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Simoa Jobs (NOW HIRING)

QUANTERIX CORP

Senior Scientist

Billerica, MA · On-site

$125K - $145K/yr

Senior Scientist, Simoa Technology Billerica, MA Quanterix is a global leader in ultra-sensitive biomarker detection, enabling breakthroughs in disease research, diagnostics, and drug development.

New

Quanterix

Senior Scientist

Billerica, MA

$125K - $145K/yr

Senior Scientist, Simoa TechnologyBillerica, MA Quanterix is a global leader in ultra-sensitive biomarker detection, enabling breakthroughs in disease research, diagnostics, and drug development. Its ...

Quanterix

Sr. Director, Assay Development

Billerica, MA

$225K - $265K/yr

Its proprietary Simoa ® technology delivers industry-leading sensitivity, allowing researchers to detect and quantify biomarkers in blood and other fluids at concentrations far below traditional ...

Ampcus Inc

Lab Technician

San Diego, CA · On-site

$20.25 - $26.75/hr

They also perform immunoassays on different platforms including plate ELISA, Simoa, Meso Scale, NuLisa and others. The position has a scientific focus that consists of developing biochemical ...

Lancesoft INC

Scientist

San Diego, CA · On-site

$35 - $38/hr

They also perform immunoassays on different platforms including plate ELISA, Simoa, Meso Scale, NuLisa and others. The position has a scientific focus that consists of developing biochemical ...

Massgeneralbrigham

Research Lab Technician I

Boston, MA

$21 - $29.01/hr

The laboratory develops and applies ultrasensitive protein detection technologies, including single molecule array (Simoa) and Molecular On-bead Signal Amplification for Individual Counting (MOSAIC ...

Quanterix

Customer Care Specialist - West Coast

Billerica, MA · On-site

$18 - $24/hr

Its proprietary Simoa technology delivers industry-leading sensitivity, allowing researchers to detect and quantify biomarkers in blood and other fluids at concentrations far below traditional limits.

Mass General Brigham

Research Lab Technician I

Boston, MA · On-site

$21 - $29.01/hr

The laboratory develops and applies ultrasensitive protein detection technologies, including single molecule array (Simoa) and Molecular On-bead Signal Amplification for Individual Counting (MOSAIC ...

Frontage Laboratories

Senior Scientist

Exton, PA · On-site

$88K - $120K/yr

Utilizing various types of instrument including MSD, ELISA, SIMOA etc. Requirement: * M.S level with 3+ years of experience or Ph.D. level Salary and Benefits: Frontage Laboratories offers a ...

UPMC Senior Communities

Research Specialist

Pittsburgh, PA · On-site

$20 - $30.55/hr

Operate various instruments, including SIMOA, NULISA, Lumipulse, etc. * Perform regular maintenance on laboratory equipment. * Maintain thorough and organized electronic records of research results ...

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Simoa information

What is a Simoa analyst or technician?

Simoa analysts or technicians are professionals who operate and manage Simoa (Single Molecule Array) technology, a highly sensitive platform used for detecting and quantifying low-abundance biomarkers in biological samples. Their primary responsibilities include preparing samples, running assays on Simoa instruments, interpreting results, and maintaining laboratory equipment. These specialists often work in clinical or research labs, supporting studies in areas such as neurology, oncology, and infectious diseases. They must be familiar with laboratory protocols, data analysis, and quality control procedures to ensure accurate and reliable results.

What are the key skills and qualifications needed to thrive as a Simoa research scientist, and why are they important?

To thrive as a Simoa Research Scientist, you need a strong background in biochemistry, molecular biology, or immunology, often supported by a graduate degree in a related field. Experience with Simoa analyzers, ELISA platforms, and data analysis software such as SoftMax Pro or Prism is typically required. Attention to detail, problem-solving abilities, and effective communication are valuable soft skills for designing experiments and collaborating with cross-functional teams. These skills ensure accurate biomarker quantification, robust experimental results, and successful contributions in a cutting-edge diagnostics environment.

What are some common challenges faced by Simoa assay technicians, and how can they be addressed?

Simoa assay technicians often encounter challenges such as maintaining assay precision, troubleshooting instrument errors, and handling sensitive biological samples. To address these, technicians regularly calibrate and maintain equipment, strictly follow standard operating procedures, and collaborate closely with scientists and lab managers. Staying updated on best practices and participating in ongoing training can also help mitigate common issues and ensure reliable results.
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Infographic showing various Simoa job openings in the United States as of August 2026, with employment types broken down into 84% Full Time, and 16% Contract. Highlights an 97% Physical, and 3% Hybrid job distribution.

Senior Scientist

Billerica, MA • On-site

QUANTERIX CORP
Biotechnology Research and Development • 201 - 500 employees
Learn more about QUANTERIX CORPexternal

$125K - $145K/yr

Full-time

Medical, Dental, Vision, Retirement, PTO

Posted 3 days ago

New

Job description

Senior Scientist, Simoa Technology
Billerica, MA
Quanterix is a global leader in ultra-sensitive biomarker detection, enabling breakthroughs in disease research, diagnostics, and drug development. Its vision is to lead the next era of precision biomarker science to power earlier detection, better decisions, and improved human health. Its mission is to make biology measurable at its most fundamental level, delivering earlier insight when it matters most. Across discovery to clinical applications, Quanterix empowers scientists and healthcare providers to improve patients' lives through detection and understanding of disease. Its proprietary Simoa® technology delivers industry-leading sensitivity, allowing researchers to detect and quantify biomarkers in blood and other fluids at concentrations far below traditional limits. With more than 3,400 peer-reviewed publications, Quanterix has been a trusted partner to the scientific community for nearly two decades. In 2025, Quanterix acquired Akoya Biosciences, The Spatial Biology Company®, adding multiplexed tissue imaging with single-cell resolution to its portfolio. Together, the combined company offers a uniquely integrated platform that connects biology across blood and tissue-advancing precision medicine from discovery to diagnostics.
ROLE SUMMARY:
We are seeking a talented and highly motivated Senior Scientist to join our Technology group. In this role, the Senior Scientist will work within the Technology group and with cross-functional teams, as well as third-party partners and collaborators, to develop technologies that will form the basis of our next generation of Simoa biomarker measurement systems. This role will involve the development and characterization of new Simoa assay and hardware capabilities during feasibility work. This person will provide a link between the Technology team and the development teams, including engineering and assay teams, to transfer new technologies from feasibility into full development. The Senior Scientist will be expected to communicate their work through presentations at conferences and in peer-reviewed publications.
WHAT YOU'LL DO:
  • Feasibility research to enable new Simoa technologies
  • Evaluation of assay performance of new Simoa technologies
  • Collaboration with engineers and scientists in the Technology group on hardware development and image analysis
  • Interacting with engineering and assay development groups to transfer new Simoa technologies from feasibility to full development
BASIC QUALIFICATIONS:
• PhD in biological or physical sciences.
• Strong background in technology development pertaining to novel assay and system development.
• Strong background in experimental design and communication of scientific results.
PREFERRED QUALIFICATIONS:
• More than 3 years of experience in biomedical research or the biotech/life sciences industry.
• Industrial experience in assay and instrumentation development.
• Proven track record of developing technologies at the interface of assays and instrumentation.
• Ability to develop a deep understanding of technological impact on assay data, including image analysis and instrumentation process steps.
• Experience with protein and surface conjugation methods.
• Excellent quantitative analytical skills, including the ability to synthesize complex data sets and prepare summative reports.
• Proven ability to collaborate in a multi-disciplinary environment.
• Experience in the development and testing of complex biomedical products and a strong track record of publication.
EXPECTATIONS, COMPETENCIES, SKILLS & ABILITIES:
• Workplace location: Billerica, MA.
• Travel: As required by business needs.
• Ability to work effectively with cross-functional teams, third-party partners, and collaborators.
• Demonstrated capability to design, execute, troubleshoot, and interpret complex experiments that advance novel assay, reagent, imaging, and instrumentation workflows.
• Strong technical judgment and problem-solving skills, with the ability to identify root causes, evaluate tradeoffs, and recommend practical solutions in feasibility and early development settings.
• Ability to translate scientific concepts and feasibility data into clear technical requirements, development plans, and decision-ready recommendations for cross-functional stakeholders.
• Effective communication skills, including the ability to present complex scientific and technical information to internal teams, external collaborators, and scientific audiences.
• Continuous improvement and growth mindset, with a focus on rigorous documentation, reproducibility, data quality, and scalable processes that support transition from research feasibility to product development.
• Adaptability to changing priorities, technical challenges, and evolving business needs, with the ability to remain flexible and productive in a fast-paced development environment.
• Collaborative working style and willingness to help others, contributing expertise, feedback, and support to strengthen team outcomes and shared objectives.
WHY YOU'LL LIKE WORKING WITH US:
Our Technology:
From discovery to diagnostics, Quanterix's ultrasensitive biomarker detection is fueling breakthroughs only made possible through its unparalleled sensitivity and flexibility. Simoa® technology has delivered the gold standard for earlier biomarker detection in blood, serum or plasma, with the ability to quantify proteins that are far lower than the Level of Quantification (LoQ). Our industry-leading precision instruments, digital immunoassay technology and CLIA-certified Accelerator laboratory have supported research that advances disease understanding and management in neurology, oncology, immunology, cardiology, and infectious disease.
Akoya Biosciences, a Quanterix company, is The Spatial Biology Company®-bringing tissue context to life through high-resolution, single-cell imaging. Akoya's spatial phenotyping platforms help researchers visualize and measure how cells organize and interact within tissue to influence disease progression and therapeutic response. From discovery through clinical research, Akoya offers a full continuum of solutions, including PhenoCycler®, PhenoImager® Fusion and HT, and PhenoCode™ Panels. As part of Quanterix, Akoya complements a leading portfolio of ultra-sensitive biomarker detection technologies, together enabling a more complete view of biology and disease across both tissue and blood.
Our Commitment to Employees:
At Quanterix, our values are based on: Team, Innovation, Customer and Owner.
Team: Challenge assumptions, not the person. Respect diversity of thought and hold ourselves to lofty standards.
Innovation: Stay curious, experiment, create and change.
Customer: Prioritize and celebrate these pioneers by doing our best to deliver on commitments.
Owner: Act with high integrity and in the best interest of Quanterix. Take measured risks and learn from their success and failures.
We reward and recognize our employees by offering competitive compensation and a 401k plan with employer match, as well as competitive health, dental, and vision benefits for employees and their dependents. We also offer an unlimited vacation policy to all exempt employees, and a generous PTO policy for non-exempt employees. All employees are eligible for equity, employee stock purchase plan, a performance bonus, and 1:1 financial counseling/planning. We also offer Tuition Assistance. We have a free, state-of-the-art onsite fitness center for all employees. To keep you fueled up, we provide onsite employees free snacks and drinks every day!
Pay Range: $125,000 - $145,000 per year

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