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Solubility Jobs (NOW HIRING)

Celmark International

R&D Formulator

Orlando, FL · On-site

... solubility, stability, and flavor systems in liquid applications · Demonstrated ability to take products from concept through commercialization · Experience scaling formulations into manufacturing ...

CSBio

Technician, GMP Production

Milpitas, CA · On-site

$20 - $25/hr

Identify the fully protected 20 amino acids batch by batch in terms of solubility and appearance * Operate laboratory equipment and instruments including: HPLCs, centrifuges, freeze dryers, stir ...

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Solubility information

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$35K

$87.7K

$148K

How much do solubility jobs pay per year?

As of Aug 10, 2026, the average yearly pay for solubility in the United States is $87,733.00, according to ZipRecruiter salary data. Most workers in this role earn between $59,000.00 and $110,000.00 per year, depending on experience, location, and employer.

What are the key skills and qualifications needed to thrive as a solubility scientist, and why are they important?

To thrive as a Solubility Scientist, you need a strong background in chemistry or pharmaceutical sciences, with expertise in analytical techniques and a relevant degree. Familiarity with laboratory instruments such as HPLC, UV-Vis spectrophotometry, and solubility testing equipment, along with knowledge of quality and safety standards, is typically required. Attention to detail, problem-solving abilities, and effective communication are vital soft skills for this role. These competencies ensure accurate experimental outcomes, support drug development or material science research, and facilitate clear reporting of findings.

What does a solubility scientist do?

A solubility scientist studies how substances dissolve in various solvents, determining the conditions and factors that affect solubility. They are often employed in industries such as pharmaceuticals, chemicals, and food science to optimize formulations and ensure product stability. Their work involves conducting experiments, analyzing data, and developing new methods to improve the solubility of compounds. This role is crucial for drug development, as the solubility of a compound can affect its efficacy and delivery. Solubility scientists typically have backgrounds in chemistry, chemical engineering, or related fields.

What are some common challenges faced by solubility scientists when optimizing drug formulations, and how are these typically addressed?

Solubility scientists often encounter challenges such as poor aqueous solubility of drug candidates, which can limit bioavailability and therapeutic effectiveness. To address these, they routinely collaborate with formulation chemists and analytical teams to explore techniques like salt formation, particle size reduction, and the use of solubilizing excipients. Regular communication within cross-functional teams is essential to troubleshoot issues and adapt strategies based on experimental data. Staying updated with emerging technologies and regulatory guidelines also plays a vital role in overcoming these challenges.

What is the difference between Solubility vs Chemist?

AspectSolubilityChemist
Required CredentialsHigh school diploma or equivalent; often a degree in chemistry or related fieldBachelor's degree in chemistry or related field; advanced roles may require a master's or PhD
Work EnvironmentLaboratories, manufacturing plants, research facilitiesLaboratories, research institutions, industry settings
Industry UsageUsed in chemistry, pharmaceuticals, materials science to describe substance behaviorProfessionals conducting chemical research, analysis, and development

Solubility refers to a substance's ability to dissolve in a solvent, a key concept in chemistry and material sciences. A chemist is a professional who studies, analyzes, and develops chemical substances, often applying knowledge of solubility. While solubility is a scientific property, a chemist uses this property in practical applications. Understanding the difference helps clarify that solubility is a concept, whereas a chemist is a role that utilizes such concepts in various industries.

More about Solubility jobs
What job categories do people searching Solubility jobs look for? The top searched job categories for Solubility jobs are:
Solubility jobs near you
Infographic showing various Solubility job openings in the United States as of August 2026, with employment types broken down into 31% Full Time, 66% Part Time, 1% Temporary, and 2% Contract. Highlights an 34% Physical, and 66% Remote job distribution, with an average salary of $87,733 per year, or $42.2 per hour.

Scientist / Senior Scientist, Protein Engineering

Kodiak Sciences Inc.

Palo Alto, CA

$105K - $143K/yr

Full-time

Re-posted 28 days ago

Job description

Kodiak Sciences Inc. is a fast-growing, clinical-stage biopharmaceutical company focused on transforming ophthalmology through innovative therapeutics. Our Antibody Biopolymer Conjugate Drug (ABCD) platform integrates protein and peptide engineering & discovery, polymer chemistry, small molecule drug discovery, bioconjugation, and drug delivery technologies to address high-prevalence ophthalmic diseases.
We are seeking a talented Scientist/Senior Scientist to advance peptide therapeutic drug discovery and development programs with a strong emphasis on molecular design, organic synthesis, and analytical characterization.
Key Responsibilities
  • Lead the design, synthesis, and optimization of peptide-based therapeutics, integrating Structure-Activity Relationship (SAR) considerations, developability and conjugation strategies to drive candidate progression.
  • Perform hands-on experimental work including, but not limited to DNA-Encoded Library synthesis, Macrocyclic and Linear Peptide synthesis, polymer conjugation chemistry, purification and analytical evaluation, data interpretation and developability risk assessment.
  • Develop and apply analytical and biophysical methods (e.g., LC-MS, HPLC, NMR, SEC, DLS) to characterize peptides and bioconjugates, including purity, heterogeneity, stability, and aggregation.
  • Collaborate cross-functionally and communicate scientific findings through presentations, reports, and regulatory documentation.
Education / Qualifications
  • Ph.D. in Medicinal Chemistry, Organic Chemistry, Chemical Biology, Biochemistry, or a related field, with either (i) 0–3 years of relevant postdoctoral experience and at least one first-author publication in a high-impact, peer-reviewed journal (preferred), or (ii) 3+ years of relevant industry experience.
  • Experience working with either of the following methodologies, such as Solid Phase Peptide Synthesis (SPPS), DNA-Encoded Library (DEL) synthesis, liquid phase parallel synthesis and/or polymer-based bioconjugates is highly desirable.
  • Strong experience in therapeutic development of peptides, and/or conjugated biologics, experience in analytical characterization is a plus.
  • Proficiency in chromatographic and mass spectrometry-based techniques, with an understanding of developability attributes such as stability, solubility, and manufacturability is a plus.
  • Experience in using software such as PyMol, MOE, Schrödinger, Maestro, DataWarrior, Vortex is a plus.
  • Experience with CD and/or FTIR for peptide secondary structure determination is a plus.
  • Hands-on experience with biochemical assays, including SPR, ELISA, fluorescence-based assays, is a plus.
  • Demonstrated ability to independently drive scientific work in a collaborative, cross-functional environment, with strong problem-solving and communication skills.