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Senior Python Automation Jobs in Missouri (NOW HIRING)

MasterCard

Senior Platform Engineer

O Fallon, MO · On-site

$97.80K - $134.20K/yr

We are responsible for automation standards with Mastercard, maintaining industry standard tools ... Java, Python, Go, Groovy, Perl or Ruby Strong skills designing, implementing, and enhancing ...

ClickHouse

$94.50K - $124.60K/yr

You'll work across a range of areas - from control plane services and automation to operational ... Strong programming experience in one or several of Ruby , Go , Rust, C or Python (and willingness ...

MasterCard

Senior Software Engineer

O Fallon, MO

$114.60K - $151.10K/yr

Strict Must-Haves (Non-Negotiable) Python - Proven experience building and operationalizing ... automation, and performance monitoring Experience designing and building microservices, APIs, and ...

Kemper

Senior Developer - BAW Specialist

Saint Louis, MO · On-site

$55.75 - $71/hr

The ideal candidate will bring deep technical skills in IBM Business Automation Workflow (BAW) as a ... Exposure to Python and Generative AI tools or platforms (e.g., OpenAI, AWS Bedrock, etc.). * Deep ...

Mastercard, Inc.

Senior Platform Engineer

O Fallon, MO · On-site

$114.60K - $151.10K/yr

We are responsible for automation standards with Mastercard, maintaining industry standard tools ... Java, Python, Go, Groovy, Perl or Ruby • Strong skills designing, implementing, and enhancing ...

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Senior Python Automation information

Is Python automation a good career?

Python automation is a strong career choice due to high demand for automation skills across industries such as IT, finance, and manufacturing. Professionals in this field often work with tools like Selenium, Jenkins, and scripting to improve efficiency, with opportunities for growth and certification in Python programming. It offers a stable job market and the potential for remote work and specialization.
What are the most commonly searched types of Python Automation jobs in Missouri? The most popular types of Python Automation jobs in Missouri are:
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Senior Python Automation jobs near you
Infographic showing various Senior Python Automation job openings in Missouri as of May 2026, with employment types broken down into 1% Internship, 84% Full Time, 9% Part Time, 1% Temporary, 4% Contract, and 1% Nights. Highlights an 77% Physical, 5% Hybrid, and 18% Remote job distribution.
Sr. Hyperautomation Engineer (UIpath & AI/ML)

Sr. Hyperautomation Engineer (UIpath & AI/ML)

Staffingine LLC

Saint Louis, MO • On-site

Contractor

Posted 17 days ago

Job description

Job Title:  Sr. Hyperautomation Engineer (UIpath & AI/ML)
Job Location: St. Louis, Mo
Job Type: Contract

Job Description:

We are looking for a highly experienced and certified Senior hyperautomation Engineer who will drive transformation within our team The ideal candidate will possess deep expertise in UiPath and Google Cloud Platform GCP and will be responsible for hands on development in both automation and AI/ML technologies

What You’ll Do

As a Senior Hyperautomation Engineer you will bridge complex business needs with cutting edge automation capabilities. You will architect develop and deploy scalable Agentic AI Automation solutions integrated with internal and external services. This role also involves mentoring junior engineers and collaborating with cross functional teams

Your key responsibilities will include

  • Lead the end-to-end development lifecycle for complex business processes focusing on RPA Agentic AI and Machine Learning ML Responsible for the design and development of solutions using core technologies such as UiPath Google DocAI Vertex AI Agent Builder and Conversational Generative AI.
  • System Integration Vision Implement complex agentic workflows integrated with key platforms and services including GCP services Cloud Functions PubSub Cloud Storage and BigQuery Observability tools Langfuse Enterprise applications Salesforce and ServiceNow and all external internal systems via APIs and direct database connections
  • Collaboration and Leadership Work closely with Operations and Business Units to identify and analyze complex processes determining their optimal suitability for Agentic AI and automation Furthermore the role requires you to mentor and guide junior engineers and regularly conduct code reviews.
  • Ensure adherence Best practices toward development coding standards quality check and validations technical documentation performance optimization and continuous improvement.

Recommended Qualification and Experience

  • Experience 10 years of overall IT experience with 5 years in development using UiPath IDP and RAG UiPath Advanced Developer Certification is recommended with strong understanding of RE Framework Orchestrator and Studio
  • To excel in this pivotal role you will possess a strong blend of analytical rigor technical understanding and collaborative spirit
  • Process Expertise Advanced Business Process Analysis BPA and Business Process Model and Notation BPMN skills enabling you to articulate and optimize complex workflows
  • Methodology Soft Skills Excellent problemsolving abilities and strong experience with change management processes Bring speed and accuracy by using Agile Scrum methodologies
  • AI Requirements Engineering Proven experience in AI requirements engineering translating business needs into detailed specifications for AI and Machine Learning components
  • AILLM Insight A deep understanding of AI and LLM Large Language Model capabilities and limitations allowing you to participate in design practical and effective intelligent solutions
  • Exceptional Communication Strong communication skills that bridge the gap between technical teams and business stakeholders effectively conveying complex ideas and fostering collaboration
  • If you are a detailoriented with a passion for leveraging AI to streamline operations and drive significant business impact we invite you to apply Join us in building the next generation of intelligent automation solutions.

Preferred Skill

  • Possesses prior experience in Java or Python scripting as well as experience with Salesforce and GCP Google Cloud Platform. Proficient in system integrations utilizing technologies such as SQL REST APIs and Google Kubernetes Engine GKE