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Sr Python Developer Jobs in North Carolina (NOW HIRING)

Senior Python Developer

Charlotte, NC ยท On-site

$68.25/hr

Job Title: Application Programmer III - Senior Python Developer Location: Jersey City, NJ Duration: Contract - 12 months Pay Range: $68.25/hr (W2) Job ID: 373452 About BCforward BCforward is a ...

Senior Python Developer

Durham, NC ยท On-site

$117K - $158K/yr

Job Summary The Senior Python Developer is responsible for designing, developing, and maintaining mission-critical enterprise applications with a strong focus on backend development, API integrations ...

Python developer

Charlotte, NC ยท On-site

$49 - $67.75/hr

Sr Python developer Work Location : Charlotte NC Face to Face interview needed in charlotte NC 12 months Position type; W2 contract. About the Role: We are seeking a talented Python Developer to join ...

Sr. Python Web Developer

Charlotte, NC ยท On-site

$118K - $159K/yr

Role: Sr. Python Web Developer/Only USC & GC Location: Charlotte, NC Onsite position Fulltime position *****NO C2C***** JD Skill: Sr. Python Web Developer * 9 - 14 Years of experience as Sr.Python ...

Sr. Python Web Developer

Charlotte, NC ยท On-site

$118K - $159K/yr

Role: Sr. Python Web Developer Location: Charlotte, NC Onsite position Fulltime position JD Skill: Sr. Python Web Developer * 9 - 14 Years of experience as Sr.Python Web Developer * Expert in Python ...

Sr. Python Web Developer

Charlotte, NC ยท On-site

$118K - $159K/yr

Role: Sr. Python Web Developer Location: Charlotte, NC Onsite position Fulltime position *****NO C2C***** JD Skill: Sr. Python Web Developer Must Have Technical/Functional Skills: * Expert in Python ...

Sr .Net Python Developer

Charlotte, NC ยท On-site

$118K - $159K/yr

Job Title: Sr .Net Python Developer Job Location: Charlotte, NC Job Type: Contract * Candidate should have 10+ years of experience in below technologies. * Microsoft Technologies C# ASPNET Core ...

Python Developer AI/ML

Charlotte, NC ยท On-site

$49 - $67.75/hr

Python Developer - AI/ML Location: Charlotte, NC or Irving, TX Contract Interview Process: Final ... In this role, you will work closely with Senior Engineers, leads, and product teams to design ...

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Sr Python Developer information

See North Carolina salary details

$50K

$129K

$177.2K

How much do sr python developer jobs pay per year?

As of Jul 9, 2026, the average yearly pay for sr python developer in North Carolina is $129,028.00, according to ZipRecruiter salary data. Most workers in this role earn between $110,400.00 and $148,600.00 per year, depending on experience, location, and employer.

What are the typical daily responsibilities of a Sr Python Developer?

As a Sr Python Developer, your daily tasks often include designing and coding complex features, reviewing code from team members, and troubleshooting bugs or performance issues. You may also lead technical discussions, contribute to architectural decisions, and collaborate closely with product managers, QA engineers, and other developers. Mentoring junior team members and staying up to date with best practices or new technologies is also a regular part of the role. This combination of hands-on engineering and leadership responsibilities ensures both the quality of the codebase and the continual growth of the team.

What are the key skills and qualifications needed to thrive in the Sr Python Developer position, and why are they important?

To thrive as a Sr Python Developer, you need expert proficiency in Python programming, strong problem-solving skills, and a solid background in computer science or related fields, often demonstrated by several years of relevant experience. Familiarity with frameworks like Django or Flask, version control systems such as Git, and sometimes certifications such as PCEP or PCAP are typically valued. Strong communication, leadership, and the ability to mentor junior developers are standout soft skills for this position. These combined proficiencies ensure that Sr Python Developers can build robust solutions, contribute to architectural decisions, and drive team success in complex technical environments.

What is a Sr Python Developer job?

A Sr Python Developer is an experienced software engineer who specializes in designing, developing, and maintaining applications using Python. They are responsible for writing clean, efficient, and scalable code while also mentoring junior developers and collaborating with cross-functional teams. Their role often includes optimizing application performance, integrating third-party services, and ensuring best coding practices. Additionally, they may work with frameworks like Django or Flask and databases such as PostgreSQL or MongoDB to build robust backend systems.

Infographic showing various Sr Python Developer job openings in North Carolina as of July 2026, with employment types broken down into 33% Full Time, and 67% Contract. Highlights an 78% In-person, 11% Hybrid, and 11% Remote job distribution, with an average salary of $129,028 per year, or $62 per hour.
Sr. Python Developer

$117K - $158K/yr

Full-time, Contractor

Posted 10 days ago


Job description

Sr. Python Developer | Durham, North Carolina, United States Sr. Python Developer (Remote, Contract-to-Hire) Durham, NC | 6-Month Contract-to-Hire | No Visa Sponsorship About the Role Join a forward-thinking engineering team as a Sr. Python Developer, supporting mission-critical systems that drive lab order intake, processing, and interpretation. In this high-impact, fully remote position, you'll solve complex, ambiguous problems, lead key integration projects, and set the technical standard for a collaborative, globally distributed team. This is a contract-to-hire opportunity for professionals authorized to work in the U.S. without sponsorship. Responsibilities - Own and deliver end-to-end projects across product and platform teams - Design, build, and maintain a central monolithic system using Python and Django - Develop robust API-driven system integrations with a strong backend focus - Modernize and stabilize core platform functionality for long-term scalability - Provide production support and participate in on-call rotations - Mentor junior engineers and elevate team performance through technical leadership - Communicate technical solutions clearly to stakeholders across technical levels Required Skills and Experience - 7+ years of professional software engineering experience - Advanced proficiency in Python and Django - Strong backend/full-stack development experience, including API design - Solid TypeScript skills (front and backend development) - Experience working with MySQL databases - Demonstrated expertise in system architecture and integration - Authorized to work in the U.S. without current or future sponsorship Preferred Skills - Experience in healthcare, clinical laboratory, or genomics technology - Familiarity with AWS-native environments and cloud platforms - Exposure to containerization, Kubernetes, or infrastructure-as-code (e.g., Terraform) - Experience designing and maintaining multi-consumer API platforms - Knowledge of AI tools (e.g., Claude, Codex) Benefits - Competitive contract compensation with potential for full-time hire - 100% remote work; collaborate with a distributed, innovative engineering team - Opportunity to work on cutting-edge, impactful systems in the health tech space - Fast-paced environment with mentorship and career growth opportunities How to Apply Ready to elevate your career and technical impact? Apply now with your resume and a summary of relevant experience.

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About Indotronix

Sourced by ZipRecruiter

In 1986, Indotronix established itself in the staffing space. 22 years later, Avani entered the scene, offering consulting and technology development. Finally, in 2016, the two joined forces to begin delivering talent across all areas, from Staffing to Consulting to unique platform development.

Industry

Recruiting and staffing services

Company size

1,001 - 5,000 Employees

Headquarters location

Rochester, NY, US