1

Senior Python Software Engineer Jobs in Indianapolis, IN

Continuously learn and develop your skills through pairing with senior engineers, code review ... Proficiency in Python, demonstrated through coursework, projects, internships, or professional ...

The Software Engineer T1 should have experience developing in one or more C++, Java, and Python languages with strong communication and teaming skills that embrace modern development processes and ...

Software Engineer * Type : W-2 or 1099-Direct Employment * Location : Indianapolis, IN (on-site ... Develop server-side solutions using languages like Java, C#, JavaScript, and Python * Create ...

The Software Engineer T1 should have experience developing in one or more C++, Java, and Python languages with strong communication and teaming skills that embrace modern development processes and ...

We are looking for a talented Sr. IoT Software Engineer to design, configure, and integrate IoT ... Proficiency in Python or similar programming languages and familiarity with relational databases (e ...

Sr. IoT Software Engineer

Indianapolis, IN ยท On-site

$90K - $120K/yr

We are looking for a talented Sr. IoT Software Engineer to design, configure, and integrate IoT ... Proficiency in Python or similar programming languages and familiarity with relational databases (e ...

We are looking for a talented Sr. IoT Software Engineer to design, configure, and integrate IoT ... Proficiency in Python or similar programming languages and familiarity with relational databases (e ...

Sr. Software Engineer

Indianapolis, IN ยท Remote

$150K - $175K/yr

SENIOR SOFTWARE ENGINEER POSITION SUMMARY We are seeking a Sr. Software Engineer and or Jr. Platform Architect to serve as technical lead responsible for day-to-day development, design, build, and ...

Senior Software Engineer

Indianapolis, IN

$117K - $154K/yr

Responsibilities The Senior Software Engineer will be responsible for integrating with third-party APIs, developing web services, coding in the UI and backend (including SQL) and making architecture ...

Senior Software Engineer

Indianapolis, IN

$117K - $154K/yr

Responsibilities The Senior Software Engineer will be responsible for integrating with third-party APIs, developing web services, coding in the UI and backend (including SQL) and making architecture ...

Senior Software Engineer

Indianapolis, IN ยท On-site

$117K - $154K/yr

Responsibilities The Senior Software Engineer will be responsible for integrating with third-party APIs, developing web services, coding in the UI and backend (including SQL) and making architecture ...

Software Engineer * Type : W-2 or 1099-Direct Employment * Location : Indianapolis, IN (on-site ... Develop server-side solutions using languages like Java, C#, JavaScript, and Python * Create ...

Senior Software Engineer- (T04)

Indianapolis, IN ยท On-site

$117K - $154K/yr

V2X is looking for a Senior Software Engineer to join our team! Overview V2X is seeking a highly skilled Senior Software Engineer II to join our Engineering team in Indianapolis, IN supporting ...

Sr. Innovation Software Engineer

Indianapolis, IN ยท On-site +1

$117K - $154K/yr

The Senior Innovation Software Engineer will partner closely across the Innovation team to develop ... Java, Python, TypeScript/JavaScript, or similar) and/or experience leveraging AI-assisted ...

Sr. Innovation Software Engineer

Indianapolis, IN ยท On-site +1

$117K - $154K/yr

The Senior Innovation Software Engineer will partner closely across the Innovation team to develop ... Java, Python, TypeScript/JavaScript, or similar) and/or experience leveraging AI-assisted ...

We're seeking a Software Engineer to join our Patient Experience Cloud (PXC) team. PXC is Zotec ... Python, FastAPI, .NET Core * Front-end: TypeScript and Angular * Cloud and infrastructure: AWS ...

next page

Showing results 1-20

Senior Python Software Engineer information

See Indianapolis, IN salary details

$52.6K

$135.7K

$186.4K

How much do senior python software engineer jobs pay per year?

As of Jun 18, 2026, the average yearly pay for senior python software engineer in Indianapolis, IN is $135,710.00, according to ZipRecruiter salary data. Most workers in this role earn between $116,100.00 and $156,300.00 per year, depending on experience, location, and employer.

What is the difference between Senior Python Software Engineer vs Python Developer?

AspectSenior Python Software EngineerPython Developer
Required CredentialsBachelor's degree in CS or related field, experience in software engineeringBachelor's degree in CS or related field, coding proficiency
Work EnvironmentDesigning complex systems, leading projects, mentoringWriting code, developing applications, debugging
Employer & Industry UsageTech companies, startups, enterprise softwareWeb development, data analysis, automation projects
Common Search & Comparison IntentUnderstanding senior-level roles, responsibilities, and skillsEntry to mid-level coding roles, project involvement

The main difference between a Senior Python Software Engineer and a Python Developer lies in experience, responsibilities, and scope. Senior engineers typically lead projects, design system architecture, and mentor junior staff, while Python Developers focus on coding, application development, and implementation. Both roles require strong Python skills and relevant credentials, but senior roles demand more experience and leadership capabilities.

What are some common challenges faced by Senior Python Software Engineers when leading complex projects, and how can they be addressed?

Senior Python Software Engineers often face challenges such as balancing hands-on coding with mentoring junior team members, managing technical debt, and designing scalable solutions. Successfully addressing these challenges involves clear communication, proactive code reviews, and effective prioritization of tasks. Collaborating closely with cross-functional teams and fostering a culture of knowledge sharing can also help ensure project success and team growth.

What is the salary of senior Python developer?

The salary of a senior Python software engineer typically ranges from $100,000 to $150,000 annually, depending on experience, location, and industry. Skilled professionals with expertise in frameworks like Django or Flask and experience with cloud services may earn higher compensation.

Will AI replace Python coders?

AI tools can automate certain coding tasks, but Senior Python Software Engineers are essential for designing, developing, and maintaining complex software systems. AI is more likely to augment coding work rather than fully replace experienced developers, who bring problem-solving, creativity, and domain expertise that AI cannot replicate fully.

What are the key skills and qualifications needed to thrive as a Senior Python Software Engineer, and why are they important?

To thrive as a Senior Python Software Engineer, you need advanced proficiency in Python programming, strong problem-solving abilities, and a solid background in computer science or a related field. Familiarity with frameworks like Django or Flask, experience with version control systems such as Git, and knowledge of cloud platforms and CI/CD tools are typically required. Leadership, effective communication, and mentorship skills help you collaborate with teams and guide junior developers. These skills ensure the delivery of robust, scalable software solutions and foster a productive, innovative development environment.

What engineers make $500,000?

Senior Python Software Engineers with extensive experience, specialized skills in areas like machine learning or data engineering, and working in high-paying industries such as finance or tech can earn $500,000 or more annually. Compensation often includes base salary, bonuses, and stock options, especially at large tech companies or startups with significant funding.

What does a Senior Python Software Engineer do?

A Senior Python Software Engineer designs, develops, tests, and maintains complex software applications using the Python programming language. They often lead or mentor junior developers, architect software solutions, and ensure best coding practices are followed. These professionals collaborate with cross-functional teams to deliver scalable and efficient systems, troubleshoot issues, and optimize application performance. Their expertise includes advanced knowledge of Python frameworks, libraries, and development tools, as well as experience with databases, APIs, and cloud services.

Is it possible to make 300k as a software engineer?

Senior Python software engineers with extensive experience, specialized skills, and working in high-paying industries or companies can reach or exceed a $300,000 annual salary, especially with bonuses and stock options. Achieving this level often requires advanced knowledge of frameworks, cloud platforms, and a strong track record of project success.
What are popular job titles related to Senior Python Software Engineer jobs in Indianapolis, IN? For Senior Python Software Engineer jobs in Indianapolis, IN, the most frequently searched job titles are:
What job categories do people searching Senior Python Software Engineer jobs in Indianapolis, IN look for? The top searched job categories for Senior Python Software Engineer jobs in Indianapolis, IN are:
What cities near Indianapolis, IN are hiring for Senior Python Software Engineer jobs? Cities near Indianapolis, IN with the most Senior Python Software Engineer job openings:
Infographic showing various Senior Python Software Engineer job openings in Indianapolis, IN as of June 2026, with employment types broken down into 1% As Needed, 91% Full Time, 1% Part Time, 6% Contract, and 1% Nights. Highlights an 87% Physical, 5% Hybrid, and 8% Remote job distribution, with an average salary of $135,710 per year, or $65.2 per hour.
Software Engineer

Software Engineer

CALRegional

Indianapolis, IN โ€ข On-site, Remote

Full-time

Medical, Dental, Vision, Life

Posted 9 days ago


Job description

Make Anย Impact!ย ย 

Are you aย self-motivated developerย eager to grow your skillsย andย looking to make a real difference in people's lives?ย Come beย a part of our #calregionalfamily as aย Software Engineerย and help develop the heroes of tomorrow.ย 

-------------------------------------------------------ย 

Whoย Weโ€™reย Looking Forย 

We are looking for an enthusiastic and self-motivated full-timeย Software Engineerto join our team at ourย location inย Indianapolis, IN.ย This role is open to candidates ranging from recent graduates to engineers with a few years of professional experience.ย We are interested in candidates who are looking to work for a company that is passionate about changing lives and helping build the essential workforce!ย ย 

Theย Software Engineerโ€™s duties and responsibilities include:ย 

  • Develop,ย test,ย and deploy software applications, making sound implementation decisions within established architectural directionย 

  • Build and maintainย microservicesย that integrate with internal and third-party APIsย 

  • Contribute toย backend integrations with CRM platformsย 

  • Support and contribute toย CI/CD pipelines for web applications and APIsย 

  • Participate in code reviews, both giving and receiving feedback, and follow established code qualityย standardsย 

  • Contribute to automation and workflow improvements, including projects involving LLM and generative AI solutionsย 

  • Continuously learn and develop your skills through pairing with senior engineers, code review feedback, and exposure to a wide range of technical challengesย 

  • Performย other responsibilities and projects as directed by the Chief Technology Officerย 

The Skills You Need:ย ย ย 

  • 0-3ย years of professional software development experienceย 

  • Proficiencyย in Python,ย demonstratedย through coursework, projects, internships, or professional experienceย 

  • Familiarity with at least one major cloud platform (GCP, AWS, or Azure), through coursework, personal projects, or professional experienceย 

  • Experienceย creating web pages withย HTML, CSS, and JavaScriptย 

  • Experience working with relational databases(Postgres preferred)ย 

  • Experienceย withย RESTful APIsย 

  • Understanding of object-oriented programmingย fundamentalsย andย Agileย methodologyย 

  • Experience with Git and collaborative development workflows (pull requests, code reviews)ย 

  • Strong written and verbal communication skills, with the ability to explain your work clearlyย 

  • Demonstrated coding ability through one or more of the following: a CS or related degree, a coding bootcamp, significant open-source or personal projects, or relevant work experienceย 

Even Better If You Have:ย ย 

  • Bachelor's degree in computer science or related field or equivalent work experienceย 

  • Any cloud platform certification (GCP Associate Cloud Engineer, AWS Cloud Practitioner, Azure Fundamentals, or similar)ย 

  • CRM experience, such as Zohoย orย Salesforceย 

  • Exposure to generative AI tools, LLM APIs, or AI-assisted development workflowsย 

  • Experience with Django or another Python web framework (Flask,ย FastAPI,ย etc)ย 

  • Contributions to open-source projects or a portfolio of personal projectsย 

-------------------------------------------------------ย 

What We Offerย ย 

We offer generous pay along withย healthย benefits we are proud of. Our health benefits include medical, dental, vision, and complimentary life insurance plans.ย 

We offer discretionary bonuses, raises, and promotions based on company and personal performance. We are known for rewarding our employees and sharing our successes with the team.ย ย ย 

We value work-life balance and self-care. Our work schedule is based on a 34-hour work week, giving our employees more time to take care ofย personalย needs. This specific position follows a hybrid schedule and can be worked remotely up toย 3ย days a week.ย ย 

-------------------------------------------------------ย 

Who We Areย 

CALRegional specializes in administering healthcare training programs for public institutions in California, Texas, and Arizona. We provide affordable, fast-paced programs that positivelyย impactย the lives of students and the communities we serve together. Having started in 2013, our team has a great amount of experience helping public institutions expand their healthcare program offerings to meet the demands of businesses in the local community.ย 

Since our start, CALRegional has grown over 30% each year.ย Weโ€™veย created new career opportunities to strengthen our team and continue our mission of providing students with high-qualityย affordable healthcare career education programs and to help build the essential workforce.ย ย 

-------------------------------------------------------ย 

Our Cultureย 

Atย CALRegional, our mission is to create and sustain a culture based on our core values ofย Trust,ย Loyalty,ย Teamwork,ย Commitment,ย Consistency,ย Honesty, andย Expertise. Upholding these values is the cornerstone of our success in cultivating a culture that develops strong and genuineworkingrelationships.We strive to empower our employees to do their best work through personal growth and development.ย 

Weโ€™veย fostered a culture that promotes constructive discussion and the prioritization of student success. We discourage departmental silos and encourage constructive feedback and ideas from all individuals in the company.ย ย