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Senior Python Developer Jobs in Memphis, TN (NOW HIRING)

Deloitte

Finance Analytics & AI Senior Consultant

Memphis, TN · On-site

$113K/yr

... Python and Structured Query Language (SQL) to develop analytics, machine learning, data engineering ... Our Senior Consultants are expected to contribute to the firm's growth and development in a variety ...

Sonsoft Inc

Sr. Data Scientist

Memphis, TN · On-site

Senior data scientist. * Research various analytical approaches * Recommend and develop ... Must be proficient in programming either R/Python/Scala. * Should have experience in Financial ...

FedEx Group

Sr. Revenue Science Analyst

Collierville, TN · On-site

$90 - $130/hr

... programming languages (e.g. SAS, SQL, Python, C, VB.net, Java, JavaScript or R), relational ... Mentors and trains professionals in less senior positions within the team on quantitative data ...

New

FedEx Group

Sr Data Scientist

Collierville, TN · On-site

$85 - $187/hr

Proven leadership skills. * Strong Python skills (data pipelines, automation, scripting ... science or data engineering roles * Experience with medallion (bronze/silver/gold) data ...

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All JobsPython Developer JobsSenior Python Developer JobsSenior Python Developer Jobs in Memphis, TN

Senior Python Developer information

See Memphis, TN salary details

$53.4K

$137.9K

$189.4K

How much do senior python developer jobs pay per year?

As of Aug 20, 2026, the average yearly pay for senior python developer in Memphis, TN is $137,924.00, according to ZipRecruiter salary data. Most workers in this role earn between $118,000.00 and $158,800.00 per year, depending on experience, location, and employer.

What are the main responsibilities of a senior Python developer?

A Senior Python Developer is responsible for designing, developing, and maintaining complex software applications using the Python programming language. They lead the technical aspects of projects, mentor junior developers, and ensure code quality through code reviews and best practices. Additionally, they collaborate with cross-functional teams to gather requirements, solve technical challenges, and deploy scalable and efficient solutions. Senior Python Developers are also expected to stay updated with the latest trends and advancements in Python and related technologies.

What are the key skills and qualifications needed to thrive as a senior Python developer?

To thrive as a Senior Python Developer, you need advanced proficiency in Python programming, experience with software architecture, and a solid understanding of algorithms and data structures, usually backed by a degree in computer science or related fields. Familiarity with frameworks like Django or Flask, version control systems such as Git, and containerization tools like Docker are typically required, alongside knowledge of modern CI/CD pipelines. Strong problem-solving abilities, effective communication, and leadership skills help you collaborate with teams and mentor junior developers. Mastery of these skills ensures the delivery of scalable, maintainable software solutions and the ability to drive technical excellence within development teams.

What are some common challenges faced by senior Python developers when leading a development team?

Senior Python Developers often encounter challenges such as balancing hands-on coding with mentoring junior team members and ensuring code quality across the team. They are also responsible for making architectural decisions, which requires staying updated on best practices and emerging Python frameworks. Additionally, coordinating collaboration between cross-functional teams (like DevOps, QA, and front-end developers) can be complex, especially in agile environments where requirements may shift rapidly. Overcoming these challenges helps foster a productive and innovative team culture.

What is the difference between Senior Python Developer vs Python Developer?

AspectSenior Python DeveloperPython Developer
Required ExperienceTypically 5+ years, with leadership and complex project experienceUsually 1-3 years, focusing on core Python skills
ResponsibilitiesDesigning architecture, mentoring, handling complex systemsWriting code, debugging, implementing features
CertificationsOptional but beneficial (e.g., Python certifications, cloud certs)Often not required
Work EnvironmentCollaborative teams, project planning, code reviewsDevelopment-focused, task-oriented

The main difference between a Senior Python Developer and a Python Developer lies in experience, responsibilities, and leadership. Senior developers handle complex projects, mentor others, and often participate in architecture decisions, while Python Developers focus on coding and feature implementation. Both roles are essential in tech companies, but the senior role requires more experience and broader skills.

Are senior Python developers still in demand?

Senior Python developers remain in high demand due to the language's versatility in web development, data analysis, machine learning, and automation. Companies seek experienced developers with skills in frameworks like Django or Flask, and proficiency in cloud platforms and APIs enhances job prospects.

How much does a senior Python developer make?

A senior Python developer typically earns between $100,000 and $150,000 annually, depending on experience, location, and industry. They often possess strong skills in frameworks like Django or Flask and may hold certifications or advanced degrees that influence salary levels.

What does a senior Python developer do?

A senior Python developer designs, develops, and maintains complex software applications using Python. They often lead projects, review code, optimize performance, and collaborate with cross-functional teams, requiring strong problem-solving skills and knowledge of frameworks like Django or Flask. Additionally, they may mentor junior developers and ensure code quality through testing and best practices.

What are the most commonly searched types of Python Developer jobs in Memphis, TN?

The most popular types of Python Developer jobs in Memphis, TN are:

What are popular job titles related to Senior Python Developer jobs in Memphis, TN?

For Senior Python Developer jobs in Memphis, TN, the most frequently searched job titles are:

What job categories do people searching Senior Python Developer jobs in Memphis, TN look for?

The top searched job categories for Senior Python Developer jobs in Memphis, TN are:

What cities near Memphis, TN are hiring for Senior Python Developer jobs?

Cities near Memphis, TN with the most Senior Python Developer job openings:

Senior Python Developer jobs near you
Infographic showing various Senior Python Developer job openings in Memphis, TN as of August 2026, with employment types broken down into 1% Internship, 85% Full Time, 8% Part Time, and 6% Contract. Highlights an 80% Physical, 6% Hybrid, and 14% Remote job distribution, with an average salary of $137,924 per year, or $66.3 per hour.

Senior Image Data Scientist-Center for Bioimage Informatics

St. Jude Childrens Research Hospital

Memphis, TN • On-site

$86K - $154K/yr

Other

Re-posted 8 days ago

St. Jude Children's Research Hospital rating

8.6

Company rating: 8.6 out of 10

Based on 12 frontline employees who took The Breakroom Quiz

43rd of 1,060 rated hospitals

Job description

The Center for Bioimage Informatics at St. Jude Children's Research Hospital is seeking two Senior Image Data Scientists to design, develop, validate, document, and operate image-analysis pipelines and visualization solutions for biomedical imaging research. This role works closely with investigators, software engineers, data scientists, imaging facility scientists, and biostatisticians to translate scientific questions into reproducible, scalable analysis workflows using modern image analysis, statistical, computer vision, and machine learning approache
The successful candidate will support image data management, maintain analysis software and repositories, evaluate new methods and tools, and provide technical consultation and training to research teams. This role also serves as a project lead to coordinate image-analysis efforts, align related projects, and contribute to shared CBI infrastructure that supports routine and advanced bioimage analysis.
Applicant Statement:
Applicants are encouraged to include a brief cover letter or supplemental statement with a link to representative work, such as a public repository, napari plugin, published pipeline, or comparable artifact. The statement should briefly describe one end-to-end image-analysis project or software tool the applicant has owned in production, including the biological or scientific question, data scale, methods or model used, pipeline design, validation approach, user adoption, and resulting impact.
Preferred Qualifications:
  • PhD in a relevant quantitative, computational, biomedical, or scientific field.

  • Experience developing, validating, and maintaining image-analysis pipelines for biological or medical imaging data.

  • Strong programming skills in Python and experience with modern computer vision, machine learning, deep learning, or statistical image-analysis methods.

  • Experience with emerging AI methods relevant to bioimage analysis, including vision transformers, foundation models, generative AI, large language models (LLMs), or agentic AI tools.

  • Experience with scalable and reproducible scientific workflows (e.g., Snakemake, Nextflow), containers, version control, and HPC or cloud environments.

  • Demonstrated experience using modern bioimaging tools, data standards, and open-source ecosystems such as napari, ImageJ/Fiji, Cellpose, SAM-family and related foundation segmentation models, QuPath, BioFormats, OME-Zarr/NGFF, or similar platforms.

  • Experience with large image data volumes, image data management, quality control, benchmarking, annotation strategies, and method evaluation.

  • Demonstrated ability to collaborate with research teams, communicate technical results clearly, write user-facing documentation, and provide training through courses, workshops, seminars, or similar formats.

  • Evidence of technical leadership, such as leading multi-lab projects, contributing to shared infrastructure, publishing methods, or contributing to open-source scientific software.

Minimum Education and/or Training:
  • Bachelor's degree in applied mathematics, physics, chemistry, bioinformatics, computer science, data science, computer engineering or related field required.
  • Master's degree preferred.

Minimum Experience:
  • Minimum Requirement: Bachelor's degree with 3+ years of work experience in relevant area (e.g., applied mathematics, physics, chemistry, bioinformatics, computer science, data science, computer engineering) required.
  • Experience Exception: Master's degree with 1+ years of relevant experience.
  • Experience in image analyses, image data management, and programming (e.g., Python, R, Matlab, Java, C/C++).
  • Experience in image analysis platforms (e.g., ImageJ/Fiji, CellProfiler), scientific computing, scientific data visualization, scientific computer code optimization and evaluation in an HPC environment, development of algorithms, statistical methods or scientific software, working with large image data volumes, biological/medical imaging preferred.
  • Proven performance in earlier role/comparable role.

Compensation
In recognition of certain U.S. state and municipal pay transparency laws, St. Jude is including a reasonable estimate of the compensation range for this role. This is an estimate offered in good faith and a specific salary offer takes into account factors that are considered in making compensation decisions including but not limited to skill sets, experience and training, licensure and certifications, and other business and organizational needs. It is not typical for an individual to be hired at or near the top of the salary range and compensation decisions are dependent on the facts and circumstances of each case. A reasonable estimate of the current salary range is $86,320 - $154,960 per year for the role of Senior Image Data Scientist-Center for Bioimage Informatics.
Explore our exceptional benefits!
St. Jude is an Equal Opportunity Employer
No Search Firms
St. Jude Children's Research Hospital does not accept unsolicited assistance from search firms for employment opportunities. Please do not call or email. All resumes submitted by search firms to any employee or other representative at St. Jude via email, the internet or in any form and/or method without a valid written search agreement in place and approved by HR will result in no fee being paid in the event the candidate is hired by St. Jude.

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