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Staff Software Engineer Jobs in Boston, MA (NOW HIRING)

Asimov, Inc

Staff Software Engineer

Boston, MA · On-site

$179K - $230K/yr

We're looking for a Staff Software Engineer to help us build it. You'll join an interdisciplinary team that works directly with scientists, synthetic biologists, and computational biologists ...

Asimov

Staff Software Engineer

Boston, MA · Remote

$179K - $230K/yr

We're looking for a Staff Software Engineer to help us build it. You'll join an interdisciplinary team that works directly with scientists, synthetic biologists, and computational biologists ...

Tutor

Staff Software Engineer

Watertown, MA · On-site

They are seeking a Staff Software Engineer to lead the design and implementation of core software systems, focusing on building scalable and reliable platforms that support machine learning and ...

Tutor

Staff Software Engineer

Watertown, MA · On-site

The Staff Software Engineer will lead the design and implementation of core software systems, focusing on architecture and scalable platforms that support machine learning and robotics.

Xometry

Staff Software Engineer

Waltham, MA · Hybrid

Xometry is seeking a Staff Software Engineer to join our core machine learning and data platform engineering organization. In this role, you will partner closely with the AI leadership team to ...

Xometry

Staff Software Engineer

Waltham, MA · On-site

Xometry is seeking a Staff Software Engineer to join our core machine learning and data platform engineering organization. In this role, you will partner closely with the AI leadership team to ...

Xometry

Staff Software Engineer

Waltham, MA · Hybrid

Xometry is seeking a Staff Software Engineer to join our software engineering organization. In this role, you'll work as part of a skilled, collaborative team to build and maintain solutions for the ...

Proofpoint

Staff Software Engineer

Boston, MA · On-site

... Staff Software Engineer, Capture & Intelligence Platform Role Summary Nuclei is looking for a Staff Software Engineer to help lead the evolution of our Capture and Intelligence platform inside ...

Proofpoint, Inc.

Staff Software Engineer

Boston, MA · On-site

... Staff Software Engineer, Capture & Intelligence Platform Role Summary Nuclei is looking for a Staff Software Engineer to help lead the evolution of our Capture and Intelligence platform inside ...

Inmar

Staff Software Engineer

Boston, MA

The Staff Software Engineer provides technical leadership that spans multiple teams and business units within a division, ensuring architectural consistency, guiding cross-team initiatives, and ...

Onto

Staff Software Engineer

Wilmington, MA · On-site

$115K - $172K/yr

The Staff Software Engineer will play a key role in architecting and developing software that enables reliable wafer handling, robotics coordination, safety interlocks, motion control, system ...

Onto

Staff Software Engineer

Wilmington, MA

$115K - $172K/yr

The Staff Software Engineer will play a key role in architecting and developing software that enables reliable wafer handling, robotics coordination, safety interlocks, motion control, system ...

Anduril Industries

Staff Software Engineer

Boston, MA · On-site

They are seeking a Staff Software Engineer to lead technical direction and architectural standards for their QualityOS team, responsible for architecting and implementing mission-critical distributed ...

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Showing results 1-20

All JobsStaff Software Engineer JobsStaff Software Engineer Jobs in Boston, MA

Staff Software Engineer information

See Boston, MA salary details

$65.7K

$175.1K

$239K

How much do staff software engineer jobs pay per year?

As of Aug 2, 2026, the average yearly pay for staff software engineer in Boston, MA is $175,062.00, according to ZipRecruiter salary data. Most workers in this role earn between $146,100.00 and $206,900.00 per year, depending on experience, location, and employer.

How does a Staff Software Engineer typically contribute to setting technical direction within a team?

As a Staff Software Engineer, you are expected to play a pivotal role in shaping the technical roadmap and ensuring architectural consistency across projects. This often involves mentoring junior engineers, reviewing system designs, and making critical decisions on technology choices and best practices. You'll collaborate closely with product managers, engineering leads, and other stakeholders to align technical goals with business objectives. Your leadership helps foster innovation while maintaining high standards for code quality and system reliability.

What is the difference between Staff Software Engineer vs Senior Software Engineer?

AspectStaff Software EngineerSenior Software Engineer
Required CredentialsBachelor's or Master's in CS or related field; extensive experienceBachelor's or Master's in CS; significant experience
Work EnvironmentLeads projects, mentors teams, influences technical strategyDevelops features, solves complex problems, mentors juniors
Employer & Industry UsageCommon in large tech companies, enterprise environmentsWidespread across startups, mid-sized, and large companies

The main difference between a Staff Software Engineer and a Senior Software Engineer lies in scope and influence. Staff Engineers typically lead technical initiatives, mentor multiple teams, and shape engineering strategies, while Senior Engineers focus on developing features and solving complex problems within their teams. Both roles require strong technical skills, but Staff Engineers have a broader impact across projects and departments.

What Is a Staff Software Engineer?

A staff software engineer works on the technical team at an organization, typically under a senior management-level team member, to repair, develop, and maintain company software to ensure an efficient user experience. As a staff software engineer, your duties include finding and implementing solutions for issues, creating new software or applications by writing code, using visual development environments to debug, and ensuring the technical architecture runs smoothly. A significant aspect of your job is to not only contribute your skills but also mentor other software engineers to improve their skills and productivity.

What is a Staff Software Engineer?

A Staff Software Engineer is a senior-level technical role responsible for designing, developing, and overseeing complex software systems. They often serve as technical leaders within their teams, guiding architecture decisions, mentoring junior engineers, and collaborating across departments. Staff Software Engineers are expected to solve high-impact engineering problems, set technical standards, and ensure the quality and scalability of software products. Their role typically involves both hands-on coding and strategic planning to drive technological innovation within an organization.

What are the key skills and qualifications needed to thrive as a Staff Software Engineer, and why are they important?

To thrive as a Staff Software Engineer, you need deep expertise in software development, system architecture, and problem-solving, often supported by a relevant degree and significant industry experience. Mastery of programming languages (such as Java, Python, or C++), cloud platforms, version control systems, and familiarity with CI/CD pipelines are typically required. Exceptional leadership, strong communication, and mentorship abilities set candidates apart in this role. These skills are essential for designing scalable solutions, guiding technical teams, and ensuring the successful delivery of complex projects.
More about Staff Software Engineer jobs
What are the most commonly searched types of Staff Software Engineer jobs in Boston, MA? The most popular types of Staff Software Engineer jobs in Boston, MA are:
What are popular job titles related to Staff Software Engineer jobs in Boston, MA? For Staff Software Engineer jobs in Boston, MA, the most frequently searched job titles are:
What job categories do people searching Staff Software Engineer jobs in Boston, MA look for? The top searched job categories for Staff Software Engineer jobs in Boston, MA are:
What cities near Boston, MA are hiring for Staff Software Engineer jobs? Cities near Boston, MA with the most Staff Software Engineer job openings:
Staff Software Engineer jobs near you
Infographic showing various Staff Software Engineer job openings in Boston, MA as of July 2026, with employment types broken down into 92% Full Time, 4% Part Time, and 4% Contract. Highlights an 88% Physical, 5% Hybrid, and 7% Remote job distribution, with an average salary of $175,062 per year, or $84.2 per hour.

Staff Software Engineer

Asimov, Inc

Boston, MA • On-site

$179K - $230K/yr

Full-time

Re-posted 29 days ago

Job description

Our mission at Asimov is to advance humanity's ability to design living systems, enabling biotechnologies with outsized benefit to society. We're developing a mammalian synthetic biology platform--from cells to software--to enable the design and manufacture of next-generation therapeutics.
What would software engineering be like without an IDE? How could humans design a modern plane without CAD? Genetic engineering will be even more demanding-and we're building the tools to make it possible. Kernel is our platform for bioengineers to design, build, and debug genetic systems as confidently as we ship code. We're looking for a Staff Software Engineer to help us build it.
You'll join an interdisciplinary team that works directly with scientists, synthetic biologists, and computational biologists alongside your teammates in software engineering and product.
About the Role:
  • Make architectural decisions that will shape Kernel for years, with real ownership over how the system evolves.
  • Design GraphQL APIs for searching, editing and analyzing tens of thousands of genetic constructs using Python 3, SQLAlchemy and Strawberry.
  • Architect data models that represent the genuine complexity of biological systems.
  • Interface directly with synthetic biologists to understand their workflows and identify tools that would transform their productivity.
  • Be part of an on-call rotation to support the software you've helped develop.

About You:
  • You have 10+ years building production software - systems that other engineers depend on, not research code that runs once.
  • You have deep expertise in Python 3, and ideally with GraphQL, SQLAlchemy, and/or Strawberry.
  • You're the kind of engineer who loses track of time working on an interesting technical problem. You want challenges that will have you waking up with a new idea that you can't wait to try.
  • You think about API design, data migrations, and what happens when the system has 10x usage.
  • You want to help design a product with a close-knit team, not just write code from predefined specifications. You can navigate the ambiguity of building something first-of-its-kind.

We're fueled by a vision to transform biological engineering into a fully-fledged engineering discipline. Should you join our team, you will grow with a constantly evolving organization and push the frontiers of synthetic biology. Company culture is key to Asimov, and ours is a culture of recombination; we believe that our mission can only be achieved by bringing together a diverse team with a mixture of backgrounds and perspectives.

Apply