is widely used in industries like pharmaceuticals, finance, public health, and research to support data-driven decision-making and ensure accurate results.

What are the key skills and qualifications needed to thrive as a Statistical Programmer, and why are they important?

To thrive as a Statistical Programmer, you need strong expertise in statistics, programming languages like SAS or R, and a background in mathematics or computer science. Familiarity with statistical software, clinical data management systems, and regulatory standards such as CDISC is typically required. Attention to detail, problem-solving abilities, and effective communication are vital soft skills for collaborating with cross-functional teams. These skills ensure accurate data analysis, regulatory compliance, and successful project delivery in data-driven environments.

What is the difference between Statistical Programming vs Data Analysis?

AspectStatistical ProgrammingData Analysis
Primary FocusDeveloping and implementing statistical models and algorithmsInterpreting data to identify trends and insights
Skills & ToolsProgramming languages (SAS, R, Python), statistical methodsData visualization, descriptive statistics, Excel, SQL
Work EnvironmentPharmaceutical, biotech, or research settingsBusiness, marketing, healthcare sectors
CertificationsOften requires statistical or programming certificationsMay include data analysis or business analytics certifications

While both roles involve working with data, Statistical Programming primarily focuses on creating statistical models and algorithms using programming languages, often in research or clinical settings. Data Analysis emphasizes interpreting data to generate insights for decision-making across various industries. Understanding these differences helps professionals choose the right career path or job focus.

What are the most commonly searched types of Statistical Programming jobs in California? The most popular types of Statistical Programming jobs in California are:
What cities in California are hiring for Statistical Programming jobs? Cities in California with the most Statistical Programming job openings:
Statistical Programming jobs near you
Infographic showing various Statistical Programming job openings in California as of July 2026, with employment types broken down into 1% Internship, 81% Full Time, 13% Part Time, 2% Temporary, 2% Contract, and 1% Nights. Highlights an 89% Physical, 3% Hybrid, and 8% Remote job distribution, with an average salary of $145,363 per year, or $69.9 per hour.
Director of Statistical Programming

Director of Statistical Programming

Natera

San Francisco, CA • On-site, Remote

$186K - $233K/yr

Full-time

Medical, Dental, Vision, Life, Retirement

This job post has expired today. Applications are no longer accepted.

Natera rating

7.7

Company rating: 7.7 out of 10

Based on 35 frontline employees who took The Breakroom Quiz

51st of 105 rated laboratories

Job description

This is an exciting opportunity to lead Natera's Statistical Programming team, specifically focused on advancing our oncology portfolio through high-impact, practice-changing clinical trials. As a Director, you will provide strategic and technical oversight for all statistical programming activities supporting the clinical validation and utility of Natera's cutting-edge molecular diagnostics tests. The ideal candidate possesses a proven track record, strong leadership and communication skills, and a deep expertise in clinical trials, programming, and regulatory deliverables.
PRIMARY RESPONSIBILITIES:

Team Leadership: Build, mentor, and direct a high-performing statistical programming team, fostering technical excellence and overseeing their professional development.

Functional Oversight: Provide strategic direction and standards for the programming function, securing alignment with oncology clinical development goals and department infrastructure needs.

Submission Leadership: Act as the primary programming lead for regulatory submissions (e.g., 510(k), CTA/CDx, and PMA), ensuring all deliverables meet rigorous global standards.

Analysis & Reporting: Direct the generation and validation of analysis datasets and TLFs, ensuring data integrity and regulatory compliance with ICH, GCP, and FDA 21 CFR Part 11.

Development, Standards, and Validation: Lead the development, validation, and review of efficient R code to support statistical analyses and deliverables. Enforce departmental standards for programming maintenance and code integrity. Facilitate cross-functional standards (eCRF design, DMPs).

Infrastructure: Lead the development and maintenance of scalable programming infrastructure for the larger Biostatistics department.

Interdisciplinary Partnership: Partner with Biostatistics, Clinical Operations, Data Management, and Regulatory to integrate programming expertise into clinical study execution.

QUALIFICATIONS:

  • Minimum 10 years of relevant industry experience supporting clinical trials in diagnostics, biotechnology, pharmaceuticals, or related industries. At least 5 years leading a team.
  • Advanced degree in Biostatistics, Statistics, Computer Science, or a related field.

KNOWLEDGE, SKILLS, AND ABILITIES:

  • Expert working knowledge of R for clinical trial reporting; experience maintaining statistical packages and computing environments under version control
  • In-depth knowledge of CDISC standards including SDTM and ADaM
  • Proven track record of producing high-quality analysis output for regulatory audiences (FDA) and internal stakeholders.
  • Proven record of hiring, mentoring, and developing a successful, productive team
  • Demonstrated ability and enthusiasm for working on cross-functional teams with members of diverse technical backgrounds
  • Exceptional problem-solving skills and attention to detail
  • Prior experience with NGS, genetics, and/or oncology molecular diagnostic testing a plus
The pay range is listed and actual compensation packages are based on a wide array of factors unique to each candidate, including but not limited to skill set, years & depth of experience, certifications and specific office location. This may differ in other locations due to cost of labor considerations.
Remote USA
$186,400—$233,000 USD

OUR OPPORTUNITY

Natera™ is a global leader in cell-free DNA (cfDNA) testing, dedicated to oncology, women's health, and organ health. Our aim is to make personalized genetic testing and diagnostics part of the standard of care to protect health and enable earlier and more targeted interventions that lead to longer, healthier lives.

The Natera team consists of highly dedicated statisticians, geneticists, doctors, laboratory scientists, business professionals, software engineers and many other professionals from world-class institutions, who care deeply for our work and each other. When you join Natera, you'll work hard and grow quickly. Working alongside the elite of the industry, you'll be stretched and challenged, and take pride in being part of a company that is changing the landscape of genetic disease management.

WHAT WE OFFER

Competitive Benefits - Employee benefits include comprehensive medical, dental, vision, life and disability plans for eligible employees and their dependents. Additionally, Natera employees and their immediate families receive free testing in addition to fertility care benefits. Other benefits include pregnancy and baby bonding leave, 401k benefits, commuter benefits and much more. We also offer a generous employee referral program!

For more information, visit www.natera.com.

Natera is proud to be an Equal Opportunity Employer. We are committed to ensuring a diverse and inclusive workplace environment, and welcome people of different backgrounds, experiences, abilities and perspectives. Inclusive collaboration benefits our employees, our community and our patients, and is critical to our mission of changing the management of disease worldwide.

All qualified applicants are encouraged to apply, and will be considered without regard to race, color, religion, gender, gender identity or expression, sexual orientation, national origin, genetics, age, veteran status, disability or any other legally protected status. We also consider qualified applicants regardless of criminal histories, consistent with applicable laws.

If you are based in California, we encourage you to read this important information for California residents.

Link: https://www.natera.com/notice-of-data-collection-california-residents/

Please be advised that Natera will reach out to candidates with a @natera.com email domain ONLY. Email communications from all other domain names are not from Natera or its employees and are fraudulent. Natera does not request interviews via text messages and does not ask for personal information until a candidate has engaged with the company and has spoken to a recruiter and the hiring team. Natera takes cyber crimes seriously, and will collaborate with law enforcement authorities to prosecute any related cyber crimes.

For more information:
- BBB announcement on job scams
- FBI Cyber Crime resource page

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