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Sr Python Developer Jobs in North Carolina (NOW HIRING)

ClinDCast, LLC

Senior AI Developer

Raleigh, NC · On-site

$118K - $158K/yr

NCDIT-T Web Systems is seeking a Senior AI Enablement Engineer with strong experience in C#, Vue.js, Python, and Azure AI . The role focuses on integrating Azure OpenAI, Copilot Studio, and other AI ...

Xylem

Senior Software Engineer (Python/Django)

Charlotte, NC · On-site

$118K - $159K/yr

The Role As a Senior Software Engineer , you will join Xylem's Business Automation team, where we ... Strong experience developing applications with Django, Flask, FastAPI, or similar Python frameworks

New

DevCare Solutions

Python Developer

Raleigh, NC · On-site

$48.75 - $67.25/hr

Strong hands on experience with Python Proficiency with Power BI Strong SQL skills and experience working with relational databases (SQL Server, PostgreSQL, Oracle, MySQL, Ingres) • Senior level ...

New

1 point system

Python DevOps Engineer

Charlotte, NC · On-site

Client is seeking a mid-level to senior engineer to join client's team on a contract basis to help ... Core Skills: * Strong Python development skills for enterprise-scale automation and service ...

TEKsystems

Full Stack Python Developer

Charlotte, NC

$70 - $73/hr

Description seeking a Senior full stack Developer with strong technical leadership and a proactive ... Skills Python React AI experience Job Type & Location This is a Contract position based out of ...

TEKsystems

Full Stack Python Developer

Charlotte, NC

$70 - $73/hr

Description seeking a Senior full stack Developer with strong technical leadership and a proactive ... Skills Python React AI experience Job Type & Location This is a Contract position based out of ...

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Sr Python Developer information

See North Carolina salary details

$50K

$129K

$177.2K

How much do sr python developer jobs pay per year?

As of Aug 19, 2026, the average yearly pay for sr python developer in North Carolina is $129,028.00, according to ZipRecruiter salary data. Most workers in this role earn between $110,400.00 and $148,600.00 per year, depending on experience, location, and employer.

What is a Sr Python Developer?

A Sr Python Developer is an experienced software engineer who specializes in designing, developing, and maintaining applications using Python. They are responsible for writing clean, efficient, and scalable code while also mentoring junior developers and collaborating with cross-functional teams. Their role often includes optimizing application performance, integrating third-party services, and ensuring best coding practices. Additionally, they may work with frameworks like Django or Flask and databases such as PostgreSQL or MongoDB to build robust backend systems.

What are the typical daily responsibilities of a Sr Python Developer?

As a Sr Python Developer, your daily tasks often include designing and coding complex features, reviewing code from team members, and troubleshooting bugs or performance issues. You may also lead technical discussions, contribute to architectural decisions, and collaborate closely with product managers, QA engineers, and other developers. Mentoring junior team members and staying up to date with best practices or new technologies is also a regular part of the role. This combination of hands-on engineering and leadership responsibilities ensures both the quality of the codebase and the continual growth of the team.

What are the key skills and qualifications needed to thrive in the Sr Python Developer position, and why are they important?

To thrive as a Sr Python Developer, you need expert proficiency in Python programming, strong problem-solving skills, and a solid background in computer science or related fields, often demonstrated by several years of relevant experience. Familiarity with frameworks like Django or Flask, version control systems such as Git, and sometimes certifications such as PCEP or PCAP are typically valued. Strong communication, leadership, and the ability to mentor junior developers are standout soft skills for this position. These combined proficiencies ensure that Sr Python Developers can build robust solutions, contribute to architectural decisions, and drive team success in complex technical environments.

What are popular job titles related to Sr Python Developer jobs in North Carolina?

For Sr Python Developer jobs in North Carolina, the most frequently searched job titles are:

What job categories do people searching Sr Python Developer jobs in North Carolina look for?

The top searched job categories for Sr Python Developer jobs in North Carolina are:

Sr Python Developer jobs near you
Infographic showing various Sr Python Developer job openings in North Carolina as of August 2026, with employment types broken down into 33% Full Time, and 67% Contract. Highlights an 78% In-person, 11% Hybrid, and 11% Remote job distribution, with an average salary of $129,028 per year, or $62 per hour.

Senior AI Developer

ClinDCast, LLC

Raleigh, NC • On-site

$118K - $158K/yr

Other

Posted 8 days ago

Job description

Job Summary:
NCDIT-T Web Systems is seeking a Senior AI Enablement Engineer with strong experience in C#, Vue.js, Python, and Azure AI. The role focuses on integrating Azure OpenAI, Copilot Studio, and other AI capabilities into enterprise applications while ensuring secure, scalable, and compliant implementations.
Key Responsibilities:
  • Develop AI integrations using C#, Vue.js, Python, and Azure services.
  • Implement Azure OpenAI and Copilot Studio in new and existing applications.
  • Guide development teams on AI integration, prompt engineering, API design, and secure AI adoption.
  • Design scalable and high-performance AI workloads on Azure.
  • Collaborate with DevOps/SRE teams on observability, governance, and best practices.
  • Support modernization and migration of .NET/C#/Vue.js/Python applications to Azure.
Required Skills:
  • 3+ years of experience integrating Azure OpenAI, Copilot Studio, and AI into enterprise applications.
  • Experience with security configuration, APIM, and AI usage limits.
  • 2+ years guiding application teams on AI integration strategies.
  • Strong development experience with C#, Vue.js, Python, and Azure.
Preferred Skills:
  • Experience scaling AI workloads.
  • Experience modernizing/re-platforming applications to Azure.
  • Bicep/Terraform and Azure infrastructure automation.
  • Azure DevOps and CI/CD pipelines.
  • Azure certifications such as AI-102, AZ-105, AZ-305, or AZ-400
 
Local Candidates: Must be local to the Triangle region of North Carolina. Locations are Raleigh, Durham, Chapel Hill
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About ClinDCast

Sourced by ZipRecruiter

ClinDCast is at the forefront of shaping the future of healthcare by partnering with globally recognized healthcare organizations and offering them innovative solutions and expert guidance. Our suite of services is designed to cater to a broad range of needs of healthcare organizations, including healthcare IT innovation, electronic health record (EHR) implementation & optimizations, data conversion, regulatory and quality reporting, enterprise data analytics, FHIR interoperability strategy, payer-to-payer data exchange, and application programming interface (API) strategy. With 15+ Years Of Healthcare IT Industry Experience, ClinDCast Is A Trusted Partner For Payers, Providers, And Lifesciences Organizations, Enabling Them To Deliver Exceptional Product And Solutions For Their Customers.

Industry

Health care and social assistance

Company size

11 - 50 Employees

Headquarters location

Wesley Chapel, FL, US

Social media

Twitter

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