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Senior Manager Statistical Programming Jobs (NOW HIRING)

Penumbra

Manager, Statistical Programming

The Manager of Statistical Programming provides statistical programming support for multiple projects through own efforts and those of staff for assigned projects. The manager builds relationships ...

Amgen, Inc.

Statistical Programming, Sr Manager

Statistical Programming, Sr Manager What you will do Let's do this. Let's change the world. In this vital role you will ensure all statistical aspects pertaining to clinical activities meet required ...

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Senior Manager Statistical Programming information

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How much do senior manager statistical programming jobs pay per year?

As of Aug 7, 2026, the average yearly pay for senior manager statistical programming in the United States is $99,008.00, according to ZipRecruiter salary data. Most workers in this role earn between $87,000.00 and $107,000.00 per year, depending on experience, location, and employer.

What is the difference between Senior Manager Statistical Programming vs Statistical Programmer?

AspectSenior Manager Statistical ProgrammingStatistical Programmer
CredentialsBachelor's/Master's in Biostatistics, Computer Science, or related field; often with management experienceBachelor's or Master's in Biostatistics, Statistics, or related field
Work EnvironmentLeads teams, manages projects, collaborates with cross-functional teamsPerforms data analysis, programming, and validation tasks under supervision
Employer & Industry UsagePharmaceutical, biotech companies, CROs, clinical researchPharmaceutical, biotech, clinical research organizations

The main difference is that Senior Manager Statistical Programming oversees teams and manages projects, while Statistical Programmers focus on executing data analysis and programming tasks. The senior role involves leadership responsibilities, whereas the programmer role is more technical and task-oriented.

What are the key skills and qualifications needed to thrive as a senior manager statistical programming, and why are they important?

To thrive as a Senior Manager Statistical Programming, you need expertise in biostatistics, programming languages like SAS or R, and experience with clinical trial data, typically supported by an advanced degree in a quantitative field. Familiarity with regulatory requirements (e.g., CDISC standards), clinical data management systems, and project management tools is essential. Strong leadership, communication, and problem-solving skills help you lead teams and liaise with cross-functional stakeholders. These skills ensure accurate, compliant data analyses and effective team management for successful clinical trial outcomes.

How does a senior manager statistical programming typically collaborate with cross-functional teams in clinical research projects?

A Senior Manager Statistical Programming plays a pivotal role in coordinating with biostatisticians, clinical data managers, and medical writers to ensure seamless data flow and analysis throughout clinical trials. They oversee programming teams to deliver statistical outputs, such as tables, listings, and figures, while maintaining compliance with regulatory standards. Regular meetings and clear communication are essential, as the Senior Manager must interpret project requirements and translate them into actionable programming tasks, ensuring timelines and quality standards are met. This collaborative environment fosters continuous learning and problem-solving, as cross-functional input is vital for addressing complex data challenges.
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Senior Manager Statistical Programming jobs near you
Infographic showing various Senior Manager Statistical Programming job openings in the United States as of August 2026, with employment types broken down into 88% Full Time, 11% Part Time, and 1% Contract. Highlights an 85% Physical, 2% Hybrid, and 13% Remote job distribution, with an average salary of $99,008 per year, or $47.6 per hour.

Senior Manager, Statistical Programming (Oncology)

BioNTech SE

Gaithersburg, MD • On-site, Remote

$130K - $209K/yr

Full-time

Medical, Dental, Vision, Life, Retirement, PTO

Re-posted 16 days ago

Job description

Cambridge, US; Gaithersburg, US; New Jersey, US   |   full time   |   Job ID: 11351 

About the Role

As a Senior Manager, Statistical Programming at BioNTech, you will be instrumental in ensuring high-quality statistical programming deliverables that support our clinical development projects. Working collaboratively with Clinical Development teams or CROs, you will oversee the creation and validation of programming outputs for study reports and regulatory submissions. Your expertise will drive process efficiencies, uphold quality standards, and contribute to the development of global programming tools and standards. Join us to help advance groundbreaking therapies in oncology and infectious diseases.

Your Contribution

  • Collaborate with Clinical Development teams or CROs to meet project timelines for statistical data analysis and reporting
  • Oversee or independently produce and validate programming deliverables such as analysis datasets, tables, listings, and figures
  • Anticipate resource needs and coordinate with management to ensure long-term resource allocation for therapeutic projects
  • Ensure quality control (QC) is performed on all derived datasets, tables, listings, and figures in alignment with company standards and regulatory requirements
  • Participate in developing global programming standards to enable consistent deliverables across portfolios; create tools supporting SDTM/ADaM dataset generation and TLF production
  • Provide functional expertise in establishing BioNTech's centralized clinical data repository, clinical data dictionary, and operational data dictionary
  • Collaborate with Biostatistics to develop statistical applications such as data review and reporting tools
  • Support regulatory submissions by preparing data submission packages including define.xml

A Good Match

  • BSc in Statistics, Mathematics, Computer Science, or related discipline; advanced degree preferred
  • 5+ years (3+ years with advanced degree) experience in pharmaceutical industry/CRO/clinical research settings
  • Strong competence in statistical programming (e.g., SAS/Base, Macro, STAT, GRAPH, SQL)
  • Solid knowledge of FDA/EMA/ICH regulations and guidelines governing clinical trials
  • Familiarity with industry standards for clinical study data reporting (e.g., CDISC standards)
  • Experience in oncology therapeutic area; submission experience preferred
  • Project management skills with strong organizational abilities and attention to detail
  • Excellent communication skills (written/spoken English) with a proactive mindset for problem-solving
  • Ability to thrive in a fast-paced team environment while maintaining analytical rigor

Your benefits and remuneration:

Expected Pay Range: $130,800/year to $209,400/year + benefits, annual bonus & equity (bonus and equity is variable and dependent on company and individual performance). Compensation for the role will depend on several factors, including responsibilities of the job, education, experience, knowledge, skills, and abilities.

BioNTech US is committed to employee wellbeing and offers best-in-class benefits & HR programs to support an inclusive & diverse workforce. Salaried/Position-Targeted Hourly Employees working 30+ hours per week are eligible for our comprehensive benefits package. Benefits include but are not limited to:

  • Medical, Dental and Vision Insurance
  • Life, AD&D, Critical Illness Insurance
  • Pre-tax HSA & FSA, DCRA Spending Accounts
  • Employee Assistance & Concierge Program (EAP) available 24/7
  • Parental and Childbirth Leave & Family Planning Assistance
  • Sitterstream: Virtual Tutoring & Childcare Membership
  • Paid Time Off: Vacation, Sick, Bereavement, Holidays (including Floating) & Year-End U.S. Shutdown.
  • 401(K) Plan with Company Match
  • Tuition Reimbursement & Student Loan Assistance Programs
  • Wellbeing Incentive Platforms & Incentives
  • Professional Development Programs
  • Commuting Allowance and subsidized parking
  • Discounted Home, Auto & Pet Insurance

...and more! More details to be shared.
 

Apply now - We look forward to your application!

Apply for our Cambridge, US; Gaithersburg, US; New Jersey, US location and simply send us your documents using our online form.

By submitting your application, you acknowledge that a background check will be conducted as part of the recruitment process in accordance with applicable laws and regulations. If you are considered for the position, BioNTech will conduct the background check through our service provider 'HireRight'. You will be informed accordingly by your BioNTech-Recruiter.

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