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Senior Python Software Engineer Jobs in Baltimore, MD

CNO Python Software Engineer

Hanover, MD

$49.50 - $68.25/hr

MANTECH seeks a motivated, career- and customer-oriented CNO Python Software Engineer to join our team in Hanover, MD. This position supports critical mission requirements by delivering advanced ...

CNO Python Software Engineer

Hanover, MD

$49.50 - $68.25/hr

MANTECH seeks a motivated, career- and customer-oriented CNO Python Software Engineer to join our team in Hanover, MD. This position supports critical mission requirements by delivering advanced ...

CNO Python Software Engineer

Hanover, MD ยท On-site

$114K - $190K/yr

MANTECH seeks a motivated, career- and customer-oriented CNO Python Software Engineer to join our team in Hanover, MD. This position supports critical mission requirements by delivering advanced ...

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Showing results 1-20

Senior Python Software Engineer information

See Baltimore, MD salary details

$54.6K

$141.1K

$193.8K

How much do senior python software engineer jobs pay per year?

As of Jun 18, 2026, the average yearly pay for senior python software engineer in Baltimore, MD is $141,072.00, according to ZipRecruiter salary data. Most workers in this role earn between $120,700.00 and $162,500.00 per year, depending on experience, location, and employer.

What is the difference between Senior Python Software Engineer vs Python Developer?

AspectSenior Python Software EngineerPython Developer
Required CredentialsBachelor's degree in CS or related field, experience in software engineeringBachelor's degree in CS or related field, coding proficiency
Work EnvironmentDesigning complex systems, leading projects, mentoringWriting code, developing applications, debugging
Employer & Industry UsageTech companies, startups, enterprise softwareWeb development, data analysis, automation projects
Common Search & Comparison IntentUnderstanding senior-level roles, responsibilities, and skillsEntry to mid-level coding roles, project involvement

The main difference between a Senior Python Software Engineer and a Python Developer lies in experience, responsibilities, and scope. Senior engineers typically lead projects, design system architecture, and mentor junior staff, while Python Developers focus on coding, application development, and implementation. Both roles require strong Python skills and relevant credentials, but senior roles demand more experience and leadership capabilities.

What are some common challenges faced by Senior Python Software Engineers when leading complex projects, and how can they be addressed?

Senior Python Software Engineers often face challenges such as balancing hands-on coding with mentoring junior team members, managing technical debt, and designing scalable solutions. Successfully addressing these challenges involves clear communication, proactive code reviews, and effective prioritization of tasks. Collaborating closely with cross-functional teams and fostering a culture of knowledge sharing can also help ensure project success and team growth.

What is the salary of senior Python developer?

The salary of a senior Python software engineer typically ranges from $100,000 to $150,000 annually, depending on experience, location, and industry. Skilled professionals with expertise in frameworks like Django or Flask and experience with cloud services may earn higher compensation.

Will AI replace Python coders?

AI tools can automate certain coding tasks, but Senior Python Software Engineers are essential for designing, developing, and maintaining complex software systems. AI is more likely to augment coding work rather than fully replace experienced developers, who bring problem-solving, creativity, and domain expertise that AI cannot replicate fully.

What are the key skills and qualifications needed to thrive as a Senior Python Software Engineer, and why are they important?

To thrive as a Senior Python Software Engineer, you need advanced proficiency in Python programming, strong problem-solving abilities, and a solid background in computer science or a related field. Familiarity with frameworks like Django or Flask, experience with version control systems such as Git, and knowledge of cloud platforms and CI/CD tools are typically required. Leadership, effective communication, and mentorship skills help you collaborate with teams and guide junior developers. These skills ensure the delivery of robust, scalable software solutions and foster a productive, innovative development environment.

What engineers make $500,000?

Senior Python Software Engineers with extensive experience, specialized skills in areas like machine learning or data engineering, and working in high-paying industries such as finance or tech can earn $500,000 or more annually. Compensation often includes base salary, bonuses, and stock options, especially at large tech companies or startups with significant funding.

What does a Senior Python Software Engineer do?

A Senior Python Software Engineer designs, develops, tests, and maintains complex software applications using the Python programming language. They often lead or mentor junior developers, architect software solutions, and ensure best coding practices are followed. These professionals collaborate with cross-functional teams to deliver scalable and efficient systems, troubleshoot issues, and optimize application performance. Their expertise includes advanced knowledge of Python frameworks, libraries, and development tools, as well as experience with databases, APIs, and cloud services.

Is it possible to make 300k as a software engineer?

Senior Python software engineers with extensive experience, specialized skills, and working in high-paying industries or companies can reach or exceed a $300,000 annual salary, especially with bonuses and stock options. Achieving this level often requires advanced knowledge of frameworks, cloud platforms, and a strong track record of project success.
What are popular job titles related to Senior Python Software Engineer jobs in Baltimore, MD? For Senior Python Software Engineer jobs in Baltimore, MD, the most frequently searched job titles are:
What job categories do people searching Senior Python Software Engineer jobs in Baltimore, MD look for? The top searched job categories for Senior Python Software Engineer jobs in Baltimore, MD are:
What cities near Baltimore, MD are hiring for Senior Python Software Engineer jobs? Cities near Baltimore, MD with the most Senior Python Software Engineer job openings:
Senior Python Software Engineer

Senior Python Software Engineer

GliaCell Technologies

Linthicum Heights, MD โ€ข On-site

Full-time

Medical, Dental, Vision, Life, Retirement, PTO

Posted 9 days ago

Be an early applicant


Job description

***An active or rein-statable TS/SCI with Polygraph security clearance is REQUIRED. Please do not apply if you currently do not possess this level of clearance.***
Are you a Senior Python Software Engineerย who is ready for aย new challengeย that willย launch your careerย to the next level?

  • Tired of being treated like a company drone?
  • Tired of promised adventures during the hiring phase, then dropped off on a remote contract and never seen or heard from the mothership again?
  • Our engineers were certainly tired of the same.ย ย 

At GliaCell our slogan is โ€œWe make It happenโ€.

  • We will immerse you in the latest technologies.
  • We will develop and support your ownย personalized training program to continue your individual growth.ย 
  • We will provide you withย work that mattersย with our mission focused customers, and surround you withย a family of brilliant engineers.ย 

Culture isnโ€™t something you need to talk aboutโ€ฆif it just exists.ย 

If thisย sounds interesting to you, then weโ€™d like toย have a discussion regarding your next adventure!ย If you want to be a drone, this isnโ€™t the place for you.

We Make It Happen!

GliaCell Technologies focuses on Software & System Engineering in Enterprise and Cyber Security solution spaces. We excel at delivering stable and reliable software solutions using Agile Software Development principles. These provide us the capability to deliver a quick turn-around using interactive applications and the integration of industry standard software stacks.

GliaCellโ€™s Enterprise capabilities include Full-Stack Application Development, Big Data, Cloud Technologies, Analytics, Machine Learning, AI, and DevOps Containerization. We also provide customer solutions in the areas of CND, CNE, and CNO by providing our customers with assessments and solutions in Threat Mitigation, Vulnerability Exposure, Penetration Testing, Threat Hunting, and Preventing Advanced Persistent Threat.

We Offer:

  • Long term job security
  • Competitive salaries & bonus opportunities
  • Challenging work you are passionate about
  • Ability to work with some amazingly talented people

Job Description:

GliaCell is seeking a Senior Python Software Engineerย on one of our subcontracts. This is a full-time position offering the opportunity to support a U.S. Government customer. The mission is to provide technical expertise that assists in sustaining critical mission-related software and systems to a large government contract.

Key Requirements:

To be considered for this position you must have the following:

  • Possess an active or rein-statable TS/SCI with Polygraph security clearance.
  • U.S. Citizenship.
  • 6+ years Software Engineering experience and a MSย degree in Computer Science or related, orย 8+ years of experience and a BS Degree, or 10+ years of experience and an AA Degree, or +12 years of experience and a High School Diploma
  • Works well independently as well as on a team.ย 
  • Strong communication skills.ย 

Key Skills:

  • Strong Python development skills
  • A minimum of 5 years of Python experience the past 5 years.
  • AWS Experience
  • Gitlab CI/CD
  • Docker
  • Library Development/Maintenance
  • Experience in several of the following areas: statistical analysis, data mining, advanced analytics, data management, machine learning, or artificial intelligence.
  • Experience with developing cyber security related analytics.
  • Experience with running analytics against large data repositories.
  • Work with SMEs to identify relevant information from data sources.

Desired Skills:

  • Elasticsearch/Splunk
  • Kubernetes
  • Ansible
  • Grafana

Location:ย Linthicum Heights, MD

Salary Range:ย The salary range for this full-time position is $170,000 to $260,000. Our salary ranges are determined by position, level, skills, professional experience, relevant education and certifications. The range displayed on each job posting reflects the minimum and maximum target salaries for this position across our projects. Within the range, your salary is determined by your individual benefits package selection. Your recruiter can share more about the specific salary range for your preferred position during the hiring process. SIGN-ON BONUS ELIGIBLE.

Benefits:

  • CareFirst Medical Coverage for Employee and Dependentsย 
  • Guardian Dental andย Vision Coverage for Employee and Dependentsย 
  • Up to 25 Daysย of Paid Time Off
  • Up to 40 hours of PTO Carryover
  • 11 Federal Government Holidays
  • Work From Home Opportunities
  • 401K Company Contribution, Fully Vested Day 1
  • Discretionary, Certification, and Sign-On Bonus Potentialย 
  • Employee Referral Bonus Programย 
  • Annual Professional Developmentย 
  • 100% Premium Covered for Life & Disability Insurances
  • Additional Voluntary Life Insurance Coverage Availableย 
  • Employee Assistance Program
  • Travel Protection Program
  • Financial Planning Assistanceย 
  • Bereavement and Jury Duty Leave
  • Monthly Team and Family Events
  • Technology Budget
  • Global Entry
  • Annual Swag Budget

Learn more about GliaCell Technologies:ย https://gliacelltechnologies.applytojob.com/apply/

To apply for this position, respond to this job posting and attach an updated resume for us to review.ย 

GliaCell Technologies, LLC is an Equal Opportunity/Affirmative Action Employer.ย All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, age, protected veteran status, or disability status.

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