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Senior Python Software Engineer Jobs in Columbia, MD

Software Engineer, Senior

Mclean, VA · On-site

$124K - $163K/yr

Software Engineer, Senior JOB SUMMARY Are you looking for more than just a seat on a contract? Are ... Skyline Scientific is looking for a strong Python software engineer who is excited to work on ...

Sr. Python Developer

Mclean, VA · On-site

$123K - $166K/yr

Design, develop and support software solution for the given requirements within the financial ... Engineering or related technical field Demonstrated knowledge of: * Python, Pandas and other ...

Sr. Python Developer

Mclean, VA · On-site

$51.50 - $71/hr

Master s degree or foreign equivalent degree in Computer Science, Software Engineering or related ... Python, Python web technologies, e.g. Flask, Dash * Python data processing technologies, e.g.

Software Engineer

Annapolis Junction, MD · On-site

$57.70 - $91.35/hr

As a software engineer, you know that good software is more than just a nice-looking interface ... Experience with Java, Python, C#, C/C++, .NET, JavaScript, React, NodeJS, PHP, or Drupal

Senior Software Engineer - Python

Rockville, MD · On-site +1

$124K - $164K/yr

... Software Engineer to join our agile and exceptionally talented engineering team. As a Senior ... Having extensive Python + Django experience is required. The project is unique as it is a well ...

Senior Software Engineer - Python

Rockville, MD · Remote

$124K - $164K/yr

... Software Engineer to join our agile and exceptionally talented engineering team. As a Senior ... Having extensive Python + Django experience is required. The project is unique as it is a well ...

Software Engineer

Annapolis Junction, MD · On-site

$57.70 - $91.35/hr

Responsibilities As a software engineer, you know that good software is more than just a nice ... Experience with Java, Python, C#, C/C++, .NET, JavaScript, React, NodeJS, PHP, or Drupal

Software Engineer

Annapolis Junction, MD · On-site

$57.70 - $91.35/hr

Job Title Software Engineer Overview EverWatch is a government solutions company providing advanced ... Experience with Java, Python, C#, C/C++, .NET, JavaScript, React, NodeJS, PHP, or Drupal

We are looking for a Senior Python Engineer with a "hacker" mindset to join our team as a Software Engineer III. This role is dedicated to large-scale web scraping and data harvesting. If you have ...

Software Engineer

Annapolis Junction, MD · On-site

$57.70 - $91.35/hr

Responsibilities As a software engineer, you know that good software is more than just a nice ... Experience with Java, Python, C#, C/C++, .NET, JavaScript, React, NodeJS, PHP, or Drupal

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Senior Python Software Engineer information

See Columbia, MD salary details

$54.6K

$140.9K

$193.5K

How much do senior python software engineer jobs pay per year?

As of Jul 8, 2026, the average yearly pay for senior python software engineer in Columbia, MD is $140,896.00, according to ZipRecruiter salary data. Most workers in this role earn between $120,600.00 and $162,300.00 per year, depending on experience, location, and employer.

What is the difference between Senior Python Software Engineer vs Python Developer?

AspectSenior Python Software EngineerPython Developer
Required CredentialsBachelor's degree in CS or related field, experience in software engineeringBachelor's degree in CS or related field, coding proficiency
Work EnvironmentDesigning complex systems, leading projects, mentoringWriting code, developing applications, debugging
Employer & Industry UsageTech companies, startups, enterprise softwareWeb development, data analysis, automation projects
Common Search & Comparison IntentUnderstanding senior-level roles, responsibilities, and skillsEntry to mid-level coding roles, project involvement

The main difference between a Senior Python Software Engineer and a Python Developer lies in experience, responsibilities, and scope. Senior engineers typically lead projects, design system architecture, and mentor junior staff, while Python Developers focus on coding, application development, and implementation. Both roles require strong Python skills and relevant credentials, but senior roles demand more experience and leadership capabilities.

What are some common challenges faced by Senior Python Software Engineers when leading complex projects, and how can they be addressed?

Senior Python Software Engineers often face challenges such as balancing hands-on coding with mentoring junior team members, managing technical debt, and designing scalable solutions. Successfully addressing these challenges involves clear communication, proactive code reviews, and effective prioritization of tasks. Collaborating closely with cross-functional teams and fostering a culture of knowledge sharing can also help ensure project success and team growth.

What are the key skills and qualifications needed to thrive as a Senior Python Software Engineer, and why are they important?

To thrive as a Senior Python Software Engineer, you need advanced proficiency in Python programming, strong problem-solving abilities, and a solid background in computer science or a related field. Familiarity with frameworks like Django or Flask, experience with version control systems such as Git, and knowledge of cloud platforms and CI/CD tools are typically required. Leadership, effective communication, and mentorship skills help you collaborate with teams and guide junior developers. These skills ensure the delivery of robust, scalable software solutions and foster a productive, innovative development environment.

What does a Senior Python Software Engineer do?

A Senior Python Software Engineer designs, develops, tests, and maintains complex software applications using the Python programming language. They often lead or mentor junior developers, architect software solutions, and ensure best coding practices are followed. These professionals collaborate with cross-functional teams to deliver scalable and efficient systems, troubleshoot issues, and optimize application performance. Their expertise includes advanced knowledge of Python frameworks, libraries, and development tools, as well as experience with databases, APIs, and cloud services.
What are popular job titles related to Senior Python Software Engineer jobs in Columbia, MD? For Senior Python Software Engineer jobs in Columbia, MD, the most frequently searched job titles are:
What job categories do people searching Senior Python Software Engineer jobs in Columbia, MD look for? The top searched job categories for Senior Python Software Engineer jobs in Columbia, MD are:
What cities near Columbia, MD are hiring for Senior Python Software Engineer jobs? Cities near Columbia, MD with the most Senior Python Software Engineer job openings:
Software Engineer - Python

Software Engineer - Python

Interclypse, Inc.

Annapolis Junction, MD

$55.25 - $76/hr

Other

Medical, Dental, Vision, Life, Retirement, PTO

Re-posted 24 days ago


Job description

Description

Interclypse is seeking a Senior Python Developer to support a federal agency's migration from a legacy OpenVMS/Itanium server infrastructure and DCL scripting environment to a modern Python-based middleware platform. You will work as part of a small, senior developer team under the agency's technical direction, writing production-quality Python code within a disciplined Agile/DevSecOps framework. This is a Firm-Fixed-Price engagement - we expect self-directed professionals who take ownership of deliverables and meet acceptance criteria without heavy management oversight.nt.


Key Responsibilities

Develop Python/FastAPI middleware services that replace legacy OpenVMS DCL script processing, including POLLVAX, TO_FDSYS, and other identified batch scripts

Build file processing pipelines, data routing engines, hot folder watchers, and workflow management components

Implement a dual-mode delivery system supporting both legacy share emulation and modern REST API access

Develop SSO-integrated authentication and authorization, user and role management, and audit logging

Create Axway FTP server integration for congressional file intake and Windows NAS connectivity for file storage

Build task queuing systems, database integration for metadata tracking, and event-driven processing with real-time file monitoring

Implement automated backup, error recovery/retry mechanisms, and performance optimization for concurrent client connections

Design and execute a comprehensive testing framework including unit, integration, and UAT automated test suites

Participate in 2-week Agile sprints, bi-weekly demos, and DevSecOps gates under agency direction

Contribute to monthly status reports, development logs, sprint code releases, and support documentation

Requirements

Interclypse provides a uniquely cultivating environment where mentorship and continued learning create extraordinary professionals. Our goal is to empower our talent by putting you in the driver's seat of your career.

Software Engineering candidates have experience working in team environments, building software solutions for customers, and are looking to take their careers to the next level. Familiarity with the following tech stacks below is great but not a requirement.


Required Qualifications

Develop Python/FastAPI middleware services that replace legacy OpenVMS DCL script processing, including POLLVAX, TO_FDSYS, and other identified batch scripts

Build file processing pipelines, data routing engines, hot folder watchers, and workflow management components

Implement a dual-mode delivery system supporting both legacy share emulation and modern REST API access

Develop SSO-integrated authentication and authorization, user and role management, and audit logging

Create Axway FTP server integration for congressional file intake and Windows NAS connectivity for file storage

Build task queuing systems, database integration for metadata tracking, and event-driven processing with real-time file monitoring

Implement automated backup, error recovery/retry mechanisms, and performance optimization for concurrent client connections

Design and execute a comprehensive testing framework including unit, integration, and UAT automated test suites

Participate in 2-week Agile sprints, bi-weekly demos, and DevSecOps gates under agency direction

Contribute to monthly status reports, development logs, sprint code releases, and support documentation


Preferred Qualifications

Develop Python/FastAPI middleware services that replace legacy OpenVMS DCL script processing, including POLLVAX, TO_FDSYS, and other identified batch scripts

Build file processing pipelines, data routing engines, hot folder watchers, and workflow management components

Implement a dual-mode delivery system supporting both legacy share emulation and modern REST API access

Develop SSO-integrated authentication and authorization, user and role management, and audit logging

Create Axway FTP server integration for congressional file intake and Windows NAS connectivity for file storage

Build task queuing systems, database integration for metadata tracking, and event-driven processing with real-time file monitoring

Implement automated backup, error recovery/retry mechanisms, and performance optimization for concurrent client connections

Design and execute a comprehensive testing framework including unit, integration, and UAT automated test suites

Participate in 2-week Agile sprints, bi-weekly demos, and DevSecOps gates under agency direction

Contribute to monthly status reports, development logs, sprint code releases, and support documentation

Our favorite candidates are resilient problem solvers, cooperative teammates, and passionate innovators.


Why You Might Like This Job:

  • You're tired of working for a massive organization.
  • You want to work for an established company that values your stable career.
  • You want to work with a team that loves their job and making cool stuff.
  • You want to be part of a team focused on making a positive impact.
  • You want to grow your skills in management or work toward becoming an expert.
  • You want to have the option for career mentorship, both in technology and in business.
  • You value a company with a strong culture of growth and support

Benefits:

  • Employee Impact Program. Every employee has the opportunity to define and get rewarded for their contributions they can make toward the long-term health of the company, customer, and employee. This program in combination with our comprehensive time off and leave programs allow you to design a career and compensation program that enables near infinite flexibility while ensuring both company, customer, and individual health and prosperity.
  • Comprehensive time off and leave programs:
    • 31 Days (248 hours) of Paid Personal Time Off (PTO) for any vacation, holidays, illnesses, and birthdays
    • Parental Leave: 40 Hours
    • Bereavement Leave: 24 hours.
    • Military Reserve Leave (up to 80 hours, see employee handbook for details).
    • Jury Duty Leave 16 hours.
  • Retirement: Unlimited 401K match up to 8% of your salary up to the federal maximum
  • Health Insurance (Medical, Dental, Vision): Premium is 100% company paid (contact us for specific plan details).
  • Health Savings Account (HSA): Interclypse contributes $750 for individuals and $1500 for families
  • Vision Insurance
  • Dental Insurance includes orthodontics coverage
  • Life Insurance
  • Accidental Death and Dismemberment Insurance
  • Disability: Short-term and long-term disability coverage
  • Educational support: reimbursement up to the federal max of $5,250
  • Company apparel: $200 for company apparel each year
  • Social events: Holiday Party, Spring Picnic, Fall Picnic, happy hours and more

Interclypse isn't your typical company. We strive to have a positive & transformational impact on our community, our industry, and individuals. We keep this focus through our motto: "Doing What is Right". Apply today to see how you can join our winning team and start down the career path that's right for you!


EOE AA M/F/Vet/Disability:

Interclypse is an Equal Opportunity/Affirmative Action employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, creed, sex, sexual orientation, gender identity, national origin, disability, or protected Veteran status.

Related terms and topics: Java, Software Development, Computer Programming, Software Engineering, C++, Design Patterns, Enterprise Integration Patterns