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Senior Statistical Analyst Jobs (NOW HIRING)

... of senior statistical analysts. This position will also collaborate with internal and external stakeholders, maintain, modify, and develop data-entry interfaces for surveys and monthly reports ...

As a Senior Statistical Programmer you will be dedicated to one of our global pharmaceutical ... Performing data manipulation, analysis and reporting of clinical trial data, both safety and ...

Senior Statistical Programmer/Analyst Consultant (Cardiovascular, Renal) United States Are you interested in working directly for a single sponsor while having the security and additional career ...

Senior Statistical Programmer/Analyst Consultant-(Oncology)Remote in US United States Are you interested in working directly for a single sponsor while having the security and additional career ...

Senior Statistical Programmer/Analyst Consultant - (remote in US) United States Are you interested in working directly for a single sponsor while having the security and additional career ...

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Phoenix, AZ ยท On-site

$60K/yr

... of senior statistical analysts. This position will also collaborate with internal and external stakeholders, maintain, modify, and develop data-entry interfaces for surveys and monthly reports ...

What You'll Do You will lead statistical genetics analyses of primarily population-scale genomics data to inform decisions about new business opportunities and advance internal development programs.

Senior Statistician

$89K - $109K/yr

The Senior Statistician MS performs high-level client statistical consulting and/or leads teams ... Perform Statistical Analysis in support of Phase I-V clinical trials, ISS, ISE, Registries ...

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How much do senior statistical analyst jobs pay per year?

As of Sep 12, 2026, the average yearly pay for senior statistical analyst in the United States is $99,008.00, according to ZipRecruiter salary data. Most workers in this role earn between $87,000.00 and $107,000.00 per year, depending on experience, location, and employer.

What is a senior statistical analyst?

Senior Statistical Analysts are experienced professionals who use advanced statistical methods to collect, analyze, and interpret complex data sets. They often design experiments, develop predictive models, and provide data-driven insights to support business decision-making. In addition to technical expertise, they may oversee junior analysts, collaborate with other departments, and present findings to stakeholders. Their work helps organizations understand trends, measure performance, and identify opportunities or risks.

How does a senior statistical analyst typically collaborate with cross-functional teams on large projects?

Senior Statistical Analysts often work closely with professionals from departments such as data engineering, product management, and business analytics. They translate complex statistical findings into actionable insights, ensuring that technical results are accessible to non-technical stakeholders. Collaboration may involve regular meetings, joint project planning sessions, and iterative feedback loops to refine analyses based on shifting business priorities. This collaborative environment not only enhances project outcomes but also provides opportunities for professional growth through exposure to diverse perspectives and expertise.

What are the key skills and qualifications needed to thrive as a senior statistical analyst, and why are they important?

To thrive as a Senior Statistical Analyst, you need advanced knowledge of statistical theory, data analysis, and a relevant degree in statistics, mathematics, or a related field. Expertise with statistical software such as SAS, R, Python, and experience with data visualization tools are commonly required, along with certifications like SAS Certified Advanced Analytics Professional. Strong problem-solving abilities, attention to detail, and effective communication skills help you translate complex data into actionable insights. These skills ensure accurate analysis, informed decision-making, and clear communication of findings to stakeholders.
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Infographic showing various Senior Statistical Analyst job openings in the United States as of September 2026, with employment types broken down into 1% Internship, 88% Full Time, 6% Part Time, 1% Temporary, and 4% Contract. Highlights an 80% Physical, 7% Hybrid, and 13% Remote job distribution, with an average salary of $99,008 per year, or $47.6 per hour.

Senior Statistical Programmer

Boston, MA โ€ข On-site

Rhythm Pharmaceuticals
Biotechnology Research and Developmentย โ€ขย 51 - 200 employees

Full-time

Posted 11 days ago


Key responsibilities

  • Lead or support statistical programming activities for assigned clinical studies, including development, validation, and quality control of analysis datasets, tables, listings, and figures.

  • Partner closely with Biostatistics, Data Management, Clinical Development, Medical Writing, Regulatory, and external vendors to deliver high-quality results on time.

  • Develop, review, and maintain ADaM specifications, TLF shells, programming documentation, reusable macros, and study-level programming standards.


Job description

Company Overview
Rhythm is a global, commercial-stage biopharmaceutical company committed to transforming the lives of patients living with rare neuroendocrine diseases. We develop medicines for previously untreatable or undertreated diseases. We recognize the courage it takes for patients and their caregivers to begin their journey of advocacy to find the answers they need. Their courage inspires us to challenge convention, ask bold questions and seek answers for them. Every day, we strive for excellence through our willingness to adapt, learn, and our tenacity to overcome barriers, together.
Opportunity Overview
Rhythm is seeking a Senior Statistical Programmer to join our Biostatistics and Statistical Programming team. This role will provide statistical programming hands-on support across clinical studies, regulatory submissions, and cross-functional development activities. The successful candidate will be responsible for delivering high-quality, compliant analysis datasets, tables, listings, and figures; contributing to study-level and integrated submission deliverables; and partnering closely with Biostatistics, Data Management, Clinical Development, Medical Writing, Regulatory, and external vendors. Depending on level, the role may also include broader responsibility for study oversight, process improvement, standards development, vendor oversight, and mentoring programmers. The level will be determined based on the candidate’s experience, technical depth, and leadership capabilities.
Responsibilities and Duties
  • Lead or support statistical programming activities for assigned clinical studies, including development, validation, and quality control of analysis datasets, tables, listings, and figures for study reports, regulatory submissions, and internal decision-making.
  • Serve as a study lead programmer or programming representative, partnering closely with Biostatistics, Data Management, Clinical Development, Medical Writing, Regulatory, and external vendors to deliver high-quality results on time.
  • Develop, review, and maintain ADaM specifications, TLF shells, programming documentation, reusable macros, and study-level programming standards in alignment with company procedures and regulatory expectations.
  • Provide input into protocols, statistical analysis plans, CRF design and annotation, edit checks, SDTM specifications, integrated data review, and submission strategy to ensure traceability, consistency, and efficient downstream analysis.
  • Support regulatory submission readiness, including preparation and review of define.xml, reviewer guides, submission-ready datasets, and related documentation in compliance with CDISC and global regulatory requirements.
  • Identify programming risks, drive issue resolution, and recommend process improvements that enhance quality, scalability, efficiency, and inspection readiness across studies and programs.
  • Depending on level, mentor junior programmers, provide technical guidance, contribute to resource planning, oversee vendor deliverables, and help shape departmental standards, tools, and best practices.

Qualifications and Skills
  • MS or equivalent degree in Statistics, Biostatistics, Mathematics, Computer Science, or a related discipline; advanced degree preferred.
  • 3+ years relevant statistical programming experience in biotech, pharma, or CRO settings; vendor oversight experience preferred but not required.
  • Strong hands-on expertise in SAS programming, including Base SAS, SAS/STAT, SAS/GRAPH, SAS/SQL, SAS/ODS, and macro development; experience with R or other modern programming tools is a plus.
  • Deep knowledge of CDISC standards, including SDTM, ADaM, define.xml, reviewer guides, and electronic submission requirements in eCTD format.
  • Experience supporting study-level and integrated analyses, including ISS/ISE or other cross-study deliverables, with strong understanding of clinical trial reporting and regulatory submission processes.
  • Able to work independently, manage priorities, collaborate cross-functionally, and deliver high-quality work in a fast-paced environment.
  • For manager-level candidates, experience mentoring programmers, overseeing external vendors, and contributing to resource planning or process improvement is a plus.

This role is based out of our corporate office in Boston, Massachusetts. Rhythm operates in a hybrid-work model. Candidates applying must be willing and able to be in the Boston office in coordination with their department and business needs. This role may involve some travel.
The expected salary range for this position is $90,000 - $135,000. Actual pay will be determined based on experience, level, qualifications, geographic location, and other job-related factors permitted by law. A discretionary annual bonus may be available based on individual and company performance. This role may be eligible for benefits and other compensation such as restricted stock units.
More about Rhythm
We are a dynamic and growing global team spanning more than a dozen countries. At Rhythm we are dedicated to transforming the lives of patients living with rare neuroendocrine diseases by rapidly advancing care and precision medicines that address the root cause.  Our team is passionate about expanding access to reach more patients and developing novel therapies for other rare neuroendocrine diseases, including congenital hyperinsulinism.
 
At Rhythm our core values are:
  • We are committed to advancing scientific understanding to improve patients’ lives
  • We are inspired to tackle tough challenges and have the courage to ask bold questions
  • We are eager to learn and adapt
  • We believe collaboration and ownership are foundational for our success
  • We value the unique contribution each individual brings to furthering our mission

Inherent in our core values is the commitment to act ethically and with integrity in all we do.
Rhythm is an equal employment opportunity employer and does not discriminate against any applicant because of race, creed, color, age, national origin, ancestry, religion, gender, sexual orientation, disability, genetic information, veteran status, military status, application for military service, or any other class protected by state or federal law. 
Headquartered in Boston, Rhythm is proud to have been named one of the Top Places to Work in Massachusetts.

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