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Senior Manager Statistical Programming Jobs (NOW HIRING)

Biogen

Sr Analyst, Statistical Programming

Cambridge, MA · On-site

$95K - $130K/yr

... role The Senior Analyst, Statistical Programming leads and oversees statistical programming ... Leads, coordinates and manages timely creation, oversight, review, completion, and delivery of ...

Biogen

NC · On-site

$95K - $130K/yr

... role The Senior Analyst, Statistical Programming leads and oversees statistical programming ... Leads, coordinates and manages timely creation, oversight, review, completion, and delivery of ...

AstraZeneca

Director, Statistical Programming

Waltham, MA · On-site

$168K - $253K/yr

Are you an experienced Manager and Leader in Statistical Programming with a deep knowledge of clinical drug development and line management experience? Would you like to be part of a fast-paced and ...

AstraZeneca

Director, Statistical Programming

Waltham, MA · On-site

$168K - $253K/yr

Are you an experienced Manager and Leader in Statistical Programming with a deep knowledge of clinical drug development and line management experience? Would you like to be part of a fast-paced and ...

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Senior Manager Statistical Programming information

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How much do senior manager statistical programming jobs pay per year?

As of Jun 27, 2026, the average yearly pay for senior manager statistical programming in the United States is $99,008.00, according to ZipRecruiter salary data. Most workers in this role earn between $87,000.00 and $107,000.00 per year, depending on experience, location, and employer.

What are Senior Manager Statistical Programming?

A Senior Manager Statistical Programming is a leadership role in the field of clinical research and biostatistics, typically within the pharmaceutical, biotechnology, or contract research organization (CRO) industries. This professional oversees teams of statistical programmers responsible for analyzing clinical trial data, ensuring data accuracy, and delivering high-quality statistical outputs for regulatory submissions. The role involves project management, resource allocation, mentoring staff, and collaborating with cross-functional teams to ensure compliance with regulatory standards and timelines.

What is the difference between Senior Manager Statistical Programming vs Statistical Programmer?

AspectSenior Manager Statistical ProgrammingStatistical Programmer
CredentialsBachelor's/Master's in Biostatistics, Computer Science, or related field; often with management experienceBachelor's or Master's in Biostatistics, Statistics, or related field
Work EnvironmentLeads teams, manages projects, collaborates with cross-functional teamsPerforms data analysis, programming, and validation tasks under supervision
Employer & Industry UsagePharmaceutical, biotech companies, CROs, clinical researchPharmaceutical, biotech, clinical research organizations

The main difference is that Senior Manager Statistical Programming oversees teams and manages projects, while Statistical Programmers focus on executing data analysis and programming tasks. The senior role involves leadership responsibilities, whereas the programmer role is more technical and task-oriented.

What are the key skills and qualifications needed to thrive as a Senior Manager Statistical Programming, and why are they important?

To thrive as a Senior Manager Statistical Programming, you need expertise in biostatistics, programming languages like SAS or R, and experience with clinical trial data, typically supported by an advanced degree in a quantitative field. Familiarity with regulatory requirements (e.g., CDISC standards), clinical data management systems, and project management tools is essential. Strong leadership, communication, and problem-solving skills help you lead teams and liaise with cross-functional stakeholders. These skills ensure accurate, compliant data analyses and effective team management for successful clinical trial outcomes.

How does a Senior Manager Statistical Programming typically collaborate with cross-functional teams in clinical research projects?

A Senior Manager Statistical Programming plays a pivotal role in coordinating with biostatisticians, clinical data managers, and medical writers to ensure seamless data flow and analysis throughout clinical trials. They oversee programming teams to deliver statistical outputs, such as tables, listings, and figures, while maintaining compliance with regulatory standards. Regular meetings and clear communication are essential, as the Senior Manager must interpret project requirements and translate them into actionable programming tasks, ensuring timelines and quality standards are met. This collaborative environment fosters continuous learning and problem-solving, as cross-functional input is vital for addressing complex data challenges.
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Senior Manager Statistical Programming jobs near you
Infographic showing various Senior Manager Statistical Programming job openings in the United States as of June 2026, with employment types broken down into 20% Full Time, 74% Part Time, 3% Temporary, and 3% Contract. Highlights an 85% Physical, 2% Hybrid, and 13% Remote job distribution, with an average salary of $99,008 per year, or $47.6 per hour.
Director, Statistical Programming

Director, Statistical Programming

AstraZeneca

Boston, MA • On-site

Full-time

Medical, Dental, Vision, Retirement, PTO

This job post has expired today. Applications are no longer accepted.

AstraZeneca rating

8.6

Company rating: 8.6 out of 10

Based on 43 frontline employees who took The Breakroom Quiz

16th of 73 rated pharmaceutical

Job description

This is what you will do:
The Director of Statistical Programming will be primarily responsible for overseeing statistical programming activities for multiple clinical studies within multiple Therapeutic Areas, maintaining programming infrastructure and ensuring compliance with SOPs to produce quality and timely deliverables. He/she must possess extensive experience and proven skills in the use of SAS within a Statistical Programming environment and complete knowledge and understanding of the statistical programming processes, procedures, and roles. He/she will use knowledge of CDISC SDTM and ADaM standards to support Biostatistics in statistical analysis, including generating analysis data listing, tables, and figures and create all files necessary to support an electronic submission in the eCTD format. Additionally, the successful candidate will use his/her strong people management skills and supervisory skills to provide direct line management to statistical programmers and external partners, identify training needs and opportunities for optimizing staff utilization and employing the most efficient practices. He/she must be able to identify project resource requirement needs and manage large external provider contract budgets. He/she may be responsible for the direct-line management of the statistical programmers through Associate Director level staff.
You will be responsible for:
  • Serve as the Lead Programmer and Manager of the statistical programming efforts for a compound / indication.

  • Develop and validate technical programming specifications for analysis datasets using Alexion or ADaM standards.

  • Independently develop and validate programs that generate analysis datasets based on Alexion or ADaM specifications.

  • Develop and validate technical programming specifications for protocol specific efficacy tables, listings, figures/graphs.

  • Independently develop and validate programs that generate protocol specific efficacy tables, listings, figures/graphs using Alexion specifications.

  • Ensuring that the filing of study documentation is maintained to the standard required according to processes and acceptable for audit.

  • Provide secondary reviews of Statistical Programming deliverables.

  • Directly support the Statistical Programming Sr. Director in all aspects of the management and development of the Statistical Programming team.

  • Participate in the ongoing review of the processes used by the Statistical Programming group to ensure processes are continually complied with and updated as necessary.

  • Create and/or review programming plans and ensure appropriate resource allocation and prioritization.

  • Act as the primary department contact, when necessary, to ensure that department standards are implemented in all studies.

  • Manage adherence to all company policies, SOPs, and other controlled documents; and ensure all programming activities adhere to departmental standards.

  • Assume direct line management responsibility of the statistical programmers, conducting performance reviews, setting and regularly reviewing objectives, providing guidance and mentoring, and developing and regularly reviewing training and career development plans.

  • Plan and manage department budget. Forecast quarter, annual, and 3-5 year budget. Participate in strategic development meetings across departments.

  • Evaluate, develop, revise, implement and ensure compliance to functional guidelines, policies, and SOPs.

  • Collaborate across all functional areas to ensure programming needs are met with specific regards to study data specifications, applications and computing environment support.

  • Collaborate closely with Biostatistics, Clinical Data Management, Pharmacovigilance, Clinical Operations, and other functions within Alexion to address their needs for programming support.

  • Collaborate closely with Preferred Vendor management in terms of governance, recruiting needs, contract development and signature, and any other partnership requirement that may arise.

  • Any other activities as required.

Any other activities as required.
The duties of this role are generally conducted in an office environment. As is typical of an office-based role, employees must be able, with or without an accommodation to: use a computer; engage in communications via phone, video, and electronic messaging; problem solve; engage in complex and non-linear thought, analysis, and dialogue; collaborate with others; maintain general availability during standard business hours.
You will need to have:
  • 10+ years statistical programming experience in the CRO or Pharmaceutical Industry.

  • 7+ years people and / or project management experience in the CRO or Pharmaceutical Industry.

  • Advanced SAS programming skills in a clinical and statistical data environment across multiple therapeutic areas.

  • Thorough understanding of relational databases and their correlation to submission ready database structure.

  • Strong project management skills and experience with scope management, resource management, financial management, project planning and resource allocation

  • Significant experience in a leadership capacity with a focus on identifying, leading and advancing talent.

  • Experience working in a clinical development organization with a heavy emphasis on support of multiple, ongoing projects

  • Thorough understanding of pharmaceutical clinical development (i.e. understanding of statistical concepts, techniques, and clinical trial principles) and ability to manage and lead regulatory submissions.

  • Thorough understanding of industry standards such as CDISC and 21CFR Part 11.

  • Strong ability to solve problems, recommend process improvements, and execute on process improvements.

  • Ability to lead and influence teams

  • Excellent verbal and written communication skills in a global environment.

  • Proven ability to work with cross functional teams, specifically Data Management, Biostatistics, Epidemiology, Clinical Operations, and Pharmacovigilance to initiate, lead and execute new initiatives and process improvements.

  • Recognize behaviors that align with our values critical to the success of our employees, mission, and business objectives.

We would prefer for you to have:
  • BS/MS/MA in Statistics, Biostatistics, Computer Science, Mathematics or related area.

  • Competencies

  • Accountability

  • Collaboration

  • Decision Quality

  • Drive for Results

  • Perseverance

  • Problem Solving

  • Informing

  • Peer Relationships

  • Time Management

  • Building Effective Teams

  • Managing Through Systems

The annual base pay (or hourly rate of compensation) for this position ranges from $165,095.20 - $247,642.80. Our positions offer eligibility for various incentives-an opportunity to receive short-term incentive bonuses, equity-based awards for salaried roles and commissions for sales roles. Benefits offered include qualified retirement programs, paid time off (i.e., vacation, holiday, and leaves), as well as health, dental, and vision coverage in accordance with the terms of the applicable plans.
Date Posted
09-Jun-2026
Closing Date
25-Jun-2026
Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees. In furtherance of that mission, we welcome and consider applications from all qualified candidates, regardless of their protected characteristics. If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form.

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