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Simoa Jobs in California (NOW HIRING)

Simoa information

What are some common challenges faced by Simoa assay technicians, and how can they be addressed?

Simoa assay technicians often encounter challenges such as maintaining assay precision, troubleshooting instrument errors, and handling sensitive biological samples. To address these, technicians regularly calibrate and maintain equipment, strictly follow standard operating procedures, and collaborate closely with scientists and lab managers. Staying updated on best practices and participating in ongoing training can also help mitigate common issues and ensure reliable results.

What are the key skills and qualifications needed to thrive as a Simoa research scientist, and why are they important?

To thrive as a Simoa Research Scientist, you need a strong background in biochemistry, molecular biology, or immunology, often supported by a graduate degree in a related field. Experience with Simoa analyzers, ELISA platforms, and data analysis software such as SoftMax Pro or Prism is typically required. Attention to detail, problem-solving abilities, and effective communication are valuable soft skills for designing experiments and collaborating with cross-functional teams. These skills ensure accurate biomarker quantification, robust experimental results, and successful contributions in a cutting-edge diagnostics environment.

What is a Simoa analyst or technician?

Simoa analysts or technicians are professionals who operate and manage Simoa (Single Molecule Array) technology, a highly sensitive platform used for detecting and quantifying low-abundance biomarkers in biological samples. Their primary responsibilities include preparing samples, running assays on Simoa instruments, interpreting results, and maintaining laboratory equipment. These specialists often work in clinical or research labs, supporting studies in areas such as neurology, oncology, and infectious diseases. They must be familiar with laboratory protocols, data analysis, and quality control procedures to ensure accurate and reliable results.
Infographic showing various Simoa job openings in California as of June 2026, with employment types broken down into 100% Full Time. Highlights an 100% In-person job distribution.

Scientist I - Technology Access Program

Alamar Biosciences

Fremont, CA • On-site

Other

Posted 6 days ago


Job description

We seek a highly motivated Scientist to join a dynamic team of professionals in the Technology Access team to support our company mission. In this role, you will work cross-functionally across multiple teams including R&D, Sales and Marketing to design, execute and deliver NULISA immunoassay projects as part of the Technology Access Program. An ideal candidate will have a background in immunology, neuroscience, or proteomics and bring hands-on experience in immunoassay development. The ability to manage complex projects in a fast-paced, collaborative environment is highly preferred.

Primary Responsibilities

  • Design, conduct, and analyze NULISA immunoassay experiments to assess various biomarkers across diverse biological matrices.
  • Design and optimize assay parameters including sensitivity, specificity, detectability, and precision to execute and deliver NULISA immunoassay projects.
  • Troubleshoot technical challenges via root-cause analysis and implement corrective strategies.
  • Collaborate closely with cross-functional teams and external stakeholders to ensure the timely and accurate completion of deliverables.

Requirements

  • Ph.D. in Biochemistry, Molecular Biology, or a related discipline; M.S. with 3+ years of experience will also be considered or BA/BS with 5+ years of experience
  • Hands-on experience in executing and optimizing immunoassays such as ELISA. Experience with high-sensitivity platforms (Simoa, MSD, or Luminex) is a plus but not required.
  • Familiarity with molecular biology methods (e.g., qPCR, ddPCR).
  • Strong problem-solving and analytical skills with attention to detail in experimental execution.
  • Ability to manage time effectively, work collaboratively, and adapt in a fast-paced environment.
  • Strong communication skills, including data presentation and technical documentation.
  • Knowledge of biomarker research, assay validation, or clinical sample testing is desirable.

The base salary range for this full-time position is $120,000 - $140,000 + bonus + equity + benefits. Our salary ranges are determined by work location, job-related skills, experience, and relevant education or training. The ranges displayed on each job posting reflect the minimum and maximum target for new hire salaries but are subject to change if the leveling of the role is adjusted. Your recruiter can share more about the specific salary range during the hiring process.