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Single Molecule Biophysics Jobs (NOW HIRING)

$55 - $65/hr

The postdoctoral scholar will develop and apply advanced biophysical, bioengineering, and cell biology approaches, including single-molecule force spectroscopy, single-molecule fluorescence imaging ...

$48K - $65K/yr

We leverage single-molecule super-resolution imaging, advanced lattice light sheet microscopy and other state of the art biophysical approaches to study molecular mechanisms of transcription, genome ...

... single-molecule biophysics of the nucleosome, RNA polymerase II, and chromatin remodelers. The position requires a Ph.D. in an area of physical or biological sciences or equivalent doctorate in an ...

... Biophysics or Biochemistry. Previous experience of working with purified proteins and/or single-molecule microscopy is beneficial but not required. To be considered, please submit your CV ...

... Biophysics or Biochemistry. Previous experience of working with purified proteins and/or single-molecule microscopy is beneficial but not required. To be considered, please submit your CV ...

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Single Molecule Biophysics information

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How much do single molecule biophysics jobs pay per hour?

As of Sep 5, 2026, the average hourly pay for single molecule biophysics in the United States is $21.30, according to ZipRecruiter salary data. Most workers in this role earn between $14.42 and $25.96 per hour, depending on experience, location, and employer.

What is single molecule biophysics?

Single molecule biophysics is a field of science that studies the physical properties and behaviors of individual biological molecules, such as proteins, DNA, and RNA. Unlike traditional biophysics that examines large populations of molecules, single molecule approaches provide detailed insights into molecular mechanisms, dynamics, and interactions. Techniques like optical tweezers, atomic force microscopy, and single-molecule fluorescence are commonly used. This research is important for understanding fundamental biological processes and can lead to advances in medicine and biotechnology.

What are the key skills and qualifications needed to thrive as a single molecule biophysicist?

To thrive as a Single Molecule Biophysicist, you need a strong background in physics, chemistry, and molecular biology, usually supported by an advanced degree (PhD) in biophysics or a related field. Expertise in technical tools such as atomic force microscopy (AFM), optical tweezers, single-molecule fluorescence microscopy, and data analysis software is typically required. Strong analytical thinking, attention to detail, and collaborative communication are essential soft skills in this interdisciplinary field. These skills and qualifications enable accurate experimental design and interpretation, driving innovation and discovery at the molecular level.

What are some common challenges faced by professionals working in single molecule biophysics research?

Professionals in single molecule biophysics often encounter challenges related to the complexity and sensitivity of experimental setups, such as maintaining equipment calibration and minimizing noise that can obscure single-molecule signals. Collaborating closely with interdisciplinary teams—often including physicists, chemists, and biologists—is essential to design experiments, interpret data, and troubleshoot technical issues. Additionally, staying up to date with rapidly evolving technologies and analytical methods is key for success, making continuous learning a significant part of the role.

What is the difference between Single Molecule Biophysics vs Molecular Biophysics?

AspectSingle Molecule BiophysicsMolecular Biophysics
Required CredentialsPh.D. in Biophysics, Physics, or related fieldPh.D. in Biophysics, Biochemistry, or related field
Work EnvironmentLaboratories focusing on single-molecule techniques, microscopy, and spectroscopyLaboratories studying molecular interactions, structural biology, and biophysical mechanisms
Employer & Industry UsageResearch institutions, universities, biotech companies
Common Search & ComparisonYes

Single Molecule Biophysics focuses on studying individual molecules using specialized techniques like fluorescence microscopy, while Molecular Biophysics examines the physical principles governing molecular interactions and structures. Both fields require advanced degrees and often overlap in research settings, but they differ in their specific methods and focus areas.

More about Single Molecule Biophysics jobs
Infographic showing various Single Molecule Biophysics job openings in the United States as of August 2026, with employment types broken down into 1% Locum Tenens, 1% As Needed, 79% Full Time, 16% Part Time, 2% Contract, and 1% Nights. Highlights an 91% Physical, 2% Hybrid, and 7% Remote job distribution, with an average salary of $44,307 per year, or $21.3 per hour.

Postdoctoral Associate - Cell and Systems Biology

University of Miami

Miami, FL • On-site

$55 - $65/hr

Other

Medical, Dental

Re-posted 15 days ago


University Of Miami rating

7.7

Company rating: 7.7 out of 10

Based on 52 frontline employees who took The Breakroom Quiz

265th of 630 rated colleges and universities


Job description

## Postdoctoral Associate - Cell and Systems BiologyApplyremote type: On-Sitelocations: Miami, FLtime type: Full timeposted on: Posted Todayjob requisition id: R100099728**Current Employees:**If you are a current Staff, Faculty or Temporary employee at the University of Miami, please click here to log in to Workday to use the internal application process. To learn how to apply for a faculty or staff position, please review this tip sheet.**CORE JOB SUMMARY** The Postdoctoral Associate performs scientific research and studies under the supervision of managing staff. Moreover, the Postdoctoral Associate promotes institutional recognition through literal contributions to the scientific community. **CORE JOB FUNCTIONS** 1. Conducts research on specific areas of study as assigned. 2. Prepares research reports and technical papers for publishing. 3. Investigates the feasibility of applying a wide variety of scientific principles and theories. 4. Maintains substantial knowledge of state-of-the-art principles and theories. 5. Develops advanced analytical models and systems and provides solutions and analyses to support strategic and tactical decisions. 6. Adheres to University and unit-level policies and procedures and safeguards University assets. This list of duties and responsibilities is not intended to be all-inclusive and may be expanded to include other duties or responsibilities as necessary. **CORE QUALIFICATIONS** Education: Doctorate degree in relevant field required Experience: No previous experience required Certification and Licensing: Refer to department description for applicable certification requirements Knowledge, Skills and Abilities:* Learning Agility: Ability to learn new procedures, technologies, and protocols, and adapt to changing priorities and work demands.* Teamwork: Ability to work collaboratively with others and contribute to a team environment.* Technical Proficiency: Skilled in using office software, technology, and relevant computer applications.* Communication: Strong and clear written and verbal communication skills for interacting with colleagues and stakeholders.**DEPARTMENT ADDENDUM****Department Specific Functions**We are seeking a highly motivated scientist to join our group as a Postdoctoral Scholar. Our laboratory develops and applies multidisciplinary approaches, including single-molecule force spectroscopy, single-molecule fluorescence imaging, stem cell-derived organoids, gene editing, and microfluidics, to address fundamental biological questions and unmet medical needs.The successful candidate will investigate how biomolecules and cells sense and respond to changes in their mechanical and biochemical microenvironment. The postdoctoral scholar will develop and apply advanced biophysical, bioengineering, and cell biology approaches, including single-molecule force spectroscopy, single-molecule fluorescence imaging, stem cell-derived organoid models, gene editing, and microfluidic technologies. Research projects will focus on understanding molecular and cellular mechanisms that regulate cardiovascular, renal, and respiratory physiology and disease. The candidate is expected to lead research projects, publish findings in high-impact journals, present at scientific conferences, and contribute to the mentoring of junior trainees in the laboratory.**Department Specific Qualifications****Education:**Ph.D.**Experience:**Applicants must have a Ph.D. (or foreign equivalent) in Biophysics, (Stem) Cell Biology, Molecular Biology, Bioengineering, Physics, or a related field. Candidates should have no more than two years of prior postdoctoral research experience.**Knowledge, Skills and Attitudes:**Preferred qualifications include research experience in one or more of the following areas: single-molecule biophysics, stem cells and organoids, microfluidics, fluorescence microscopy, or scientific programming for data acquisition, instrument control, and image analysis using LabVIEW, MATLAB, or related platforms.Candidates must have at least one first-author research article accepted for publication in a peer-reviewed journal.**PHYSICAL REQUIREMENTS/ WORKING ENVIRONMENT***The following sections capture the physical demands and working environment that are required for this job. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions.***Working Conditions****Environmental Dimension****Never****Occasionally****Frequently****Constantly**Conditions of extreme heat or extreme coldxWet/Humid conditionsxFumes/Dust/Dirt/SmokexConfined areasxHigh placesxEquipment in motionxHigh noise levelsxEnvironmental hazardsxExposure to TBxExposure to Blood-borne Pathogens xExposure to Radiant EnergyxOutdoor/Exposed areasx**Equipment Used****Equipment Used****Never****Occasionally****Frequently****Constantly****Vehicle Type**Operate vehicles (Select Vehicle)xUse hand tools xUse power tools x**Physical Requirements****Physical Dimension****Never****Occasionally****Frequently****Constantly****Weight**SittingxStanding xWalking xStooping/Climbing xCarrying xKneeling xCrouchingxBendingxCrawlingxReachingxHandlingx**Sensory Requirements****Sensory Dimension****Never****Occasionally****Frequently****Constantly****Vision Type**VisionxDepth Perception xColor Vision xPeripheral xConcentration xUse of keyboard or touchscreenxTalkingxFeeling xSmelling x**The above statements are intended to describe the general nature and primary responsibilities of this job classification. Specific duties and tasks may vary based upon departmental needs. Other duties may be assigned to the above consistent with the knowledge, skills, and abilities required for the job. This is a job profile description and not all duties may be assigned to a specific position in each individual department.**The University of Miami offers competitive salaries and a comprehensive benefits package including medical, dental, tuition remission and more.UHealth-University of Miami Health System, South Florida's only university-based health system, provides leading-edge patient care powered by the ground breaking research and medical education at the Miller School of Medicine. As an academic medical center, we are proud to serve South Florida, Latin America and the Caribbean. Our physicians represent more than 100 specialties and sub-specialties, and have more than one million patient encounters each year. Our tradition of excellence has earned worldwide recognition for outstanding teaching, research and patient care. We're the challenge you've been looking for.The University of Miami is an Equal Opportunity Employer. Applicants and employees are protected from discrimination based on certain categories protected by Federal law.**Job Status:**Full time**Employee Type:**Staff #J-18808-Ljbffr

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About University of Miami

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The University of Miami, located in the beautiful Coral Gables, Florida, is a comprehensive, private research institution in the United States. Operating within the higher education industry, the institution offers a multitude of degree programs spanning over 180 majors and program through its 12 colleges. The University was founded in 1925 with the mission to disseminate knowledge, transform lives, and change the world - a mission it has held faithfully to this day. Notably, the University of Miami has gained global recognition for its commitment to research and innovation, with over $324 million in research and sponsored project funding awarded annually.

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Colleges, universities, and professional schools

Company size

10,000+ Employees

Headquarters location

Coral Gables, FL, US

Year founded

1925