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Solubility Jobs (NOW HIRING)

Conduct lab-scale experiments for process development, including reactions, purification, solubility, and process feasibility studies (15%). * Provide support in the design and development of process ...

Geochemist - Senior Level (Hybrid)

Denver, CO · On-site +1

$116K - $161K/yr

... solubility, and water quality. In addition to technical leadership, this position includes mentoring staff, collaborating with clients and regulators, and supporting the continued growth of Barr ...

Geochemist - Senior Level (Hybrid)

Grand Rapids, MI · On-site +1

$109K - $150K/yr

... solubility, and water quality. In addition to technical leadership, this position includes mentoring staff, collaborating with clients and regulators, and supporting the continued growth of Barr ...

Generate and validate dig polygons and ore/waste boundaries for both sulfide mill feed and oxide leach material, ensuring correct routing based on copper grade, mineralization type, solubility ...

Geochemist - Senior Level (Hybrid)

Reno, NV · On-site +1

$113K - $156K/yr

... solubility, and water quality. In addition to technical leadership, this position includes mentoring staff, collaborating with clients and regulators, and supporting the continued growth of Barr ...

Geochemist - Senior Level (Hybrid)

Salt Lake City, UT · On-site +1

$109K - $151K/yr

... solubility, and water quality. In addition to technical leadership, this position includes mentoring staff, collaborating with clients and regulators, and supporting the continued growth of Barr ...

Geochemist - Senior Level (Hybrid)

Ann Arbor, MI · On-site +1

$111K - $153K/yr

... solubility, and water quality. In addition to technical leadership, this position includes mentoring staff, collaborating with clients and regulators, and supporting the continued growth of Barr ...

Geochemist - Senior Level (Hybrid)

Minneapolis, MN · On-site +1

$118K - $163K/yr

... solubility, and water quality. In addition to technical leadership, this position includes mentoring staff, collaborating with clients and regulators, and supporting the continued growth of Barr ...

Geochemist - Senior Level (Hybrid)

Hibbing, MN · On-site +1

$111K - $154K/yr

... solubility, and water quality. In addition to technical leadership, this position includes mentoring staff, collaborating with clients and regulators, and supporting the continued growth of Barr ...

Develop and iterate on coffee bases across multiple SKUs: evaluate flavor profile, solubility, mouthfeel, and ingredient compatibility. * Formulate around functional ingredient constraints with a ...

Senior Geologist

Kearny, AZ · On-site

$140 - $190/hr

Generate and validate dig polygons and ore/waste boundaries for both sulfide mill feed and oxide leach material, ensuring correct routing based on copper grade, mineralization type, solubility ...

Geochemist - Senior Level (Hybrid)

Duluth, MN · On-site +1

$112K - $155K/yr

... solubility, and water quality. In addition to technical leadership, this position includes mentoring staff, collaborating with clients and regulators, and supporting the continued growth of Barr ...

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Solubility information

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$35K

$87.7K

$148K

How much do solubility jobs pay per year?

As of Aug 10, 2026, the average yearly pay for solubility in the United States is $87,733.00, according to ZipRecruiter salary data. Most workers in this role earn between $59,000.00 and $110,000.00 per year, depending on experience, location, and employer.

What are the key skills and qualifications needed to thrive as a solubility scientist, and why are they important?

To thrive as a Solubility Scientist, you need a strong background in chemistry or pharmaceutical sciences, with expertise in analytical techniques and a relevant degree. Familiarity with laboratory instruments such as HPLC, UV-Vis spectrophotometry, and solubility testing equipment, along with knowledge of quality and safety standards, is typically required. Attention to detail, problem-solving abilities, and effective communication are vital soft skills for this role. These competencies ensure accurate experimental outcomes, support drug development or material science research, and facilitate clear reporting of findings.

What does a solubility scientist do?

A solubility scientist studies how substances dissolve in various solvents, determining the conditions and factors that affect solubility. They are often employed in industries such as pharmaceuticals, chemicals, and food science to optimize formulations and ensure product stability. Their work involves conducting experiments, analyzing data, and developing new methods to improve the solubility of compounds. This role is crucial for drug development, as the solubility of a compound can affect its efficacy and delivery. Solubility scientists typically have backgrounds in chemistry, chemical engineering, or related fields.

What are some common challenges faced by solubility scientists when optimizing drug formulations, and how are these typically addressed?

Solubility scientists often encounter challenges such as poor aqueous solubility of drug candidates, which can limit bioavailability and therapeutic effectiveness. To address these, they routinely collaborate with formulation chemists and analytical teams to explore techniques like salt formation, particle size reduction, and the use of solubilizing excipients. Regular communication within cross-functional teams is essential to troubleshoot issues and adapt strategies based on experimental data. Staying updated with emerging technologies and regulatory guidelines also plays a vital role in overcoming these challenges.

What is the difference between Solubility vs Chemist?

AspectSolubilityChemist
Required CredentialsHigh school diploma or equivalent; often a degree in chemistry or related fieldBachelor's degree in chemistry or related field; advanced roles may require a master's or PhD
Work EnvironmentLaboratories, manufacturing plants, research facilitiesLaboratories, research institutions, industry settings
Industry UsageUsed in chemistry, pharmaceuticals, materials science to describe substance behaviorProfessionals conducting chemical research, analysis, and development

Solubility refers to a substance's ability to dissolve in a solvent, a key concept in chemistry and material sciences. A chemist is a professional who studies, analyzes, and develops chemical substances, often applying knowledge of solubility. While solubility is a scientific property, a chemist uses this property in practical applications. Understanding the difference helps clarify that solubility is a concept, whereas a chemist is a role that utilizes such concepts in various industries.

More about Solubility jobs
Infographic showing various Solubility job openings in the United States as of August 2026, with employment types broken down into 31% Full Time, 66% Part Time, 1% Temporary, and 2% Contract. Highlights an 34% Physical, and 66% Remote job distribution, with an average salary of $87,733 per year, or $42.2 per hour.

Pharmaceutical Formulation Chemist

K2 Staffing

Temecula, CA

Contractor

Posted 13 days ago


Job description

Summary

Our client is seeking an experienced Formulation Chemist to support the development of lyophilized injectable vials and oral capsule formulations on a project-based (Statement of Work / Per Diem) basis. This role is ideal for a pharmaceutical formulation expert with hands-on experience developing injectable and oral solid-dose products who can independently lead formulation activities from concept through regulatory readiness.

The successful candidate will have expertise in formulation development, excipient selection, lyophilization, stability studies, GMP documentation, and technical writing while collaborating with Quality, Regulatory, Manufacturing, and Analytical teams to support product commercialization.

Duties & Responsibilities Formulation Development
  • Develop formulations for lyophilized injectable vials and oral capsule products.
  • Design and execute formulation development studies, including excipient selection, buffer optimization, and compatibility assessments.
  • Troubleshoot formulation challenges related to solubility, stability, aggregation, dissolution, and product performance.
  • Support scale-up activities from laboratory development through manufacturing.
Lyophilization & Injectable Products
  • Develop and optimize lyophilization cycles, including freezing, primary drying, and secondary drying.
  • Investigate and resolve reconstitution and product stability issues.
  • Support sterile fill-finish activities, ensuring compatibility with filtration systems and filling equipment.
Oral Solid Dose Development
  • Develop oral capsule formulations, including excipient compatibility and fill-weight uniformity.
  • Evaluate formulation performance and identify opportunities to improve bioavailability where appropriate.
  • Generate technical data packages supporting manufacturing partners.
Stability, Documentation & Regulatory Support
  • Design and execute accelerated and long-term stability studies in accordance with ICH guidelines.
  • Prepare formulation development reports, technical protocols, batch records, and supporting GMP documentation.
  • Collaborate with Quality and Regulatory teams to ensure formulation data supports regulatory compliance, including 503A/503B requirements.
  • Support manufacturing and analytical teams by providing formulation expertise throughout the product lifecycle.
Qualifications & Requirements Required Experience
  • Bachelor's or Master's degree in Chemistry, Pharmaceutical Sciences, Chemical Engineering, or a related scientific discipline (PhD preferred).
  • Minimum 3 years of pharmaceutical formulation experience developing both injectable (lyophilized) and oral solid-dose products.
  • Hands-on experience with lyophilization cycle development and freeze-drying equipment.
  • Experience developing oral capsule formulations, including excipient selection and fill-weight optimization.
  • Strong understanding of formulation challenges, including solubility, stability, aggregation, and excipient compatibility.
Technical Skills
  • Experience designing and executing formulation development studies.
  • Knowledge of GMP documentation, batch records, technical protocols, and formulation reports.
  • Familiarity with ICH stability guidelines and stability protocol development.
  • Understanding of USP <795>, USP <797>, and/or 503A/503B regulatory requirements preferred.
  • Experience supporting sterile fill-finish operations and aseptic processing is highly desirable.
Professional Skills
  • Strong technical writing and documentation skills.
  • Excellent analytical, problem-solving, and troubleshooting abilities.
  • Ability to work independently while collaborating with cross-functional teams.
  • Strong organizational skills with the ability to manage multiple project priorities.
Employment Type: Contract Location: Temecula, CA