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Senior Manufacturing Process Engineer Jobs in California

TekWissen LLC

Manufacturing Process Engineer

Vacaville, CA · On-site

$25 - $31/hr

Manufacturing Process Engineer Location: Vacaville, CA Duration: 6 months Job Type: Temporary Position Work Type: Onsite Summary This role provides hands-on technical support for Process Analytical ...

BBSI Client

Manufacturing Process Engineer

Vacaville, CA · On-site

$75K - $90K/yr

Vacaville, CA - On-site The Opportunity BBSI has partnered with a specialized Northern California-based engineering, manufacturing, and service company that designs, builds, installs, and maintains ...

Nikkiso Co.

Manufacturing Process Engineer II

Santa Ana, CA · On-site

$76K - $102K/yr

Job Overview The Manufacturing Process Engineer is responsible for optimizing manufacturing processes to improve quality, delivery, and cost performance across the operation. This role provides day ...

Nikkiso

Manufacturing Process Engineer II

Santa Ana, CA · On-site

$76K - $102K/yr

Job Overview The Manufacturing Process Engineer is responsible for optimizing manufacturing processes to improve quality, delivery, and cost performance across the operation. This role provides day ...

Nikkiso Cryogenic Industries

$75K - $100K/yr

Job Overview The Manufacturing Process Engineer is responsible for optimizing manufacturing processes to improve quality, delivery, and cost performance across the operation. This role provides day ...

Oclaro

Senior Wafer Process Engineer

San Jose, CA · On-site

$87K - $125K/yr

Senior Manufacturing Process Engineer (Mfg Waferfab) We value our talented employees, and whenever possible strive to help one of our associates grow professionally before recruiting new talent to ...

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Senior Manufacturing Process Engineer information

See California salary details

$74K

$119.5K

$168.3K

How much do senior manufacturing process engineer jobs pay per year?

As of Sep 13, 2026, the average yearly pay for senior manufacturing process engineer in California is $119,530.00, according to ZipRecruiter salary data. Most workers in this role earn between $102,600.00 and $132,700.00 per year, depending on experience, location, and employer.

What does a senior manufacturing process engineer do?

A Senior Manufacturing Process Engineer is responsible for designing, analyzing, and improving manufacturing processes to increase efficiency, quality, and safety in production environments. They lead projects to implement new technologies, troubleshoot process issues, and optimize workflows. They also work closely with cross-functional teams to ensure that products meet industry standards and regulatory requirements. Additionally, they mentor junior engineers and support continuous improvement initiatives within the organization.

What are the main challenges a senior manufacturing process engineer faces when implementing process improvements?

One of the primary challenges Senior Manufacturing Process Engineers encounter is balancing the need for process innovation with maintaining production efficiency and product quality. Implementing new technologies or methodologies often requires extensive cross-functional collaboration, training, and sometimes overcoming resistance to change from team members. Additionally, ensuring that process improvements comply with industry regulations and safety standards can add complexity. However, these challenges provide valuable opportunities to develop leadership skills and drive significant impact within the organization.

What are the key skills and qualifications needed to thrive as a senior manufacturing process engineer, and why are they important?

To thrive as a Senior Manufacturing Process Engineer, you need a strong background in engineering principles, process optimization, and manufacturing systems, typically with a bachelor's or master's degree in engineering and relevant industry experience. Familiarity with CAD/CAM software, Lean Six Sigma methodologies, and statistical process control tools is highly valued, along with certifications such as Six Sigma Green or Black Belt. Exceptional problem-solving abilities, leadership, and effective communication are crucial soft skills for driving process improvements and collaborating across teams. These skills ensure efficient production, high product quality, and continuous operational enhancements in a competitive manufacturing environment.

What is the difference between Senior Manufacturing Process Engineer vs Manufacturing Engineer?

AspectSenior Manufacturing Process EngineerManufacturing Engineer
Required CredentialsBachelor's degree in engineering, 5+ years experience, possibly certifications like Six SigmaBachelor's degree in engineering or related field, 1-3 years experience
Work EnvironmentOversees process improvements, leads projects, collaborates with cross-functional teamsSupports manufacturing operations, implements process changes, troubleshoots production issues
Employer & Industry UsageUsed in manufacturing plants, automotive, aerospace, electronics industriesCommon in similar industries, entry to mid-level roles in manufacturing

The main difference is that a Senior Manufacturing Process Engineer typically has more experience, takes on leadership roles, and oversees complex process improvements, while a Manufacturing Engineer focuses on supporting and implementing manufacturing processes at a more operational level.

What are popular job titles related to Senior Manufacturing Process Engineer jobs in California?

For Senior Manufacturing Process Engineer jobs in California, the most frequently searched job titles are:

What job categories do people searching Senior Manufacturing Process Engineer jobs in California look for?

The top searched job categories for Senior Manufacturing Process Engineer jobs in California are:

What cities in California are hiring for Senior Manufacturing Process Engineer jobs?

Cities in California with the most Senior Manufacturing Process Engineer job openings:

Senior Manufacturing Process Engineer jobs near you
Infographic showing various Senior Manufacturing Process Engineer job openings in California as of September 2026, with employment types broken down into 100% Full Time. Highlights an 100% In-person job distribution, with an average salary of $119,530 per year, or $57.5 per hour.

Manufacturing Process Engineer

Vacaville, CA • On-site

TekWissen LLC
Recruiting and Staffing Services • 501 - 1,000 employees
Learn more about TekWissen LLCexternal

$25 - $31/hr

Temporary

Re-posted 19 days ago

Job description

Overview:  
 
TekWissen group is a workforce management provider throughout the USA and many other countries in the world. Our client is a leading biotechnology company that combines technological expertise with world-class manufacturing and scientific insight to support the delivery of innovative medicines for a wide range of diseases. Specializing in pharmaceutical ingredients, bioscience, biopharmaceuticals, custom manufacturing, and cell and gene therapy, the company provides comprehensive services across the pharmaceutical, biotech, and life sciences sectors. It supports every stage of drug development, from early research to commercial production, and offers solutions in biologics, small molecules, and specialty ingredients. Committed to quality and innovation, the company serves as a critical partner in advancing therapeutic solutions and streamlining complex manufacturing processes, with a global presence that ensures access to scalable, flexible, and compliant technical expertise.
 
 
Job Title:         Manufacturing Process Engineer
Location:         Vacaville, CA
Duration:        6 months 
Job Type:        Temporary Position
Work Type:    Onsite
 
 
Summary
 
This role provides hands-on technical support for Process Analytical Technology (PAT) systems deployed on the manufacturing floor in a large-scale biopharmaceutical facility. These systems are critical for monitoring mammalian cell culture processes, including parameters such as cell density, viability, and metabolite concentrations. Ensuring system reliability and readiness is essential to maintaining consistent manufacturing performance.
The role supports daily operation, maintenance, troubleshooting, and repair of PAT instruments used in GMP manufacturing. The individual will collaborate closely with the Frontline Upstream (FLUS) System Owner, Manufacturing, and Instrumentation teams to assess system issues, conduct health checks, implement improvements, and support investigations related to unplanned events. This position also supports the deployment of multiple new PAT systems alongside existing instruments and offers valuable hands-on experience with advanced analytical technologies used in mammalian cell culture and purification operations.
Key Accountabilities:
  • Perform routine maintenance, calibration checks, and system readiness activities for PAT instruments such as cell counters and metabolic analyzers (e.g., Cedex Bio, Cedex HiRes, Cedex Cobas).
  • Support manufacturing operations by responding to system-related issues, troubleshooting instrument performance, and documenting observations.
  • Assist in investigating unplanned equipment events using structured problem-solving tools and contribute to root cause analysis.
  • Conduct equipment health monitoring and support reliability improvement initiatives to enhance system uptime.
  • Execute planned equipment modifications, minor upgrades, and configuration updates under guidance from the PAT System Owner.
  • Review and interpret instrument data to identify trends and abnormalities.
  • Support adherence to data integrity principles and maintain data consistency within data management systems.
  • Collaborate with Manufacturing, FLUS, Automation, QA, and external vendors to ensure optimal system performance.
  • Assist with documentation updates, work tracking, and preparation of technical summaries.
  • Work independently to complete assigned tasks while providing regular progress updates to stakeholders.
Required Qualifications
  • B.S., M.S., or Ph.D. in Engineering or a scientific/analytical discipline.
  • Prior hands-on experience with analytical systems.
  • Experience with cell counters and metabolite analyzers such as Cedex Bio, Cedex HiRes, and Cedex Cobas in GMP manufacturing or QC laboratory settings.
  • Experience troubleshooting analytical instruments and interpreting equipment performance data.
  • General understanding of biotech analytical methods and laboratory practices.
  • Strong verbal and written communication skills, including documentation and reporting.
  • Ability to work independently and manage responsibilities with minimal supervision.
  • Strong interpersonal skills with the ability to collaborate effectively across cross-functional teams.
  • Demonstrated ability to evaluate technical issues and implement corrective actions.
  • Familiarity with data management systems; experience with Smartline Data Cockpit is highly desirable.
  • Strategic thinking mindset with the ability to translate system requirements into actionable activities.
  • Flexibility in problem-solving and work hours to meet business objectives.
  • Ability to build strong working relationships with end users and equipment vendors.
  • Customer-focused approach with strong partnership-building skills.
  • Working knowledge of current Good Manufacturing Practices (cGMPs) in biopharmaceutical or regulated manufacturing environments.
TekWissen® Group is an equal opportunity employer supporting workforce diversity.

TekWissen is an emerging global human capital, recruitment and IT services organization. Operating since 2009, we draw upon more than a decade of staffing experience to deliver critical talent acquisition solutions and IT engagements for our clients. We’re founded on a culture that is passionate about delivering tailored solutions, that create lasting partnerships.

Our global footprint covers six countries: United States, Canada, Australia, India, United Kingdom and the Philippines. This allows us to work in close partnership with organizations and manage everything from global talent needs with demanding resourcing strategies, to single sites with lower recruitment volumes.

TekWissen® is an equal opportunity employer supporting workplace diversity. 

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About TekWissen

Sourced by ZipRecruiter

TekWissen is an emerging global human capital, recruitment and IT services organization. Operating since 2009, we draw upon more than a decade of staffing experience to deliver critical talent acquisition solutions and IT engagements for our clients. We’re founded on a culture that is passionate about delivering tailored solutions, that create lasting partnerships.

Industry

Recruiting and staffing services

Company size

501 - 1,000 Employees

Headquarters location

Ann Arbor, MI, US

Year founded

2009

Social media

Twitter

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