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Senior Full Stack Software Developer Jobs in Ohio

Senior Software Engineer

Dayton, OH · On-site

$119.10K - $157K/yr

Senior Software Engineer Position Type: Full-time Location: Dayton, OH (Primary); Huntsville, AL ... This role focuses on designing, developing, and integrating modern full stack applications, with an ...

Senior Software Engineer

Dayton, OH

$119.10K - $157K/yr

Senior Software Engineer Position Type: Full-time Location: Dayton, OH (Primary); Huntsville, AL ... This role focuses on designing, developing, and integrating modern full stack applications, with an ...

AI Full stack Software Engineer

Columbus, OH · Remote

$110.30K - $183.80K/yr

We are seeking a highly skilled and motivated AI Full Stack Software Engineer to join our ... Effective communication skills to collaborate with technical, DevOps and product management teams.

AI Full stack Software Engineer

Columbus, OH · Remote

$110.30K - $183.80K/yr

We are seeking a highly skilled and motivated AI Full Stack Software Engineer to join our ... Effective communication skills to collaborate with technical, DevOps and product management teams.

AI Full stack Software Engineer

Columbus, OH · Remote

$110.30K - $183.80K/yr

We are seeking a highly skilled and motivated AI Full Stack Software Engineer to join our ... Effective communication skills to collaborate with technical, DevOps and product management teams.

Full Stack Java Developer

Columbus, OH · On-site

$49.50 - $63.75/hr

Hi, Title- Java Developer Location- Columbus, OH | Onsite Role- Contract We are seeking an experienced Senior Full Stack Java Developer with 12+ years of hands-on experience in designing, developing ...

Senior Software Engineer

Cincinnati, OH · On-site +1

$117.50K - $154.90K/yr

As a Senior Software Engineer, you will be joining one of our agile teams responsible for ... You will use your full-stack software engineering experience to develop a mix of custom and third ...

Senior Software Engineer

Dayton, OH

$115.70K - $152.60K/yr

... features, and supporting DevOps and CI/CD practices to streamline development and deployment ... Minimum 5 years of experience in full-stack web development * Experience with front-end frameworks ...

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Showing results 1-20

Senior Full Stack Software Developer information

See Ohio salary details

$22

$56

$81

How much do senior full stack software developer jobs pay per hour?

As of May 29, 2026, the average hourly pay for senior full stack software developer in Ohio is $56.34, according to ZipRecruiter salary data. Most workers in this role earn between $46.83 and $64.90 per hour, depending on experience, location, and employer.

What are the key skills and qualifications needed to thrive as a Senior Full Stack Software Developer, and why are they important?

A Senior Full Stack Software Developer needs advanced proficiency in both front-end and back-end programming languages, strong problem-solving skills, and several years of relevant software development experience. Familiarity with frameworks like React or Angular, back-end technologies such as Node.js or Django, and experience with cloud platforms, CI/CD tools, and version control systems like Git are typically required. Excellent communication, teamwork, and leadership abilities help developers collaborate effectively and mentor junior team members. These skills are crucial for designing robust, scalable applications and leading complex projects to successful completion.

What types of projects and technologies can a Senior Full Stack Software Developer expect to work on, and how does the team typically collaborate?

As a Senior Full Stack Software Developer, you can expect to work on a diverse range of projects such as developing scalable web applications, integrating APIs, and optimizing system performance. The tech stack often includes front-end frameworks like React or Angular, back-end environments such as Node.js, Python, or Java, and databases like PostgreSQL or MongoDB. Collaboration is highly cross-functional—you’ll regularly coordinate with product managers, UX/UI designers, QA engineers, and other developers through agile methodologies, code reviews, and sprint planning sessions. This role offers opportunities to mentor junior developers, influence architectural decisions, and contribute to continuous process improvement.

What is a Senior Full Stack Software Developer?

A Senior Full Stack Software Developer is an experienced professional who designs, develops, and maintains both the front-end and back-end components of web applications. They are proficient in multiple programming languages and frameworks, enabling them to work on the entire technology stack, from databases and servers to user interfaces. In addition to coding, they often lead projects, mentor junior developers, and help architect scalable solutions that meet business needs. Their role requires strong problem-solving skills, a deep understanding of software development best practices, and the ability to collaborate with cross-functional teams.

What is the difference between Senior Full Stack Software Developer vs Software Engineer?

AspectSenior Full Stack Software DeveloperSoftware Engineer
CredentialsBachelor's degree in CS or related field; experience in full stack developmentBachelor's degree in CS or related field; may have certifications in specific technologies
Work EnvironmentCollaborates across front-end and back-end teams, often in agile settingsDesigns, develops, and maintains software applications, often in teams or individually
Industry UsageCommon in tech companies, startups, and agencies requiring versatile development skillsWidely used across industries for software development roles

While both roles involve software development, a Senior Full Stack Software Developer specializes in both front-end and back-end technologies, often taking on leadership responsibilities. A Software Engineer may focus on specific areas of software design and implementation, with less emphasis on full stack expertise. The roles overlap in skills and industry usage, but the senior developer typically has broader responsibilities and experience in full stack development.

What are the most commonly searched types of Full Stack Software Developer jobs in Ohio? The most popular types of Full Stack Software Developer jobs in Ohio are:
What cities in Ohio are hiring for Senior Full Stack Software Developer jobs? Cities in Ohio with the most Senior Full Stack Software Developer job openings:
Infographic showing various Senior Full Stack Software Developer job openings in Ohio as of May 2026, with employment types broken down into 74% Full Time, 25% Part Time, and 1% Contract. Highlights an 88% Physical, 1% Hybrid, and 11% Remote job distribution, with an average salary of $117,185 per year, or $56.3 per hour.
Senior AI Full stack Software Engineer

Senior AI Full stack Software Engineer

McKesson

Columbus, OH • Remote

$131K - $218.30K/yr

Full-time

Posted 9 days ago


McKesson rating

7.8

Company rating: 7.8 out of 10

Based on 198 frontline employees who took The Breakroom Quiz

39th of 70 rated pharmaceutical


Job description

McKesson is an impact-driven, Fortune 10 company that touches virtually every aspect of healthcare. We are known for delivering insights, products, and services that make quality care more accessible and affordable. Here, we focus on the health, happiness, and well-being of you and those we serve - we care.

What you do at McKesson matters. We foster a culture where you can grow, make an impact, and are empowered to bring new ideas. Together, we thrive as we shape the future of health for patients, our communities, and our people. If you want to be part of tomorrow's health today, we want to hear from you.

We are seeking a highly skilled and experienced Senior AI Full Stack Software Engineer to join our innovative team at CMM. This role involves designing, developing, and deploying end-to-end AI-powered solutions, from robust backend services to intuitive user interfaces, to enhance our healthcare and decision-making platforms.

Key Responsibilities

  • Lead AI-Driven Healthcare Solutions: Design and deploy AI applications that support decision-making, patient engagement, and operational efficiency.

  • Integrate AI into EHRs and Clinical Systems: Build scalable systems that incorporate LLMs, voice/image recognition, and document parsing into existing healthcare IT infrastructure.

  • Develop and Optimize Data Pipelines: Ensure secure, HIPAA-compliant data pipelines for training and deploying AI models using structured and unstructured healthcare data (e.g., clinical notes, imaging, lab results).

  • Model Evaluation and Compliance: Apply rigorous evaluation metrics (e.g., sensitivity, specificity, AUC-ROC) and ensure models meet regulatory and ethical standards.

  • Mentor and Lead: Guide junior engineers and contribute to the strategic direction of AI initiatives within the organization.

  • Rapid AI prototyping and iteration with product representatives to vet multiple concepts

Minimum Qualifications

  • 10+ years of software engineering experience, with 4+ years in AI/ML development.

  • B.S. degree in Computer Science or related engineering discipline, or equivalent experience

Critical Skills

  • 2+ years of experience building AI solutions in healthcare or life sciences.

  • Deep understanding of healthcare data standards (e.g., HL7, FHIR) and compliance frameworks (e.g., HIPAA, GDPR).

  • Healthcare AI Expertise: Proven ability to build AI models for clinical NLP, medical imaging, patient risk stratification, and care personalization.

  • LLM & RAG Systems: Skilled in building retrieval-augmented generation systems using tools likePydantic, Semantic Kernel,LangChain,LlamaIndex, and vector databases.

  • Experienced in creating custom AI agents or spec-driven tools.

  • Experience writing skills for Claude, Copilot, Codex etc.

  • Prompt Engineering & Optimization: Advanced techniques for prompt tuning, caching, and benchmarking.

  • Full Stack Development: Proficiency in Python, Node.js, and modern web frameworks.

Preferred Skills

  • Cloud & DevOps: Experience with secure cloud environments (AWS/GCP/Azure), containerization (Docker, Kubernetes), and CI/CD pipelines.

  • AI Tooling: Familiarity with OpenAI, Hugging Face,PyDanticAI, TensorFlow,PyTorch, and healthcare-specific AI libraries.

  • Communication & Leadership: Ability to communicate complex AI concepts to clinical and executive stakeholders and lead cross-functional teams.

  • Experience mentoring and developing juniors in development an AI concepts/best practices.

We are proud to offer a competitive compensation package at McKesson as part of our Total Rewards. This is determined by several factors, including performance, experience and skills, equity, regular job market evaluations, and geographical markets. The pay range shown below is aligned with McKesson's pay philosophy, and pay will always be compliant with any applicable regulations. In addition to base pay, other compensation, such as an annual bonus or long-term incentive opportunities may be offered. For more information regarding benefits at McKesson, pleaseclick here.

Our Base Pay Range for this position

$131,000 - $218,300

McKesson has become aware of online recruiting-related scams in which individuals who are not affiliated with or authorized by McKesson are using McKesson's (or affiliated entities, like CoverMyMeds or RxCrossroads) name in fraudulent emails, job postings or social media messages. In light of these scams, please bear the following in mind:
McKesson Talent Advisors will never solicit money or credit card information in connection with a McKesson job application.


McKesson Talent Advisors do not communicate with candidates via online chatrooms or using email accounts such as Gmail or Hotmail. Note that McKesson does rely on a virtual assistant (Gia) for certain recruiting-related communications with candidates.

McKesson job postings are posted on our career site: careers.mckesson.com.

McKesson is an Equal Opportunity Employer

McKesson provides equal employment opportunities to applicants and employees, without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability, age, genetic information, or any other legally protected category. For additional information on McKesson's full Equal Employment Opportunity policies, visit our Equal Employment Opportunity page.

McKesson is committed to being an Equal Employment Opportunity Employer and offers opportunities to all job seekers including job seekers with disabilities. If you need a reasonable accommodation to assist with your job search or application for employment, please contact us by sending an email to (United States) Disability_Accommodation@McKesson.com or (Canada) Accessibility@mckesson.ca. Resumes or CVs submitted to this email box will not be accepted.

Join us at McKesson!


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