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Remote Startup Jobs in North Carolina (NOW HIRING)

Aquatech International LLC

... startup readiness, and operational success for highly complex industrial utility systems associated with advanced manufacturing facilities. This can be a fully remote job. The successful candidate ...

Aquatech International LLC

This is a remote position. Unlike a traditional Project Manager role focused primarily on ... Construction, Startup, and Operational Readiness Coordinate field execution activities including ...

Aquatech International LLC

Drive program performance related to scope, schedule, cost, quality, safety, risk, startup readiness, and customer satisfaction. * Ensure project teams remain focused on achieving customer ...

Protopia

$14.50 - $19.50/hr

Extra Awesome Would Be * Prior startup marketing experience (great if consumer technology ... remote but occasionally can be found at The Frontier & HQ Raleigh coworking spaces.

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Remote Startup information

See North Carolina salary details

$75.9K

$115.4K

$155.4K

How much do remote startup jobs pay per year?

As of Aug 29, 2026, the average yearly pay for remote startup in North Carolina is $115,446.00, according to ZipRecruiter salary data. Most workers in this role earn between $99,100.00 and $130,400.00 per year, depending on experience, location, and employer.

What is a remote startup?

A remote startup is a newly established company where the founders and employees work from different locations, rather than from a central office. These startups leverage digital tools and online platforms to communicate, collaborate, and manage projects remotely. This model allows for greater flexibility, access to a global talent pool, and reduced operational costs. However, it also presents challenges in communication, team cohesion, and time zone coordination. Remote startups have become increasingly popular, especially in the tech industry, due to advancements in remote work technology.

What are remote jobs working for startups?

Remote startup jobs exist in various industries. The duties of these virtual positions vary but typically involve taking part in the development of processes, products, and services for a new business. Since these are virtual positions, you handle your responsibilities over the internet. As a software developer at a startup, you may code and test products or create internal programs that a startup can use on their computer network. As a graphic designer, you may create various images and visual elements for the website and/or product packaging. Startups also need remote business development specialists and accountants to create a development plan, make decisions, and handle the company’s finances.

What are the key skills and qualifications needed to thrive as a remote startup founder, and why are they important?

To thrive as a Remote Startup Founder, you need strong entrepreneurial skills, business acumen, and a solid understanding of your industry, often supported by prior startup or leadership experience. Familiarity with project management tools (like Asana or Trello), remote collaboration platforms (such as Slack or Zoom), and basic financial or analytics software is critical. Exceptional communication, self-motivation, adaptability, and the ability to inspire and lead a distributed team are standout soft skills. These skills and qualifications are vital to successfully launch, manage, and scale a business in a remote environment where clear direction and effective collaboration are crucial.

What unique challenges might I face working for a remote startup, and how can I succeed in this environment?

Working for a remote startup often means adapting to a fast-paced, constantly evolving environment where clear communication and self-motivation are crucial. You may encounter challenges such as managing time across different time zones, handling ambiguity in your role, and building relationships with colleagues you rarely meet in person. To thrive, it's important to proactively communicate, embrace flexibility, and be willing to take initiative on projects. Additionally, leveraging digital collaboration tools and maintaining regular check-ins with your team can help you stay aligned and connected.
More about Remote Startup jobs

What are the most commonly searched types of Startup jobs in North Carolina?

The most popular types of Startup jobs in North Carolina are:

What job categories do people searching Remote Startup jobs in North Carolina look for?

The top searched job categories for Remote Startup jobs in North Carolina are:

What cities in North Carolina are hiring for Remote Startup jobs?

Cities in North Carolina with the most Remote Startup job openings:

Remote Startup jobs near you
Infographic showing various Remote Startup job openings in North Carolina as of August 2026, with employment types broken down into 94% Full Time, 3% Part Time, 2% Contract, and 1% Nights. Highlights an 78% Physical, 3% Hybrid, and 19% Remote job distribution, with an average salary of $115,446 per year, or $55.5 per hour.

Site Contracts Manager II (Sponsor-Dedicated/ Remote - US only)

Syneoshealth

Concord, NC • On-site, Remote

$82K - $110K/yr

Full-time

Medical, Dental, Vision, Retirement, PTO

Posted 17 days ago

Syneos Health rating

8.1

Company rating: 8.1 out of 10

Based on 22 frontline employees who took The Breakroom Quiz

38th of 86 rated pharmaceutical

Job description

Site Contracts Manager II (Sponsor-Dedicated/ Remote - US only)

Syneos Health is a leading fully-integrated life sciences services organization built to accelerate customer success. We partner with innovators at every point across the drug development and commercialization continuum, helping them navigate complexity, anticipate change and accelerate progress.
Our Clinical Solutions team members act with a drug development mindset, applying their years of experience and deep expertise to truly understand customer needs and represent those in the solutions we shape.
Whether you join us in a Functional Service Provider partnership or a Full-Service environment, you'll collaborate with passionate problem solvers, innovating as a team to help our customers achieve their goals. We are agile and driven to deliver - for one another, our customers, and, most importantly, for those in need.
Discover what your 25,000 future colleagues already know:
Why Syneos Health
We are passionate about developing our people, through career development and progression; supportive and engaged line management; technical and therapeutic area training; peer recognition and total rewards program.
We are committed to building an inclusive culture - where you can authentically be yourself. Central to this is our purpose - Driven to Deliver - which captures the passion of our colleagues to show up each day and shape solutions that have the ability to dramatically impact someone's life.
We are continuously building the company we all want to work for and our customers want to work with. Why? Because we know that when we bring together smart colleagues from across the world, we can shape the future of healthcare, driving impact for customers and defining the pace of patient progress.

Job Responsibilities

Site Contracts Manager II (Sponsor-Dedicated)

Remote - United States

Are you a clinical contracts professional who thrives on negotiation, stakeholder collaboration, and delivering results in a fast-paced environment? Do you enjoy partnering directly with investigative sites and major academic institutions to develop creative contract and budget solutions that accelerate study startup timelines?

We are seeking a Site Contracts Manager II to support a Sponsor-Dedicated program focused on Pharma and Vaccine clinical trials. This role serves as a key partner in the development, negotiation, and management of site budgets and Clinical Trial Agreements (CTAs), ensuring contracts are executed efficiently while minimizing legal, operational, and financial risk.

This is an excellent opportunity for an experienced site contracts professional who enjoys balancing contract strategy, budget negotiations, relationship management, and operational execution across multiple therapeutic areas, including oncology.

WHAT YOU WILL DO

As a Site Contracts Manager II, you will serve as a subject matter expert for site budgets and contracts, partnering with investigative sites, academic institutions, sponsors, and cross-functional stakeholders to ensure timely execution of agreements that support clinical trial startup and study conduct.

Site Budget Development & Negotiation

  • Develop, review, and negotiate site budgets from sponsor-approved templates.

  • Lead end-to-end budget negotiations directly with investigative sites and study teams.

  • Evaluate proposed budgets for alignment with sponsor expectations and Fair Market Value (FMV) principles.

  • Support budget strategy discussions and provide recommendations to internal stakeholders.

  • Manage budget-related escalations and facilitate resolution of negotiation challenges.

  • Perform budget due diligence activities when sites do not proceed with the initial offer.

Site Contract Development & Negotiation

  • Draft, review, negotiate, and finalize Clinical Trial Agreements (CTAs) and associated contract documents.

  • Lead negotiations directly with large academic institutions, academic medical centers, and investigative sites.

  • Develop detailed contract specifications that support business objectives while minimizing legal, operational, and financial risk.

  • Review proposed contract language and determine when legal or business escalations are required.

  • Secure necessary approvals for contract language or budget escalations.

  • Support timely contract execution while ensuring compliance with sponsor requirements.

Project Leadership & Study Delivery

  • Independently manage multiple contracting projects simultaneously across various therapeutic areas.

  • Prioritize workload and drive deliverables to meet study startup timelines and business objectives.

  • Partner with Clinical Operations, Legal, Finance, and Study Start-Up teams throughout the contracting lifecycle.

  • Identify and proactively escalate risks, delays, and issues that may impact contract execution timelines.

  • Support studies involving complex startup activities and key milestones, including Site Initiation Visits (SIVs).

Compliance & Risk Management

  • Conduct due diligence reviews, including FMV assessments and site justification evaluations.

  • Ensure compliance with sponsor SOPs, policies, work instructions, and applicable regulations.

  • Maintain current knowledge of ICH-GCP guidelines, industry regulations, sponsor processes, and emerging technologies.

  • Apply sound risk assessment principles during contract review and negotiation activities.

Systems, Reporting & Operational Excellence

  • Maintain accurate and timely updates within contract management systems, databases, and departmental trackers.

  • Utilize Excel and clinical trial management tools to manage workflow, reporting, and study metrics.

  • Ensure documentation remains complete, accurate, and audit-ready.

  • Participate in process improvement initiatives designed to enhance efficiency, productivity, and overall quality.

  • Contribute ideas and solutions that simplify contracting workflows and reduce operational waste.

Collaboration & Team Support

  • Build and maintain strong relationships with internal and external stakeholders.

  • Demonstrate excellent written and verbal communication skills while incorporating feedback into deliverables.

  • Support training, onboarding, and mentoring activities as needed.

  • Foster a culture of trust, transparency, accountability, and collaboration.

  • Lead and support special projects, initiatives, and ad hoc requests as assigned.

WHO YOU ARE

Required Qualifications

  • Minimum of 2 years of direct experience negotiating clinical trial budgets and contracts.

  • Direct experience negotiating with large academic institutions, academic medical centers, and investigative sites

  • Bachelor's degree or equivalent combination of education and relevant experience.

  • Minimum of 2 years of experience in a fast-paced, high-volume clinical research, pharmaceutical, CRO, or investigative site environment.

  • Experience developing and negotiating Clinical Trial Agreements (CTAs) and site budgets.

  • Demonstrated ability to manage multiple priorities, lead projects, and deliver results within challenging timelines.

  • Strong understanding of:

    • Clinical Trial Agreements (CTAs)

    • Site budget development and negotiation

    • Fair Market Value (FMV) principles

    • Clinical trial startup processes

    • Clinical study protocols and timelines

    • Site-related milestones, including SIV readiness

    • ICH-GCP guidelines and clinical research regulations

  • Strong negotiation, communication, and stakeholder management skills.

  • Advanced proficiency with Microsoft Excel and clinical trial management systems.

Preferred Qualifications

  • Experience in the oncology therapeutic area.

  • Experience supporting Pharma and/or Vaccine studies.

  • Experience working within a pharmaceutical company, CRO, or investigative site setting.

  • Experience supporting studies across multiple therapeutic areas.

  • Strong project management and cross-functional leadership skills.

  • Experience leveraging AI tools within the clinical contracting and budgeting environment.

  • Experience supporting process improvement and operational excellence initiatives.

WHY YOU WILL LOVE THIS OPPORTUNITY

  • Support a dedicated pharmaceutical sponsor partnership.

  • Lead complex contract and budget negotiations with major academic institutions and research sites.

  • Manage high-visibility clinical trial startup activities across diverse therapeutic areas.

  • Collaborate with Clinical Operations, Legal, Finance, and Study Start-Up stakeholders.

  • Develop expertise across Pharma and Vaccine clinical development programs.

  • Enjoy the flexibility of a fully remote, US-based position.

  • Join a collaborative team committed to innovation, operational excellence, and continuous improvement.

If you are an experienced clinical contracts professional with a passion for negotiation, project leadership, and stakeholder collaboration, we encourage you to apply and make an immediate impact on critical clinical development programs.

At Syneos Health, we believe in providing an environment and culture in which Our People can thrive, develop and advance. We reward and recognize our people by providing valuable benefits and a quality-of-life balance. The benefits for this position may include a company car or car allowance, Health benefits to include Medical, Dental and Vision, Company match 401k, eligibility to participate in Employee Stock Purchase Plan, Eligibility to earn commissions/bonus based on company and individual performance, and flexible paid time off (PTO) and sick time. Because certain states and municipalities have regulated paid sick time requirements, eligibility for paid sick time may vary depending on where you work. Syneos complies with all applicable federal, state, and municipal paid sick time requirements.

Salary Range:

$47,000.00 - $95,900.00

The base salary range represents the anticipated low and high of the Syneos Health range for this position. Actual salary will vary based on various factors such as the candidate's qualifications, skills, competencies, and proficiency for the role.

Get to know Syneos Health


Over the past 5 years, we have worked with 94% of all Novel FDA Approved Drugs, 95% of EMA Authorized Products and over 200 Studies across 73,000 Sites and 675,000+ Trial patients.

No matter what your role is, you'll take the initiative and challenge the status quo with us in a highly competitive and ever-changing environment. Learn more about Syneos Health.

http://www.syneoshealth.com

Additional Information


Tasks, duties, and responsibilities as listed in this job description are not exhaustive. The Company, at its sole discretion and with no prior notice, may assign other tasks, duties, and job responsibilities. Equivalent experience, skills, and/or education will also be considered so qualifications of incumbents may differ from those listed in the Job Description. The Company, at its sole discretion, will determine what constitutes as equivalent to the qualifications described above. Further, nothing contained herein should be construed to create an employment contract. Occasionally, required skills/experiences for jobs are expressed in brief terms. Any language contained herein is intended to fully comply with all obligations imposed by the legislation of each country in which it operates, including the implementation of the EU Equality Directive, in relation to the recruitment and employment of its employees. The Company is committed to compliance with the Americans with Disabilities Act, including the provision of reasonable accommodations, when appropriate, to assist employees or applicants to perform the essential functions of the job.

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