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Solubility Jobs (NOW HIRING)

Chemence

Process Engineer

Alpharetta, GA · On-site

Conduct lab-scale experiments for process development, including reactions, purification, solubility, and process feasibility studies (15%). * Provide support in the design and development of process ...

Lancesoft Inc

Lab Technician

Saint Petersburg, FL

$17.50 - $23.25/hr

... of solubility, compatibility samples • Sets up, operates and cleans mixers, laboratory scale encapsulation machine, coating pan and/or other equipment • Prepares laboratory fill mixes • ...

Lancesoft INC

Lab Technician

Saint Petersburg, FL · On-site

$21 - $23/hr

... of solubility, compatibility samples • Sets up, operates and cleans mixers, laboratory scale encapsulation machine, coating pan and/or other equipment • Prepares laboratory fill mixes • ...

LanceSoft

Lab Technician

Saint Petersburg, FL · On-site

$18 - $24/hr

... of solubility, compatibility samples • Sets up, operates and cleans mixers, laboratory scale encapsulation machine, coating pan and/or other equipment • Prepares laboratory fill mixes • ...

Barr

Geochemist - Senior Level (Hybrid)

Reno, NV · On-site +1

... solubility, and water quality. In addition to technical leadership, this position includes mentoring staff, collaborating with clients and regulators, and supporting the continued growth of Barr ...

ASARCO

Senior Geologist

Kearny, NJ · On-site

Generate and validate dig polygons and ore/waste boundaries for both sulfide mill feed and oxide leach material, ensuring correct routing based on copper grade, mineralization type, solubility ...

Barr

Geochemist - Senior Level (Hybrid)

Minneapolis, MN · On-site +1

... solubility, and water quality. In addition to technical leadership, this position includes mentoring staff, collaborating with clients and regulators, and supporting the continued growth of Barr ...

ASARCO LLC

Senior Geologist

Kearny, AZ · On-site

Generate and validate dig polygons and ore/waste boundaries for both sulfide mill feed and oxide leach material, ensuring correct routing based on copper grade, mineralization type, solubility ...

Barr

Geochemist - Senior Level (Hybrid)

Grand Rapids, MI · On-site +1

... solubility, and water quality. In addition to technical leadership, this position includes mentoring staff, collaborating with clients and regulators, and supporting the continued growth of Barr ...

Barr

Geochemist - Senior Level (Hybrid)

Hibbing, MN · On-site +1

... solubility, and water quality. In addition to technical leadership, this position includes mentoring staff, collaborating with clients and regulators, and supporting the continued growth of Barr ...

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All JobsSolubility Jobs

Solubility information

See salary details

$35K

$87.7K

$148K

How much do solubility jobs pay per year?

As of Jun 4, 2026, the average yearly pay for solubility in the United States is $87,733.00, according to ZipRecruiter salary data. Most workers in this role earn between $59,000.00 and $110,000.00 per year, depending on experience, location, and employer.

What are the key skills and qualifications needed to thrive as a Solubility Scientist, and why are they important?

To thrive as a Solubility Scientist, you need a strong background in chemistry or pharmaceutical sciences, with expertise in analytical techniques and a relevant degree. Familiarity with laboratory instruments such as HPLC, UV-Vis spectrophotometry, and solubility testing equipment, along with knowledge of quality and safety standards, is typically required. Attention to detail, problem-solving abilities, and effective communication are vital soft skills for this role. These competencies ensure accurate experimental outcomes, support drug development or material science research, and facilitate clear reporting of findings.

What are some common challenges faced by solubility scientists when optimizing drug formulations, and how are these typically addressed?

Solubility scientists often encounter challenges such as poor aqueous solubility of drug candidates, which can limit bioavailability and therapeutic effectiveness. To address these, they routinely collaborate with formulation chemists and analytical teams to explore techniques like salt formation, particle size reduction, and the use of solubilizing excipients. Regular communication within cross-functional teams is essential to troubleshoot issues and adapt strategies based on experimental data. Staying updated with emerging technologies and regulatory guidelines also plays a vital role in overcoming these challenges.

What does a solubility scientist do?

A solubility scientist studies how substances dissolve in various solvents, determining the conditions and factors that affect solubility. They are often employed in industries such as pharmaceuticals, chemicals, and food science to optimize formulations and ensure product stability. Their work involves conducting experiments, analyzing data, and developing new methods to improve the solubility of compounds. This role is crucial for drug development, as the solubility of a compound can affect its efficacy and delivery. Solubility scientists typically have backgrounds in chemistry, chemical engineering, or related fields.

What is the difference between Solubility vs Chemist?

AspectSolubilityChemist
Required CredentialsHigh school diploma or equivalent; often a degree in chemistry or related fieldBachelor's degree in chemistry or related field; advanced roles may require a master's or PhD
Work EnvironmentLaboratories, manufacturing plants, research facilitiesLaboratories, research institutions, industry settings
Industry UsageUsed in chemistry, pharmaceuticals, materials science to describe substance behaviorProfessionals conducting chemical research, analysis, and development

Solubility refers to a substance's ability to dissolve in a solvent, a key concept in chemistry and material sciences. A chemist is a professional who studies, analyzes, and develops chemical substances, often applying knowledge of solubility. While solubility is a scientific property, a chemist uses this property in practical applications. Understanding the difference helps clarify that solubility is a concept, whereas a chemist is a role that utilizes such concepts in various industries.

More about Solubility jobs
What job categories do people searching Solubility jobs look for? The top searched job categories for Solubility jobs are:
Solubility jobs near you
Infographic showing various Solubility job openings in the United States as of May 2026, with employment types broken down into 33% Full Time, 66% Part Time, and 1% Contract. Highlights an 30% Physical, 1% Hybrid, and 69% Remote job distribution, with an average salary of $87,733 per year, or $42.2 per hour.

Principal Scientist - Solubility Enhancement Technologies

Ardena

Somerset, NJ • On-site

Full-time

Medical, PTO

This job post has expired 1 day ago. Applications are no longer accepted.

Job description

About Ardena Ardena is a global Contract Development and Manufacturing Organization (CDMO) and Contract Research Organization (CRO) specializing in precision medicine development. Ardena supports pharmaceutical and biotechnology companies in bringing innovative, complex molecules from discovery to market. The Ardena Group operates from five sites across Europe and the United States, employing more than 750 professionals. Ardena European sites are located in Oss and Assen (the Netherlands), Ghent (Belgium), and Pamplona (Spain). Ardena US facility is based in Somerset, New Jersey. For the Ardena Business Unit based in Somerset (US), we are looking for a [Job Title] Ardena provides integrated services spanning drug substance development, drug product formulation, GMP manufacturing, bioanalytical services, clinical logistics, fill and finish, and CMC regulatory support. Job Overview Position: Principal Scientist - Solubility Enhancement Technologies Department: Product Development Location: Somerset (US) Role Description The Principal Scientist - Solubility Enhancement Technologies leads formulation and process development for oral solid dosage forms, with a primary focus on hot melt extrusion (HME), spray drying, and amorphous solid dispersion (ASD) technologies. Working across the full development continuum from preclinical through commercial, this role serves as a key technical contributor and scientific expert within Ardena's CDMO environment. The successful candidate will bring deep expertise across multiple solubility enhancement platforms, the ability to plan and organise their own work effectively, a client-service orientation, and a commitment to quality and regulatory compliance. Key Responsibilities
  • Lead the development of amorphous solid dispersions (ASD) and solubility-enhanced oral dosage forms using hot melt extrusion (HME) and spray drying as the primary technology platforms, from preclinical concept through clinical and commercial formulation.
  • Apply expertise in solid oral dosage form development - encompassing formulation design, process development, scale-up, and technology transfer - across preclinical, clinical, and commercial stages.
  • Define pilot plant batch manufacturing requirements, oversee study execution, and provide technical consultation during clinical and commercial batch manufacture.
  • Collaborate with the preformulation team to characterize materials using DSC, TGA, XRPD, SEM, and hot-stage microscopy; interpret data and apply findings to formulation strategy.
  • Author high-quality GDP-compliant technical documents including development reports, technical specifications, project risk assessments, and regulatory CMC submissions in accordance with applicable guidance and site SOPs.
  • Design and interpret experiments using statistical analysis, design of experiments (DoE), and data visualization tools to support robust development decisions.
  • Plan and organize assigned work across multiple concurrent projects, prioritizing effectively to meet scientific, regulatory, and client timelines.
  • Develop formulation strategies and lifecycle plans that align with regulatory requirements and client objectives.
  • Proactively acquire and apply new scientific principles and technologies with minimal direction.
  • Ensure compliance with Health, Safety, and Environmental requirements; maintain current training records for all required procedures.
  • Contribute to the training and mentoring of junior R&D personnel as required.
  • Communicate scientific findings clearly and persuasively in written and verbal formats to both internal teams and external clients.
  • Manage difficult client discussions constructively, guiding conversations toward acceptable resolutions.
  • Enhance Ardena's scientific visibility through publications, webinars, conference presentations, and symposia.
  • Support departmental goals by delivering high-quality technical work and maintaining strong client relationships.
  • Identify and recommend emerging technologies with potential application to Ardena's solubility enhancement service offerings.
Business Development
  • Support Business Development activities as needed, including client calls, new customer meetings, and occasional travel to help secure new business.
Regulatory & Scientific Output
  • Understand the structure and content requirements of CMC regulatory filing packages; author and review formulation and analytical sections of regulatory submissions.
  • Publish or present research findings internally and externally to advance scientific knowledge and Ardena's profile.
Position Requirements A PhD in Chemistry, Pharmaceutics, Pharmaceutical Sciences, Chemical Engineering, or a closely related discipline is preferred. Candidates holding an MS or BS in a relevant field will be considered with the requisite years of experience outlined below. Experience
  • PhD: minimum 5 years | MS: minimum 10 years | BS: minimum 12 years of experience in formulation development of prescription oral solid dosage forms.
  • At least 3 years of hands-on experience in ASD development is required, with demonstrated proficiency in hot melt extrusion (HME), spray drying, or both. Experience with both platforms is strongly preferred.
  • Experience with twin-screw melt granulation, twin-screw wet granulation, and/or process analytical technology (PAT) is preferred.
  • Hands-on proficiency with DSC, TGA, XRPD, and hot-stage microscopy is preferred.
Knowledge & Skills A strong foundation in scientific principles relevant to pharmaceutical development is required, including organic chemistry, polymer chemistry, solid-state chemistry, and pharmaceutics. Familiarity with common pharmaceutical processing techniques (tablets, capsules, modified-release dosage forms) and proficiency in Microsoft Office (Word, Excel, PowerPoint) are expected. Hands-on expertise in the following solubility enhancement technologies is required or strongly preferred:
  • ASD by hot melt extrusion (HME) - required
  • ASD by spray drying - required
  • Nanosuspension technologies - preferred
What Ardena Offers Ardena is a science-driven and people-focused employer. Working at Ardena means contributing to pharmaceutical projects that support the availability, safety, and quality of medicines for patients worldwide. Ardena offers an international working environment where employees are encouraged to develop their expertise, take ownership, and grow their careers across functions and locations. Benefits and perks at Ardena include: • Competitive salary and tailored benefits package (adjusted per role and location) • Flexible working arrangements and paid annual leave (where applicable, depending on role and site) • International and collaborative work environment across European and US sites • Access to professional development and training programs • Meaningful work on pharmaceutical development projects that advance patient health • A values-driven culture guided by Ardena's CARE principles: Communicative, Accountable, Reliable, and Excellent How to Apply Ready to advance your career in pharmaceutical development? Apply now through the Ardena Careers website at careers.ardena.com. Department Research & Development Locations Somerset (New Jersey, US) Remote status Hybrid

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