1

Sr Python Developer Jobs in North Carolina (NOW HIRING)

Sr. Python Developer

Durham, NC ยท On-site

$110K - $148K/yr

  • Medical

  • Dental

  • Vision

  • Life

  • Retirement

Job#: 3039740 Sr. Python Developer Location: Durham, North Carolina - Hybrid, 3x per week onsite Duration : 6 Month Contract to Hire Role Overview We are seeking a Senior Software Engineer to support ...

Python developer

Charlotte, NC ยท On-site

$49 - $67.75/hr

Sr Python developer Work Location : Charlotte NC Face to Face interview needed in charlotte NC 12 months Position type; W2 contract. About the Role: We are seeking a talented Python Developer to join ...

Sr. Python Web Developer

Charlotte, NC ยท On-site

$118K - $159K/yr

Role: Sr. Python Web Developer Location: Charlotte, NC Onsite position Fulltime position JD Skill: Sr. Python Web Developer * 9 - 14 Years of experience as Sr.Python Web Developer * Expert in Python ...

Sr. Python Web Developer

Charlotte, NC ยท On-site

$118K - $159K/yr

Role: Sr. Python Web Developer/Only USC & GC Location: Charlotte, NC Onsite position Fulltime position *****NO C2C***** JD Skill: Sr. Python Web Developer * 9 - 14 Years of experience as Sr.Python ...

Sr. Python Web Developer

Charlotte, NC ยท On-site

$118K - $159K/yr

Role: Sr. Python Web Developer Location: Charlotte, NC Onsite position Fulltime position *****NO C2C***** JD Skill: Sr. Python Web Developer Must Have Technical/Functional Skills: * Expert in Python ...

Sr .Net Python Developer

Charlotte, NC ยท On-site

$118K - $159K/yr

Job Title: Sr .Net Python Developer Job Location: Charlotte, NC Job Type: Contract * Candidate should have 10+ years of experience in below technologies. * Microsoft Technologies C# ASPNET Core ...

Sr. Python AI developer

Charlotte, NC ยท On-site

$118K - $159K/yr

... seeking a Senior Software Engineer with strong backend Python development experience and proven expertise in delivering AI-driven solutions. The ideal candidate will have experience building ...

Python Developer AI/ML

Charlotte, NC ยท On-site

$49 - $67.75/hr

Python Developer - AI/ML Location: Charlotte, NC or Irving, TX Contract Interview Process: Final ... In this role, you will work closely with Senior Engineers, leads, and product teams to design ...

Senior AI Developer

Raleigh, NC ยท On-site

$118K - $158K/yr

NCDIT-T Web Systems is seeking a Senior AI Enablement Engineer with strong experience in C#, Vue.js, Python, and Azure AI . The role focuses on integrating Azure OpenAI, Copilot Studio, and other AI ...

next page

Showing results 1-20

Sr Python Developer information

See North Carolina salary details

$50K

$129K

$177.2K

How much do sr python developer jobs pay per year?

As of Aug 18, 2026, the average yearly pay for sr python developer in North Carolina is $129,028.00, according to ZipRecruiter salary data. Most workers in this role earn between $110,400.00 and $148,600.00 per year, depending on experience, location, and employer.

What is a Sr Python Developer?

A Sr Python Developer is an experienced software engineer who specializes in designing, developing, and maintaining applications using Python. They are responsible for writing clean, efficient, and scalable code while also mentoring junior developers and collaborating with cross-functional teams. Their role often includes optimizing application performance, integrating third-party services, and ensuring best coding practices. Additionally, they may work with frameworks like Django or Flask and databases such as PostgreSQL or MongoDB to build robust backend systems.

What are the typical daily responsibilities of a Sr Python Developer?

As a Sr Python Developer, your daily tasks often include designing and coding complex features, reviewing code from team members, and troubleshooting bugs or performance issues. You may also lead technical discussions, contribute to architectural decisions, and collaborate closely with product managers, QA engineers, and other developers. Mentoring junior team members and staying up to date with best practices or new technologies is also a regular part of the role. This combination of hands-on engineering and leadership responsibilities ensures both the quality of the codebase and the continual growth of the team.

What are the key skills and qualifications needed to thrive in the Sr Python Developer position, and why are they important?

To thrive as a Sr Python Developer, you need expert proficiency in Python programming, strong problem-solving skills, and a solid background in computer science or related fields, often demonstrated by several years of relevant experience. Familiarity with frameworks like Django or Flask, version control systems such as Git, and sometimes certifications such as PCEP or PCAP are typically valued. Strong communication, leadership, and the ability to mentor junior developers are standout soft skills for this position. These combined proficiencies ensure that Sr Python Developers can build robust solutions, contribute to architectural decisions, and drive team success in complex technical environments.

What are popular job titles related to Sr Python Developer jobs in North Carolina?

For Sr Python Developer jobs in North Carolina, the most frequently searched job titles are:

What job categories do people searching Sr Python Developer jobs in North Carolina look for?

The top searched job categories for Sr Python Developer jobs in North Carolina are:

Infographic showing various Sr Python Developer job openings in North Carolina as of August 2026, with employment types broken down into 33% Full Time, and 67% Contract. Highlights an 78% In-person, 11% Hybrid, and 11% Remote job distribution, with an average salary of $129,028 per year, or $62 per hour.

Sr. Python Developer

Apex Systems

Durham, NC โ€ข On-site

$110K - $148K/yr

Other

Medical, Dental, Vision, Life, Retirement

This job post hasย expired today.ย Applications are no longer accepted.


Job description

Job#: 3039740
Job Description:
Sr. Python Developer
Location: Durham, North Carolina - Hybrid, 3x per week onsite
Duration: 6 Month Contract to Hire
Role Overview
We are seeking a Senior Software Engineer to support a core monolithic system that orchestrates lab order intake, processing, and interpretation. This role requires an individual who can take ambiguous, complex problems and drive them to completion. The successful candidate will act as a technical leader, mentoring other engineers and raising the bar for the team in architecture and execution, with a heavy focus on integration work connecting internal systems with lab pipelines.
Key Responsibilities
  • Own and deliver projects across product, platform, and stakeholder teams.
  • Design, develop, and maintain a central, monolithic system built on Python and Django.
  • Develop and enhance system integrations and core platform functionality with a strong emphasis on API-driven architecture.
  • Perform foundational engineering work focused on system improvements, stability, and modernization.
  • Provide production support, including participating in an on-call rotation and troubleshooting bugs.
  • Mentor teammates and elevate the team's technical execution standards.
  • Communicate clearly with both technical and non-technical audiences.
Required Qualifications
Experience: A minimum of 7+ years of professional software engineering experience is required. Candidates must demonstrate strong experience in system design, development, and real-world application architecture.
Technical Skills: Proficiency in Python and Django is mandatory. Candidates must have full-stack experience with a strong backend emphasis, including heavy API development and experience with TypeScript and MySQL.
Education: A formal degree is not required. Experience and technical skill are prioritized.
Preferred Qualifications
  • Experience in healthcare technology, clinical laboratory, or genomics industries.
  • Knowledge of AWS-native environments and cloud platforms.
  • Familiarity with containerization, Kubernetes, or infrastructure-as-code tools like Terraform.
  • Experience designing and maintaining API platforms that serve multiple internal consumers.
  • Familiarity with AI development tools such as Claude or Codex.
Work Environment
This is a fully remote position. The team is collaborative and engineers are expected to contribute ideas and participate in design decisions. The team is globally distributed across multiple time zones.
Eligibility
Visa sponsorship is not available for this position now or in the future.
Everforth Apex is a world-class IT services company that serves thousands of clients across the globe. When you join Everforth Apex, you become part of a team that values innovation, collaboration, and continuous learning. We offer quality career resources, training, certifications, development opportunities, and a comprehensive benefits package. Our commitment to excellence is reflected in many awards, including ClearlyRateds Best of Staffing in Talent Satisfaction in the United States and Great Place to Work in the United Kingdom and Mexico.
Everforth Apex uses a virtual recruiter as part of the application process. Click for more details. By applying for this job, you agree to receive calls, AI-generated calls, text messages, or emails from Everforth Apex and its affiliates, and contracted partners. Frequency varies for text messages. Message and data rates may apply. Carriers are not liable for delayed or undelivered messages. You can reply STOP to cancel and HELP for help. You can access our privacy policy at
Everforth Apex Benefits Overview: Everforth Apex offers a range of supplemental benefits, including medical, dental, vision, life, disability, and other insurance plans that offer an optional layer of financial protection. We offer an ESPP (employee stock purchase program) and a 401K program which allows you to contribute typically within 30 days of starting, with a company match after 12 months of tenure. Everforth Apex also offers a HSA (Health Savings Account on the HDHP plan), a SupportLinc Employee Assistance Program (EAP) with up to 8 free counseling sessions, a corporate discount savings program and other discounts. In terms of professional development, Everforth Apex hosts an on-demand training program, provides access to certification prep and a library of technical and leadership courses/books/seminars once you have 6+ months of tenure, and certification discounts and other perks to associations that include CompTIA and IIBA. Everforth Apex has a dedicated customer service team for our Consultants that can address questions around benefits and other resources, as well as a certified Career Coach. You can access a full list of our benefits, programs, support teams and resources within our 'Welcome Packet' as well, which an Everforth Apex team member can provide.
Everforth Apex Systems is an equal opportunity employer. We do not discriminate or allow discrimination on the basis of race, color, religion, creed, sex (including pregnancy, childbirth, breastfeeding, or related medical conditions), age, sexual orientation, gender identity, national origin, ancestry, citizenship, genetic information, registered domestic partner status, marital status, disability, status as a crime victim, protected veteran status, political affiliation, union membership, or any other characteristic protected by law. Everforth Apex will consider qualified applicants with criminal histories in a manner consistent with the requirements of applicable law.
If you require an accommodation under the Americans with Disabilities Act to participate in an interview with a virtual recruiter or to use our website for a search or application, please contact our Benefits Department at or . Please note that this contact information is strictly to be used for medical ADA accommodations and that no other inquiries will be answered.
UnitedHealthcare creates and publishes the Transparency in Coverage Machine-Readable Files on behalf of Everforth Apex Systems.