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Sr Python Engineer Jobs in North Carolina (NOW HIRING)

Sarian, Inc.

Sr. Python Web Developer

Charlotte, NC · On-site

$118K - $159K/yr

Role: Sr. Python Web Developer/Only USC & GC Location: Charlotte, NC Onsite position Fulltime position *****NO C2C***** JD Skill: Sr. Python Web Developer * 9 - 14 Years of experience as Sr.Python ...

Sarian, Inc.

Sr. Python Web Developer

Charlotte, NC · On-site

$118K - $159K/yr

Role: Sr. Python Web Developer Location: Charlotte, NC Onsite position Fulltime position JD Skill: Sr. Python Web Developer * 9 - 14 Years of experience as Sr.Python Web Developer * Expert in Python ...

Sarian, Inc.

Sr. Python Web Developer

Charlotte, NC · On-site

$118K - $159K/yr

Role: Sr. Python Web Developer Location: Charlotte, NC Onsite position Fulltime position *****NO C2C***** JD Skill: Sr. Python Web Developer Must Have Technical/Functional Skills: * Expert in Python ...

Laiba Technologies LLC

Python Developer

Charlotte, NC · On-site

$49 - $67.75/hr

Senior Python & MongoDB Engineer We are looking for a Senior Python & MongoDB Engineer with strong hands-on experience building and supporting high-volume, scalable, mission-critical applications ...

Accord Technologies Inc.

Python developer

Charlotte, NC · On-site

$49 - $67.75/hr

Sr Python developer Work Location : Charlotte NC Face to Face interview needed in charlotte NC 12 months Position type; W2 contract. About the Role: We are seeking a talented Python Developer to join ...

CIS Technologies Inc.

Lead Python Developer

Charlotte, NC · On-site

$136K - $168K/yr

Wells Fargo / Mphasis Experience: 12+ years We are looking for a Senior Python Developer with strong experience in AWS, Terraform, and AI/ML to design and develop scalable cloud-native applications ...

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Sr Python Engineer information

What does a Sr Python Engineer do?

A Sr Python Engineer is an experienced software developer who specializes in designing, developing, and maintaining applications using the Python programming language. They often lead projects, mentor junior engineers, and work on complex problems that require deep technical expertise. Their responsibilities may include writing efficient code, optimizing performance, integrating with APIs or databases, and ensuring the overall quality of software solutions. Additionally, they may collaborate with cross-functional teams to deliver robust and scalable applications.

What are the key skills and qualifications needed to thrive as a Sr Python Engineer?

To thrive as a Sr Python Engineer, you need advanced proficiency in Python programming, strong knowledge of software design patterns, and experience with scalable application development, often supported by a degree in computer science or related field. Familiarity with frameworks like Django or Flask, version control systems such as Git, and cloud platforms like AWS or Azure is typically required, with certifications in cloud or Python development considered a plus. Excellent problem-solving abilities, strong communication, and leadership skills help you collaborate effectively and mentor junior engineers. These competencies are critical for delivering robust, efficient solutions and driving technical excellence within development teams.

What are some common challenges Sr Python Engineers face when working on large-scale applications?

Sr Python Engineers often encounter challenges related to maintaining code quality and scalability as applications grow. Managing dependencies, ensuring optimal performance, and coordinating with cross-functional teams can be complex, especially in distributed systems. Additionally, integrating new technologies or frameworks while maintaining backward compatibility requires careful planning and communication. Proactive code reviews, clear documentation, and collaborative problem-solving are essential to overcoming these challenges.

What is the difference between Sr Python Engineer vs Python Developer?

AspectSr Python EngineerPython Developer
Required CredentialsBachelor's degree in CS or related field, experience in Python, often some leadership skillsBachelor's degree in CS or related field, strong Python skills, often less emphasis on leadership
Work EnvironmentTeam lead, project architect, involved in system design and optimizationCode writing, feature development, bug fixing
Employer & Industry UsageTech companies, startups, enterprise softwareWeb development, data analysis, automation projects

While both roles require strong Python skills, Sr Python Engineers typically have more experience, leadership responsibilities, and involvement in system architecture, whereas Python Developers focus more on coding and feature implementation.

What are popular job titles related to Sr Python Engineer jobs in North Carolina?

For Sr Python Engineer jobs in North Carolina, the most frequently searched job titles are:

What job categories do people searching Sr Python Engineer jobs in North Carolina look for?

The top searched job categories for Sr Python Engineer jobs in North Carolina are:

Sr Python Engineer jobs near you
Infographic showing various Sr Python Engineer job openings in North Carolina as of August 2026, with employment types broken down into 95% Full Time, 2% Part Time, and 3% Contract. Highlights an 85% Physical, 5% Hybrid, and 10% Remote job distribution.

Sr. Python Developer

Durham, NC • On-site

Indotronix International Corporation
Recruiting and Staffing Services • 1 - 5K employees
Learn more about Indotronix International Corporationexternal

$114K - $154K/yr

Full-time, Contractor

Re-posted 12 days ago

Job description

Sr. Python Developer (Remote, Contract-to-Hire)
Durham, NC | 6-Month Contract-to-Hire | No Visa Sponsorship
About the Role
Join a forward-thinking engineering team as a Sr. Python Developer, supporting mission-critical systems that drive lab order intake, processing, and interpretation. In this high-impact, fully remote position, you'll solve complex, ambiguous problems, lead key integration projects, and set the technical standard for a collaborative, globally distributed team. This is a contract-to-hire opportunity for professionals authorized to work in the U.S. without sponsorship.
Responsibilities
- Own and deliver end-to-end projects across product and platform teams
- Design, build, and maintain a central monolithic system using Python and Django
- Develop robust API-driven system integrations with a strong backend focus
- Modernize and stabilize core platform functionality for long-term scalability
- Provide production support and participate in on-call rotations
- Mentor junior engineers and elevate team performance through technical leadership
- Communicate technical solutions clearly to stakeholders across technical levels
Required Skills and Experience
- 7+ years of professional software engineering experience
- Advanced proficiency in Python and Django
- Strong backend/full-stack development experience, including API design
- Solid TypeScript skills (front and backend development)
- Experience working with MySQL databases
- Demonstrated expertise in system architecture and integration
- Authorized to work in the U.S. without current or future sponsorship
Preferred Skills
- Experience in healthcare, clinical laboratory, or genomics technology
- Familiarity with AWS-native environments and cloud platforms
- Exposure to containerization, Kubernetes, or infrastructure-as-code (e.g., Terraform)
- Experience designing and maintaining multi-consumer API platforms
- Knowledge of AI tools (e.g., Claude, Codex)
Benefits
- Competitive contract compensation with potential for full-time hire
- 100% remote work; collaborate with a distributed, innovative engineering team
- Opportunity to work on cutting-edge, impactful systems in the health tech space
- Fast-paced environment with mentorship and career growth opportunities
How to Apply
Ready to elevate your career and technical impact? Apply now with your resume and a summary of relevant experience.
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About Indotronix

Sourced by ZipRecruiter

In 1986, Indotronix established itself in the staffing space. 22 years later, Avani entered the scene, offering consulting and technology development. Finally, in 2016, the two joined forces to begin delivering talent across all areas, from Staffing to Consulting to unique platform development.

Industry

Recruiting and staffing services

Company size

1,001 - 5,000 Employees

Headquarters location

Rochester, NY, US

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