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Remote Second Shift Engineer Jobs in Boston, MA (NOW HIRING)

Oakwell

Mechanical Engineer

Boston, MA · Remote

$110K - $140K/yr

Multiple remote opportunities available. What you'll drive You will work alongside senior Oakwell ... Working collaboratively in a team is second nature to you. * You thrive in ambiguity and changing ...

Oakwell

Senior Mechanical Engineer

Boston, MA · Remote

$107K - $141K/yr

This is a remote opportunity with a preference that candidates be located in the Northeast** What ... Working collaboratively in a team is second nature to you. * You thrive in ambiguity and changing ...

Allego

Junior Support Engineer

Waltham, MA · On-site +1

$55K - $65K/yr

Support Engineer will provide second tier, technical support utilizing application expertise ... Ability to work independently as part of a team that is largely remote * Bachelor's Degree ...

Databento

Software Engineer (C++/Rust)

Boston, MA · On-site +1

Optimize existing codebase for high throughput (millions of messages per second, up to 40+ gigabits ... Good communication skills and work ethic for a remote workplace. * An interest in low-level ...

Care Access

Senior Engineer, Test Automation

Boston, MA · Remote

$130K - $180K/yr

Partner with engineers during active development to shift quality left -- writing tests alongside ... Remote within the United States. This role requires 100% of work to be performed in a remote office ...

ezCater, Inc

Staff GRC Engineer (Remote)

Boston, MA · On-site +1

Help shift the program from detective-only controls toward stronger preventive and engineering-embedded control patterns where appropriate. * Expand data security policy and program quality * Help ...

Broadcom

Solution Engineer - ValueOps

Boston, MA · Remote

Solution Engineer - Remote Are you ready to take on a senior Domain Specialist role collaborating ... Skills necessary to shift customer from relationship to partnership * Strong background with ...

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All JobsSecond Shift Engineer JobsRemote Second Shift Engineer JobsRemote Second Shift Engineer Jobs in Boston, MA

Remote Second Shift Engineer information

See Boston, MA salary details

$20

$39

$73

How much do remote second shift engineer jobs pay per hour?

As of Aug 13, 2026, the average hourly pay for remote second shift engineer in Boston, MA is $39.95, according to ZipRecruiter salary data. Most workers in this role earn between $27.16 and $48.03 per hour, depending on experience, location, and employer.

What are the key skills and qualifications needed to thrive as a remote second shift engineer?

To thrive as a Remote Second Shift Engineer, you need strong technical troubleshooting abilities, a solid understanding of network and system administration, and relevant experience or certifications such as CompTIA Network+, Microsoft Certified: Azure Administrator, or Cisco CCNA. Familiarity with remote monitoring tools, ticketing systems like ServiceNow, and virtualization platforms is typically expected. Excellent communication, time management, and self-motivation are soft skills that set top performers apart in remote, off-hours roles. These skills and qualities are vital for ensuring reliable system support, rapid issue resolution, and seamless teamwork across different shifts and locations.

What are some common challenges faced by remote second shift engineers and how can they be addressed?

Remote Second Shift Engineers often encounter challenges such as coordinating with daytime teams across different time zones, managing communication gaps, and maintaining a work-life balance due to non-traditional hours. To address these, it's helpful to use collaboration tools for asynchronous updates, proactively schedule check-ins with team members, and establish a consistent routine that separates work from personal time. Employers often provide resources and support to help engineers stay connected and engaged with the broader team, ensuring both productivity and job satisfaction.

What is a remote second shift engineer?

A Remote Second Shift Engineer is a technical professional who works primarily during the second shift hours, typically in the late afternoon to evening, and performs their duties remotely. This role often involves monitoring systems, troubleshooting issues, and providing support outside of standard business hours to ensure continuous operation. Second shift engineers are crucial for organizations that require 24/7 technical support or need to accommodate clients and teams in different time zones. The remote aspect allows them to perform their duties from any location with reliable internet access. This position usually requires strong problem-solving skills, technical expertise, and the ability to work independently.

What is the difference between Remote Second Shift Engineer vs Remote Night Shift Technician?

AspectRemote Second Shift EngineerRemote Night Shift Technician
Required CredentialsBachelor's in Engineering or related field, technical certificationsTechnical certifications, associate's or bachelor's degree often preferred
Work EnvironmentRemote, project-based, collaborative teamsRemote or on-site, hands-on troubleshooting, equipment maintenance
Employer & Industry UsageManufacturing, energy, tech companiesManufacturing, utilities, tech support

The Remote Second Shift Engineer typically handles engineering tasks, system design, and troubleshooting remotely during evening hours, requiring technical credentials. The Remote Night Shift Technician focuses on equipment maintenance and repairs, often with hands-on work, during night hours. Both roles serve similar industries but differ mainly in job focus and responsibilities.

What are popular job titles related to Remote Second Shift Engineer jobs in Boston, MA? For Remote Second Shift Engineer jobs in Boston, MA, the most frequently searched job titles are:
What job categories do people searching Remote Second Shift Engineer jobs in Boston, MA look for? The top searched job categories for Remote Second Shift Engineer jobs in Boston, MA are:
What cities near Boston, MA are hiring for Remote Second Shift Engineer jobs? Cities near Boston, MA with the most Remote Second Shift Engineer job openings:
Remote Second Shift Engineer jobs near you
Infographic showing various Remote Second Shift Engineer job openings in Boston, MA as of August 2026, with employment types broken down into 100% Full Time. Highlights an 100% Remote job distribution, with an average salary of $83,097 per year, or $40 per hour.

Engineer, Biologics Purification, Upstream/Downstream/Tech Transfer - Remote (JP15407)

3 Key Consulting

Cambridge, MA • On-site, Remote

$34 - $37/hr

Full-time

Re-posted 23 days ago

Job description

Job Title: Engineer, Biologics Purification, Upstream/Downstream/Tech Transfer - Remote (JP15407)
Location: Cambridge MA, Remote
Employment Type: Contract
Business Unit: Drug Substance Technology Engineering Group
Duration: 1+ years with possible extensions and/or conversion to permanent
Posting Date: 5/21/2026
Pay Rate: $34 - $37/hour W2
Notes: Remote (Any TZ - Local to Cambridge, MA is highly preferred.
 
3 Key Consulting is hiring an Engineer for a consulting engagement with our direct client, a leading global biopharmaceutical company.
Job Description:
Seeking a Process Development Engineer to join the Drug Substance Technology Engineering team at our client Cambridge site. Providing strong process engineering/ technology transfer support of human therapeutic drug substance products in clinical development through commercial production. Our mission is to translate developmental processes to commercial reality for patients through scientific expertise and engineering innovation. Knowledge of processes/equipment; scale-up factors, process deviations, quality attributes. GMP experience is a plus.
The Engineer will apply upstream and downstream process engineering knowledge in support of technology transfer and clinical/commercial drug substance manufacturing in both stainless and single-use formats. Will partner with manufacturing, quality, analytical, and bench scientists to support a highly dynamic technology transfer.
JOB RESPONSIBILITIES:
Under guidance of senior staff, the Engineer will perform the following:
  • Transfer processes for drug substance manufacturing and translate process improvements from the laboratory into manufacturing facilities
  • Provide technical support for successful scale-up, transfer of process technology, and for clinical and/or commercial manufacturing operation. Experience is technical report writing an expectation.
  • Assist in troubleshooting clinical and commercial runs
  • Execute data trending and statistical process analysis
  • Support technical direction for process-related deviations, CAPAs, and change controls
  • Identify and support process-related operational excellence opportunities
  • Represent process development and collaborates with other functions such as Manufacturing, Quality, and Regulatory.
  • Experience related to Process characterization for manufacturing of biologics highly preferred. This includes technical support for authoring and review of process characterization reports.

Why is the Position Open?
Supplement additional workload on team.
BASIC QUALIFICATIONS:
Master’s degree and 2 years of Engineering or Operations experience
Bachelor’s degree and 4 years of Engineering or Operations experience
Associate’s degree and 7 years of Engineering or Operations experience
High school diploma / GED and 8 years of Engineering or Operations experience
PREFERRED QUALIFICATIONS:
  • Master’s Degree in Chemical or Biochemical Engineering
  • 2+ years of Process Engineering experience preferably related to downstream/ purification of commercial cGMP manufacturing facilities
  • Background in biologics technology transfer into commercial facilities, new product introductions (NPIs)
  • Biologics purification process knowledge: Knowledge of upstream ( cell culture/bioreactor operations) or purification processes (chromatography, viral filtration/inactivation, ultrafiltration/diafiltration, and final fill. )/ equipment; scale-up factors, process deviations, quality attributes
  • Strong analytical capability, troubleshooting, and problem solving
  • Independently motivated with ability to multi-task and work in teams, especially if remote or hybrid.
  • Excellent written and verbal communication skills with technical writing and presentation experience. Experience in PC documentation, report reviews and technical writing preferred.
     
Top Must Have Skills:
  • Cell culture experience, Purification /downstream experience, process characterization experience
  • Nice to have:
    Monoclonal antibodies or mAbs 
    manufacturing or on floor support 

Day to Day Responsibilities:
Assist senior staff in technical writing, process tech transfer, data monitoring
Red Flags:
No experience, not enough experience in biopharma or biotech, no experience in cell culture/upstream, purification/downstream or technical report writing
Interview process:
Teams interview. Screening 30 minute Microsoft team's interview with me. Second round- Team's interview 30 minute each approximately with 3 other team members.
We invite qualified candidates to send your resume to resumes@3keyconsulting.com.  If you decide that you’re not interested in pursuing this particular position, please feel free to take a look at the other positions on our website www.3keyconsulting.com/careers. You are also welcome to share this opportunity with anyone you think might be interested in applying for this role.