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Senior Remote Clinical Operations Jobs (NOW HIRING)

Espresso Clinical

VP of Clinical Operations

Boston, MA · On-site +1

VP of Clinical Operations Espresso Clinical | Boston, MA (East Coast remote considered) Clinical trials still run on five disconnected systems, a spreadsheet, and hope. Sponsors lose visibility the ...

New

Whoop

Director, Clinical Operations

Boston, MA · On-site +1

As the Director, Clinical Operations, you will lead the clinical operations function responsible ... ePRO, eTMF, and remote study platforms. * Oversee study startup and regulatory operations ...

Whoop

Director, Clinical Operations

Boston, MA · On-site +1

As the Director, Clinical Operations, you will lead the clinical operations function responsible ... ePRO, eTMF, and remote study platforms. * Oversee study startup and regulatory operations ...

Alopex

Clinical Operations Director

Las Vegas, NV · On-site +1

$135K - $155K/yr

Clinical Operations Director Overview The Clinical Operations Director is responsible for leading ... Demonstrated experience leading remote or hybrid operational teams * Strong understanding of ...

Guideway Care

Clinical Operations Manager

AL · Remote

This role involves managing a team of remote registered nurses who provide triage services to ... Address escalated patient concerns and work to resolve complex clinical issues. 5. Operational ...

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Senior Remote Clinical Operations information

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$163.5K

How much do senior remote clinical operations jobs pay per year?

As of Jun 15, 2026, the average yearly pay for senior remote clinical operations in the United States is $80,287.00, according to ZipRecruiter salary data. Most workers in this role earn between $41,500.00 and $103,000.00 per year, depending on experience, location, and employer.
What cities are hiring for Senior Remote Clinical Operations jobs? Cities with the most Senior Remote Clinical Operations job openings:
What are the most commonly searched types of Senior Clinical Operations jobs? The most popular types of Senior Clinical Operations jobs are:
What states have the most Senior Remote Clinical Operations jobs? States with the most job openings for Senior Remote Clinical Operations jobs include:
Senior Remote Clinical Operations jobs near you
Infographic showing various Senior Remote Clinical Operations job openings in the United States as of June 2026, with employment types broken down into 1% Locum Tenens, 7% As Needed, 78% Full Time, 10% Part Time, 1% Temporary, and 3% Contract. Highlights an 87% Physical, 5% Hybrid, and 8% Remote job distribution, with an average salary of $80,287 per year, or $38.6 per hour.
Senior Director/Executive Director Clinical Operations

Senior Director/Executive Director Clinical Operations

Lycia Therapeutics

South San Francisco, CA • Remote

$240K - $275K/yr

Full-time

Posted 11 days ago

Job description

Lycia Therapeutics is a biotechnology company using its proprietary lysosomal targeting chimera (LYTAC) platform to discover and develop best-in-class therapeutics that degrade extracellular and membrane-bound proteins. These proteins drive a wide range of difficult-to-treat diseases, including autoimmune and inflammatory conditions. Lycia was established in 2019 in collaboration with academic founder and Nobel Laureate Carolyn Bertozzi, Ph.D., professor of chemistry and HHMI investigator at Stanford University. In May 2024, Lycia Therapeutics completed a $106.6 million Series C financing to advance its pipeline of LYTAC extracellular protein degraders to the clinic. Lycia is headquartered in South San Francisco. 

Visit https://lyciatx.com/ for more information.

The Senior Director/Executive Director Clinical Operations will be responsible for responsible for all functional activities related to execution of Clinical Trials. The incumbent will lead and oversee a team of internal and external clinical project managers/specialists to meet individual clinical trial objectives and corporate goals as well as providing operational expertise to project teams.

Primary Responsibilities:
  • Directs, supervises and manages all aspects of clinical trials to ensure that corporate and department goals/objectives for clinical development programs are met on time and within budget.
  • Interacts with multidisciplinary teams in a matrix environment, developing resourcing, budgeting, financial and strategic planning for clinical programs/studies
  • Create and execute clinical operational strategic plans in line with product strategy and resource allocation.
  • Responsible for, as directed,  strategy and clinical operation sections of regulatory documents including data summarization, protocols, Investigator Brochures, IND annual reports, and others as needed or requested.
  • Prepare and present clinical development trial updates to senior management, review any potential issues and propose any mitigations/recommendations.
  • Develop study feasibility, cost estimates, input into contracts, work/change orders and analyze tools and processes to support outsourcing efforts.
  • Build, develop and train internal staff and external vendors, structure department for enhancing efficiency, and create a highly engaged work environment for attracting and retaining highly qualified clinical operations professionals.
  • Develop and ensure compliance with SOPs and guidelines, FDA regulations and current ICH GCP guidelines.
  • Oversee and maintain the relationships with Contract Research Organizations and  investigative sites,
  • Participate on project teams and study teams as needed or requested.
  • Maintain a high level of professional expertise through familiarity of clinical literature, knowledge of therapeutic area, current medical practice and pharmaceutical regulations.
Additional Expectations
  • Although a remote position, it may be necessary to travel to corporate headquarters up to 2 times per year.
  • Ability to travel to clinical sites or to the CRO, as necessary to support trial management.
Qualifications:
  • B.A/B.S required; M.S., PhD, PharmD, MD or other related advanced scientific degree strongly preferred.
  • Minimum of 10 years for senior director and minimum of 20 years for executive director with progressive advancement within clinical operations in the pharmaceutical/biotech industry.
  • Ability to build collaborative relationships with investigators, vendors, and individuals at all levels of the organization.
  • Flexible and dynamic interpersonal approach, entrepreneurial by nature, a collaborative team player who works well with physicians, scientists, managers, peers, and staff.
  • Ability to manage in a consensus environment through teamwork, trust and shared expectations, influencing strategic direction of complex global clinical operations issues, solicit information, listen well, persuade others, make important decisions and shape outcomes.
The expected base salary range for this role is $240,000-$275,000. We encourage candidates of all levels to apply as there is often flexibility on job title and responsibilities. Compensation will be based on a variety of factors, including experience, qualifications and internal equity. Lycia offers a competitive employment package that includes an annual bonus, equity, and a generous benefits package.
We are an equal opportunity employer and value diversity at our company. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status.

Lycia and other biotech companies have recently noticed an increase in email and social media scams targeting job candidates in our industry. Please note Lycia will post any legitimate job openings directly on our website or through our recruitment partner, Lever. If you wish to verify the legitimacy of a job opening, you may contact us.

We may use artificial intelligence (AI) tools to support parts of the hiring process, such as reviewing applications, analyzing resumes, or assessing responses. These tools assist our recruitment team but do not replace human judgment. Final hiring decisions are ultimately made by humans. If you would like more information about how your data is processed, please contact us.