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Senior Python Software Engineer Jobs in Columbia, MD

BTree Solutions, Inc.

SR. PYTHON DEVELOPER

Reston, VA · On-site

$126K - $170K/yr

Job Title: SR. PYTHON DEVELOPER Location: Reston,VA Duration: 12+ Months Visa: USC, GC, H1B and EAD Contract Type: W2 Development : * Python Developer with experience in Java as a plus. * Proficient ...

Skyline Scientific Inc

Software Engineer, Senior

Mclean, VA · On-site

$124K - $163K/yr

Software Engineer, Senior JOB SUMMARY Are you looking for more than just a seat on a contract? Are ... Skyline Scientific is looking for a strong Python software engineer who is excited to work on ...

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All JobsPython Software Engineer JobsSenior Python Software Engineer JobsSenior Python Software Engineer Jobs in Columbia, MD

Senior Python Software Engineer information

See Columbia, MD salary details

$54.6K

$140.9K

$193.5K

How much do senior python software engineer jobs pay per year?

As of Jul 8, 2026, the average yearly pay for senior python software engineer in Columbia, MD is $140,896.00, according to ZipRecruiter salary data. Most workers in this role earn between $120,600.00 and $162,300.00 per year, depending on experience, location, and employer.

What is the difference between Senior Python Software Engineer vs Python Developer?

AspectSenior Python Software EngineerPython Developer
Required CredentialsBachelor's degree in CS or related field, experience in software engineeringBachelor's degree in CS or related field, coding proficiency
Work EnvironmentDesigning complex systems, leading projects, mentoringWriting code, developing applications, debugging
Employer & Industry UsageTech companies, startups, enterprise softwareWeb development, data analysis, automation projects
Common Search & Comparison IntentUnderstanding senior-level roles, responsibilities, and skillsEntry to mid-level coding roles, project involvement

The main difference between a Senior Python Software Engineer and a Python Developer lies in experience, responsibilities, and scope. Senior engineers typically lead projects, design system architecture, and mentor junior staff, while Python Developers focus on coding, application development, and implementation. Both roles require strong Python skills and relevant credentials, but senior roles demand more experience and leadership capabilities.

What are some common challenges faced by Senior Python Software Engineers when leading complex projects, and how can they be addressed?

Senior Python Software Engineers often face challenges such as balancing hands-on coding with mentoring junior team members, managing technical debt, and designing scalable solutions. Successfully addressing these challenges involves clear communication, proactive code reviews, and effective prioritization of tasks. Collaborating closely with cross-functional teams and fostering a culture of knowledge sharing can also help ensure project success and team growth.

What are the key skills and qualifications needed to thrive as a Senior Python Software Engineer, and why are they important?

To thrive as a Senior Python Software Engineer, you need advanced proficiency in Python programming, strong problem-solving abilities, and a solid background in computer science or a related field. Familiarity with frameworks like Django or Flask, experience with version control systems such as Git, and knowledge of cloud platforms and CI/CD tools are typically required. Leadership, effective communication, and mentorship skills help you collaborate with teams and guide junior developers. These skills ensure the delivery of robust, scalable software solutions and foster a productive, innovative development environment.

What does a Senior Python Software Engineer do?

A Senior Python Software Engineer designs, develops, tests, and maintains complex software applications using the Python programming language. They often lead or mentor junior developers, architect software solutions, and ensure best coding practices are followed. These professionals collaborate with cross-functional teams to deliver scalable and efficient systems, troubleshoot issues, and optimize application performance. Their expertise includes advanced knowledge of Python frameworks, libraries, and development tools, as well as experience with databases, APIs, and cloud services.
What are popular job titles related to Senior Python Software Engineer jobs in Columbia, MD? For Senior Python Software Engineer jobs in Columbia, MD, the most frequently searched job titles are:
What job categories do people searching Senior Python Software Engineer jobs in Columbia, MD look for? The top searched job categories for Senior Python Software Engineer jobs in Columbia, MD are:
What cities near Columbia, MD are hiring for Senior Python Software Engineer jobs? Cities near Columbia, MD with the most Senior Python Software Engineer job openings:
Senior Python Software Engineer jobs near you
Senior Python Engineer -- TS/SCI Cleared (Hybrid/Remote) (Annapolis)

Senior Python Engineer -- TS/SCI Cleared (Hybrid/Remote) (Annapolis)

GliaCell Technologies

Annapolis, MD • On-site

Full-time

Medical

This job post has expired today. Applications are no longer accepted.

Job description

GliaCell Technologies is looking for a Principal Python Software Engineer in Annapolis Junction, Maryland. This full-time role involves supporting a U.S. Government contract, contributing technical expertise to sustain crucial software systems. The ideal candidate should possess an active TS/SCI with Polygraph clearance and have over 20 years of software engineering experience, along with a Bachelor's degree in Computer Science or related. Benefits include competitive salaries, sign-on bonuses, and comprehensive medical coverage.
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